Nature Search

Extensible Immunofluorescence (ExIF) accessibly generates high-plexity datasets by integrating standard 4-plex imaging data

Gunawan et al. propose an Extensible Immunofluorescence (ExIF) strategy that integrates distinct 4-plex image panels from routine fluorescence microscopy into multiplexed datasets enabling quantitative interrogation of complex, multimolecular single-cell processes.

Ihuan Gunawan
Felix V. Kohane
John G. Lock
ResearchOpen Access17 May 2025
Nature Communications

Volume: 16, P: 1-15
Robust and versatile ionic liquid microarrays achieved by microcontact printing

Ionic liquids are widely used in diverse applications as solvents with high thermal and chemical stability. Gunawan et al.develop a protocol for fabrication of an ionic liquid microdroplet array using a soft lithography technique, and demonstrate its utility as a membrane-free high-performance gas sensor.

Christian A. Gunawan
Mengchen Ge
Chuan Zhao
Research30 Apr 2014
Nature Communications

Volume: 5, P: 1-8
The role of vitamin C in melanoma cell death via activation of cytochrome C and TNF-α protein expression

Eva Krishna Sutedja
Tiara Rachmaputeri Arianto
Budi Setiabudiawan
ResearchOpen Access06 Oct 2025
Scientific Reports

Volume: 15, P: 1-10
Implications for fault locking south of Jakarta from an investigation of seismic activity along the Baribis fault, northwestern Java, Indonesia

S. Widiyantoro
P. Supendi
A. Lesmana
ResearchOpen Access16 Jun 2022
Scientific Reports

Volume: 12, P: 1-10
Carrier-resolved photo-Hall effect

A carrier-resolved photo-Hall technique is developed to extract properties of both majority and minority carriers simultaneously and determine the critical parameters of semiconductor materials under light illumination.

Oki Gunawan
Seong Ryul Pae
Byungha Shin
Research07 Oct 2019
Nature

Volume: 575, P: 151-155
Author Correction: Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation

Yohei Morishita
Suze Ma
Brandon I. Morinaka
Amendments and Corrections17 Mar 2025
Nature Chemistry

Volume: 17, P: 624
Implications for megathrust earthquakes and tsunamis from seismic gaps south of Java Indonesia

S. Widiyantoro
E. Gunawan
H. E. Putra
ResearchOpen Access17 Sept 2020
Scientific Reports

Volume: 10, P: 1-11
Cytogenetic signatures favoring metastatic organotropism in colorectal cancer

The molecular basis of the preferential metastasis to specific organs in colorectal cancer (CRC) remains to be explored. Here, the authors identify the cytogenetic events that favor metastatic colonization at specific sites by studying cohorts of primary CRCs and metastases.

Mariola Monika Golas
Bastian Gunawan
Bjoern Sander
ResearchOpen Access05 Apr 2025
Nature Communications

Volume: 16, P: 1-19
Unveiling ECRAM switching mechanisms using variable temperature Hall measurements for accelerated AI computation

Kwak et al. report AC magnetic parallel dipole line Hall measurements on electrochemical random-access memory based on WO_3-x, which determine the oxygen donor level and reveal that conductance potentiation even at low temperature is caused by an increase in both mobility and carrier density.

Hyunjeong Kwak
Junyoung Choi
Seyoung Kim
ResearchOpen Access19 Mar 2025
Nature Communications

Volume: 16, P: 1-11
The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish

The endocardium lines the interior of the heart chambers and has been debated as a source of hematopoietic lineages. Here they show that the endocardium may act as a source of, and resident tissue for, hematopoietic stem and progenitor cells in zebrafish, providing evidence for diversity in origins and residences of hematopoietic cells.

Dorothee Bornhorst
Amulya V. Hejjaji
Felix Gunawan
ResearchOpen Access31 Aug 2024
Nature Communications

Volume: 15, P: 1-19
Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation

Radical SAM (rSAM) and 2-His-1-carboxylate enzymes are known to co-occur in RiPP biosynthetic pathways. Here we show the fusion of these enzymes in a single protein where the rSAM enzyme catalyzes cyclophane formation. The 2-His-1-carboxylate enzymes—termed αKG-HExxH—are α-ketoglutarate non-haem iron enzymes that harbour a distinct fold and catalyse β-hydroxylation.

Yohei Morishita
Suze Ma
Brandon I. Morinaka
Research18 Sept 2024
Nature Chemistry

Volume: 16, P: 1882-1893
Distinct mechanisms regulate ventricular and atrial chamber wall formation

Albu et al. show that muscle cells in the cardiac atrium construct structures through heterogeneous cell behaviors that are different, at the cellular and molecular levels, from those involved during ventricular chamber maturation.

