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Showing 51–100 of 179 results

Advanced filters: Author: Huimin Zhou Clear advanced filters

Threat of low-frequency high-intensity floods to global cropland and crop yields

Mitigation efforts to protect agricultural productivity against flooding focus on areas with high-frequency floods. However, agricultural regions with low-frequency floods experience a larger proportion of flood impacts, highlighting the urgency of prioritizing mitigation efforts in these regions.

Jichong Han
Zhao Zhang
Fulu Tao
Research24 Jun 2024
Nature Sustainability

Volume: 7, P: 994-1006
High-yield porphyrin production through metabolic engineering and biocatalysis

Porphyrins are produced at scale through metabolic engineering and optimization of CPIII purification.

Haihong Chen
Yaohong Wang
Lixin Zhang
Research05 Jun 2024
Nature Biotechnology

Volume: 43, P: 1717-1727
Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours

Nanoparticle penetration into tumours is an obstacle to cancer therapeutics. Here the authors show that the tumour vascular basement membrane constitutes a barrier that reduces nanoparticle delivery and demonstrate an immune-driven strategy to overcome the barrier, increasing nanoparticle movement into tumours.

Qin Wang
Qirui Liang
Yucai Wang
Research14 Sept 2023
Nature Nanotechnology

Volume: 19, P: 95-105
A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi

Unlike prokaryotic hosts, most genes in eukaryotes are transcribed to monocistronic mRNA for single protein translation. Here, the authors develop a polycistronic system for multiplexed and precalibrated expression of multiple genes, and show its application in constructing yeast cell factories for terpenoids production.

Qun Yue
Jie Meng
Shuobo Shi
ResearchOpen Access17 Jul 2023
Nature Communications

Volume: 14, P: 1-10
Exploring the interrelationship between myopia, psychological resilience, and emotion regulation in adolescents using a network analysis

Yingjun Xiang
Chengjun Lu
Jingfeng Mu
ResearchOpen Access16 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis

Here, the authors demonstrate that CXCL5 expression is increased in ankle joints of gouty arthritis model mice. CXCL5-neuronal CXCR2-TRPA1 axis contributes to gouty arthritis pain, neutrophil influx and joint inflammation.

Chengyu Yin
Boyu Liu
Boyi Liu
ResearchOpen Access16 Apr 2024
Nature Communications

Volume: 15, P: 1-21
Targeting dysregulated phago-/auto-lysosomes in Sertoli cells to ameliorate late-onset hypogonadism

Late-onset hypogonadism (LOH) can occur with male reproductive aging and is characterized by declining testosterone levels as well as other clinical symptoms. Here the authors show that dysregulated phago-/auto-lysosomes in Sertoli cells are a key feature of LOH, linking metabolism and aging, and that pharmaceutical targeting of lysosome dysfunction can alleviate LOH in mice.

Zhiwen Deng
Liangyu Zhao
Zhi Zhou
Research22 Apr 2024
Nature Aging

Volume: 4, P: 647-663
Origin of charge transfer and enhanced electron–phonon coupling in single unit-cell FeSe films on SrTiO₃

The origin of interface charge transfer and electron-phonon coupling in single unit-cell FeSe on SrTiO₃ remains elusive. Here, Zhang et al. report strengthened Ti-O bond and band bending at the FeSe/SrTiO₃ interface, which leads to several important processes.

Huimin Zhang
Ding Zhang
Xinhe Bao
ResearchOpen Access09 Aug 2017
Nature Communications

Volume: 8, P: 1-7
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification

Identifying and quantifying the biodistribution of synthetic polymeric nanoparticles in biological milieu is crucial for biomedical applications. Now, it has been shown that encoded polymeric amphiphiles with discrete molar masses undergo sequence- and length-dependent self-assembly into precise digital micelles that can be used in direct sequence reading and ex vivo label-free quantification assays.

