Nature Search

The coming of age of metabolic surgery

Individuals with obesity who undergo bariatric surgery are much less likely to develop type 2 diabetes mellitus than are those receiving routine care, new findings reveal. Intriguingly, baseline data on surrogate measures of insulin resistance rather than BMI were predictive of the preventive effect of surgery on type 2 diabetes mellitus.

Francesco Rubino
David E. Cummings
News & Views13 Nov 2012
Nature Reviews Endocrinology

Volume: 8, P: 702-704
Immunotherapy for ALL takes the world by storm

In 2017, three groundbreaking immunotherapies for relapsed and/or refractory B-cell acute lymphoblastic leukaemia (ALL) were approved based on impressive outcomes observed in clinical trials. Additional breakthroughs included seminal research into ALL genomics and the importance of adherence to chemotherapy, which will have direct implications for clinical care.

David T. Teachey
Stephen P. Hunger
News & Views19 Dec 2017
Nature Reviews Clinical Oncology

Volume: 15, P: 69-70
Food Intake and Reward Mechanisms in Patients with Schizophrenia: Implications for Metabolic Disturbances and Treatment with Second-Generation Antipsychotic Agents

Igor Elman
David Borsook
Scott E Lukas
Reviews15 Mar 2006
Neuropsychopharmacology

Volume: 31, P: 2091-2120
Energy intake adaptations to acute isoenergetic active video games and exercise are similar in obese adolescents

J P Chaput
C Schwartz
D Thivel
Research25 Mar 2015
European Journal of Clinical Nutrition

Volume: 69, P: 1267-1271
Signatures of metabolic diseases on spermatogenesis and testicular metabolism

In this Review, the authors describe mechanisms through which metabolic disorders and metabolic-related hormonal status affect testes metabolism, spermatogenesis and male fertility. New findings on metabolic-related epigenetic signatures and paternal transgenerational inheritance of metabolic disorders are also discussed.

David F. Carrageta
Sara C. Pereira
Marco G. Alves
Reviews25 Mar 2024
Nature Reviews Urology

Volume: 21, P: 477-494
INTRINSIC REGULATION OF GLYCOGEN PARTICLES: LIVER v. SKELETAL MUSCLE

Philip A Gruppuso
David L Brautigan
Robert Schwartz
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 342
HYPERINSULINISM: A REVERSIBLE CAUSE OF HYPER-TROPHIC CARDIOMYOPATHY

James P Gutal
J Peter Harris
David J Dabbs
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 342
Layered reward signalling through octopamine and dopamine in Drosophila

Dopamine is synonymous with reward in mammals but associated with aversive reinforcement in insects, where reward seems to be signalled by octopamine; here it is shown that flies have discrete populations of dopamine neurons representing positive or negative values that are coordinately regulated by octopamine.

Christopher J. Burke
Wolf Huetteroth
Scott Waddell
Research28 Oct 2012
Nature

Volume: 492, P: 433-437
Examining the roles of body composition, energy expenditure and substrate metabolism in the control of daily energy intake in adolescents with obesity

D. Thivel
M. Hopkins
Y. Boirie
Research13 Mar 2025
International Journal of Obesity

Volume: 49, P: 1076-1083
Cannabis Sativa targets mediobasal hypothalamic neurons to stimulate appetite

Emma C. Wheeler
Pique Choi
Jon F. Davis
ResearchOpen Access27 Dec 2023
Scientific Reports

Volume: 13, P: 1-13
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Alzheimer disease (AD) and related dementias share numerous mechanistic and epidemiological similarities with type 2 diabetes mellitus (T2DM). However, whether these associations result from synergistic interactions between the disorders is unclear. This Review summarizes our current knowledge regarding insulin signalling and resistance in the brain and discusses current evidence concerning neurological impairment in T2DM and insulin resistance in AD.

Steven E. Arnold
Zoe Arvanitakis
David M. Nathan
Reviews29 Jan 2018
Nature Reviews Neurology

Volume: 14, P: 168-181
Combatting global grassland degradation

Grasslands provide key ecosystem services, but their protection is often ignored in sustainable policy. This Perspective describes grassland degradation and sets out the steps needed to protect these systems and promote their restoration.

