Ralph DeBerardinis obtained an MD and PhD from the University of Pennsylvania, then trained in Pediatrics and Medical Genetics at Children’s Hospital of Philadelphia. He moved to the University of Texas Southwestern Medical Center (UTSW) in 2008, serving as Chief of Pediatric Genetics and Metabolism from 2013 to 2024. He became an Investigator in the Howard Hughes Medical Institute in 2018 and was elected to the National Academy of Medicine in 2020. DeBerardinis’s current roles at UTSW include directing the Eugene McDermott Center for Human Growth and Development and the Genetic and Metabolic Disease Program in the Children’s Research Institute.