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Showing 101–150 of 900 results

Advanced filters: Author: D Winkler Clear advanced filters

Increased Urinary Pseudouridine Excretion in Rats following Irradiation

D. DRAHOVSKÝ
A. WINKLER
J. ŠKODA
Research25 Jan 1964
Nature

Volume: 201, P: 411-412
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

Akhteruzzaman Molla
Marina Korneyeva
Dale J. Kempf
Research01 Jul 1996
Nature Medicine

Volume: 2, P: 760-766
Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington’s disease

Microglia mediate the early and selective degeneration of corticostriatal synapses and the development of cognitive deficits in presymptomatic Huntington’s disease via the complement cascade.

Daniel K. Wilton
Kevin Mastro
Beth Stevens
ResearchOpen Access09 Oct 2023
Nature Medicine

Volume: 29, P: 2866-2884
Simultaneous rift-scale inflation of a deep crustal sill network in Afar, East Africa

This study shows that magma rising from deep in the Earth’s mantle is not a continuous process but occurs in episodes. This is observed in East Africa with simultaneously replenishing of four magma pockets.

A. La Rosa
C. Pagli
D. Keir
ResearchOpen Access20 May 2024
Nature Communications

Volume: 15, P: 1-8
Bat genomes illuminate adaptations to viral tolerance and disease resistance

A systematic analysis of 115 mammalian genomes, including 10 new bat genomes, reveals prevalent positive selection in immune genes in bats and shows key adaptations in the antiviral gene ISG15 that aid disease resistance in bats, including to coronaviruses.

Ariadna E. Morales
Yue Dong
Michael Hiller
ResearchOpen Access29 Jan 2025
Nature

Volume: 638, P: 449-458
Variation in auxin sensing guides AUX/IAA transcriptional repressor ubiquitylation and destruction

The phytohormone auxin is sensed by SCF^TIR1-AUX/IAA receptors leading to AUX/IAA repressor ubiquitylation and turnover. Here the authors show that IAA6 and IAA19 differ in their ubiquitylation and turnover dynamics, differentially contributing to auxin sensing and enabling discrimination of auxin concentrations.

Martin Winkler
Michael Niemeyer
Luz Irina A. Calderón Villalobos
ResearchOpen Access07 Jun 2017
Nature Communications

Volume: 8, P: 1-13
Cirrus-cloud thermostat for tropical sea surface temperatures tested using satellite data

Rong Fu
Anthony D. Del Genio
W. Timothy Liu
Research30 Jul 1992
Nature

Volume: 358, P: 394
Structure of mitochondrial creatine kinase

Karin Fritz-Wolf
Thomas Schnyder
Wolfgang Kabsch
Research23 May 1996
Nature

Volume: 381, P: 341-345
The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

David W. Banner
Allan D'Arcy
Daniel Kirchhofer
Research07 Mar 1996
Nature

Volume: 380, P: 41-46
Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

D. C. Wiley
I. A. Wilson
J. J. Skehel
Research29 Jan 1981
Nature

Volume: 289, P: 373-378
Unequal access to social, environmental and health amenities in US urban parks

Parks provide deep value to urban residents, but the distribution of those services is unclear. This study finds that US urban residents have unequal access to the crucial environmental, social and health amenities of urban parks.

Richelle L. Winkler
Jeffrey A. G. Clark
Christopher A. Lepczyk
Research08 Nov 2024
Nature Cities

Volume: 1, P: 861-870
A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications

In GWAS, waist-to-hip ratio (WHR) is often adjusted for body mass index (BMI) to account for their correlation (WHRadjBMI). Here, Winkler et al. classify 159 genetic variants for BMI, WHR, or WHRadjBMI based on their effect directions for BMI and WHR to differentiate subtypes of adiposity genetics.

Thomas W Winkler
Felix Günther
Iris M Heid
ResearchOpen Access16 May 2018
Nature Communications

Volume: 9, P: 1-13
Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1⁺CD8⁺ T cells

Here the authors dissect the contribution of IL-21 signaling to immune checkpoint-responding CD8⁺ T cells from mouse models and patients being treated for advanced melanoma.

Zhen Zhang
Marlene Langenbach
Bertram Bengsch
Research19 Dec 2024
Nature Immunology

Volume: 26, P: 92-104
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Heart failure is a complex syndrome that is associated with many different underlying risk factors. Here, to increase power, the authors jointly analyse cases of heart failure of different aetiologies in a genome-wide association study and identify 11 loci of which ten had not been previously reported.

