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Precise and scalable generation of high-quality NV centers is crucial for their integration into quantum devices. Here the authors demonstrate the high-yield controlled fabrication of highly coherent NV centers in prefabricated nanostructures with three-dimensional nanoscale spatial confinement, using a combination of δ-doping and focused electron beam irradiation.

Two-qubit operations exceeding 99% fidelity have been demonstrated by silicon devices made with standard semiconductor tooling in a 300-mm foundry environment.

Across qubit platforms, improving coherence often compromises operational speed. Here, the authors overcome this trade-off by electrically controlling a hole spin qubit in a Ge/Si core/shell nanowire, achieving triple manipulation speeds while quadrupling coherence times.

Systems of electron spins in nuclear-spin-rich hosts are gaining attention for quantum memory applications. Using spin ensemble studies, the authors propose transition metal ions in halide double perovskites as promising candidates, featuring long electron spin coherence and deterministic nuclear spin control.

A scalable architecture that is based on a quantum dot crossbar array comprising tightly pitched spin-qubit tiles and implemented in planar germanium, can be used characterize spin qubits.

Langstein-Skora, Schmid, Huth et al. propose that intrinsically disordered region functionality can be driven by the interplay between linear binding motifs and contextual chemical characteristics such as charge and hydrophobicity.

Spins confined to quantum dots are a possible qubit, but the mechanism that limits their coherence is unclear. Here, the authors use an all-optical Hahn-echo technique to determine the intrinsic coherence time of such spins set by its interaction with the inhomogeneously strained nuclear bath.

Conveyor-mode spin shuttling using a two-tone travelling-wave potential demonstrates an order of magnitude better spin coherence than bucket-brigade shuttling, achieving spin shuttling over 10 μm in under 200 ns with 99.5% fidelity in an isotopically purified Si/SiGe heterostructure.

The length of time a qubit can store information is linked to its coherence time. Here, the authors demonstrate that industrially important crystals comprising more than one species can host qubits with unexpectedly long coherence times.

Crohn’s disease is associated with disturbances in the B-cell compartment and secreted antibodies. Here, the authors reveal impaired colonic dimeric IgA responses in patients with Crohn’s disease and verify this phenotype in murine models, demonstrating that mitochondrial dysfunction drives defective mucosal humoral immunity.

Introgression of the short arm of rye chromosome one into common wheat increases root biomass and drought tolerance, but the underlying genetic basis is unknown. Here, the authors report that dosage differences in 12-OXOPHYTODIENOATE REDUCTASE genes modulate the differences of wheat root architecture.

An algorithm that combines deep learning, Bayesian optimization and computer vision techniques can be used to autonomously tune a semiconductor spin qubit from a grounded device to Rabi oscillations.

Trapped ions are promising for electrometry but limited by their weak intrinsic spin coupling to electric fields. Now it is shown that using a magnetic field gradient enhances sensitivity and enables precise measurements across subhertz to kilohertz frequencies.

Natural products populate areas of chemical space not occupied by average synthetic molecules. Here, an analysis of more than 180,000 natural product structures results in a library of 2,000 natural-product-derived fragments, which resemble the properties of the natural products themselves and give access to novel inhibitor chemotypes.

High sensitivity in quantum sensing comes often at the expense of other figures of merit, usually resulting in distortion. Here, the authors propose a protocol with good sensitivity, readout linearity and high frequency resolution, and benchmark it through signal measurements at audio bands with NV centers.

Quantum dot spin qubits in Si can be controlled using micromagnet-based electric-dipole spin resonance, but experiments have been limited to small 1D arrays. Here the authors address qubit control in 2D Si arrays, demonstrating low-frequency control of qubits in a 2 x 2 array using hopping gates.

Shallow NV centers in diamond are advantageous for quantum sensing but suffer from surface magnetic noise. Using first-principles simulations supported by experiments, the authors show that a combination of small magnetic fields and surface strain can significantly enhance spin coherence of 1 nm-deep NV centers.

Silicon-based spin qubits are promising candidates for a scalable quantum computer. Here the authors demonstrate the violation of Bell’s inequality in gate-defined quantum dots in silicon, marking a significant advancement that showcases the maturity of this platform.

Hole spin semiconductor qubits suffer from charge noise, but now it has been demonstrated that placing them in an appropriately oriented magnetic field can suppress this noise and improve qubit performance.

Optical spin defects in semiconductors are crucial for applications, but it is often difficult to establish their microscopic origin. A mechanism for the spin behaviour of a family of bright emitters in hexagonal boron nitride has now been identified.

