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Acta Pharmacologica Sinica (38)
Scientific Reports (27)
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Showing 1–50 of 101 results

Advanced filters: Author: Jian-hua Ma Clear advanced filters

Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils

Juan Qu
Yun-na Gan
Jian-hua Qiu
Research05 Mar 2012
Acta Pharmacologica Sinica

Volume: 33, P: 445-451
High-throughput screening assay for new ligands at human melatonin receptors

Jian-hua Yan
Hao-ran Su
Ming-wei Wang
Research01 Dec 2008
Acta Pharmacologica Sinica

Volume: 29, P: 1515-1521
Swietenia mahagony extract shows agonistic activity to PPAR γ and gives ameliorative effects on diabetic db/db mice

Dan-dan Li
Jun-hua Chen
Hua-liang Jiang
Research01 Feb 2005
Acta Pharmacologica Sinica

Volume: 26, P: 220-222
The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment

Analysis of tumor samples from patients with nasopharyngeal carcinoma shows that gemcitabine plus cisplatin chemotherapy activates a unique population of innate-like B cells, which enhance the cytotoxic CD8⁺ T cell response and are associated with better clinical outcomes.

Jiawei Lv
Yuan Wei
Jun Ma
Research06 Jun 2023
Nature Medicine

Volume: 29, P: 1424-1436
High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1

Jian-hua Yan
Qun-yi Li
Ming-wei Wang
Research01 Jun 2008
Acta Pharmacologica Sinica

Volume: 29, P: 752-758
Altered ATP-sensitive potassium channels may underscore obesity-triggered increase in blood pressure

Li-hong Fan
Hong-yan Tian
Yong-xiao Cao
Research01 Oct 2008
Acta Pharmacologica Sinica

Volume: 29, P: 1167-1174
Antiperovskite Chalco-Halides Ba₃(FeS₄)Cl, Ba₃(FeS₄)Br and Ba₃(FeSe₄)Br with Spin Super-Super Exchange

Xian Zhang
Kai Liu
Fu-Qiang Huang
ResearchOpen Access03 Nov 2015
Scientific Reports

Volume: 5, P: 1-8
Down-regulation of p210^bcr/abl by curcumin involves disrupting molecular chaperone functions of Hsp90

Li-xian Wu
Jian-hua Xu
Yuan-zhong Chen
Research01 Jun 2006
Acta Pharmacologica Sinica

Volume: 27, P: 694-699
Three-dimensional ordered mesoporous Co₃O₄ enhanced by Pd for oxygen evolution reaction

Qing Qu
Jian-Hua Zhang
Xihong Lu
ResearchOpen Access30 Jan 2017
Scientific Reports

Volume: 7, P: 1-9
Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays

Wei-Wen Cai
Jian-Hua Mao
Allan Bradley
Research01 Apr 2002
Nature Biotechnology

Volume: 20, P: 393-396
Curcumin synergistically augments bcr/abl phosphorothioate antisense oligonucleotides to inhibit growth of chronic myelogenous leukemia cells

Kun-zhong Zhang
Jian-hua Xu
Yuan-zhong Chen
Research01 Jan 2007
Acta Pharmacologica Sinica

Volume: 28, P: 105-110
Angiotensin-Converting Enzyme Gene 2350 G/A Polymorphism Is Associated with Left Ventricular Hypertrophy but Not Essential Hypertension

Min Pan
Jian-Hua Zhu
Xiang-Jun Yang
Research01 Jan 2007
Hypertension Research

Volume: 30, P: 31-37
Phenylphthalazines as small-molecule inhibitors of urea transporter UT-B and their binding model

Jian-hua Ran
Min Li
Bao-xue Yang
Research30 May 2016
Acta Pharmacologica Sinica

Volume: 37, P: 973-983
LASSO-based NTCP model for radiation-induced temporal lobe injury developing after intensity-modulated radiotherapy of nasopharyngeal carcinoma

Cheng Kong
Xiang-zhi Zhu
Yi-qin Zhang
ResearchOpen Access23 May 2016
Scientific Reports

Volume: 6, P: 1-8
Type-II Dirac photons

Hai-Xiao Wang
Yige Chen
Jian-Hua Jiang
ResearchOpen Access22 Sept 2017
npj Quantum Materials

Volume: 2, P: 1-8
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms

Hybrids of macrolides and quinolones, called macrolones, can overcome macrolide-induced resistance through new interactions between the quinolone moiety and the ribosome and can concurrently inhibit both ribosome and DNA gyrase targets.

