Nature Search

Natural habitat of coelacanths

HANS FRICKE
KAREN HISSMANN
Research26 Jul 1990
Nature

Volume: 346, P: 323-324
Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspring

The treatment potential of psilocybin for postpartum depression was investigated in a preclinical mouse model. Here the authors show both acute and long-term effects of psilocybin in mothers and their offspring who were exposed via lactation.

Cassandra J. Hatzipantelis
Min Liu
Danielle S. Stolzenberg
ResearchOpen Access30 Sept 2025
Nature Communications

Volume: 16, P: 1-15
Isoprene chemistry under upper-tropospheric conditions

Experiments under upper-tropospheric conditions map the chemical formation of isoprene oxygenated organic molecules (important molecules for new particle formation) and reveal that relative radical ratios control their composition

Douglas M. Russell
Felix Kunkler
Joachim Curtius
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Cryptic variation in vulva development by cis-regulatory evolution of a HAIRY-binding site

Robustness to mutations can give rise to cryptic variation —a bottled-up genetic potential, which is of undetermined importance in developmental processes. Kienle and Sommer show the occurrence of cryptic variation in nematode vulva development and identify cis-regulatory evolution of the transcription factor’s HAIRY-binding site as mechanism.

Simone Kienle
Ralf J. Sommer
Research16 Apr 2013
Nature Communications

Volume: 4, P: 1-8
Proteomics and constraint-based modelling reveal enzyme kinetic properties of Chlamydomonas reinhardtii on a genome scale

Closing a major gap in photosynthetic metabolic modelling, the authors provide over 500 estimates of in vivo enzyme catalytic rate in C. reinhardtii, which considerably improves predictions on how enzyme mass is allocated to different pathways.

Marius Arend
David Zimmer
Zoran Nikoloski
ResearchOpen Access08 Aug 2023
Nature Communications

Volume: 14, P: 1-9
Magnon-polarons in the Fermi–Hubbard model

In strongly correlated systems, how magnetic excitations are renormalized by charge carriers remains an open question. An experiment now reports the observation of magnon-polarons—magnons dressed by doped holes—in a Fermi–Hubbard quantum simulator.

Max L. Prichard
Zengli Ba
Waseem S. Bakr
Research22 Aug 2025
Nature Physics

P: 1-7
Microbiota succession influences nematode physiology in a beetle microcosm ecosystem

This study uses decomposing beetle grubs to replicate the natural microbial habitat of a nematode model organism. The approach enables exploration of interactions between nematodes and their microbiota and was used to show the importance of microbial successions and their reciprocal interaction with nematodes for insect decay.

Wen-Sui Lo
Ralf J. Sommer
Ziduan Han
ResearchOpen Access15 Jun 2024
Nature Communications

Volume: 15, P: 1-11
Probing condensate microenvironments with a micropeptide killswitch

Targeting a non-natural micropeptide ‘killswitch’ to several biomolecular condensates altered condensate compositions and revealed condensate functions in human cells

Yaotian Zhang
Ida Stöppelkamp
Denes Hnisz
ResearchOpen Access04 Jun 2025
Nature

Volume: 643, P: 1107-1116
Mechanistic resource competition theory applied to laboratory experiments with zooplankton

Karl O. Rothhaupt
Research16 Jun 1988
Nature

Volume: 333, P: 660-662
Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates

The conserved eukaryotic heterotrimeric NatC complex co-translationally acetylates the N-termini of numerous target proteins. Here, the authors provide insights into the catalytic mechanism of NatC by determining the crystal structures of Saccharomyces cerevisiae NatC in the absence and presence of cofactors and peptide substrates and reveal the molecular basis of substrate binding by further biochemical analyses.

Stephan Grunwald
Linus V. M. Hopf
Oliver Daumke
ResearchOpen Access02 Nov 2020
Nature Communications

Volume: 11, P: 1-14
NAD⁺ metabolism is a key modulator of bacterial respiratory epithelial infections

Streptococcus pneumoniae is a common cause of lower respiratory tract infection. Here, Klabunde et al. present a transcriptomic, metabolomic and proteomic characterisation of the bronchial epithelial cell response to infection and show that NAD⁺ has a role in controlling bacterial replication.

Björn Klabunde
André Wesener
Bernd Schmeck
ResearchOpen Access02 Oct 2023
Nature Communications

Volume: 14, P: 1-16
Functional divergence of conserved developmental plasticity genes between two distantly related nematodes

Sara Wighard
Hanh Witte
Ralf J. Sommer
ResearchOpen Access05 Aug 2025
Scientific Reports

Volume: 15, P: 1-12
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis

Hegazy and colleagues demonstrate that epithelial oncostatin M receptor expression drives gut inflammation and tumor formation.

