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Scientific Reports (16)
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Showing 1–50 of 53 results

Advanced filters: Author: Guoxin Chen Clear advanced filters

Spine endoscopic atlas: an open-source dataset for surgical instrument segmentation

Zhipeng Xu
Hong Wang
Xiang Liao
ResearchOpen Access02 Oct 2025
Scientific Data

Volume: 12, P: 1-11
Bovine lactoferrin drives cell cycle arrest and alters the transcriptomic profile of NSCLC cells

Jinxian Su
Yu Zhao
Haixia Zhang
ResearchOpen Access30 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Large oscillatory thermal hall effect in kagome metals

Detection of quantum oscillations in thermal transport could shed light on the origin of thermal Hall effect in correlated materials but it is challenging. Here the authors report quantum oscillations in the thermal Hall effect in the kagome metal CsV₃Sb₅ indicating strong violation of the Wiedemann–Franz law.

Dechen Zhang
Kuan-Wen Chen
Lu Li
ResearchOpen Access23 Jul 2024
Nature Communications

Volume: 15, P: 1-8
A high-entropy alloy showing gigapascal superelastic stress and nearly temperature-independent modulus

Designing superelastic materials with high critical stress, large recovery strain and temperature-independent modulus is desired but challenging. Here, the authors achieve these properties in a high-entropy alloy with multi-scale heterogeneities.

Junming Gou
Guoxin Liu
Xiaobing Ren
ResearchOpen Access31 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Controllable two-dimensional movement and redistribution of lithium ions in metal oxides

Ion transport properties are critical to some emerging technologies. Here, the authors show the controllable 2D movement and redistribution of Li-ions in metal oxides such as WO₃ by a magnetic field. The success is based on a current-driving model which also works for other cations including H⁺, Na⁺, Zn²⁺ and Ca²⁺.

Xiufeng Tang
Guoxin Chen
Jianyi Luo
ResearchOpen Access28 Jun 2019
Nature Communications

Volume: 10, P: 1-7
Antisolvent seeding of self-assembled monolayers for flexible monolithic perovskite/Cu(In,Ga)Se₂ tandem solar cells

The uneven surfaces of copper indium gallium selenide (CIGS) solar cells pose challenges for depositing the upper layers in flexible perovskite/CIGS tandem solar cells. Ying et al. tackle this issue using an antisolvent and seeding strategy, resulting in a certified efficiency of 23.8%.

Zhiqin Ying
Shiqian Su
Jichun Ye
Research18 Apr 2025
Nature Energy

Volume: 10, P: 737-749
Rapid sintering of high-efficiency phosphor-in-glass films for laser-driven light source

High-power laser lighting requires stable phosphor-in-glass films, but conventional sintering damages phosphors. Here, the authors develop infrared annealing which enables seconds-scale fabrication, minimizes interfacial damage and retains luminescence.

Pengfei Wang
Hang Lin
Yuansheng Wang
ResearchOpen Access21 Mar 2025
Nature Communications

Volume: 16, P: 1-12
Aggregation induced emission luminogen bacteria hybrid bionic robot for multimodal phototheranostics and immunotherapy

The utility of photosensitizers for cancer therapies is often hindered by a single photosensitizing mechanism, the need of multiple irradiations, and limited tumor penetration and retention. Here, the authors address these issues by developing an aggregation-induced emission luminogen bacteria hybrid bionic robot that enables multimodal imaging and therapy and activates anti-tumor immunity.

Liwei Zhu
Guangjie Song
Ying Li
ResearchOpen Access16 Mar 2025
Nature Communications

Volume: 16, P: 1-18
Experimental and numerical study on explosion resistance of polyurea-coated shelter in petrochemical industry

Meng Gu
Haozhe Wang
Xiaodong Ling
ResearchOpen Access04 Sept 2024
Scientific Reports

Volume: 14, P: 1-22
Author Correction: Magnetic breakdown and spin-zero effect in quantum oscillations in kagome metal CsV₃Sb₅

Kuan-Wen Chen
Guoxin Zheng
Lu Li
Amendments and CorrectionsOpen Access14 May 2024
Communications Materials

Volume: 5, P: 1
Biology-guided deep learning predicts prognosis and cancer immunotherapy response

The clinical application of data-driven deep learning models remains challenging. Here, a biology-guided deep learning approach allows the simultaneous prediction of the tumour immune and stromal microenvironment status as well as treatment outcomes from medical images in gastric cancer.

