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Showing 1–50 of 156 results

Advanced filters: Author: Kyung Mi Woo Clear advanced filters

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.

Jae-Hyung Jin
Kyung-Tae Lee
Yong-Sun Bahn
ResearchOpen Access24 Aug 2020
Nature Communications

Volume: 11, P: 1-17
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Trichostatin A-mediated upregulation of p21^WAF1 contributes to osteoclast apoptosis

TacGhee Yi
Jeong-Hwa Baek
Kyung Mi Woo
ResearchOpen Access01 Apr 2007
Experimental & Molecular Medicine

Volume: 39, P: 213-221
Artificial intelligence for breast cancer screening in mammography (AI-STREAM): preliminary analysis of a prospective multicenter cohort study

Artificial intelligence (AI) could improve mammography screening accuracy, but prospective evidence is still lacking. Here, the authors show in a prospective multicentre cohort study under single-read settings that the diagnostic accuracy of breast radiologists can significantly improve with AI-based computer-aided detection.

Yun-Woo Chang
Jung Kyu Ryu
Kyunghwa Han
ResearchOpen Access06 Mar 2025
Nature Communications

Volume: 16, P: 1-11
Colony-stimulating factor 3 as a key mediator in the progression of idiopathic pulmonary fibrosis: a novel therapeutic target

Seungmo Kim
Yongjoong Kim
Su-Jae Lee
ResearchOpen Access02 Oct 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-13
Retroactive DNA analysis for sex determination and dystrophin gene by polymerase chain reaction with archived cytogenetic slides

Soo-Kyung Choi
Jin-Woo Kim
Song-Ro Yoon
ResearchOpen Access01 Mar 1999
Experimental & Molecular Medicine

Volume: 31, P: 36-41
Correction: Corrigendum: Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection

Young Ha Ahn
Sunyoung Park
Sunghoon Kim
Amendments and Corrections23 Jan 2017
Nature Microbiology

Volume: 2, P: 1
Spin-orbit torque-driven skyrmion dynamics revealed by time-resolved X-ray microscopy

Magnetic skyrmions are potentially suitable for future spintronic devices, but their dynamical behaviour in real space remains elusive. Here, Wooet al. report nanosecond-dynamics of a 100nm-size magnetic skyrmion triggered by current-induced spin-orbit torques.

Seonghoon Woo
Kyung Mee Song
Joonyeon Chang
ResearchOpen Access24 May 2017
Nature Communications

Volume: 8, P: 1-8
Risk of cardiovascular disease and mortality in patients with diabetes and acute pancreatitis history: a nationwide cohort study

Dong Kee Jang
Jin Ho Choi
Sang Hyub Lee
ResearchOpen Access04 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
Association of the IL16 Asn1147Lys polymorphism with intravenous immunoglobulin resistance in Kawasaki disease

Hea-Ji Kim
Jae-Jung Kim
Jong-Duk Kim
Research22 Jan 2020
Journal of Human Genetics

Volume: 65, P: 421-426
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

The genetic link between placenta function and congenital heart defects has been established, though the cellular mechanisms underlying this connection is less clear. Here they show that PIBF1 regulates syncytiotrophoblast fusion and that loss of PIBF1 also negatively impacts heart development, providing a potential link between the development of these two organs.

Jong Geol Lee
Jung-Min Yon
In-Jeoung Baek
ResearchOpen Access19 Feb 2024
Nature Communications

Volume: 15, P: 1-19
Retinoic acid inhibits inducible nitric oxide synthase expression in 3T3-L1 adipocytes

Jeong-Yeh Yang
Bon-Sun Koo
Jin-Woo Park
ResearchOpen Access01 Nov 2002
Experimental & Molecular Medicine

Volume: 34, P: 353-360
Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-XL

Kyung Mi Woo
Hyun-Man Kim
Jea Seung Ko
ResearchOpen Access01 Nov 2002
Experimental & Molecular Medicine

Volume: 34, P: 340-346
Osteoprotegerin is present on the membrane of osteoclasts isolated from mouse long bones

Kyung Mi Woo
Youngnim Choi
Kack-Kyun Kim
ResearchOpen Access01 Nov 2002
Experimental & Molecular Medicine

Volume: 34, P: 347-352
Identification of SAMD9L as a susceptibility locus for intravenous immunoglobulin resistance in Kawasaki disease by genome-wide association analysis

Jae-Jung Kim
Sin Weon Yun
Jong-Duk Kim
Research11 Apr 2019
The Pharmacogenomics Journal

Volume: 20, P: 80-86
Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study

Chung-woo Lee
Joo Kyung Lee
Joo-Hyun Park
ResearchOpen Access17 Feb 2022
Scientific Reports

Volume: 12, P: 1-9
The power of genetic diversity in genome-wide association studies of lipids

A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Research09 Dec 2021
Nature

Volume: 600, P: 675-679
Optimal time and volume of fluid resuscitation in patients with sepsis: a nationwide multicenter cohort study

Dong-gon Hyun
Jee Hwan Ahn
Hyung Koo Kang
ResearchOpen Access19 Aug 2025
Scientific Reports