Richard D. Bardgett
James M. Bullock
Hongxiao Shi
Reviews07 Sept 2021
Nature Reviews Earth & Environment

Volume: 2, P: 720-735
Initial sequencing and analysis of the human genome

Eric S. Lander
Lauren M. Linton
Michael J. Morgan
articles01 Feb 2001
Nature

Volume: 409, P: 860-921
The metabolic significance of peripheral tissue clocks

The contribution of peripheral tissue clocks to the maintenance of metabolic homeostasis, and their importance in shift work-associated metabolic disease

A. Louise Hunter
David A. Bechtold
ReviewsOpen Access26 Mar 2025
Communications Biology

Volume: 8, P: 1-11
Science and Progress in Australia

DAVID ORME MASSON
News06 Oct 1923
Nature

Volume: 112, P: 507-510
Circuit modules linking internal states and social behaviour in flies and mice

Small populations of interneurons in mice and inDrosophila melanogasterhave been shown to control both mating and aggression. Here, David Anderson proposes that these neuron populations may represent a conserved or analogous circuit node that controls reproductive behaviours in animals by promoting internal motivational, arousal or drive states.

David J. Anderson
Reviews18 Oct 2016
Nature Reviews Neuroscience

Volume: 17, P: 692-704
Satiation state-dependent dopaminergic control of foraging in Drosophila

Dan Landayan
David S. Feldman
Fred W. Wolf
ResearchOpen Access10 Apr 2018
Scientific Reports

Volume: 8, P: 1-9
Successful conservation of global waterbird populations depends on effective governance

Statistical modelling of global survey datasets of waterbirds as an indicator taxon for biodiversity changes in wetland ecosystems demonstrates that effective governance is the strongest predictor of species abundance increases and conservation benefits.

Tatsuya Amano
Tamás Székely
William J. Sutherland
Research20 Dec 2017
Nature

Volume: 553, P: 199-202
Biocultural approaches to well-being and sustainability indicators across scales

Biocultural approaches combining local values, knowledge, and needs with global ecological factors provide a fruitful indicator framework for assessing local and global well-being and sustainability, and help bridge the divide between them.

Eleanor J. Sterling
Christopher Filardi
Stacy D. Jupiter
Reviews23 Oct 2017
Nature Ecology & Evolution

Volume: 1, P: 1798-1806
Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience

Marios C. Panayi
Thomas Boerner
David M. Bannerman
ResearchOpen Access02 Dec 2022
Molecular Psychiatry

Volume: 28, P: 579-587
GluA1 AMPAR subunit deletion reduces the hedonic response to sucrose but leaves satiety and conditioned responses intact

Joseph M. Austen
Rolf Sprengel
David J. Sanderson
ResearchOpen Access07 Aug 2017
Scientific Reports

Volume: 7, P: 1-14
Pheromone components affect motivation and induce persistent modulation of associative learning and memory in honey bees

David Baracchi et al. show that honey bees exposed to geraniol, a component of an attractant pheromone, exhibit improved olfactory learning and memory while the opposite effect was seen in honey bees exposed to the aversive pheromone, 2- heptanone. These changes occurred through a modulation of appetitive motivation without affecting odor processing, suggesting an important role for pheromones as modulators of motivational and learning processes.

David Baracchi
Amélie Cabirol
Martin Giurfa
ResearchOpen Access17 Aug 2020
Communications Biology

Volume: 3, P: 1-9
The effect of an orally-dosed Caralluma Fimbriata extract on appetite control and body composition in overweight adults

Amanda Rao
David Briskey
Alistair R. Mallard
ResearchOpen Access24 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
Achievements and needs for the climate change scenario framework

The SSP–RCP scenario framework has been an important component of physical, social and integrated climate change research for the past decade. This Perspective reviews the successes of the framework and the challenges it faces, and provides suggestions for improvement moving forward.

Brian C. O’Neill
Timothy R. Carter
Ramon Pichs-Madruga
Reviews25 Nov 2020
Nature Climate Change

Volume: 10, P: 1074-1084
Forest-linked livelihoods in a globalized world

The landscape of forest and human activity is ever shifting, but new large-scale trends are causing exceptional changes and potential space for new conservation and development for communities dependent on forests.