Marga Albu
Eileen Affolter
Didier Y. R. Stainier
ResearchOpen Access17 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Histologic chorioamnionitis and fat mass accretion in infants born preterm

Emily Gunawan
Viral G. Jain
Ariel A. Salas
ResearchOpen Access19 Sept 2025
Pediatric Research

P: 1-8
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

Ezh2 is a protein methylase that epigenetically modifies chromatin. Su and colleagues identify a cytoplasmic role for Ezh2 whereby it controls the extravasation of innate leukocytes through methylation of talin and thereby influences inflammatory responses in vivo.

Merry Gunawan
Nandini Venkatesan
I-hsin Su
Research09 Mar 2015
Nature Immunology

Volume: 16, P: 505-516
Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

Autosomal dominant polycystic kidney disease (ADPKD) is a complicated disease that involves numerous cell types. Here the authors used a multiomics approach consisting of single nucleus transcriptomes and epigenomes to redefine cell states in ADPKD and to dissect the cellular interactions and molecular mechanisms of ADPKD.

Yoshiharu Muto
Eryn E. Dixon
Benjamin D. Humphreys
ResearchOpen Access30 Oct 2022
Nature Communications

Volume: 13, P: 1-19
Proteolysis regulates cardiomyocyte maturation and tissue integration

Proper heart development and synchronous cardiomyocyte contraction rely on tissue integrity. Here the authors show that the ubiquitin-proteasome system and the E3 ubiquitin ligase ASB2 in particular are crucial for cardiomyocyte maturation and tissue integrity through the degradation of the TCF3 transcription factor.

Ryuichi Fukuda
Felix Gunawan
Didier Y. R. Stainier
ResearchOpen Access17 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Spin–valley phase diagram of the two-dimensional metal–insulator transition

O. Gunawan
T. Gokmen
M. Shayegan
Research15 Apr 2007
Nature Physics

Volume: 3, P: 388-391
Molecular landscape of respiratory infection: A large-scale, multi-centre blood transcriptome dataset

Tracy Chew
Tiana M. Pelaia
Maryam Shojaei
ResearchOpen Access10 Jul 2025
Scientific Data

Volume: 12, P: 1-7
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease

Abnormal alveolar development and homeostasis are common features of pulmonary disease. Here the authors show that Myh10 expression is reduced in emphysema patients, and that Myh10 loss of function impairs alveolar formation and lung morphogenesis via upregulation of matrix metalloproteinase activity and altered matrix remodeling.

Hyun-Taek Kim
Wenguang Yin
Didier Y. R. Stainier
ResearchOpen Access02 Nov 2018
Nature Communications

Volume: 9, P: 1-13
Ultrathin high band gap solar cells with improved efficiencies from the world’s oldest photovoltaic material

Wide band gap semiconductors are important for the development of tandem photovoltaics. By introducing buffer layers at the front and rear side of solar cells based on selenium; Todorov et al., reduce interface recombination losses to achieve photoconversion efficiencies of 6.5%.

Teodor K. Todorov
Saurabh Singh
Richard Haight
ResearchOpen Access25 Sept 2017
Nature Communications

Volume: 8, P: 1-8
The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis

Tubulogenesis is required for the formation of many internal structures including the trachea. Here, the authors show that the potassium channel KCNJ13 regulates tracheal tube formation, with shorter tracheas forming in mutant mice due in part to changes in actin organization in tracheal smooth muscle cells.

Wenguang Yin
Hyun-Taek Kim
Didier Y. R. Stainier
ResearchOpen Access19 Jul 2018
Nature Communications

Volume: 9, P: 1-13
Ground-based measurements of column-averaged carbon dioxide molar mixing ratios in a peatland fire-prone area of Central Kalimantan, Indonesia

Windy Iriana
Kenichi Tonokura
Dodo Gunawan
ResearchOpen Access31 May 2018
Scientific Reports

Volume: 8, P: 1-7
Kiam wood, Cotylelobium lanceotatum, extract as a natural antimicrobial agent: protecting Pacific white shrimp, Penaeus vannamei, against vibriosis

Muhamad Amin
Jirayu Buatong
Soottawat Benjakul
ResearchOpen Access17 Apr 2025
Scientific Reports

Volume: 15, P: 1-17
Immune-mediated regeneration of cell-free vascular grafts in an ovine model

Bita Nasiri
Arundhati Das
Stelios T. Andreadis
ResearchOpen Access19 Mar 2025
npj Regenerative Medicine

Volume: 10, P: 1-15
The genetic variation and relationship among the natural hybrids of Mangifera casturi Kosterm

Deden Derajat Matra
Muh Agust Nur Fathoni
Roedhy Poerwanto
ResearchOpen Access05 Oct 2021
Scientific Reports

