Nature Search

FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice

Hepatic ischemia-reperfusion injury (IRI) is a common complication that occurs during hepatic resection and transplantation. Here the authors show that Hepatic stellate cells secrete FGF18 which alleviates hepatocyte injury by USP16/KEAP1/Nrf2 signaling.

Gaozan Tong
Yiming Chen
XiaoKun Li
ResearchOpen Access30 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Solar-driven scalable hygroscopic gel for recycling water from passive plant transpiration and soil evaporation

A considerable portion of human water usage is allocated to agriculture, yet optimizing water resources remains a persistent challenge. A promising solution lies in solar-powered technology integrated with hygroscopic porous gel, which captures water vapour from both plant transpiration and soil evaporation. This approach holds potential to enhance water utilization efficiency within greenhouses.

Hao Zou
Xinge Yang
Ruzhu Wang
Research10 Jul 2024
Nature Water

Volume: 2, P: 663-673
CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

The transcription factor CREM is a pivotal regulator of NK cell function, making CREM a valuable target to increase the efficacy of anticancer immunotherapies based on this cell population and chimeric antigen receptors.

Hind Rafei
Rafet Basar
Katayoun Rezvani
ResearchOpen Access04 Jun 2025
Nature

Volume: 643, P: 1076-1086
Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice

Although the role of FGFs in cardiovascular disease has attracted extensive attention, the potential role of FGF18 in pathological cardiac hypertrophy remains unknown. Here, the authors show the cardioprotective effect of FGF18 is mediated by maintaining redox homeostasis through FYN/Nox4 signaling.

Gen Chen
Ning An
Xu Wang
ResearchOpen Access04 Mar 2023
Nature Communications

Volume: 14, P: 1-18
Active phase discovery in heterogeneous catalysis via topology-guided sampling and machine learning

Discovering active phases in heterocatalysis entails efficient configuration sampling and optimization. Here, the authors developed a framework based on topology and machine learning to effectively explore the active structures, applied in the CO2 electroreduction and Oxygen Reduction Reaction

Shisheng Zheng
Xi-Ming Zhang
Jian-Feng Li
ResearchOpen Access14 Mar 2025
Nature Communications

Volume: 16, P: 1-13
Defect-based Lewis pairs on hydrophobic MnO mesocrystals for robust and efficient ozone decomposition

Designing catalysts that efficiently and sustainably break down O₃ in humid conditions remains a challenge. Here, the authors present a strategy for incorporating Lewis pairs into the catalyst as electron donor-acceptor sites to achieve robust O₃ decomposition in humid environments.

Jingling Yang
Ziran Yi
Mingshan Zhu
ResearchOpen Access25 Mar 2025
Nature Communications

Volume: 16, P: 1-9
Complex structure and activation mechanism of arginine kinase McsB by McsA

Cryo-electron microscopy and biochemical analysis reveal the activation mechanism of protein arginine kinase McsB by its activator McsA for protein quality control under stress in Gram-positive bacteria.

Kai Lu
Bingnan Luo
Zong-Wan Mao
Research04 Sept 2024
Nature Chemical Biology

Volume: 21, P: 402-411
Efficient catalyst-free N₂ fixation by water radical cations under ambient conditions

The growth and sustainable development of humanity is heavily dependent upon N₂ fixation. Herein, authors developed an ambient catalyst-free disproportionation of N₂ by water plasma to yield economically valuable nitroxyl and hydroxylamine products.

Xiaoping Zhang
Rui Su
Huanwen Chen
ResearchOpen Access20 Feb 2024
Nature Communications

Volume: 15, P: 1-12
Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation

Injecting Cas9 and gRNA into an animal zygote often produces mosaicism and random biallelic targeting. Here, the authors use pronuclear transfer to reduce mosaicism and selectively target parental alleles.

Yanhe Li
Yuteng Weng
Shaorong Gao
ResearchOpen Access14 Sept 2020
Nature Communications

Volume: 11, P: 1-12
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Genome-wide association analyses across individuals of East Asian and European ancestries identify new risk loci for inflammatory bowel diseases. A polygenic risk score derived from the combined datasets shows improved prediction accuracy.

Zhanju Liu
Ruize Liu
Hailiang Huang
Research08 May 2023
Nature Genetics

Volume: 55, P: 796-806
Spatial evolution characteristics and influencing factors of sports brand resources in Chinese urban agglomerations

Xuesi Zhong
Jingling Wang
Zejun Zhong
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Next-generation water-saving strategies for greenhouses using a nexus approach with modern technologies

The food and water crisis demands innovative agricultural solutions. Here, the authors propose a next-generation greenhouse water-saving strategy by integrating advanced technologies, including atmospheric water harvesting, superabsorbent polymers, radiative cooling, and solar-driven desalination.