Roodline Cineus
Yanjiang Luo
Ahmed N. Hegazy
ResearchOpen Access30 May 2025
Nature Immunology

Volume: 26, P: 837-853
The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism

Ralf Sommer and colleagues present a draft genome sequence of the nematode Pristionchus pacificus, a species that lives in association with beetles and shows a major expansion of protein-coding genes. Comparative analysis with the genomes of the ecologically distinct nematodes C. elegans and B. malayi suggests insights into the association between their genome structures and differing lifestyles.

Christoph Dieterich
Sandra W Clifton
Ralf J Sommer
Research21 Sept 2008
Nature Genetics

Volume: 40, P: 1193-1198
A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum

Thomas Sommer
Stefan Jentsch
Research09 Sept 1993
Nature

Volume: 365, P: 176-179
Detection of a γ-ray burst of very long duration and very high energy

K. Hurley
B. L. Dingus
M. Niel
Research15 Dec 1994
Nature

Volume: 372, P: 652-654
An everlasting pioneer: the story of Antirrhinum research

Zsuzsanna Schwarz-Sommer
Brendan Davies
Andrew Hudson
Reviews01 Aug 2003
Nature Reviews Genetics

Volume: 4, P: 655-664
Histone 4 lysine 5/12 acetylation enables developmental plasticity of Pristionchus mouth form

Developmental plasticity allows organisms to match traits to their environment, however, there are few known molecular mechanisms underlying such plasticity. Here, the authors show that feeding morphs in adult Pristionchus nematodes are set during a critical window in juveniles and identify H4K5/12ac as the environmental information carrier.

Michael S. Werner
Tobias Loschko
Ralf J. Sommer
ResearchOpen Access13 Apr 2023
Nature Communications

Volume: 14, P: 1-14
Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice

A multi-omics approach reveals host–microbiome interactions in aging in mice.

Lena Best
Thomas Dost
Christoph Kaleta
ResearchOpen Access26 Mar 2025
Nature Microbiology

Volume: 10, P: 973-991
Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells

Kinase inhibitors are key in cancer therapy, but resistance limits their efficacy. Here, the authors develop SPIED-DIA, a phosphoproteomics method enhancing detection of key phosphorylation sites. They reveal a synergistic MEK-JNK signaling response in colorectal cancer cells, suggesting a potential therapeutic strategy.

Mirjam van Bentum
Bertram Klinger
Matthias Selbach
ResearchOpen Access27 May 2025
Nature Communications

Volume: 16, P: 1-16
Strontium isoscape of sub-Saharan Africa allows tracing origins of victims of the transatlantic slave trade

Strontium isotope analysis can be applied to animal and plant tissues to help determine their provenance. Here, the authors generate a strontium isoscape of sub-Saharan Africa using data from 2266 environmental samples and demonstrate its efficacy by tracing the African roots of individuals from historic slavery contexts.

Xueye Wang
Gaëlle Bocksberger
Vicky M. Oelze
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-14
Sp1/egr-like zinc-finger protein required for endoderm specification and germ-layer formation in Drosophila

Günter Brönner
Quynh Chu-LaGraff
Herbert Jäckle
Research23 Jun 1994
Nature

Volume: 369, P: 664-668
Adenovirally transferred p16^INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

Volker Sandig
Karsten Brand
Michael Strauss
Research01 Mar 1997
Nature Medicine

Volume: 3, P: 313-319
The hard X-ray spectrum of Cyg X-1 during the transition in November 1975

M. SOMMER
H. MAURUS
R. URBACH
Research28 Oct 1976
Nature

Volume: 263, P: 752-753
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48

Ernst Jarosch
Christof Taxis
Thomas Sommer
Research28 Jan 2002
Nature Cell Biology

Volume: 4, P: 134-139
Implications for trace gases and aerosols of large negative ion clusters in the stratosphere

F. Arnold
A. A. Viggiano
H. Schlager
Research03 Jun 1982
Nature

Volume: 297, P: 371-376
A large dust/ice ratio in the nucleus of comet 9P/Tempel 1

Michael Küppers
Ivano Bertini
Rafael Rodrigo
Research13 Oct 2005
Nature

Volume: 437, P: 987-990
Rapid chromosome evolution and acquisition of thermosensitive stochastic sex determination in nematode androdioecious hermaphrodites

Sexual systems evolve frequently in nematodes. Through large-scale genomic analyses, Yoshida et al. find rapid chromosome evolution, sex chromosome turnover and acquisition of stochastic sex determination, are involved in sexual system evolution of Pristionchus nematodes.

