Nature Search

Lack of SMARCB1 expression characterizes a subset of human and murine peripheral T-cell lymphomas

Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous and aggressive type of T-cell lymphoma. Here, the authors perform single-cell analyses of human and murine PTCL-NOS tumors, and identify a subtype defined by the loss of SMARCB1 that could be targeted with HDAC-inhibitor combination therapies.

Anja Fischer
Thomas K. Albert
Kornelius Kerl
ResearchOpen Access03 Oct 2024
Nature Communications

Volume: 15, P: 1-18
Observation of charge–parity symmetry breaking in baryon decays

The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.

R. Aaij
A. S. W. Abdelmotteleb
G. Zunica
ResearchOpen Access16 Jul 2025
Nature

Volume: 643, P: 1223-1228
Fine-mapping genomic loci refines bipolar disorder risk genes

This study used fine-mapping to analyze genetic regions associated with bipolar disorder, identifying specific risk genes and providing new insights into the biology of the condition that may guide future research and treatment approaches.

Maria Koromina
Ashvin Ravi
Niamh Mullins
ResearchOpen Access25 Jun 2025
Nature Neuroscience

Volume: 28, P: 1393-1403
Aging drives cerebrovascular network remodeling and functional changes in the mouse brain

We have limited knowledge of how aging affects brain vascular structure and function. Here, the authors show that aging induces selective reduction of vasculature and related cell types in key cognitive brain areas and reduces blood oxygenation.

Hannah C. Bennett
Qingguang Zhang
Yongsoo Kim
ResearchOpen Access30 Jul 2024
Nature Communications

Volume: 15, P: 1-20
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE

SLE is a heterogeneous disorder that is characterized by different immune endotypes. Faliti et al. follow the immune memory responses upon mRNA COVID-19 vaccinations in a large cohort of patients with SLE. They note that skewed immune responses, such as lower seroconversion and neutralization, might be due to extrafollicular B and T cell biases in SLE endotypes.

Caterina E. Faliti
Trinh T. P. Van
Ignacio Sanz
ResearchOpen Access12 Nov 2024
Nature Immunology

Volume: 26, P: 131-145
Genomics yields biological and phenotypic insights into bipolar disorder

Using multi-ancestry genome-wide association study and fine-mapping, 298 loci and 36 credible genes are identified in the aetiology of bipolar disorder.

Kevin S. O’Connell
Maria Koromina
Dan Siskind
Research22 Jan 2025
Nature

Volume: 639, P: 968-975
Scalable spin–photon entanglement by time-to-polarization conversion

Rui Vasconcelos
Sarah Reisenbauer
Michael Trupke
ResearchOpen Access28 Jan 2020
npj Quantum Information

Volume: 6, P: 1-5
A map of the rubisco biochemical landscape

A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO₂ affinity are possible, signposting further enzyme engineering efforts to increase crop yields.

Noam Prywes
Naiya R. Phillips
David F. Savage
ResearchOpen Access22 Jan 2025
Nature

Volume: 638, P: 823-828
Diversity begets diversity in competition for space

Sessile communities may support high species richness, despite competition for space. Here, the authors use fungal competition assays to show that intransitive competition can overwhelm pairwise competitive exclusion to facilitate biodiversity.

Daniel S. Maynard
Mark A. Bradford
Thomas W. Crowther
Research15 May 2017
Nature Ecology & Evolution

Volume: 1, P: 1-8
The 2018 European heatwave led to stem dehydration but not to consistent growth reductions in forests

Forest dynamics are monitored at large scales with remote sensing, but individual tree data are necessary for ground-truthing and mechanistic insights. This study on high temporal resolution dendrometer data across Europe reveals that the 2018 heatwave affected tree physiology and growth in unexpected way.

Roberto L. Salomón
Richard L. Peters
Kathy Steppe
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-11
Consistent trade-offs in fungal trait expression across broad spatial scales

A trait-based approach used to quantify the niches of 23 species of saprotrophic wood decomposer fungi collected throughout North America provides preliminary insight into the linkages among functional trait expression, climate and phylogeny.

Daniel S. Maynard
Mark A. Bradford
Thomas W. Crowther
Research25 Feb 2019
Nature Microbiology

Volume: 4, P: 846-853
Synergistic effect of MDM2 inhibitors and radiotherapy in endometrial cancer

Roberto Vargas
Aaron Petty
Jacob Scott
ResearchOpen Access18 Aug 2025
npj Precision Oncology

Volume: 9, P: 1-9
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation

Poeck and colleagues identify a microbiome signature in patients receiving allogenic stem cell transplantation, which is associated with protective immune-modulatory metabolites, improved survival and less transplant-related mortality.

