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Showing 1–50 of 789 results

Advanced filters: Author: D Steele Clear advanced filters

Folding-mediated secretion of pure bispecific antibodies

Mutation of conserved prolines enhances correct pairing of light and heavy chains for bispecific IgG-like antibody production.

Cholpon Tilegenova
Tun Liu
Adam Zwolak
Research07 Oct 2025
Nature Biotechnology

P: 1-9
Redox-driven mineral and organic associations in Jezero Crater, Mars

A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and organic signatures that warrant consideration as potential biosignatures.

Joel A. Hurowitz
M. M. Tice
Z. U. Wolf
ResearchOpen Access10 Sept 2025
Nature

Volume: 645, P: 332-340
Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms

Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis involving evasion of immune control. Here, the authors perform a comprehensive analysis of single-cell multi-omic data revealing either a myeloid-enriched or adaptive-enriched tumour microenvironment, linked to distinct B and T cell clonal selection and differentiation, distinct overall survival, and potential therapeutic approaches.

Shivan Sivakumar
Ashwin Jainarayanan
Rachael Bashford-Rogers
ResearchOpen Access06 Feb 2025
Nature Communications

Volume: 16, P: 1-20
Mechanism of Action of Insulin

A. DUNN
N. ALTSZULER
J. S. BISHOP
Research18 Apr 1959
Nature

Volume: 183, P: 1123-1124
Evidence for polycyclic aromatic hydrocarbons detected in sulfates at Jezero crater by the Perseverance rover

The Perseverance rover detected polycyclic aromatic hydrocarbons preserved within sulfates in the fan and floor of Jezero crater on Mars, offering new insights into past habitability and the preservation of organic matter on Mars.

Teresa Fornaro
Sunanda Sharma
Amy J. Williams
Research04 Sept 2025
Nature Astronomy

P: 1-14
An Effect of Insulin on Production of Glucose during Hepatic Glycogenolysis

A. DUNN
R. C. de BODO
D. T. ARMSTRONG
Research15 Oct 1960
Nature

Volume: 188, P: 236-237
A Theory of Fuel-Knock

SYDNEY STEELE
Research20 May 1933
Nature

Volume: 131, P: 724-725
Pectic Polysaccharides in the Growth of Plant Cells: Molecular Structural Factors and Their Role in the Germination of White Mustard

SHEILA E. B. GOULD
D. A. REES
I. W. STEELE
Research27 Nov 1965
Nature

Volume: 208, P: 876-878
The mutagenic forces shaping the genomes of lung cancer in never smokers

An analysis of data from the Sherlock-Lung study provides insight into the mutational processes that contribute to lung cancer in never smokers, and looks at the possible role of factors such as air pollution and passive smoking.

Marcos Díaz-Gay
Tongwu Zhang
Maria Teresa Landi
Research02 Jul 2025
Nature

Volume: 644, P: 133-144
Glucagon-like immunoreactivity in insect corpus cardiacum

H. S. TAGER
J. MARKESE
K. J. KRAMER
Research24 Apr 1975
Nature

Volume: 254, P: 707-708
Antarctic ice volume and contribution to sea-level fall at 20,000 yr BP from raised beaches

E. A. Colhoun
M. C. G. Mabin
R. M. Kirk
Research23 Jul 1992
Nature

Volume: 358, P: 316-319
Combination with Red Cells of Immune Rabbit 7S Antibody and its Sub-Units

C. L. GREENBURY
D. H. MOORE
L. A. C. NUNN
Research12 Sept 1964
Nature

Volume: 203, P: 1147-1148
Biosynthetic Labelling of Mammalian Insulins in vitro

K. W. TAYLOR
D. G. PARRY
G. HOWARD SMITH
Research12 Sept 1964
Nature

Volume: 203, P: 1144-1145
A charge-decoration technique for studying the heterogeneity of coexistent monolayer phases by electron microscopy

A. Fischer
E. Sackmann
Research24 Jan 1985
Nature

Volume: 313, P: 299-301
Generation of large amplitude phonon states in quantum acoustics

Quantum acoustics investigates the interaction between mechanical oscillators and superconducting qubits. Here, the authors demonstrate the generation of large-amplitude phonon states using quantum acoustics’ toolbox.

Clinton A. Potts
Wilfred J. M. Franse
Gary A. Steele
ResearchOpen Access02 Jul 2025
Nature Communications

Volume: 16, P: 1-6
Boron cosmochemistry interpreted from abundances in mantle xenoliths

Michael D. Higgins
Denis M. Shaw
Research08 Mar 1984
Nature

Volume: 308, P: 172-173
Loss of colonic fidelity enables multilineage plasticity and metastasis

The chromatin-remodelling enzyme ATRX and the transcription factor HNF4A are identified as pivotal regulators of colonic epithelial identity, with roles in metastasis in colorectal cancer.