Hao Zou
Fan Wang
Ruzhu Wang
ReviewsOpen Access01 Mar 2025
Nature Communications

Volume: 16, P: 1-12
EMMPRIN Down-regulating miR-106a/b Modifies Breast Cancer Stem-like Cell Properties via Interaction with Fibroblasts Through STAT3 and HIF-1α

Yonglei Liu
Jingling Zhang
Meilin Li
ResearchOpen Access21 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
Maternal COVID-19 infection associated with offspring neurodevelopmental disorders

Lian Duan
Huamin Yin
Zhendong Wang
Research09 Nov 2024
Molecular Psychiatry

Volume: 30, P: 2108-2118
Unveiling the mitochondrial genome of Salvia splendens insights into the evolutionary traits within the genus Salvia

Heyu Yang
Yang Ni
Chang Liu
ResearchOpen Access17 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
Social affiliation is sufficient to provoke the partner-advantage

Chia-huei Tseng
Li Jingling
Miao Cheng
ResearchOpen Access09 Dec 2022
Scientific Reports

Volume: 12, P: 1-11
Class A1 scavenger receptor antibody improves murine colitis by influencing macrophage and gut microbiota

Jingling Su
Lupeng Liu
Chenxi Xie
ResearchOpen Access10 Aug 2024
Scientific Reports

Volume: 14, P: 1-9
Testing the effects of perceptual grouping on visual search in older adults

Li Jingling
Sung-Nan Lai
ResearchOpen Access10 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
LncTUG1 promotes hepatocellular carcinoma immune evasion via upregulating PD-L1 expression

Rongshou Wu
Weiwei Liu
Enliang Li
ResearchOpen Access09 Oct 2023
Scientific Reports

Volume: 13, P: 1-11
Metabolic control of histone acetylation for precise and timely regulation of minor ZGA in early mammalian embryos

Jingyu Li
Jiaming Zhang
Qingran Kong
ResearchOpen Access27 Sept 2022
Cell Discovery

Volume: 8, P: 1-20
Current evidence on circRNAs as potential theranostic markers for detecting chemoresistance in breast cancer: a systematic review and meta‑analysis

Zixin Zhu
Hui Jiang
Jinbo Liu
ResearchOpen Access20 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
One-pot synthesis of cyclodextrin-based radial poly[n]catenanes

There are several structural motifs commonly reported for polycatenanes although radial polycatenanes remain poorly studied. Here, the authors report the facile synthesis of cyclodextrin based radial polycatenanes composed of more than ten rings via a polypseudorotaxane intermediate.

Taishi Higashi
Kentaro Morita
Jun Li
ResearchOpen Access03 Jul 2019
Communications Chemistry

Volume: 2, P: 1-8
Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background

Jingling Shen
Dan Shi
Zhenghua Li
Research14 Mar 2016
Laboratory Investigation

Volume: 96, P: 680-691
Effects of seedling age and cultivation density on agronomic characteristics and grain yield of mechanically transplanted rice

Qihua Liu
Xuebiao Zhou
Caiyun Xin
ResearchOpen Access26 Oct 2017
Scientific Reports

Volume: 7, P: 1-10
Rescue of retinal morphology and function in a humanized mouse at the mouse retinol-binding protein locus

Li Liu
Tomohiro Suzuki
Zhenghua Li
Research30 Jan 2017
Laboratory Investigation

Volume: 97, P: 395-408
Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci

Xiangshun Li
Yanyi Lyu
Zhenghua Li
Research12 Jan 2018
Laboratory Investigation

Volume: 98, P: 512-524
Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury

Chao Deng
Lin Zhao
Yang Yang
Reviews26 May 2021
Acta Pharmacologica Sinica

Volume: 43, P: 520-528

Search

FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice

Solar-driven scalable hygroscopic gel for recycling water from passive plant transpiration and soil evaporation

CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice

Active phase discovery in heterogeneous catalysis via topology-guided sampling and machine learning

Defect-based Lewis pairs on hydrophobic MnO mesocrystals for robust and efficient ozone decomposition

Complex structure and activation mechanism of arginine kinase McsB by McsA

Efficient catalyst-free N₂ fixation by water radical cations under ambient conditions

Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Spatial evolution characteristics and influencing factors of sports brand resources in Chinese urban agglomerations

Next-generation water-saving strategies for greenhouses using a nexus approach with modern technologies

EMMPRIN Down-regulating miR-106a/b Modifies Breast Cancer Stem-like Cell Properties via Interaction with Fibroblasts Through STAT3 and HIF-1α

Maternal COVID-19 infection associated with offspring neurodevelopmental disorders

Unveiling the mitochondrial genome of Salvia splendens insights into the evolutionary traits within the genus Salvia

Social affiliation is sufficient to provoke the partner-advantage

Class A1 scavenger receptor antibody improves murine colitis by influencing macrophage and gut microbiota

Testing the effects of perceptual grouping on visual search in older adults

LncTUG1 promotes hepatocellular carcinoma immune evasion via upregulating PD-L1 expression

Metabolic control of histone acetylation for precise and timely regulation of minor ZGA in early mammalian embryos

Current evidence on circRNAs as potential theranostic markers for detecting chemoresistance in breast cancer: a systematic review and meta‑analysis

One-pot synthesis of cyclodextrin-based radial poly[n]catenanes

Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background

Effects of seedling age and cultivation density on agronomic characteristics and grain yield of mechanically transplanted rice

Rescue of retinal morphology and function in a humanized mouse at the mouse retinol-binding protein locus

Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci

Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury

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