Qiangqiang Shi
Hao Yin
Shiyong Liu
Research03 Nov 2022
Nature Chemistry

Volume: 15, P: 257-270
Frequency-dependent effects of subthalamic deep brain stimulation on motor symptoms in Parkinson’s disease: a meta-analysis of controlled trials

Dongning Su
Huimin Chen
Tao Feng
ResearchOpen Access27 Sept 2018
Scientific Reports

Volume: 8, P: 1-9
Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding

Cilia project from cells to serve sensory functions, and ciliary disruption can result in multiple disorders known as ciliopathies. Here the authors show that the ciliopathy gene TCTN1 functions to regulate the ciliary transition zone and ectosome formation.

Liang Wang
Xin Wen
Muqing Cao
ResearchOpen Access09 Jul 2022
Nature Communications

Volume: 13, P: 1-14
Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition

Engineering enzymes to perform new-to-nature reactions can address long-standing challenges in synthetic chemistry. Now a ketoreductase has been evolved to undergo a photoinduced single-electron-transfer pathway, thereby achieving an enantioselective Giese-type radical conjugate addition that yields α-chiral esters.

Xiaoqiang Huang
Jianqiang Feng
Huimin Zhao
Research02 May 2022
Nature Catalysis

Volume: 5, P: 586-593
Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum

Xingchen Li
Bo An
Jixian Qian
ResearchOpen Access28 Jan 2020
Scientific Reports

Volume: 10, P: 1-9
A deep-learning pipeline for the diagnosis and discrimination of viral, non-viral and COVID-19 pneumonia from chest X-ray images

An automated deep-learning pipeline for chest-X-ray-image standardization, lesion visualization and disease diagnosis can identify viral pneumonia caused by COVID-19, assess its severity, and discriminate it from other types of pneumonia.

Guangyu Wang
Xiaohong Liu
Tianxin Lin
Research15 Apr 2021
Nature Biomedical Engineering

Volume: 5, P: 509-521
Anlotinib enhances the efficacy of KRAS-G12C inhibitors through c-Myc/ORC2 axis inhibition in non-small cell lung cancer

Hongyu Liu
Chao Zhou
Baohui Han
ResearchOpen Access02 May 2025
Cell Death & Disease

Volume: 16, P: 1-11
Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence

A natural language processing system can support physicians in diagnostic assessments by extracting clinical information from electronic medical records to accurately predict diagnosis in pediatric patients.

Huiying Liang
Brian Y. Tsui
Huimin Xia
Research11 Feb 2019
Nature Medicine

Volume: 25, P: 433-438
Evolution characteristics of micromechanics provides insights into the microstructure of pharmaceutical tablets fabricated by bimodal mixtures

Mengtao Zhao
Anqi Luo
Chuanyun Dai
ResearchOpen Access20 Nov 2023
Scientific Reports

Volume: 13, P: 1-19
Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria

The C2 sulfonates taurine and isethionate are also present in the anaerobic mammalian gut, where they are converted into toxic H₂S by sulfate and sulfite-reducing bacteria. Here the authors characterise the O₂-sensitive enzyme IseG that catalyzes the C-S bond cleavage of isethionate and show that IseG also plays a key role in converting taurine into H₂S in Bilophila wadsworthia.

Meining Xing
Yifeng Wei
Yan Zhang
ResearchOpen Access08 Apr 2019
Nature Communications

Volume: 10, P: 1-11
The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor

Jumonji domain-containing histone demethylases regulate flowering in plants. Here Zheng et al. show that Arabidopsis JMJ13 is an H3K27me3 demethylase that recognizes H3K27me3 via hydrogen bonding and hydrophobic interactions and affects both photoperiod and temperature-dependent flowering responses.