Erik Thiele Orberg
Elisabeth Meedt
Hendrik Poeck
Research03 Jan 2024
Nature Cancer

Volume: 5, P: 187-208
Author Correction: A map of the rubisco biochemical landscape

Noam Prywes
Naiya R. Phillips
David F. Savage
Amendments and CorrectionsOpen Access10 Feb 2025
Nature

Volume: 638, P: E47
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide association analyses of 41,917 bipolar disorder cases and 371,549 controls of European ancestry provide new insights into the etiology of this disorder and identify novel therapeutic leads and potential opportunities for drug repurposing.

Niamh Mullins
Andreas J. Forstner
Ole A. Andreassen
Research17 May 2021
Nature Genetics

Volume: 53, P: 817-829
A Therapeutically Relevant Difference in Leukemia and Normal Stem Cell Self Renewal

Soledad Negrotto
Zhenbo Hu
Yogen Saunthararajah
ResearchOpen Access09 Apr 2009
Nature Precedings

P: 1
Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE

Caterina E. Faliti
Trinh T. P. Van
Ignacio Sanz
Amendments and CorrectionsOpen Access02 Dec 2024
Nature Immunology

Volume: 26, P: 148
A simple method for detecting chaos in nature

Daniel Toker et al. develop the Chaos Decision Tree Algorithm, a method for automatically assessing the presence and degree of chaos from empirical measurements. This study suggests that researchers can use this code to detect stochasticity, periodicity, or chaos in noisy empirical measurements.

Daniel Toker
Friedrich T. Sommer
Mark D’Esposito
ResearchOpen Access03 Jan 2020
Communications Biology

Volume: 3, P: 1-13
Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group

Sarah M. C. Colbert
Eric T. Monson
Lea Zillich
ReviewsOpen Access25 Sept 2025
Molecular Psychiatry

P: 1-11
Extreme sensitivity to ultraviolet light in the fungal pathogen causing white-nose syndrome of bats

White-nose syndrome, caused by the fungus Pseudogymnoascus destructans, is decimating North American bats. Here, Palmer et al. use comparative genomics to examine the evolutionary history of this pathogen, and show that it has lost a crucial DNA repair enzyme and is extremely sensitive to UV light.

Jonathan M. Palmer
Kevin P. Drees
Daniel L. Lindner
ResearchOpen Access02 Jan 2018
Nature Communications

Volume: 9, P: 1-10
Vertical and horizontal gene transfer shaped plant colonization and biomass degradation in the fungal genus Armillaria

The fungal genus Armillaria includes virulent necrotrophic pathogens, unusual wood decayers and the largest terrestrial organisms on Earth. Sahu et al. suggest that horizontal gene transfer contributed to the evolution of some of these unique traits.

Neha Sahu
Boris Indic
László G. Nagy
Research07 Aug 2023
Nature Microbiology

Volume: 8, P: 1668-1681
Tumour progression and liver regeneration—insights from animal models

Compelling evidence indicates that liver regeneration after portal vein occlusion and liver resection promotes tumour progression in patients with colorectal liver metastases. Here, the authors present clinical and experimental data from animal models of colorectal liver metastases pertaining to whether liver regeneration causes proliferation of tumour cells.

Chetana Lim
Francois Cauchy
Marc Pocard
Reviews09 Apr 2013
Nature Reviews Gastroenterology & Hepatology

Volume: 10, P: 452-462
Identification of unique rectal cancer-specific subtypes

Batuhan Kisakol
Anna Matveeva
Jochen H. M. Prehn
ResearchOpen Access26 Mar 2024
British Journal of Cancer

Volume: 130, P: 1809-1818
Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination

Xinrong Ma
Sreenivasu Karra
Dhananjaya D Kalvakolanu
Research05 Jul 2001
Oncogene

Volume: 20, P: 3703-3715
Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies

Anika Finze
Gloria Biechele
Matthias Brendel
ResearchOpen Access26 Jul 2023
Molecular Psychiatry

Volume: 28, P: 4438-4450
“Excellence R Us”: university research and the fetishisation of excellence

Samuel Moore
Cameron Neylon
Damian Pattinson
ResearchOpen Access19 Jan 2017
Palgrave Communications

Volume: 3, P: 1-13
Cross-hemispheric recruitment during action planning with increasing task demand

Sonja Schach
Daniel Alexander Braun
Axel Lindner
ResearchOpen Access16 Sept 2023
Scientific Reports