Johan A. Oldekop
Laura Vang Rasmussen
Sarah J. Wilson
Reviews30 Nov 2020
Nature Plants

Volume: 6, P: 1400-1407
A framework for examining justice in food system transformations research

Global interest and investment in food system transformation should be accompanied by critical analysis of its justice implications. Multiple forms of injustice, and the potential role that research might play in exacerbating these, are key considerations for those engaging with food system transformation and justice.

Stephen Whitfield
Marina Apgar
Katharine Vincent
Comments & Opinion10 Jun 2021
Nature Food

Volume: 2, P: 383-385
Reduced neural response to food cues following exercise is accompanied by decreased energy intake in obese adolescents

S N Fearnbach
L Silvert
D Thivel
Research09 Oct 2015
International Journal of Obesity

Volume: 40, P: 77-83
Rapid delivery systems for future food security

Rajeev K. Varshney
Abhishek Bohra
Kadambot H. M. Siddique
Correspondence28 Sept 2021
Nature Biotechnology

Volume: 39, P: 1179-1181
Modeling of crop wild relative species identifies areas globally for in situ conservation

Holly Vincent et al. use species distribution modeling, climate change projections, and geographical analyses of more than 1200 crop wild relatives, identifying 150 key conservation areas most effective in preserving genetic diversity of crop wild relatives.

Holly Vincent
Ahmed Amri
Nigel Maxted
ResearchOpen Access23 Apr 2019
Communications Biology

Volume: 2, P: 1-8
A randomized controlled trial investigating the effect of liraglutide on self-reported liking and neural responses to food stimuli in participants with obesity

Géraldine Coppin
David Muñoz Tord
Zoltan Pataky
ResearchOpen Access25 Aug 2023
International Journal of Obesity

Volume: 47, P: 1224-1231
Innovative problem-solving in wild hyenas is reliable across time and contexts

Lily Johnson-Ulrich
Kay E. Holekamp
David Z. Hambrick
ResearchOpen Access03 Aug 2020
Scientific Reports

Volume: 10, P: 1-12
Endotoxin Increases Sleep and Brain Allopregnanolone Concentrations in Newborn Lambs

Saraid S Billiards
David W Walker
Jonathan J Hirst
Research01 Dec 2002
Pediatric Research

Volume: 52, P: 892-899
Comparative analysis of rural poverty and inequality in the UK and the US

Ruth McAreavey
David L. Brown
ResearchOpen Access15 Oct 2019
Palgrave Communications

Volume: 5, P: 1-10
Linking the influence and dependence of people on biodiversity across scales

Forest Isbell
Andrew Gonzalez
Anne Larigauderie
Reviews01 Jun 2017
Nature

Volume: 546, P: 65-72
Agricultural sustainability and intensive production practices

David Tilman
Kenneth G. Cassman
Stephen Polasky
Reviews08 Aug 2002
Nature

Volume: 418, P: 671-677
Measuring social determinants of health in the All of Us Research Program

Samantha Tesfaye
Robert M. Cronin
Cheryl R. Clark
ResearchOpen Access16 Apr 2024
Scientific Reports

Volume: 14, P: 1-12
Using Drosophila as a model insect

David Schneider
Reviews01 Dec 2000
Nature Reviews Genetics

Volume: 1, P: 218-226
Driven-dissipative non-equilibrium Bose–Einstein condensation of less than ten photons

Non-equilibrium Bose–Einstein condensation of 7 ± 2 photons is observed in a sculpted dye-filled microcavity. The small number of particles allows the authors to access and characterize the non-equilibrium dynamics of the bosonic modes.

Benjamin T. Walker
Lucas C. Flatten
Robert A. Nyman
Research10 Sept 2018
Nature Physics

Volume: 14, P: 1173-1177
Western diet, obesity and bariatric surgery sequentially modulated anxiety, eating patterns and brain responses to sucrose in adult Yucatan minipigs

Yentl Gautier
Damien Bergeat
David Val-Laillet
ResearchOpen Access18 Nov 2020
Scientific Reports

Volume: 10, P: 1-18
Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial

Carrie Cuttler
Amanda Stueber
Ethan Russo
ResearchOpen Access13 Jul 2024
Scientific Reports

Volume: 14, P: 1-14
Cleaner shrimp are a sustainable option to treat parasitic disease in farmed fish

David B. Vaughan
Alexandra S. Grutter
Kate S. Hutson
ResearchOpen Access18 Sept 2018
Scientific Reports