Patrizia Cammareri
Michela Raponi
Kevin B. Myant
ResearchOpen Access04 Jun 2025
Nature

Volume: 644, P: 547-556
The correction of post-keratoplasty astigmatism

N C Price
A D McG Steele
Research01 Sept 1987
Eye

Volume: 1, P: 562-566
Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy

Subramanian et al. use the EcoTyper machine-learning framework to characterize the tumor, immune and stromal cell states and ecosystems that comprise sarcomas.

Ajay Subramanian
Neda Nemat-Gorgani
Everett J. Moding
Research01 Mar 2024
Nature Cancer

Volume: 5, P: 642-658
The Anatomy of Frustration

A. D. HALL
Books & Arts07 Nov 1936
Nature

Volume: 138, P: 779-780
New Pathways in the Oxidative Metabolism of Aromatic Compounds by Micro-Organisms

S. DAGLEY
W. CHARLES EVANS
D. W. RIBBONS
Research12 Nov 1960
Nature

Volume: 188, P: 560-566
An Enzyme for the Metabolic Control of Polysaccharide Conformation and Function

C. J. LAWSON
D. A. REES
Research25 Jul 1970
Nature

Volume: 227, P: 392-393
Pitcairn Island—another Pacific hot spot?

R. A. Duncan
I. McDougall
D. S. Coombs
Research25 Oct 1974
Nature

Volume: 251, P: 679-682
Heterogeneity of Water-Soluble Structural Components of Human Red Cell Membrane

M. D. POULIK
P. K. LAUF
Research27 Nov 1965
Nature

Volume: 208, P: 874-876
A highly mobile Laurentide ice sheet revealed by satellite images of glacial lineations

G. S. Boulton
C. D. Clark
Research30 Aug 1990
Nature

Volume: 346, P: 813-817
Directed Genetic Change Model for X Chromosome Inactivation in Eutherian Mammals

D. W. COOPER
Research02 Apr 1971
Nature

Volume: 230, P: 292-294
Preliminary Experiments on the Chemistry and Pharmacology of Cannabis

E. W. GILL
W. D. M. PATON
R. G. PERTWEE
Research10 Oct 1970
Nature

Volume: 228, P: 134-136
Chemical uniformity of airborne particulate material, and a maritime effect

D. H. Peirson
P. A. Cawse
R. S. Cambray
Research25 Oct 1974
Nature

Volume: 251, P: 675-679
Geographic and age variations in mutational processes in colorectal cancer

Analysis of genomic data from 981 colorectal cancers from participants in 11 countries reveals variations in mutational signatures of microsatellite-stable cancers that are dependent on geographical origin and age at which the cancer was diagnosed.

Marcos Díaz-Gay
Wellington dos Santos
Ludmil B. Alexandrov
ResearchOpen Access23 Apr 2025
Nature

Volume: 643, P: 230-240
Local paracrine effects of estradiol are central to parturition in the rhesus monkey

Peter W. Nathanielsz
Susan L. Jenkins
Dino A. Giussani
Research01 Apr 1998
Nature Medicine

Volume: 4, P: 456-459
A Wilson Cloud Chamber with Time-Marking of Particle Tracks

D. GABOR
B. HAMPTON
Research12 Oct 1957
Nature

Volume: 180, P: 746-749
Metabolism of 3-Hydroxyanthranilic Acid labelled with Carbon-14 Carboxyl in Normal and Neoplastic Mice

LAWRENCE V. HANKES
M. SCHMAELER
RICHARD D. STONER
Research16 Nov 1963
Nature

Volume: 200, P: 676-677
Mitotic stability of fragile X mutations in differentiated cells indicates early post–conceptional trinucleotide repeat expansion

Doris Wöhrle
Ingeborg Hennig
Peter Steinbach
Research01 Jun 1993
Nature Genetics

Volume: 4, P: 140-142
Effect of Oxygen and Nitric Oxide on the Radiosensitivity of Human Cells in Tissue Culture

D. L. DEWEY
Research04 Jun 1960
Nature

Volume: 186, P: 780-782
Synthesis of Serine by Micro-organisms

JUNE LASCELLES
D. D. WOODS
Research14 Oct 1950
Nature

Volume: 166, P: 649-650
The smfBox is an open-source platform for single-molecule FRET

Broad uptake of smFRET has been hindered by high instrument costs and a lack of open-source hardware and acquisition software. Here, the authors present the smfBox, a cost-effective open-source platform capable of measuring precise FRET efficiencies between dyes on freely diffusing single molecules.

