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Selecting for varieties of commercial crops with enhanced nutritional quality is important in agriculture. Here, the authors identify alleles of a gene in tomatoes that give rise to increased levels of vitamin E and find that the promoter of the gene is differentially methylated.

This study shows that many small RNAs in Capsella rubella pollen originate from maternal tissues. These mobile small RNAs support proper pollen development, revealing that non-cell-autonomous small RNAs are crucial for successful plant reproduction.

It has been suggested that strong field enhancement for high harmonic generation may be achievable with nano-antennas. Here, the authors show relevant field enhancement using a metal-sapphire nanostructure that provides a solid tip as the high harmonic emitter, replacing commonly used gaseous atoms.

Membrane ion channels can be responsive to a variety of stimuli such as pressure, temperature, or pH. Here, the authors show that simply shining 365 nm light activates a native potassium channel in rodent pain-sensing neurons, delivering powerful analgesia without drugs or genetic manipulations.

A dynamo mechanism similar to that in the Sun can produce the large-scale magnetic field that is needed to drive the relativistic outflows (and short gamma-ray burst) from binary neutron star mergers, according to a numerical relativity simulation.

Climate change threatens the future of the Antarctic Ice Sheet. Here the authors show that individual drainage basins have different thresholds and loss patterns, suggesting the need to consider the dynamical interactive nature of the basins and their individual tipping points.

Biological membranes are tightly sealed. Here, Post and Hummer capture rare lipid flip-flop events and the formation of water nanopores across lipid bilayers with AI-guided simulations. The mechanism is encoded in close-to-linear neural networks.

The integration of high-κ dielectrics with low equivalent oxide thickness (EOT) is crucial for the development of 2D transistors. Here, the authors report the low-temperature fabrication of wafer-scale HfO₂ dielectric films with sub-5-Å EOT and their application for the realization of high-performance 2D MoS₂ transistors and circuits.

Using chemical photoswitchable reagents to exert purely wavelength-dependent control over biological systems in deep tissue and in vivo requires a concentration-independent design paradigm. Here, such photoswitchable ligands are realized by ensuring that E/Z isomers have opposing efficacies yet similarly high affinity, allowing them to probe transient receptor potential C4 and C5 channel functions up to the tissue level.

The STAR experiment at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory demonstrates evidence of spin correlations in \(\Lambda \bar{\Lambda }\) hyperon pairs inherited from virtual spin-correlated strange quark–antiquark pairs during QCD confinement.

In this work, the researchers realize the current-induced motion of Néel type chiral domain walls via spin-transfer-torque in the pristine van der Waals ferromagnet Fe₃GeTe₂ and via spin-orbit-torques in heterostructures with platinum or tungsten.

Demand-side food policies show small average effects, with effectiveness varying across intervention types. Targeted strategies and a better understanding of how context and population influence outcomes can advance food system sustainability.

GIRK channels are activated by Gβγ; quantitative aspects are debatable. Here, the authors measure interaction affinities in living cell membranes and uncover roles of Gγ prenylation and a Gβγ docking site in GIRK1 in efficient channel activation.

Machine-learned force fields are becoming increasingly popular but suffer from their “black-box” nature. Here the authors adapt explainable AI techniques to coarse-grained graph neural network potentials and show that they capture physically consistent interactions.

Xeno-learning uses preclinical data from one species to boost the performance of neural networks applied to another species when exploring physiological responses.

The second plateau in high-harmonic generation from liquids is due to off-site recombination of electrons, facilitated by the spatial delocalization of electron–hole wavefunctions.

Synaptic vesicle fusion is essential for neuronal communication, yet its nanoscale sequence has not been directly confirmed. Here, the authors use timed in situ cryo-electron tomography to visualize the full fusion process and its link to vesicle resupply.

Differentiating the structural order of the commensurate modulated antiferroelectric can double the energy storage density of ceramics to over 23 J/cm³ while maintaining their efficiency.

DynamicAtlas integrates fixed and live imaging data to generate a morphodynamic atlas of Drosophila development.

2D polymer materials are often limited in performance by insufficient in-plane conjugation and poor charge transport. Guided by theoretical calculations, the authors present diketopyrrolopyrrole-based crystalline 2D poly(arylene vinylene)s with narrow optical band gaps of 1 eV and high charge carrier mobility.