Elena V. Aleksandrova
Cong-Xuan Ma
Alexander S. Mankin
Research22 Jul 2024
Nature Chemical Biology

Volume: 20, P: 1680-1690
Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade

Xiao-hong Deng
Jing-jing Liu
Jian-hua Huang
Research12 Oct 2018
Acta Pharmacologica Sinica

Volume: 40, P: 658-665
A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation

Zhao et al. identify an unexpected role of the nuclear export factor Nxf2 as a partner of Panoramix in mediating piRNA-guided silencing. Nxf2 counteracts Nxf1-centred nuclear RNA transport to prevent the export of transposon transcripts.

Kang Zhao
Sha Cheng
Yang Yu
Research30 Sept 2019
Nature Cell Biology

Volume: 21, P: 1261-1272
Observation of dynamic non-Hermitian skin effects

Characterizing and classifying dynamic non-Hermitian skin effect is a key challenge in nonHermitian physics. Here, authors illustrated rich non-Hermitian skin dynamics and dynamic phases in one-dimensional systems with glide-time reversal symmetry.

Zhen Li
Li-Wei Wang
Jian-Hua Jiang
ResearchOpen Access02 Aug 2024
Nature Communications

Volume: 15, P: 1-9
Machine learning based early warning system enables accurate mortality risk prediction for COVID-19

Methods to stratify patients according to mortality risk are essential to allocate limited heath resources during the COVID-19 crisis. Here, using machine learning methods, the authors present a mortality risk prediction model for COVID-19 that uses patients’ clinical data on admission to stratify patients by mortality risk.

Yue Gao
Guang-Yao Cai
Qing-Lei Gao
ResearchOpen Access06 Oct 2020
Nature Communications

Volume: 11, P: 1-10
Reproductive phasiRNAs regulate reprogramming of gene expression and meiotic progression in rice

21-nucleotide phased secondary siRNAs are expressed in the developing rice anthers during meiosis. Here, the authors show that phasiRNAs can cleave target mRNA and act to ensure the progression of meiosis and fertility in rice.

Yu-Chan Zhang
Meng-Qi Lei
Yue-Qin Chen
ResearchOpen Access27 Nov 2020
Nature Communications

Volume: 11, P: 1-11
Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling

HU is among the most conserved and abundant nucleoid-associated proteins in eubacteria. Here the authors investigate the role of histone-like proteins (HU) in the 3D organization of the bacteria DNA and show via soft X-ray tomography the process of nucleoid remodeling.

Soumya G. Remesh
Subhash C. Verma
Michal Hammel
ResearchOpen Access09 Jun 2020
Nature Communications

Volume: 11, P: 1-12
C1206, a novel curcumin derivative, potently inhibits Hsp90 and human chronic myeloid leukemia cells in vitro

Ying-juan Fan
Yi-xiang Zhou
Jian-hua Xu
Research07 Dec 2017
Acta Pharmacologica Sinica

Volume: 39, P: 649-658
Acteoside-containing caffeic acid is bioactive functional group of antifibrotic effect by suppressing inflammation via inhibiting AHR nuclear translocation in chronic kidney disease

Yan-ni Wang
Xin Wu
Ying-yong Zhao
Research20 Jun 2025
Acta Pharmacologica Sinica

P: 1-14
Altered respiratory virome and serum cytokine profile associated with recurrent respiratory tract infections in children

Here, the authors determine the respiratory virome and serum cytokine profile in children diagnosed with acute respiratory tract infections (ARTI) and show that relative abundance of Propionibacterium phages as well as serum levels of TIMP-1 and PDGF-BB are increased in multiple ARTIs compared with single ARTI.

