In recent years, considerable progress has been made towards understanding the mechanisms that underlie autoimmune inflammatory diseases of the PNS, such as Guillain–Barré syndrome and chronic inflammatory demyelinating polyneuropathy. As Meyer zu Hörste et al. discuss in this Review, many promising therapeutic approaches for these conditions have been established in animal models, but attempts to transfer this knowledge to the clinic have met with limited success to date.
- Gerd Meyer zu Hörste
- Hans-Peter Hartung
- Bernd C Kieseier