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Review Articles

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  • Ciofani et al., discuss the unique medical and pharmaceutical challenges in maintaining and supplying medical care for crews involved for human space missions beyond Low Earth Orbit, such as to the Moon and Mars. They highlight opportunities for repurposing existing innovative technologies and biomedical advances to support crew health during long-duration missions.

    • Gianni Ciofani
    • Tiziano Bandiera
    • Francesca Ferranti
    Review ArticleOpen Access
  • Kohabir et al. review recent advances in CRISPR-based diagnostics aimed at achieving single-nucleotide fidelity for clinical applications. By dissecting strategies in gRNA design, effector selection, and reaction conditions, the authors highlight how these innovations can support precise and accessible genetic testing at the point-of-care.

    • K. A. V. Kohabir
    • E. A. Sistermans
    • R. M. F. Wolthuis
    Review ArticleOpen Access
  • Boeckmans et al. discuss the importance of healthcare providers fully engaging with people with Metabolic dysfunction-associated steatotic liver disease (MASLD) and actively working with them to improve their metabolic health. They propose areas to focus on and provide a practical guide to healthcare practitioners in this area.

    • Joost Boeckmans
    • Hannes Hagström
    • Jörn M. Schattenberg
    Review ArticleOpen Access
  • Eisinger-Mathason et al. examine how data linkage transforms healthcare research by integrating diverse datasets. They also discuss privacy-preserving methods and challenges related to data quality and privacy.

    • T. S. Karin Eisinger-Mathason
    • Jonah Leshin
    • Abel N. Kho
    Review ArticleOpen Access
  • Sridhar et al. review the opportunities that mobile health technologies offer to improve the care of patients with cardiac arrhythmias. The current status, challenges, and future opportunities to use these technologies to predict, screen, diagnose, and manage of cardiac arrhythmias are highlighted.

    • Arun R. Sridhar
    • Jim W. Cheung
    • Dhanunjaya Lakkireddy
    Review ArticleOpen Access
  • Ng, Chaturvedi et al. discuss established, emerging, and promising biomarkers related to preeclampsia. They highlight novel approaches for screening these biomarkers at the point of care, aiming to democratize testing and reduce the burden of the disease.

    • Ka Wai Ng
    • Nandita Chaturvedi
    • Samuel Mabbott
    Review ArticleOpen Access
  • Vasudevan et al. discuss optical melanometry as a tool for objective, quantitative evaluation of skin pigmentation in studies addressing pulse oximeter racial disparity. The authors analyze research on commercial melanometer accuracy, discuss best practices for implementation and highlight promising future research directions.

    • Sandhya Vasudevan
    • William C. Vogt
    • T. Joshua Pfefer
    Review ArticleOpen Access
  • Koh, Papanikolaou et al. discuss the application of artificial intelligence in cancer imaging. The authors highlight opportunities for exploiting machine learning algorithms in this field, and outline barriers in their implementation and how these might be addressed.

    • Dow-Mu Koh
    • Nickolas Papanikolaou
    • Fred Prior
    Review ArticleOpen Access

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