Yuming Jiang
Zhicheng Zhang
Ruijiang Li
ResearchOpen Access23 Aug 2023
Nature Communications

Volume: 14, P: 1-16
Fruquintinib plus paclitaxel versus placebo plus paclitaxel for gastric or gastroesophageal junction adenocarcinoma: the randomized phase 3 FRUTIGA trial

In a randomized, double-blind, placebo-controlled phase 3 trial, the anti-vascular endothelial growth factor receptor small-molecule inhibitor fruquintinib plus chemotherapy significantly extended progression-free survival, but not overall survival, as second-line therapy in patients with advanced gastric or gastroesophageal junction cancers.

Feng Wang
Lin Shen
Rui-Hua Xu
Research01 Jun 2024
Nature Medicine

Volume: 30, P: 2189-2198
Predicting postoperative peritoneal metastasis in gastric cancer with serosal invasion using a collagen nomogram

Gastric cancer can metastasise to the peritoneal cavity; predicting in which patients this will occur is important for clinical management of the disease. Here, the authors use multi-photon imaging to derive a collagen signature of the primary cancer that allows the prediction of metastasis.

Dexin Chen
Zhangyuanzhu Liu
Jun Yan
ResearchOpen Access08 Jan 2021
Nature Communications

Volume: 12, P: 1-11
Keratin-72 restricts HIV-1 infection in resting CD4⁺ T cells by sequestering capsids in intermediate filaments

HIV-1 replication in resting CD4+ T cells is inefficient due to host restriction factors. Here, the authors show that KRT72 is a Vpx-counteracted antiviral factor that binds incoming capsids to the cytoplasmic intermediate filament, thereby restricting HIV-1 infection in resting CD4+ T cells.

Yang He
Meng Xu
Guoxin Liang
ResearchOpen Access27 Mar 2025
Nature Communications

Volume: 16, P: 1-19
Prognostic and predictive value of a pathomics signature in gastric cancer

The current tumour-node-metastasis staging system alone cannot provide adequate information for prognosis and adjuvant chemotherapy benefits in patients with gastric cancer. Herein, the authors propose a pathomics signature that was derived from multiple features of haematoxylin and eosin-stained slides.

Dexin Chen
Meiting Fu
Jun Yan
ResearchOpen Access12 Nov 2022
Nature Communications

Volume: 13, P: 1-13
Noninvasive imaging of the tumor immune microenvironment correlates with response to immunotherapy in gastric cancer

Tumour microenvironment has been linked with immunotherapy response in gastric cancer. Here, the authors use CT-based radiomics to predict neutrophils-to-lymphocyte ratio and response to immunotherapy.

Weicai Huang
Yuming Jiang
Guoxin Li
ResearchOpen Access30 Aug 2022
Nature Communications

Volume: 13, P: 1-14
UBAP2L-driven stress granule formation links oxaliplatin resistance to gastric cancer

Mechanistic insights into the upregulation of UBAP2L-nucleated stress granules and its inhibitory effect on apoptosis in the context of oxaliplatin resistance in gastric cancer.

Chaorui Wu
Yu Yan
Guoxin Li
ResearchOpen Access13 Aug 2025
Communications Biology

Volume: 8, P: 1-17
Dynamic chloride ion adsorption on single iridium atom boosts seawater oxidation catalysis

The seawater oxidation reaction faces challenges from competitive chloride oxidation reaction. Herein, the authors have utilized chlorine adsorption to modulate the single-atom Ir coordination state and promote seawater oxidation and catalyst stability.

Xinxuan Duan
Qihao Sha
Xiaoming Sun
ResearchOpen Access04 Mar 2024
Nature Communications

Volume: 15, P: 1-11
A novel diagnosis methodology of gear oil for wind turbine combining Stepwise multivariate regression and clustered federated learning framework

Huihui Han
Ye Zhao
Yuchun Li
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-10
GDF1 ameliorates cognitive impairment induced by hearing loss

Pan et al. demonstrate that hearing loss promotes cognitive decline in an APP/PS1 mouse model of Alzheimer disease via inhibition of the GDF1 signaling pathway, unveiling GDF1 as a therapeutic target for Alzheimer disease.