Current applications of NV centers in diamond as spin-photon interfaces for quantum networks are limited by low coherent photon emission. Here, the authors integrate a coherently controlled NV spin qubit with an open microcavity to achieve Purcell-enhanced emission and demonstrate spin-photon state generation.

Quantum coherence is hard to maintain in solid-state systems, as interactions usually lead to fast dephasing. Exploiting disorder effects and interactions, highly coherent two-level systems have now been realized in a rare-earth insulator compound.

Plant traits drive ecosystem dynamics yet are challenging to map globally due to sparse measurements. Here, the authors combine crowdsourced biodiversity observations with Earth observation data to accurately map 31 plant traits at 1 km² resolution.

The detection and coherent control of single ¹³C nuclear spins in hexagonal boron nitride at room temperature enables the use of van der Waals materials in upcoming quantum technologies.

Juvenile idiopathic arthritis (JIA) associated uveitis can cause vision loss in children, but mechanisms remain unclear. The authors here identify elevated CD19⁺IgD^-CD27^- double negative type 1 B cells in JIA-uveitis and show that targeting B-T cell interactions suppresses disease in mouse models of uveitis.

Operation sweet spots decouple hole spin qubits in silicon from charge noise while conserving full electrical control and allowing for spin coherence times of up to 88 μs.

The coherent operation of individual ³¹P electron and nuclear spin qubits in a ²⁸Si substrate shows new benchmark decoherence times and provides essential information on the dechorence mechanism.

Hybrid systems composed of defect centres in diamond and mechanical resonators are promising for studies in quantum information science and optomechanics. Here, the authors show direct coupling of the spin of a nitrogen–vacancy centre to a diamond cantilever through lattice strain.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

In targeted protein degradation, a degrader molecule brings a neosubstrate protein proximal to a hijacked E3 ligase for its ubiquitination. Here, pseudo-natural products derived from (−)-myrtanol—iDegs—are identified to inhibit and induce degradation of the immunomodulatory enzyme indoleamine-2,3-dioxygenase 1 (IDO1) by a distinct mechanism. iDegs prime apo-IDO1 ubiquitination and subsequent degradation using its native proteolytic pathway.

Initialization and operation of spin qubits in silicon above 1 K reach fidelities sufficient for fault-tolerant operations at these temperatures.

An optically addressable fluorescent-protein spin qubit is realized using enhanced yellow fluorescent protein; the qubit can be coherently controlled at liquid-nitrogen temperatures and the spin detected at room temperature in cells.

Isotope engineering of silicon carbide leads to control of nuclear spins associated with single divacancy centres and extended electron spin coherence.

Despite looking highly irregular, most real-world networks exhibit natural stability to external perturbations. A study of the properties of the stability matrix of networks now sheds light on the principles underlying this emerging stability.

A materials platform using tantalum as a base layer and silicon as the substrate to construct superconducting qubits enables device performance improvements such as millisecond lifetimes and coherence times, as well as high time-averaged quality factors.

Solid-state systems are established candidates to study models of many-body physics but have limited control and readout capabilities. Ensembles of defects in diamond may provide a solution for studying dipolar systems.

Karposi’s Sarcoma-associated herpesvirus (KSHV) infection is associated with malignancy in older infected humans. Here the authors characterise antigen presentation using a KSHV-specific CD4⁺ T cell-derived TCR in a mouse model and show that although KSHV-specific CD4⁺ T cells are difficult to detect in humans, antigen presentation is effective in vivo suggesting persistence and accumulation of these cells through antigen recognition.

Quantum computing requires fast and selective control of a large number of individual qubits while maintaining coherence, which is hard to achieve concomitantly. All-electrical operation of a hole spin qubit in a Ge/Si nanowire demonstrates the principle of switching from a mode of selective and fast control to idling with increased coherence.

This work challenges the view of nucleation governing halide perovskite grain morphology, showing that most additives act post-nucleation by boosting ion mobility across grain boundaries, triggering grain coarsening, similar to post-processing effects.

A technique to study the noise in quantum systems has been devised by using spectral filters in reverse. So-called dynamical-decoupling pulse sequences, previously used to remove noise, now quantify how a superconducting qubit interacts with its noisy environment.

Spin qubits in systems with strong spin–orbit coupling can be electrically controlled, but are usually affected by short coherence times. Here, coherence times up to 10 ms are obtained for strain-engineered hole states bound to boron acceptors in silicon 28.