Volume: 11, P: 1-10
Factors underlying the neurofunctional domains of the Addictions Neuroclinical Assessment assessed by a standardized neurocognitive battery

Tommy Gunawan
Jeremy W. Luk
David Goldman
ResearchOpen Access02 Jul 2024
Translational Psychiatry

Volume: 14, P: 1-12
Prevalence of burnout and its determinants among Indonesian nurses: a multicentre study

I. Gede Juanamasta
Yupin Aungsuroch
Rapin Polsook
ResearchOpen Access30 Dec 2024
Scientific Reports

Volume: 14, P: 1-9
Genie: the first open-source ISO/IEC encoder for genomic data

Genie, an open-source encoder compliant with ISO/IEC’s MPEG-G standard, delivers state-of-the-art genomic data compression ratios and guarantees long-term data sustainability and decodability through interoperability.

Fabian Müntefering
Yeremia Gunawan Adhisantoso
Jan Voges
ResearchOpen Access09 May 2024
Communications Biology

Volume: 7, P: 1-10
Comprehensive analysis of long-term trends, meteorological influences, and ozone formation sensitivity in the Jakarta Greater Area

Sheila Dewi Ayu Kusumaningtyas
Kenichi Tonokura
Nofi Azzah Rawaani Samputra
ResearchOpen Access26 Apr 2024
Scientific Reports

Volume: 14, P: 1-13
Techno-economic analysis of natural gas distribution using a small-scale liquefied natural gas carrier

Muhammad Arif Budiyanto
Gerry Liston Putra
Gerasimos Theotokatos
ResearchOpen Access21 Dec 2023
Scientific Reports

Volume: 13, P: 1-17
Selective inhibition of leukemia-associated SHP2^E69K mutant by the allosteric SHP2 inhibitor SHP099

X Sun
Y Ren
J Wu
Research30 Jan 2018
Leukemia

Volume: 32, P: 1246-1249
The Potential Value of Comparative Genomic Hybridization Analysis in Effusion—and Fine Needle Aspiration Cytology

Holger Nagel
Hans Jürgen Schulten
László Füzesi
Research01 Aug 2002
Modern Pathology

Volume: 15, P: 818-825
Site-dependent differential KIT and PDGFRA expression in gastric and intestinal gastrointestinal stromal tumors

Florian Haller
Nicole Happel
László Füzesi
Research03 Aug 2007
Modern Pathology

Volume: 20, P: 1103-1111
Epithelioid/mixed phenotype in gastrointestinal stromal tumors with KIT mutation from the stomach is associated with accelerated passage of late phases of the cell cycle and shorter disease-free survival

Florian Haller
Judith Cortis
Abbas Agaimy
Research10 Sept 2010
Modern Pathology

Volume: 24, P: 248-255
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance

Ottilie et al. employ an experimental evolution approach to investigate the role of transcription factors in yeast chemical resistance. Most emergent mutations in resistant strains were enriched in transcription factor coding genes, highlighting their importance in drug resistance.

Sabine Ottilie
Madeline R. Luth
Elizabeth A. Winzeler
ResearchOpen Access11 Feb 2022
Communications Biology

Volume: 5, P: 1-14
Bat-mouse bone marrow chimera: a novel animal model for dissecting the uniqueness of the bat immune system

Kylie Su Mei Yong
Justin Han Jia Ng
Lin-Fa Wang
ResearchOpen Access16 Mar 2018
Scientific Reports

Volume: 8, P: 1-10
Single-Crystalline Gold Nanowires Synthesized from Light-Driven Oriented Attachment and Plasmon-Mediated Self-Assembly of Gold Nanorods or Nanoparticles

Shang-Yang Yu
Hariyanto Gunawan
Jiunn-Woei Liaw
ResearchOpen Access16 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Novel flow cytometry approach to identify bronchial epithelial cells from healthy human airways

Danay Maestre-Batlle
Olga M. Pena
Chris Carlsten
ResearchOpen Access06 Feb 2017
Scientific Reports

Volume: 7, P: 1-9
A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice

Merry Gunawan
Zhisheng Her
Qingfeng Chen
ResearchOpen Access30 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor

Gregory M. Goldgof
Jacob D. Durrant
Elizabeth A. Winzeler
ResearchOpen Access13 Jun 2016
Scientific Reports

Volume: 6, P: 1-13
Low-coherence semiconductor light sources: devices and applications

Hang Lu
Omar Alkhazragi
Boon S. Ooi
ReviewsOpen Access03 Jun 2024
npj Nanophotonics

Volume: 1, P: 1-19
Drosophila caspase activity is required independently of apoptosis to produce active TNF/Eiger during nociceptive sensitization

Juyeon Jo
Seol Hee Im
Michael J Galko
ResearchOpen Access11 May 2017
Cell Death & Disease

Volume: 8, P: e2786

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