Volume: 8, P: 1-10
Effect of feed restriction and refeeding on performance and metabolism of European and Caribbean growing pigs in a tropical climate

Nausicaa Poullet
Jean-Christophe Bambou
Jean-Luc Gourdine
ResearchOpen Access19 Mar 2019
Scientific Reports

Volume: 9, P: 1-12
The effects of water temperature on the juvenile performance of two tropical damselfishes expatriating to temperate reefs

Lucas D. Djurichkovic
Jennifer M. Donelson
David J. Booth
ResearchOpen Access26 Sept 2019
Scientific Reports

Volume: 9, P: 1-9
Strong atom–field coupling for Bose–Einstein condensates in an optical cavity on a chip

'Strong coupling' of atomic Bose—Einstein condensates to cavities has remained an elusive goal, but this paper reports such an experiment, made possible by combining a fibre-based cavity with atom-chip technology. The set-up gives rise to a controlled, tuneable coupling rate.

Yves Colombe
Tilo Steinmetz
Jakob Reichel
Research08 Nov 2007
Nature

Volume: 450, P: 272-276
Building resilience to face recurring environmental crisis in African Sahel

Access to timely climate information is critical for empowering proactive decision-making to absorb climate shocks that would otherwise lead to large-scale humanitarian crises. The value of Rainwatch — a prototype geographical information system designed to increase interactions between local climate information users, their providers and supporting groups — is illustrated in the case of the unfavourable West African 2011 monsoon.

Emily Boyd
Rosalind J. Cornforth
Alan Brouder
Reviews16 Jun 2013
Nature Climate Change

Volume: 3, P: 631-637
Conduct disorder

Conduct disorder (CD) is a common and highly impairing psychiatric disorder that usually emerges in childhood or adolescence and is characterized by severe antisocial and aggressive behaviour. This Primer provides an overview of diagnostic approaches, evidence regarding the aetiology and pathophysiology of CD, and interventions and prevention programmes.

Graeme Fairchild
David J. Hawes
Stephane A. De Brito
Reviews27 Jun 2019
Nature Reviews Disease Primers

Volume: 5, P: 1-25
Nexus approaches to global sustainable development

Sustainability challenges, such as feeding people with fewer resources, involve challenges at the nexus of multiple issues, such as food, water and energy. This Review explores such nexus approaches, surveying their use towards sustainable development challenges, discussing examples, and proposing a systematic procedure and future directions.

Jianguo Liu
Vanessa Hull
Shuxin Li
Reviews14 Sept 2018
Nature Sustainability

Volume: 1, P: 466-476
Replanting unproductive palm oil with smallholder plantations can help achieve Sustainable Development Goals in Sumatra, Indonesia

Unproductive palm oil is hindering sustainable development in Sumatra, Indonesia, but its replanting through small plantations could contribute more to achieving the Sustainable Development Goals than industrial replanting, suggests a model-data analysis based on 25,067 villages.

Ariadna Fosch
Guilherme Ferraz de Arruda
Yamir Moreno
ResearchOpen Access16 Oct 2023
Communications Earth & Environment

Volume: 4, P: 1-12
Farming with crops and rocks to address global climate, food and soil security

To reduce climate warming we must stop adding CO₂ to the atmopshere, and develop approaches for removing it. Adding crushed, fast-reacting silicate rocks to croplands could improve productivity, restore soil quality and reduce atmospheric CO₂.

David J. Beerling
Jonathan R. Leake
James Hansen
Reviews19 Feb 2018
Nature Plants

Volume: 4, P: 138-147
Anti-CD7 CAR T cells for T-ALL: impressive early-stage efficacy

Chimeric antigen receptor (CAR) T cells have remarkable efficacy in patients with B cell acute lymphoblastic leukaemia (ALL), but have not been successful to date in patients with T cell ALL (T-ALL). Now, data from Pan and colleagues demonstrate the safety and impressive short-term efficacy of allogeneic donor-derived anti-CD7 CAR T cells in an early-phase clinical trial involving patients with relapsed and/or refractory T-ALL.

David T. Teachey
Stephen P. Hunger
News & Views27 Sept 2021
Nature Reviews Clinical Oncology

Volume: 18, P: 677-678

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