Nature Search

CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa

In this work, authors show that deletion of FprB enhances the antibacterial activity of gallium against Pseudomonas aeruginosa, revealing a combination strategy and demonstrating the utility of CRISPRi-seq for therapeutic target discovery.

Yu Zhang
Tingting Zhang
Xue Liu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Research on intelligent regulation of layered water injection based on reinforcement learning SAC algorithm

Jinzhao Hu
Deli Jia
Fushen Ren
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-17
Experimental quantum computational chemistry with optimized unitary coupled cluster ansatz

The application of quantum computing to computational chemistry faces various experimental and theoretical challenges. Now, a quantum simulation on a noisy quantum device has achieved chemical accuracy for small H₂ and LiH molecules.

Shaojun Guo
Jinzhao Sun
Jian-Wei Pan
Research11 Jun 2024
Nature Physics

Volume: 20, P: 1240-1246
The beneficial role of Asian-based RecurIndex test in the prognostic prediction in Chinese male breast cancer patients

Shuo Zhang
Beichen Liu
Yunjiang Liu
ResearchOpen Access07 Apr 2021
Scientific Reports

Volume: 11, P: 1-8
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

How epigenetic regulation affects pancreatic development is unclear. Here, the authors show that the histone demethylase LSD1 regulates the epigenetic state of developmental enhancers during pancreatic specification and controls how these enhancers respond to extracellular signals, namely retinoic acid.

Nicholas K. Vinckier
Nisha A. Patel
Maike Sander
ResearchOpen Access29 Apr 2020
Nature Communications

Volume: 11, P: 1-15
The intelligent selenium-enriched tea withering control system

Shuang Ren
Sanjun Liu
Didi Lu
ResearchOpen Access15 Jan 2025
Scientific Reports

Volume: 15, P: 1-12
Different hydrogen isotope fractionations during lipid formation in higher plants: Implications for paleohydrology reconstruction at a global scale

Jinzhao Liu
Weiguo Liu
Hong Yang
ResearchOpen Access25 Jan 2016
Scientific Reports

Volume: 6, P: 1-10
Migration and plugging laws of plugging-selection balls in fine profile control process of layered waterflooding wells

Yan An
Fushen Ren
Min Luo
ResearchOpen Access13 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
Comprehensive large-scale nucleic acid–testing strategies support China’s sustained containment of COVID-19

Zhongjie Li
Fengfeng Liu
Zijian Feng
Correspondence15 Apr 2021
Nature Medicine

Volume: 27, P: 740-742
Some convergently three-term trust region conjugate gradient algorithms under gradient function non-Lipschitz continuity

Wujie Hu
Jinzhao Wu
Gonglin Yuan
ResearchOpen Access13 May 2024
Scientific Reports

Volume: 14, P: 1-15
Comparing watershed black locust afforestation and natural revegetation impacts on soil nitrogen on the Loess Plateau of China

Zhao Jin
Xiangru Li
Buli Cui
ResearchOpen Access26 Apr 2016
Scientific Reports

Volume: 6, P: 1-8
Light convolutional neural network by neural architecture search and model pruning for bearing fault diagnosis and remaining useful life prediction

Diwang Ruan
Jinzhao Han
Clemens Gühmann
ResearchOpen Access04 Apr 2023
Scientific Reports

Volume: 13, P: 1-19
Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression

We present a protocol for generating mouse ESC-derived induced neuronal cells via lentiviral Tet-On inducible expression of NGN2 for the direct comparison of human and mouse neuronal populations.

Yingfei Liu
Jinzhao Wang
Marius Wernig
Protocols18 Aug 2023
Nature Protocols

Volume: 18, P: 2954-2974
Dissecting the vital role of dietary changes in food security assessment under climate change

Dietary changes can potentially alleviate climate change’s impact on global food supply, benefiting up to 42% of the global population and potentially addressing the food security crisis, according to assessment of dietary changes’ impact on food security.

Jin Zhao
Zhentao Zhang
Xiaoguang Yang
ResearchOpen Access17 Aug 2024
Communications Earth & Environment

Volume: 5, P: 1-9

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CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa

Research on intelligent regulation of layered water injection based on reinforcement learning SAC algorithm

Experimental quantum computational chemistry with optimized unitary coupled cluster ansatz

The beneficial role of Asian-based RecurIndex test in the prognostic prediction in Chinese male breast cancer patients

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

The intelligent selenium-enriched tea withering control system

Different hydrogen isotope fractionations during lipid formation in higher plants: Implications for paleohydrology reconstruction at a global scale

Migration and plugging laws of plugging-selection balls in fine profile control process of layered waterflooding wells

Comprehensive large-scale nucleic acid–testing strategies support China’s sustained containment of COVID-19

Some convergently three-term trust region conjugate gradient algorithms under gradient function non-Lipschitz continuity

Comparing watershed black locust afforestation and natural revegetation impacts on soil nitrogen on the Loess Plateau of China

Light convolutional neural network by neural architecture search and model pruning for bearing fault diagnosis and remaining useful life prediction

Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression

Dissecting the vital role of dietary changes in food security assessment under climate change

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