Sonia Shah
Albert Henry
R. Thomas Lumbers
ResearchOpen Access09 Jan 2020
Nature Communications

Volume: 11, P: 1-12
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

I. A. Wilson
J. J. Skehel
D. C. Wiley
Research29 Jan 1981
Nature

Volume: 289, P: 366-373
Erratum: Sequential late Cenozoic structural disruption of the northern Himalayan foredeep

D. W. Burbank
R. G. H. Raynolds
Research18 Oct 1984
Nature

Volume: 311, P: 680
Effect of Antilymphocyte Serum on the Survival of Ovary Allografts in the Mouse

A. D. BARNES
C. CROSIER
Research06 Sept 1969
Nature

Volume: 223, P: 1059-1060
Atlantic-origin water extension into the Pacific Arctic induced an anomalous biogeochemical event

The authors show that the appearance of anomalously low oxygen and acidified water on the Chukchi Plateau, a high-seas fishable area of the western Arctic Ocean, is associated with a change in basin-scale ocean circulation related to the recent sea ice loss.

Shigeto Nishino
Jinyoung Jung
Sung-Ho Kang
ResearchOpen Access02 Nov 2023
Nature Communications

Volume: 14, P: 1-12
Low oxygen eddies in the eastern tropical North Atlantic: Implications for N₂O cycling

D. S. Grundle
C. R. Löscher
B. Fiedler
ResearchOpen Access06 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
Endothelial-secreted Endocan activates PDGFRA and regulates vascularity and spatial phenotype in glioblastoma

Glioblastoma (GBM) is rich in tumor-associated vasculature and it remains to be understood how GBM is supported by vascular endothelial cells. Here, the authors identify that endothelial-secreted proteoglycan endocan acts as a ligand of PDGFR alpha receptor to promote GBM progression and induce therapy resistance.

Soniya Bastola
Marat S. Pavlyukov
Harley I. Kornblum
ResearchOpen Access07 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Reversal of Penicillin Inhibition by a Yeast Extract

F. W. CHATTAWAY
D. A. HALL
E. S. HOLDSWORTH
Research20 Aug 1949
Nature

Volume: 164, P: 314-315
Models for the origin of influenza viruses

I. M. HENDERSON
DAVID PENNY
MICHAEL D. HENDY
Research01 Mar 1987
Nature

Volume: 326, P: 22
Network topology and entropy analysis of tetragonal farneseite zeolites

Kavin Jacob
Joseph Clement
Krishnan Balasubramanian
ResearchOpen Access28 Apr 2025
Scientific Reports

Volume: 15, P: 1-14
Quasar enhanced

S. K. ALURKAR
A. K. SHARMA
R. V. BHONSLE
Research16 Mar 1989
Nature

Volume: 338, P: 211-212
Light-dependent modulation of protein localization and function in living bacteria cells

Bacterial proteins are often recruited to specific subcellular locations to carry out their functions. Here, the authors use the optogenetic CRY2-CIB1 system to re-direct proteins to different subcellular locations, and thus manipulate the proteins’ functions, in live bacterial cells.

Ryan McQuillen
Amilcar J. Perez
Jie Xiao
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-15
Massive deep-sea sulphide ore deposits discovered on the East Pacific Rise

J. Francheteau
H. D. Needham
R. Hekinian
Research01 Feb 1979
Nature

Volume: 277, P: 523-528
A Method for Determining the Ratio of the Michael is Constants of an Enzyme with Respect to Two Substrates

V. P. WHITTAKER
D. H. ADAMS
Research20 Aug 1949
Nature

Volume: 164, P: 315-316
Hydrographic Observations of the Red Sea Brines

R. G. MUNNS
R. J. STANLEY
C. D. DENSMORE
Research17 Jun 1967
Nature

Volume: 214, P: 1215-1217
Evolution of the Tasman Sea

J. G. JONES
W. D. ROOTS
Research13 Dec 1974
Nature

Volume: 252, P: 613-614
Simultaneous radio scattering and white light observations of a coronal transient

Richard Woo
J. W. Armstrong
M. J. Koomen
Research11 Nov 1982
Nature

Volume: 300, P: 157-159
GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

Winkler et al. show that the glucose transporter GLUT1 in brain endothelium is necessary for the maintenance of proper brain capillary networks and blood-brain barrier integrity. The study also shows that loss of GLUT1 in a mouse model of Alzheimer's disease accelerates BBB breakdown, perfusion and metabolic stress resulting in behavioral deficits, elevated amyloid beta levels and neurodegeneration.

Ethan A Winkler
Yoichiro Nishida
Berislav V Zlokovic
Research02 Mar 2015
Nature Neuroscience

Volume: 18, P: 521-530
A cosmogenic ¹⁰Be anomaly during the late Miocene as independent time marker for marine archives

Several Pacific deep-ocean ferromanganese crusts record an anomalous increase of the cosmogenic radionuclide ¹⁰Be around 10.1 Ma. This anomaly is a potential independent time marker for the late Miocene.