Nonreciprocal photonics often relies on the use of external magnetic fields. By combining atomistic simulations based on tight-binding with a mean-field approach, here, the authors demonstrate nonreciprocal plasmon propagation in electrically biased one-dimensional carbon nanostructures, including graphene nanoribbons and carbon nanotubes.

Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and trajectories vary during health, inflammation and cancer.

Atomically thin nitrogen crystals, termed nitrogene, have been theoretically predicted, but their synthesis has remained elusive so far. Here, the authors report experimental evidence of the formation of nitrogen-based crystalline structures compatible with nitrogene on Ag(100) surfaces via ion-beam-assisted epitaxy.

Animals are often thought to follow simple alignment rules, but this study explores how collective behavior could instead emerge from neural ring-attractor networks encoding allocentric and egocentric bearings. The results show that group motion arises spontaneously when allocentric bearings are used, with rapid switching between the two representations further boosting coordination.

Radiation reaction (RR) on particles in strong fields is the subject of intense experimental research, but previous efforts lacked statistical significance due to the extreme regimes required. Here, the authors report a 5σ observation of RR and obtain strong, quantitative evidence favouring quantum models over classical, using an all-optical setup where electrons are accelerated by a laser in a gas jet before colliding with a second, intense pulse.

The common description of strong-field light–matter interaction neglects the quantum-optical nature of the driving field. Now signatures of strong-field photoemission appear in electron energy spectra when driving with non-classical light.

In this study, the authors reveal two hippocampal neuron subpopulations that encode time or distance via opposing ramping dynamics. These populations form parallel circuits controlled by distinct interneurons, PV for initiation and SST for maintenance of encoding.

The analysis of the energy spectrum of 36 million tritium β-decay electrons recorded in 259 measurement days within the last 40 eV below the endpoint challenges the Neutrino-4 claim.

iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonstrated in a variety of applications in the mouse brain.

Multicellular tissues behave akin to nematic liquid crystals, which are fluid as well as ordered. Here, the authors develop an image analysis method to capture the nematic ordering of tissues with the complex geometries typical of morphogenesis.

The effect of disorder in conventional two-dimensional electron systems is usually described in terms of individual electrons interacting with an underlying disorder potential. Scanning single-electron transistor measurements of graphene in a strong magnetic field indicate that in this system, coulombic interactions between electrons must also be taken into account.

In mice, DHPS supports the maturation, maintenance and function of tissue-resident macrophages via the polyamine–hypusine axis, with implications for macrophage-targeting therapies.

A metallic p-wave magnet with commensurate spin helix and anisotropic electronic properties is experimentally realized and shows a giant anomalous Hall effect when distorted by a tiny spontaneous magnetization.

Candida auris can scavenge carbon dioxide from microenvironments through Nce103 to sustain fitness when colonizing human skin.

The authors show that electronic thermal transport in an in-plane magnetic field in compressively strained HgTe at the Weyl points follows the Wiedemann–Franz law, challenging predictions of gravitational-anomaly signatures in this system.

Observed 730 Myr after the Big Bang, a little red dot is found to anchor an overdensity of eight galaxies and seems to be embedded in a massive host dark matter halo.

Several recent publications have attempted to detect novel unannotated microproteins using mass spectrometry proteomics. Here, the authors reassess these claimed microprotein detections, finding that many are poorly supported, while a subset represents likely genuine discoveries of novel proteins.

The cytoplasm can be partitioned into distinct compartments by microtubule structures, which can be stabilized by distinct mechanisms in different species.

Global Burden of Disease estimates show that between 1990 and 2023, the prevalence and burden of drug use disorders, inclusive of amphetamine, cannabis, cocaine and opioid use, have been increasing in high-income countries, particularly in the USA.

New hominin fossils from the Grotte à Hominidés at Thomas Quarry I (ThI-GH) in Casablanca, Morocco, dated to around 773 thousand years ago are similar in age to Homo antecessor, yet are morphologically distinct.

A large sulfur-bearing carbon ring molecule has been detected in space, 2,5-cyclohexadien-1-thione, using laboratory spectroscopy and a radio telescope. Found near the Galactic Centre, it opens the door to a new family of interstellar molecules.

SimuFLUX, a user-friendly simulator, accepts commercial MINFLUX microscope configuration files and implements detailed models of point spread functions, fluorophore dynamics, and optical mechanics to optimize and assess feasibility of MINFLUX experiments.

A plasma lens capable of focusing broadband extreme-ultraviolet attosecond pulses is demonstrated.