Shuzhi Zheng
Hongmiao Hu
Jiamu Du
ResearchOpen Access21 Mar 2019
Nature Communications

Volume: 10, P: 1-11
Publisher Correction: Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L

Jisen Zhang
Xingtan Zhang
Ray Ming
Amendments and Corrections13 Nov 2018
Nature Genetics

Volume: 50, P: 1754
Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole

Skatole is a bacterial metabolite responsible for boar taint and the objectionable smell of manure. Here, the authors elucidate the final step of skatole biosynthesis, describing the discovery and biochemical characterization of the enzyme catalysing the conversion of indoleacetate into skatole.

Dazhi Liu
Yifeng Wei
Yan Zhang
ResearchOpen Access11 Oct 2018
Nature Communications

Volume: 9, P: 1-8
Nanovehicle-assisted monomer shuttling enables highly permeable and selective nanofiltration membranes for water purification

The development of advanced nanofiltration membranes should be compatible with existing manufacturing process to be practically useful. A process based on nanoemulsion-regulated interfacial polymerization allows the fabrication of low-cost and high-performance membranes.

Ruobin Dai
Huimin Zhou
Zhiwei Wang
Research27 Feb 2023
Nature Water

Volume: 1, P: 281-290
The criminal law protection mechanism for sustainable development in China – an empirical analysis of environmental pollution crime

Ying Zhou
Huimin Wang
Xiaohui An
ResearchOpen Access08 Jun 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-10
Distinguishing high-metastasis-potential circulating tumor cells through fluidic shear stress in a bloodstream-like microfluidic circulatory system

Wenxiu Li
Zhengjun Guo
Mengsu Yang
Research10 Jun 2024
Oncogene

Volume: 43, P: 2295-2306
Implementing machine learning in bipolar diagnosis in China

Yantao Ma
Jun Ji
Xin Yu
ResearchOpen Access18 Nov 2019
Translational Psychiatry

Volume: 9, P: 1-7
Optical properties of a hexagonal C/BN framework with sp² and sp³ hybridized bonds

Hongxia Bu
Haibin Zheng
Jingfen Zhao
ResearchOpen Access22 Apr 2020
Scientific Reports

Volume: 10, P: 1-9
Association of CVAI with BMD, FRAX scores, and osteoporosis risk in Chinese elderly patients with hypertension

Rui Ma
Xintian Cai
Nanfang Li
ResearchOpen Access22 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Molecular mechanisms of unique therapeutic potential of CUDC-907 for MEF2D fusion-driven BCP-ALL

Qing Xue
Ming Zhang
Sai-Juan Chen
ResearchOpen Access23 Jul 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-14
A Chinese pedigree with glucocorticoid remediable aldosteronism

Xiaoning Liu
Ling Jin
Jun Cai
Research30 Aug 2021
Hypertension Research

Volume: 44, P: 1428-1433
Gain-of-function PPM1D mutations attenuate ischemic stroke

Wenyan He
Yan Li
Wei-Na Jin
Research21 May 2025
Cell Death & Differentiation

P: 1-14
The discriminate value of event-related potentials in executive function of ADHD and comorbidity of ADHD and ASD

Chuanxue Tan
Huimin Zhou
Tingyu Li
ResearchOpen Access21 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
Willingness and driving factors of rural homestead withdrawal in china’s major grain producing areas from the new quality productivity perspective

Huimin Zhou
Xuning Qiao
Yanwei Yan
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Steroid metabolism gene variants and their genotype-phenotype correlations in Chinese early-onset hypertension patients

Fang Qin
Kai Liu
Lei Song
Research06 Aug 2019
Hypertension Research

Volume: 42, P: 1536-1543
Strong and high-conductivity hydrogels with all-polymer nanofibrous networks for applications as high-capacitance flexible electrodes

Huimin He
Yaqing Chen
Lizhi Xu
ResearchOpen Access09 Sept 2024
npj Flexible Electronics

Volume: 8, P: 1-11
Characterization of the self-assembly of New Jersey polyomavirus VP1 into virus-like particles and the virus seroprevalence in Japan

Xianfeng Zhou
Huimin Bai
Tian-Cheng Li
ResearchOpen Access11 Sept 2019
Scientific Reports