Yanpeng Li
Xuemin Fu
Chiyu Zhang
ResearchOpen Access23 May 2019
Nature Communications

Volume: 10, P: 1-12
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B

Zheng Wang
Zeng-xia Li
Yong-jun Dang
Research14 Aug 2020
Acta Pharmacologica Sinica

Volume: 42, P: 801-813
The extracellular domain of Staphylococcus aureus LtaS binds insulin and induces insulin resistance during infection

The extracellular domain of the cell wall protein LtaS is an insulin-binding protein and mediates insulin resistance during Staphylococcus aureus infection.

Yu Liu
Fang-Jie Liu
Guang Yang
Research16 Apr 2018
Nature Microbiology

Volume: 3, P: 622-631
Tailoring exciton and excimer emission in an exfoliated ultrathin 2D metal-organic framework

Two dimensional (2D) metal-organic frameworks have demonstrated unique photophysical properties compared to their bulk analogs. Here, the authors demonstrate that exfoliation of 2D MOFs can suppress interlayer exciton-related emission, allowing for modulation of the overall emission color and switching of optical memory states.

Wei-Ming Liao
Jian-Hua Zhang
Cheng-Yong Su
ResearchOpen Access19 Jun 2018
Nature Communications

Volume: 9, P: 1-9
Preclinical assessment of the distribution, metabolism, and excretion of S-propargyl-cysteine, a novel H₂S donor, in Sprague-Dawley rats

Yuan-ting Zheng
Jian-hua Zhu
Wei-min Cai
Research30 Apr 2012
Acta Pharmacologica Sinica

Volume: 33, P: 839-844
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

Amanda Ewart-Toland
Paraskevi Briassouli
Allan Balmain
Research27 Jul 2003
Nature Genetics

Volume: 34, P: 403-412
Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas

Directly comparing patterns of gene expression in matched normal and cancerous tissues provides a powerful tool to identify drivers of tumour progression. Here the authors discover genes that are recruited into mitotic signalling networks in lung adenocarcinoma.

Il-Jin Kim
David Quigley
Allan Balmain
Research16 Apr 2013
Nature Communications

Volume: 4, P: 1-11
Structure-based drug design of a novel family of chalcones as PPARα agonists: virtual screening, synthesis, and biological activities in vitro

Xiang-hua Li
Han-jun Zou
Jian-hua Shen
Research01 Dec 2007
Acta Pharmacologica Sinica

Volume: 28, P: 2040-2052
Parasitic insect-derived miRNAs modulate host development

The moth Plutella xylostella during its larval stage is the host of the endoparasitic wasp Cotesia vestalis. Here the authors show that the parasitoids deliver microRNAs to their hosts through their symbiotic virus and specialized cells leading to induced developmental delay.

Zhi-zhi Wang
Xi-qian Ye
Xue-xin Chen
ResearchOpen Access07 Jun 2018
Nature Communications

Volume: 9, P: 1-9
Cardioprotective effects of diltiazem reevaluated by a novel myocardial ischemic model in Chinese miniature swine

Jian-xun Liu
Zhen Yu
Yan-lei Ma
Research01 Jan 2007
Acta Pharmacologica Sinica

Volume: 28, P: 52-57
Management of glycemic variation in diabetic patients receiving parenteral nutrition by continuous subcutaneous insulin infusion (CSII) therapy

Feng-fei Li
Wen-li Zhang
Jian-hua Ma
ResearchOpen Access12 Apr 2018
Scientific Reports

Volume: 8, P: 1-7
Metformin add-on continuous subcutaneous insulin infusion on precise insulin doses in patients with type 2 diabetes