Lina Pan
Chunrui Li
Zhentao Zhang
Research15 Mar 2024
Nature Aging

Volume: 4, P: 568-583
Liberal surgical laparoscopy reduction for acute intussusception: experience from a tertiary pediatric institute

Jian Yang
Guoyong Wang
Chunbao Guo
ResearchOpen Access03 Jan 2024
Scientific Reports

Volume: 14, P: 1-7
Effectiveness of the Young-Laplace equation at nanoscale

Hailong Liu
Guoxin Cao
ResearchOpen Access01 Apr 2016
Scientific Reports

Volume: 6, P: 1-10
New perspectives on molecular mechanisms underlying exercise-induced benefits in Parkinson’s disease

Xingyue Chen
Guoxin Zhang
Zhentao Zhang
ReviewsOpen Access23 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Real-time optical diagnosis of gastric cancer with serosal invasion using multiphoton imaging

Jun Yan
Yu Zheng
Guoxin Li
ResearchOpen Access08 Aug 2016
Scientific Reports

Volume: 6, P: 1-8
Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages

Here, using proteomics and cell-based assays, the authors show that HIV accessory protein Vpr mediates the degradation of host lysosomal-associated transmembrane protein 5 (LAPTM5) in monocyte-derived macrophages (MDM) to enhance infection in macrophages.

Li Zhao
Shumei Wang
Guoxin Liang
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-14
Magnetic breakdown and spin-zero effect in quantum oscillations in kagome metal CsV₃Sb₅

As recently proposed, the kagome metal CsV₃Sb₅ could host spontaneous orbital-currents due to Chern Fermi pockets, but these are challenging to detect. Here, a large g-factor enhancement in magnetic breakdown orbits, determined via quantum oscillations, provides a visible manifestation of Berry-curvature-induced large orbital moments.

Kuan-Wen Chen
Guoxin Zheng
Lu Li
ResearchOpen Access11 Nov 2023
Communications Materials

Volume: 4, P: 1-7
Predicting gastric cancer response to anti-HER2 therapy or anti-HER2 combined immunotherapy based on multi-modal data

Zifan Chen
Yang Chen
Lin Shen
ResearchOpen Access26 Aug 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-12
The PM20D1-NADA pathway protects against Parkinson’s disease

Yunying Yang
Sichun Chen
Zhentao Zhang
Research22 Aug 2024
Cell Death & Differentiation

Volume: 31, P: 1545-1560
Ti nanorod arrays with a medium density significantly promote osteogenesis and osteointegration

Chengyun Ning
Shuangying Wang
Chuanbin Mao
ResearchOpen Access08 Jan 2016
Scientific Reports

Volume: 6, P: 1-7
Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor

Xin Yi
Yuxuan Wu
Chengyun Ning
ResearchOpen Access11 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
Investigation of bioaccessibility of Cu, Fe, Mn, and Zn in market vegetables in the colon using PBET combined with SHIME

Naiyi Yin
Xiaolin Cai
Yanshan Cui
ResearchOpen Access14 Dec 2017
Scientific Reports

Volume: 7, P: 1-7
Closing yield gaps in China by empowering smallholder farmers

The authors report on attempts to increase the yield of smallholder farms in China using ten practices recommended by the Science and Technology Backyard for farming maize and wheat at county level.