Dominik Koll
Johannes Lachner
Anton Wallner
ResearchOpen Access10 Feb 2025
Nature Communications

Volume: 16, P: 1-9
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

An increase in the volume of the brain lateral ventricles is a sign of normal aging, but can also be associated with neurological and psychiatric disorders. Here, Vojinovic et al. identify seven genetic loci in a GWA study for ventricular volume in 23,500 individuals and find correlation with thalamus volume.

Dina Vojinovic
Hieab H. Adams
Myriam Fornage
ResearchOpen Access26 Sept 2018
Nature Communications

Volume: 9, P: 1-11
Airborne Transmission of Influenza Virus Infection in Mice

JEROME L. SCHULMAN
EDWIN D. KILBOURNE
Research15 Sept 1962
Nature

Volume: 195, P: 1129-1130
Phoretic Association between Afronurus and Simulium Species, and the Discovery of the Early Stages of Simulium neavei on Freshwater Crabs

VERNON D. VAN SOMEREN
J. McMAHON
Research26 Aug 1950
Nature

Volume: 166, P: 350-351
Quasar enhanced

S. ANANTHAKRISHNAN
P. K. MANOHARAN
R. V. VENUGOPAL
Research16 Mar 1989
Nature

Volume: 338, P: 212
Production of Vibrationally Excited Oxygen Molecules in the Flash Photolysis of Ozone

W. D. McGRATH
R. G. W. NORRISH
Research07 Dec 1957
Nature

Volume: 180, P: 1272-1273
Effect of Extracts from the Urine of Schizophrenic Patients on the Evoked Cortical Response in the Rat

G. A. GERMAN
D. KEMALI
Research25 May 1963
Nature

Volume: 198, P: 791-792
New Approach to Experiments on Low Intensity Interference

D. N. PINDER
R. N. GOULD
Research01 Feb 1969
Nature

Volume: 221, P: 460-461
Convergent evolution in Afrotheria and non-afrotherians demonstrates high evolvability of the mammalian inner ear

The inner ear is responsible for hearing and balance control. Here, the authors examine evolutionary convergence in the inner ear morphology of Afrotheria species and similar, non-Afrotheria analogue species, finding unexpectedly high evolvability.

Nicole D. S. Grunstra
Fabian Hollinetz
Anne Le Maître
ResearchOpen Access16 Sept 2024
Nature Communications

Volume: 15, P: 1-13
Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue

Intestinal homeostasis is maintained by interactions between the gut-associated lymphoid tissue and the resident flora. Here Montorsi et al use multiplexed single cell omics to describe double negative type 2 B cells and DNASE1L3-expressing dendritic cells that interact and associate with microbiota on the human gut antigenic front line.

Lucia Montorsi
Michael J. Pitcher
Jo Spencer
ResearchOpen Access14 May 2024
Nature Communications

Volume: 15, P: 1-17
Crystallographic structure and functional implications of the nitrogenase molybdenum–iron protein from Azotobacter vinelandii

Jongsun Kirn
D. C. Rees
Research10 Dec 1992
Nature

Volume: 360, P: 553-560
Synthesis of Serine by Micro-organisms

JUNE LASCELLES
D. D. WOODS
Research14 Oct 1950
Nature

Volume: 166, P: 649-650
Method for Proton Irradiation of Rats

L. D. ENGLAND
Research01 Dec 1966
Nature

Volume: 212, P: 1596-1597
Species and Sex-specific Compounds from the Heads of Male Bumblebees (Bombus spp.)

D. H. CALAM
Research01 Mar 1969
Nature

Volume: 221, P: 856-857
Fifty years of limnological data on Lake Stechlin, a temperate clearwater lake

Sabine Wollrab
Silke R. Schmidt
Rainer Koschel
ResearchOpen Access18 Jun 2025
Scientific Data

Volume: 12, P: 1-10
Uranium in Recent Japanese Sediments

YUKIO SUGIMURA
TOSHIKO SUGIMURA
Research12 May 1962
Nature

Volume: 194, P: 568-569
Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

Frank D. McKeon
Marc W. Kirschner
Daniel Caput
Research06 Feb 1986
Nature

Volume: 319, P: 463-468
Evidence for the direct involvement of DNA replication origin in synthesis of late SV40 RNA

R. Contreras
D. Gheysen
W. Fiers
Research09 Dec 1982
Nature

Volume: 300, P: 500-505
Prediction of creatinine clearance from serum creatinine in spinal cord injury patients

M K Mirahmadi
C Byrne
N D Vaziri
Research01 Feb 1983
Spinal Cord

Volume: 21, P: 23-29

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