Volume: 15, P: 1-11
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Increased Risk of Atrial Fibrillation and Thromboembolism in Patients with Severe Psoriasis: a Nationwide Population-based Study

Tae-Min Rhee
Ji Hyun Lee
Seil Oh
ResearchOpen Access30 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Coptidis rhizoma extract protects against cytokine-induced death of pancreatic β-cells through suppression of NF-κ B activation

Eun-Kyung Kim
Kang-Beom Kwon
Byung-Hyun Park
ResearchOpen Access01 Apr 2007
Experimental & Molecular Medicine

Volume: 39, P: 149-159
Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells

Kyung-Mi Kim
Keehyun Lee
Hae-Young Park
ResearchOpen Access01 Dec 2000
Experimental & Molecular Medicine

Volume: 32, P: 246-254
Publisher Correction: Analysis of the serial circulating tumor cell count during neoadjuvant chemotherapy in breast cancer patients

Sungchan Gwark
Jisun Kim
Sei Hyun Ahn
Amendments and CorrectionsOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1
Deep learning-based automatic segmentation of cerebral infarcts on diffusion MRI

Wi-Sun Ryu
Dawid Schellingerhout
Dong-Eog Kim
ResearchOpen Access16 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species

Doil Choi and colleagues report the genome sequence of the hot pepper, Capsicum annuum, as well as the resequencing of two cultivated peppers and a wild species, Capsicum chinense. Comparative genomic analysis across Solanaceae provides insights into genome expansion, pungency, ripening and disease resistance in hot peppers.

Seungill Kim
Minkyu Park
Doil Choi
ResearchOpen Access19 Jan 2014
Nature Genetics

Volume: 46, P: 270-278
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection

During bacterial infection, tryptophanyl-tRNA synthetase is secreted by monocytes and binds to macrophages via a TLR4–MD2 complex to induce phagocytosis and chemokine production, thereby serving as a primary defence system against infection.

Young Ha Ahn
Sunyoung Park
Sunghoon Kim
Research17 Oct 2016
Nature Microbiology

Volume: 2, P: 1-13
Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance

Here, the authors report the results of a longitudinal multi-omics trial of the use of fecal microbiota transplantation (FMT) to ameliorate diarrhea and restore gut microbial composition in 57 growing calves, and find that oral FMT induces alterations in the gut microbiota correlate with the remission of diarrhea and improves the growth performance of the cattle.

Hyun Sik Kim
Tae Woong Whon
Jin-Woo Bae
ResearchOpen Access08 Jan 2021
Nature Communications

Volume: 12, P: 1-16
Elevated troponin levels are associated with early neurological worsening in ischemic stroke with atrial fibrillation

Ki-Woong Nam
Chi Kyung Kim
Kyungmi Oh
ResearchOpen Access28 Jul 2020
Scientific Reports

Volume: 10, P: 1-7
Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea

Yeong Ho Kim
Hyun Jee Kim
Ji Hyun Lee
ResearchOpen Access26 Jul 2022
Scientific Reports

Volume: 12, P: 1-7
ANCA: artificial nucleic acid circuit with argonaute protein for one-step isothermal detection of antibiotic-resistant bacteria

Antibiotic-resistant bacteria pose a growing threat to global health. Here, the authors present an artificial nucleic acid circuit with argonaute protein (ANCA) for one-step, amplification-free, and isothermal detection of carbapenemase-producing Klebsiella pneumoniae.

Hyowon Jang
Jayeon Song
Taejoon Kang
ResearchOpen Access05 Dec 2023
Nature Communications

Volume: 14, P: 1-13
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors

Nanog can confer resistance to cancer immunotherapy by promoting AKT activity. Here, the authors demonstrate that HSP90A is a Nanog target that stabilizes the AKT coactivator TCL1, thereby activating AKT, and that HSP90A inhibition can enhance the anti-tumor efficacy of adoptive T cell transfer and checkpoint blockade.

Kwon-Ho Song
Se Jin Oh
Tae Woo Kim
ResearchOpen Access28 Jan 2020
Nature Communications

Volume: 11, P: 1-16
Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β₁ and Shh Signalling

Dong-Jin Kim
Jun Mo Kang
Sang-Ho Lee
ResearchOpen Access01 Dec 2017
Scientific Reports

Volume: 7, P: 1-13
A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes

The physiological function of TWIK-1, a two-pore K⁺ channel family member, remains unclear. Here, Hwang et al. show that TWIK-1 forms a disulphide-linked heterodimer with TREK-1 to maintain passive conductance and glutamate release in astrocytes.