Benjamin Ambrose
James M. Baxter
Timothy D. Craggs
ResearchOpen Access06 Nov 2020
Nature Communications

Volume: 11, P: 1-6
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

Phenotypic and functional heterogeneity of cancer associated fibroblasts (CAFs) has been reported in pancreatic ductal adenocarcinoma (PDAC). Here the authors show that epithelial MAPK activity promotes myofibroblastic differentiation of CAFs. Furthermore, the epithelial basal-like subtype is associated with a CAF phenotype characterized by elevated MAPK activity and TGF-β signalling, associated with T cell exclusion in PDAC.

Lisa Veghini
Davide Pasini
Vincenzo Corbo
ResearchOpen Access03 Dec 2024
Nature Communications

Volume: 15, P: 1-20
Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer

There is high prevalence of whole genome duplication (WGD) in high grade serous ovarian cancer. Here, the authors compare tumours with and without WGD and find that those that acquired WGD early during tumour evolution are associated with worse survival and have the lowest expression of MHC-II.

Nikki L. Burdett
Madelynne O. Willis
Elizabeth L. Christie
ResearchOpen Access18 Jul 2024
Nature Communications

Volume: 15, P: 1-13
Penetrating keratoplasty and cataract surgery: The advantages of an extracapsular technique combined with posterior chamber intraocular implantation

C M Kirkness
P Y Y Cheong
A D McG Steele
Research01 Sept 1987
Eye

Volume: 1, P: 557-561
⁴⁰Ar/³⁹Ar age limit for an Acheulian site in Israel

G. Feraud
D. York
H. P. Schwarcz
Research21 Jul 1983
Nature

Volume: 304, P: 263-265
The role of penetrating keratoplasty in the management of microbial keratitis

Colin M Kirkness
Linda A Ficker
Noel S C Rice
Research01 Jul 1991
Eye

Volume: 5, P: 425-431
Mitotic tethering enables inheritance of shattered micronuclear chromosomes

Chromothriptically produced pieces of a micronucleated chromosome are shown to be tethered together in mitosis by a protein complex consisting of MDC1, TOPBP1 and CIP2A, thus enabling their inheritance by a single daughter cell.

Prasad Trivedi
Christopher D. Steele
Don W. Cleveland
Research14 Jun 2023
Nature

Volume: 618, P: 1049-1056
A comparison of patient survival and tumour growth kinetics in human bronchogenic carcinoma

KM Kerr
D Lamb
Research01 Oct 1988
British Journal of Cancer

Volume: 58, P: 419-422
Basal Hot Spot on a Surge Type Glacier

D. F. CLASSEN
G. K. C. CLARKE
Research12 Feb 1971
Nature

Volume: 229, P: 481-483
Intraocular surgery following penetrating keratoplasty: The risks and advantages

L A Ficker
C M Kirkness
A M E Gilvarry
Research01 Sept 1990
Eye

Volume: 4, P: 693-697
Identifying signatures of photothermal current in a double-gated semiconducting nanotube

Semiconducting carbon nanotubes have already demonstrated their potential for solar-cell and photodetector applications. Here, the authors use scanning photocurrent microscopy to show that the photocurrent generated in such nanotubes can be dominated by both photovoltaic and photothermal mechanisms.

G. Buchs
S. Bagiante
G. A. Steele
Research19 Sept 2014
Nature Communications

Volume: 5, P: 1-6
Identification of a common oncofoetal protein in x-ray and chemically induced rat gastrointestinal tumours

R H Stevens
D A Cole
H F Cheng
Research01 Jun 1981
British Journal of Cancer

Volume: 43, P: 817-825
Adult haematopoietic cells transplanted to sheep fetuses continue to produce adult globins

Esmail D. Zanjani
Giat Lim
George Stamatoyannopoulos
Research21 Jan 1982
Nature

Volume: 295, P: 244-246
Action of Insulin on the Isolated Rat Diaphragm in the Presence of Actinomycin D and Puromycin

D. EBOUÉ-BONIS
A. M. CHAMBAUT
H. CLAUSER
Research21 Sept 1963
Nature

Volume: 199, P: 1183-1184
ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

D. DeFeo-Jones
E. M. Scolnick
R. Dhar
Research15 Dec 1983
Nature

Volume: 306, P: 707-709

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