Volume: 13, P: 1-15
Role of Kindlin 2 in prostate cancer

Katarzyna Bialkowska
Lamyae El Khalki
Edward F. Plow
ResearchOpen Access27 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Wild-type egr1/Krox24 promotes and dominant-negative mutants inhibit, pluripotent differentiation of p19 embryonal carcinoma cells

Jacqueline Lanoix
Alaka Mullick
Daniel Skup
Research12 Oct 1998
Oncogene

Volume: 17, P: 2495-2504
A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis

Daniel Schwarzkopf
Claudia Tanja Matthaeus-Kraemer
Gabriele Wöbker
ResearchOpen Access10 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
CBL0137 increases the targeting efficacy of Rovalpituzumab tesirine against tumour-initiating cells in small cell lung cancer

Daniel J. Lindner
Gary Wildey
Sarmishtha De
ResearchOpen Access01 Dec 2020
British Journal of Cancer

Volume: 124, P: 893-895
CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma

Neetha Parameswaran
Liping Luo
Feng Lin
Research12 Aug 2023
Leukemia

Volume: 37, P: 2050-2057
Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics

Bei H Morrison
Joseph A Bauer
Daniel J Lindner
Research13 Mar 2002
Oncogene

Volume: 21, P: 1882-1889
I-BEAT: Ultrasonic method for online measurement of the energy distribution of a single ion bunch

Daniel Haffa
Rong Yang
Jörg Schreiber
ResearchOpen Access30 Apr 2019
Scientific Reports

Volume: 9, P: 1-7
Modulation of p53 dependent gene expression and cell death through thioredoxin-thioredoxin reductase by the Interferon-Retinoid combination

Jiadi Hu
Xinrong Ma
Dhananjaya V Kalvakolanu
Research17 Jul 2001
Oncogene

Volume: 20, P: 4235-4248
Degree of tumour vascularity correlates with drug accumulation and tumour response upon TNF-α-based isolated hepatic perfusion

B van Etten
M R de Vries
T L M ten Hagen
ResearchOpen Access28 Jan 2003
British Journal of Cancer

Volume: 88, P: 314-319
Rare germline alterations of myeloperoxidase predispose to myeloid neoplasms

Sunisa Kongkiatkamon
Laila Terkawi
Jaroslaw P. Maciejewski
Research27 Jun 2022
Leukemia

Volume: 36, P: 2086-2096
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Azmeraw T. Amare
Klaus Oliver Schubert
Bernhard T. Baune
Research16 Mar 2020
Molecular Psychiatry

Volume: 26, P: 2457-2470
An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution

Andreas Ulrich Lindner
Manuela Salvucci
Jochen H. M. Prehn
ResearchOpen Access09 Nov 2021
Cell Death & Differentiation

Volume: 29, P: 806-817
Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations

Xanthi Stachtea
Maurice B. Loughrey
Daniel B. Longley
ResearchOpen Access03 Nov 2021
Modern Pathology

Volume: 35, P: 564-576
Point-of-care lung ultrasound in COVID-19 patients: inter- and intra-observer agreement in a prospective observational study

Markus H. Lerchbaumer
Jonathan H. Lauryn
Frédéric Muench
ResearchOpen Access21 May 2021
Scientific Reports

Volume: 11, P: 1-11
Young and healthy C57BL/6 J mice performing sprint interval training reveal gender- and site-specific changes to the cortical bone

Robin Hollinski
Anja Osterberg
Brigitte Müller-Hilke
ResearchOpen Access24 Jan 2018
Scientific Reports

Volume: 8, P: 1-10
Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020–2022

Maren Doenhardt
Markus Hufnagel
Ulrich Zügge
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-15
Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis

Keiichi Asano
Courtney M. Nelson
Satoshi Hirohata
ResearchOpen Access08 Dec 2017
Scientific Reports

Volume: 7, P: 1-11
Erratum: Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination

Xinrong Ma
Sreenivasu Karra
Dhananjaya V Kalvakolanu
Amendments and Corrections19 Oct 2001
Oncogene

Volume: 20, P: 6651
cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation

Sana Khalid
Astrid Drasche
Jakob Troppmair
ResearchOpen Access12 Feb 2016
Scientific Reports

Volume: 6, P: 1-13
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Till F. M. Andlauer
Jose Guzman-Parra
Marcella Rietschel
ResearchOpen Access11 Nov 2019
Molecular Psychiatry

Volume: 26, P: 1286-1298
MEK inhibition abrogates sunitinib resistance in a renal cell carcinoma patient-derived xenograft model

C Marcela Diaz-Montero
Frances J Mao
Daniel J Lindner
ResearchOpen Access25 Aug 2016
British Journal of Cancer

Volume: 115, P: 920-928

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