Weifeng Zhang
Guoxin Cao
Zhengxia Dou
Research07 Sept 2016
Nature

Volume: 537, P: 671-674
Artificial intelligence assisted real-time recognition of intra-abdominal metastasis during laparoscopic gastric cancer surgery

Hao Chen
Longfei Gou
Guoxin Li
ResearchOpen Access05 Jan 2025
npj Digital Medicine

Volume: 8, P: 1-12
Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3

Vivek Iyer
Danilo Roman-Campos
Robert S. Kass
ResearchOpen Access20 Aug 2015
Scientific Reports

Volume: 5, P: 1-8
PPB-Affinity: Protein-Protein Binding Affinity dataset for AI-based protein drug discovery

Huaqing Liu
Peiyi Chen
Guoxin Fan
ResearchOpen Access03 Dec 2024
Scientific Data

Volume: 11, P: 1-11
Dynamic key vascular anatomy dataset for D2 lymph node dissection during laparoscopic gastric cancer surgery

Longfei Gou
Haolin Wu
Hao Chen
ResearchOpen Access29 May 2025
Scientific Data

Volume: 12, P: 1-12
Recent expansion of heat-activated retrotransposons in the coral symbiont Symbiodinium microadriaticum

Jit Ern Chen
Guoxin Cui
Manuel Aranda
ResearchOpen Access20 Oct 2017
The ISME Journal

Volume: 12, P: 639-643
Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer

Yanmei Peng
Xuetao Lei
Guoxin Li
ResearchOpen Access21 Feb 2024
Experimental & Molecular Medicine

Volume: 56, P: 441-452
Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis

Guoxin Xu
Yanping Gong
Tingwang Jiang
ResearchOpen Access17 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
The molecular chaperon AKR2A increases the mulberry chilling-tolerant capacity by maintaining SOD activity and unsaturated fatty acids composition

Lin Chen
Yuqi Hou
Guoxin Shen
ResearchOpen Access14 Aug 2018
Scientific Reports

Volume: 8, P: 1-11
Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in Apc^Min/+ mice

Guoxin Huang
Imran Khan
W. L. Wendy Hsiao
ResearchOpen Access02 Oct 2017
Scientific Reports

Volume: 7, P: 1-14
POLQ inhibition attenuates the stemness and ferroptosis resistance in gastric cancer cells via downregulation of dihydroorotate dehydrogenase

Yanmei Peng
Wenbo Zheng
Jiang Yu
ResearchOpen Access04 Apr 2024
Cell Death & Disease

Volume: 15, P: 1-13
Immunomodulatory activity of a water-soluble polysaccharide extracted from mussel on cyclophosphamide-induced immunosuppressive mice models

Xingwei Xiang
Rui Wang
Guoxin Shen
ResearchOpen Access27 Apr 2022
npj Science of Food

Volume: 6, P: 1-12
The HOXD9-mediated PAXIP1-AS1 regulates gastric cancer progression through PABPC1/PAK1 modulation

Jiaying Li
Miaomiao Pei
Jide Wang
ResearchOpen Access24 May 2023
Cell Death & Disease

Volume: 14, P: 1-14
Comparative Effectiveness of Di'ao Xin Xue Kang Capsule and Compound Danshen Tablet in Patients With Symptomatic Chronic Stable Angina

Yanan Yu
Siyuan Hu
Yongyan Wang
ResearchOpen Access14 Nov 2014
Scientific Reports

Volume: 4, P: 1-8
PAK6 promotes homologous-recombination to enhance chemoresistance to oxaliplatin through ATR/CHK1 signaling in gastric cancer

Weicai Huang
Zhen Han
Yuming Jiang
ResearchOpen Access28 Jul 2022
Cell Death & Disease

Volume: 13, P: 1-14
Exosomal circRELL1 serves as a miR-637 sponge to modulate gastric cancer progression via regulating autophagy activation

Huaiming Sang
Weifeng Zhang
Guoxin Zhang
ResearchOpen Access13 Jan 2022
Cell Death & Disease

Volume: 13, P: 1-11
The miR-3648/FRAT1-FRAT2/c-Myc negative feedback loop modulates the metastasis and invasion of gastric cancer cells

Weimei Tang
Miaomiao Pei
Jide Wang
ResearchOpen Access24 Sept 2022
Oncogene

Volume: 41, P: 4823-4838
Mental health of new undergraduate students before and after COVID-19 in China

Peng Lu
Lei Yang
Yuming Guo
ResearchOpen Access22 Sept 2021
Scientific Reports

Volume: 11, P: 1-9
CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer

Zhijun Xu
Chuncai Gu
Hao Liu
ResearchOpen Access23 Mar 2020
Cell Death & Disease

Volume: 11, P: 1-15

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