Eun Mi Hwang
Eunju Kim
Jae-Yong Park
Research05 Feb 2014
Nature Communications

Volume: 5, P: 1-15
Blood viscosity associated with stroke mechanism and early neurological deterioration in middle cerebral artery atherosclerosis

Ho Geol Woo
Hyug-Gi Kim
Bum Joon Kim
ResearchOpen Access09 Jun 2023
Scientific Reports

Volume: 13, P: 1-8
Endothelial progenitor cell differentiation using cryopreserved, umbilical cord blood-derived mononuclear cells

Jun-ho Jang
Sun-kyung Kim
Hugh C Kim
Research01 Mar 2007
Acta Pharmacologica Sinica

Volume: 28, P: 367-374
Long-term air pollution exposure is associated with higher incidence of ST-elevation myocardial infarction and in-hospital cardiogenic shock

Jinah Cha
Se Yeon Choi
Myung Ho Jeong
ResearchOpen Access29 Feb 2024
Scientific Reports

Volume: 14, P: 1-9
High platelet reactivity strongly predicts early stent thrombosis in patients with drug-eluting stent implantation

Subin Lim
Soon Jun Hong
Myung Ho Jeong
ResearchOpen Access04 Jan 2024
Scientific Reports

Volume: 14, P: 1-11
Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients

While several human papilloma virus (HPV) vaccines exist, a highly effective vaccine that mediates regression of HPV-induced tumours is lacking. Here the authors show that a therapeutic DNA vaccine-induced HPV-specific polyfunctional CD8 T cell in 7 out of 9 patients who all exhibited complete regression of lesions and viral clearance.

Tae Jin Kim
Hyun-Tak Jin
Young Chul Sung
ResearchOpen Access30 Oct 2014
Nature Communications

Volume: 5, P: 1-14
Persistent proteinuria is associated with the occurrence of cardiovascular disease: a nationwide population-based cohort study

Ho Geol Woo
Moo-Seok Park
Tae-Jin Song
ResearchOpen Access25 Oct 2024
Scientific Reports

Volume: 14, P: 1-12
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Pulmonary function is influenced by environmental factors, lifestyle, and genetics. Here, in a multiethnic GWAS meta-analysis for pulmonary function traits, the authors identify over 50 additional genetic loci, a subset of which are specific for European, African, Asian, or Hispanic/Latino ancestry.

Annah B. Wyss
Tamar Sofer
Stephanie J. London
ResearchOpen Access30 Jul 2018
Nature Communications

Volume: 9, P: 1-15
The Somatic Mosaicism across Human Tissues Network

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Tim H. H. Coorens
Ji Won Oh
Yuqing Wang
Reviews02 Jul 2025
Nature

Volume: 643, P: 47-59
Up-regulation of BLT2 is critical for the survival of bladder cancer cells

Ji-Min Seo
Kyung-Jin Cho
Jae-Hong Kim
ResearchOpen Access20 Jan 2011
Experimental & Molecular Medicine

Volume: 43, P: 129-137
Development and validation of hypertension prediction models: The Korean Genome and Epidemiology Study_Cardiovascular Disease Association Study (KoGES_CAVAS)

Hyun Kyung Namgung
Hye Won Woo
Mi Kyung Kim
Research18 Feb 2022
Journal of Human Hypertension

Volume: 37, P: 205-212
Plasma amino acids and oxylipins as potential multi-biomarkers for predicting diabetic macular edema

Sang Youl Rhee
Eun Sung Jung
Choong Hwan Lee
ResearchOpen Access06 May 2021
Scientific Reports

Volume: 11, P: 1-9
False-positive results of galactomannan assays in patients administered glucose-containing solutions

Dong Woo Shin
Jungwon Cho
Kyoung-Ho Song
ResearchOpen Access31 Jan 2024
Scientific Reports

Volume: 14, P: 1-7
Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention for acute myocardial infarction with cardiogenic shock

Oh-Hyun Lee
Seok-Jae Heo
Byung Ok Kim
ResearchOpen Access01 May 2024
Scientific Reports

Volume: 14, P: 1-10
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

Oh et al. modeled age-dependent onset of Huntington’s disease by comparing reprogrammed neurons from pre-symptomatic and symptomatic patients. They found that an age-associated miRNA led to autophagy impairment and neurodegeneration.

Young Mi Oh
Seong Won Lee
Andrew S. Yoo
Research27 Oct 2022
Nature Neuroscience

Volume: 25, P: 1420-1433
Direct measurements of the colloidal Debye force

The Debye interaction is defined as the attraction between a polar molecule and a nonpolar molecule, which governs many self-assembling processes in materials. Here, Lee et al. design a like-charged colloidal model at the water-oil interface to characterize the Debye interaction for the first time.

Hyang Mi Lee
Yong Woo Kim
Bum Jun Park
ResearchOpen Access29 Jun 2023
Nature Communications

Volume: 14, P: 1-9
Chemical inhibition of prometastatic lysyl-tRNA synthetase–laminin receptor interaction

Beyond its canonical role in translation, lysyl-tRNA synthetase (KRS) stabilizes the prometastatic 67-kDa laminin receptor (67LR) in the plasma membrane. A small-molecule inhibitor of the KRS-67LR interaction modulates the KRS-promoted metastatic potential of 67LR without disrupting the normal function of each protein.

Dae Gyu Kim
Jin Young Lee
Sunghoon Kim
Research10 Nov 2013
Nature Chemical Biology

Volume: 10, P: 29-34

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