Feng-fei Li
Bing-li Liu
Jian-hua Ma
ResearchOpen Access26 Jun 2018
Scientific Reports

Volume: 8, P: 1-7
Visceral adipose tissue-derived extracellular vesicles promote stress susceptibility in obese mice via miR-140-5p

Hao Wang
Li Zhang
Gang Hu
Research10 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1221-1235
Features of glycemic variations in drug naïve type 2 diabetic patients with different HbA_1c values

Feng-fei Li
Bing-li Liu
Jian-hua Ma
ResearchOpen Access08 May 2017
Scientific Reports

Volume: 7, P: 1-7
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition

Shan-yao Ma
Meng-meng Ning
Ying Leng
Research06 Jun 2016
Acta Pharmacologica Sinica

Volume: 37, P: 1359-1369
GFPBW1, a β-glucan from Grifola frondosa as vaccine adjuvant: APCs activation and maturation

Xiang He
Jiang-ling Lu
Yi-fu Yang
Research21 Jun 2024
Acta Pharmacologica Sinica

Volume: 45, P: 2394-2404
Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment

Xiao-yan Jiang
Xiao-song Zhu
Ji-min Cao
Research27 Mar 2017
Acta Pharmacologica Sinica

Volume: 38, P: 1048-1058
Inhibitory effects of idoxifene on hepatic fibrosis in rats

Ya-jun Zhou
Dong-mei Yin
Xing Wang
Research01 May 2005
Acta Pharmacologica Sinica

Volume: 26, P: 581-586
Anatomy of the retrohepatic tunnel in a Chinese population and its clinical application in liver surgery

Wang Zheng
Ding Zi-hai
Lin Yi-xiong
ResearchOpen Access21 Mar 2017
Scientific Reports

Volume: 7, P: 1-8
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

Xuejun Zhang and colleagues report results of a genome-wide association study of systemic lupus erythematosus (SLE) in a Chinese Han population. Their work identifies nine new SLE susceptibility loci and reveals overlap in the spectrum of risk alleles shared between Chinese Han and European populations.

Jian-Wen Han
Hou-Feng Zheng
Xue-Jun Zhang
Research18 Oct 2009
Nature Genetics

Volume: 41, P: 1234-1237
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma

Yu-Pei Chen
Jian-Hua Yin
Jun Ma
ResearchOpen Access20 Jul 2020
Cell Research

Volume: 30, P: 1024-1042
Evolutionary history of the angiosperm flora of China

A dated phylogeny and spatial distribution data for Chinese angiosperms show that eastern China has tended to act as a refugium for older taxa whereas western China has acted as a centre for their evolutionary diversification.

Li-Min Lu
Ling-Feng Mao
Zhi-Duan Chen
Research31 Jan 2018
Nature

Volume: 554, P: 234-238
Research on object detection and recognition in remote sensing images based on YOLOv11

Lu-hao He
Yong-zhang Zhou
Jian-hua Ma
ResearchOpen Access23 Apr 2025
Scientific Reports

Volume: 15, P: 1-25
Comprehensive analysis of Enterobacteriaceae IncX plasmids reveals robust conjugation regulators PrfaH, H-NS, and conjugation-fitness tradeoff

A detailed analysis of IncX plasmids identifies PrfaH as crucial for conjugation and H-NS as a regulator of the balance between conjugation and host fitness, highlighting PrfaH as a potential target for combating antimicrobial resistance.

Jun Yang
Yaoyao Lu
Jian-Hua Liu
ResearchOpen Access04 Mar 2025
Communications Biology

Volume: 8, P: 1-17
Mass spectrometry imaging for in situ kinetic histochemistry

Katherine B. Louie
Benjamin P. Bowen
Trent R. Northen
ResearchOpen Access15 Apr 2013
Scientific Reports

Volume: 3, P: 1-7
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway

Qi-qi Song
Li-ping Lin
Gang Hu
Research08 Dec 2022
Acta Pharmacologica Sinica

Volume: 44, P: 1262-1276

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