Volume: 9, P: 1-8
Using brachial-ankle pulse wave velocity to screen for metabolic syndrome in community populations

Guanghua Wang
Liang Zheng
Jue Li
ResearchOpen Access30 Mar 2015
Scientific Reports

Volume: 5, P: 1-7
Identification of functional cooperative mutations of SETD2 in human acute leukemia

Tao Cheng, Qian-fei Wang, Gang Huang and colleagues identify recurrent somatic loss-of-function mutations in SETD2 in individuals with acute leukemia. SETD2 encodes a histone H3K36 methyltransferase, and loss of SETD2 function causes global loss of H3K36 trimethylation and promotes leukemia stem cell self renewal.

Xiaofan Zhu
Fuhong He
Qian-fei Wang
Research09 Feb 2014
Nature Genetics

Volume: 46, P: 287-293
Effects of wall materials on the physicochemical properties of spray-dried bitter gourd (Momordica charantia L.) powders

Yuanyuan Deng
Guang Liu
Mingwei Zhang
ResearchOpen Access20 Jun 2024
npj Science of Food

Volume: 8, P: 1-16
Risk assessment of As, Cd, Cr, and Pb via the consumption of seafood in Haikou

Huimin Lin
Xinru Luo
Guihong Fang
ResearchOpen Access22 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes

The molecular mechanisms regulating myelination are only partially understood. Here authors show that Tsc1ablation in oligodendrocyte lineage activates ER stress and apoptotic programs in mice, and that enhancing PERK-eIF2α signalling partially rescues the myelination defects in Tsc1 mutants.

Minqing Jiang
Lei Liu
Q. Richard Lu
ResearchOpen Access15 Jul 2016
Nature Communications

Volume: 7, P: 1-15
Development and validation of a risk prediction model for diabetic retinopathy in type 2 diabetic patients

Chengjun Zhu
Jiaxi Zhu
Yun Liu
ResearchOpen Access28 Mar 2023
Scientific Reports

Volume: 13, P: 1-8
Identification and characterization of TCP transcription factor GmTCP670 associated with soybean development

Qi Wu
Huimin Wang
Wei Bai
ResearchOpen Access04 Jun 2025
Scientific Reports

Volume: 15, P: 1-17
SUMOylation facilitates the stability of BCR-ABL to promote chronic myeloid leukemia progression

Lu Zhang
Xuefeng Wang
Sai Ma
Research27 Mar 2025
Oncogene

Volume: 44, P: 1844-1855
Author Correction: A deep-learning pipeline for the diagnosis and discrimination of viral, non-viral and COVID-19 pneumonia from chest X-ray images

Guangyu Wang
Xiaohong Liu
Tianxin Lin
Amendments and Corrections29 Jul 2021
Nature Biomedical Engineering

Volume: 5, P: 943
Modeling urban land density with Gaussian and inverse S functions by analyzing urban expansion in Zhengzhou City

Hongfei Gao
Xuning Qiao
Qianxi Zheng
ResearchOpen Access24 May 2025
Scientific Reports

Volume: 15, P: 1-20
Bound exciton and free exciton states in GaSe thin slab

Chengrong Wei
Xi Chen
Jun-Feng Dai
ResearchOpen Access22 Sept 2016
Scientific Reports

Volume: 6, P: 1-6
Research on early warning model of coal spontaneous combustion based on interpretability

Huimin Zhao
Xu Zhou
Shishuo Wang
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-16
Unleashing green technology innovation in agribusiness: traditional environmental regulations, carbon trading, or synergies?

Wei Wang
Yanan She
Yunqiang Liu
ResearchOpen Access31 Jan 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-14
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model

Xiaodong Yang
Guole Liu
Xin Li
ResearchOpen Access08 Oct 2024
Cell Research

Volume: 34, P: 830-845
Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis

Lifeng Feng
Miaoqin Chen
Hongchuan Jin
ResearchOpen Access14 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-13

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