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The superconducting proximity effect has not been experimentally demonstrated in a quantum anomalous Hall insulator. Now this effect is observed in the chiral edge state of a ferromagnetic topological insulator.

Controlling emission and propagation of acoustic waves offers new design opportunities for acoustic devices. Here the authors demonstrate such controls thanks to the emergence of a synthetic pseudo-spin in two-dimensional acoustic metamaterial.

Applying magnetic and electric fields to twisted bilayer graphene creates an electron–hole bilayer that features helical 1D edge modes and fractional quantum Hall states.

Switching of magnetic behaviour is one of the main ideas that drives spintronics. Now, magnetic switching via spin-orbit torque is shown in a moiré bilayer, introducing a platform for spintronic applications.

Analysis of human Robertsonian chromosomes originating from 13, 14 and 21 reveal that they result from breaks at the SST1 macrosatellite DNA array and recombination between homologous sequences surrounding SST1.

Over 20 species of geographically and phylogenetically diverse bird species produce convergent whining vocalizations towards their respective brood parasites. Model presentation and playback experiments across multiple continents suggest that these learned calls provoke an innate response even among allopatric species.

Quantum Hall states are observed in monolayer graphene at even-denominator fractional filling of the lowest Landau level. This is linked to transitions in the spin and valley structure of the ground state.

Cryo-electron microscopy was used to study human mechanistic target of rapamycin complex 1 (mTORC1) activation on lysosomal membranes, showing progressive recruitment by RAG–Ragulator, RHEB and RAPTOR, culminating in mTOR–membrane engagement and full enzyme activation.

Inducing phase transitions in atomically thin films of layered materials requires efficient electrostatic doping techniques to reach high carrier densities. Here, the authors present a doping technique which induces superconductivity by reaching high n-doping density in few-layered MoS₂on glass substrates.

The extra states sometimes observed in graphene’s quantum Hall characteristics have been presumed to be the result of broken SU(4) symmetry. Magnetotransport measurements of high-quality graphene in a tilted magnetic field finally prove this is indeed the case.

Rhombohedral tetralayer graphene aligned to a hexagonal boron nitride substrate hosts gate-tunable superconductivity and quantized anomalous Hall states, and thermodynamic compressibility measurements further show a fractional Chern insulator at zero magnetic field, paving the way for new hybrid interfaces between superconductors and topological edge states.

A transient topological response in graphene is driven by a short pulse of light. When the Fermi energy is in the predicted band gap the Hall conductance is around two conductance quanta. An ultrafast detection technique enables the measurement.

Analysis of soundscape data from 139 globally distributed sites reveals that sounds of biological origin exhibit predictable rhythms depending on location and season, whereas sounds of anthropogenic origin are less predictable. Comparisons between paired urban–rural sites show that urban green spaces are noisier and dominated by sounds of technological origin.

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

We report both spin- and orbital-sourced Berry curvature in LaAlO₃/SrTiO₃ interfaces grown along the [111] direction.

Graphene systems exhibit flavor order transitions driven by tuning parameters. Here, the authors demonstrate an optical technique for detecting flavor textures in graphene via the exciton response of a proximal transition metal dichalcogenide layer.

Precise control of electrons in two-dimensional materials has been limited by fabrication techniques for local gates that introduce disorder. Now, a technique allows patterning of sub-100 nm features and fabrication of very clean interfaces.

Plasma proteomic analysis of presymptomatic individuals with amyotrophic lateral sclerosis identifies novel disease-associated proteins and enables the development of an accurate diagnostic biomarker panel.

The authors use spin waves to demonstrate that charged quantum Hall skyrmions exist away from integer filling. They also see evidence of several fractional skyrmion states.

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A nanoscale superconducting sensor used to map the magnetic fringe fields in twisted bilayers of MoTe₂ shows the formation of fractional Chern insulator states at zero magnetic field.

Helicity of photons is exploited for preferential emission direction and sorting of valley-polarized excitons is achieved at room temperature.

Smooth topological photonic interfaces lead to less localized boundary modes which improves their guiding characteristics in both spin- and valley Hall metasurfaces. The modes become insensitive to the lattice details, showcasing improved bandgap crossing and longer propagation distances.

The Haldane model is a paradigmatic example of topological behaviour but has not previously been implemented in condensed-matter experiments. Now a moiré bilayer is shown to realize this model with the accompanying quantized transport response.

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Over the last 15 years, the content of Nature Physics has covered an enormous breadth of subjects at the forefront of physics. The journal’s past and present editors recount their favourite papers and what made chaperoning them to publication special.

Itinerant magnetism in rhombohedral multilayer graphene shows a large excess entropy from magnetic fluctuations above its critical temperature—typically only associated with local moments—which implies the decoupling of charge and isospin degrees of freedom, and results in the isospin Pomeranchuk effect.

Various fractional quantum Hall phases are observed in a new generation of bilayer-graphene-based van der Waals heterostructures, including an even-denominator state predicted to harbour non-Abelian anyons.

Introducing spin–orbit coupling by substrate proximity effect leads to an enhancement of superconducting phases in rhombohedral trilayer graphene.

A study shows that rhombohedral graphene is an ideal platform for well-controlled tests of many-body theory and reveals that magnetism in moiré materials is fundamentally itinerant in nature.

An NNMT inhibitor reduces tumour burden and metastasis in multiple mouse cancer models and restores immune checkpoint blockade efficacy by decreasing cancer-associated-fibroblast-mediated recruitment of myeloid-derived suppressor cells and reinvigorating CD8⁺ T cell activation.

Topological order for sound remains largely unexplored. Here, Khanikaevet al. introduce the concept of topological order in classical acoustics, realizing robust topological protection and one-way edge propagation of sound in a suitably designed resonator lattice, thus expanding the ability to tailor acoustic waves.

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

An electronic analogue of the Pomeranchuk effect is present in twisted bilayer graphene, shown by the stability of entropy in a ferromagnetic phase compared to an unpolarized Fermi liquid phase at certain high temperatures.

Non-volatile electrical switching of magnetic order in an orbital Chern insulator is experimentally demonstrated using a moiré heterostructure and analysis shows that the effect is driven by topological edge states.

A lift-off and transfer method enables the fabrication of efficient three-dimensional racetrack memory devices fabricated from freestanding magnetic heterostructures on a prepatterned substrate and may—in the future—allow for advanced three-dimensional nanostructures in next-generation nanoelectronic devices with a low device footprint.

Forest restoration in LMICs can contribute to global C mitigation targets. Here, the authors assess the economic feasibility of forest restoration methods in Panama, i.e. natural regeneration, native species plantings, and enrichment planting, showing that not all methods are economically viable.

The role of electron–electron interactions in generating superconductivity in few-layer graphene remains controversial. Now, the observation of interaction-driven intervalley coherence may help to explain the Cooper pairing mechanism.

In this work light and matter have been coupled in a strong interaction between exciton resonances and topological photonic bands. The authors herein demonstrate a Z2 spin-Hall topological polaritonic phase enabling new coupling schemes in valleytronics and spintronics.

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

In twisted bilayer graphene, the moiré potential, strong electron–electron interactions and a magnetic field conspire to split the flat band into topologically non-trivial subbands.

The authors report ultrafast transport measurements on the photo-excited superconducting state in K₃C₆₀. They observe characteristic superconducting nonlinear current-voltage responses.

An initial draft of the human pangenome is presented and made publicly available by the Human Pangenome Reference Consortium; the draft contains 94 de novo haplotype assemblies from 47 ancestrally diverse individuals.