Epstein-Barr virus (EBV) infects B cells, and has been linked to tumorigenesis and autoimmunity. Here the authors show, using in vitro culture and mouse models, that EBV infection alters B cell FAK signaling to induces aberrant proliferation, migration and diapedesis, thereby serving potential mechanism for EBV-induced, B cell-related pathology.
- Susanne Delecluse
- Francesco Baccianti
- Henri-Jacques Delecluse