Kohta Yoshida
Hanh Witte
Ralf J. Sommer
ResearchOpen Access07 Nov 2024
Nature Communications

Volume: 15, P: 1-15
De novo protein-coding gene variants in developmental stuttering

Else Eising
Ivana Dzinovic
Simon E. Fisher
ResearchOpen Access20 Aug 2025
Molecular Psychiatry

P: 1-12
Biosynthesis of modular signaling molecules requires functional diversification of carboxylesterases in Pristionchus pacificus

A systematic screening of biosynthetic genes largely clarifies the intricate biosynthetic mechanisms by which diversification of carboxylesterases generates a complex blend of modular signaling pheromones in Pristionchus pacificus.

Pei Zhang
Penghieng Theam
Chuanfu Dong
ResearchOpen Access13 Aug 2025
Communications Biology

Volume: 8, P: 1-11
Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and understand such antibiotic relationships.

Nazgul Sakenova
Elisabetta Cacace
Athanasios Typas
ResearchOpen Access02 Dec 2024
Nature Microbiology

Volume: 10, P: 202-216
Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension

Khassafi et al. identify molecular subgroups of right ventricular (RV) dysfunction using transcriptomic analysis of RV samples from individuals with compensated RV hypertrophy or decompensated RV failure and two rat models of RV dysfunction. Several extracellular matrix genes found to be deregulated in decompensated RV subgroups were validated at the protein level in two independent cohorts of individuals with pulmonary arterial hypertension, revealing their predictive biomarker potential in maladaptive RV development.

Fatemeh Khassafi
Prakash Chelladurai
Soni Savai Pullamsetti
ResearchOpen Access28 Sept 2023
Nature Cardiovascular Research

Volume: 2, P: 917-936
Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

Wolfgang Seufert
Bruce Futcher
Stefan Jentsch
Research05 Jan 1995
Nature

Volume: 373, P: 78-81
Pulsed high-energy γ-rays from the radio pulsar PSRI706–44

D. J. Thompson
Z. Arzoumanian
J. H. Taylor
Research15 Oct 1992
Nature

Volume: 359, P: 615-616
A regulatory link between ER-associated protein degradation and the unfolded-protein response.

Ruth Friedlander
Ernst Jarosch
Thomas Sommer
Research23 May 2000
Nature Cell Biology

Volume: 2, P: 379-384
Late Proterozoic rise in atmospheric oxygen concentration inferred from phylogenetic and sulphur-isotope studies

Donald E. Canfield
Andreas Teske
Research11 Jul 1996
Nature

Volume: 382, P: 127-132
A new petunia flower colour generated by transformation of a mutant with a maize gene

Peter Meyer
Iris Heidmann
Heinz Saedler
Research23 Dec 1987
Nature

Volume: 330, P: 677-678
A wax ester promotes collective host finding in the nematode Pristionchus pacificus

Nematodes are known to stand on their tails and wave—a process called nictation—in an effort to find a new host. Studies of Pristionchus pacificus now show these worms can aggregate to nictate collectively, mediated by the newly discovered natural lipid, nematoil.

Sider Penkov
Akira Ogawa
Teymuras V Kurzchalia
Research02 Mar 2014
Nature Chemical Biology

Volume: 10, P: 281-285
Distance limit for a class of model γ-ray burst sources

WOLFGANG K.H. SCHMIDT
Research01 Feb 1978
Nature

Volume: 271, P: 525-527
Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases

Genetically engineered mice are an important aspect of human disease research. Here, the authors use artificial transcription activator-like effector-nucleases to generate a mouse line with a conditionally targeted allele and suggest that this method can be easily adapted to any gene in the mouse genome.

Daniel Sommer
Annika E. Peters
Marc Beyer
Research13 Jan 2014
Nature Communications

Volume: 5, P: 1-12
Whole-brain annotation and multi-connectome cell typing of Drosophila

A consensus cell type atlas for the fly brain provides both an intellectual framework and open-source toolchains for brain-scale comparative connectomics.

Philipp Schlegel
Yijie Yin
Gregory S. X. E. Jefferis
ResearchOpen Access02 Oct 2024
Nature

Volume: 634, P: 139-152
Pathogen-associated selection on innate immunity genes (TLR4, TLR7) in a neotropical rodent in landscapes differing in anthropogenic disturbance

Alexander Christoph Heni
Julian Schmid
Simone Sommer
ResearchOpen Access02 Jul 2020
Heredity

Volume: 125, P: 184-199
Augmentation of lymphocyte reactivity in guinea pigs, mice, monkeys and humans sensitised to BCG, dinitrochlorobenzene or nitrogen mustard

MAX H. COHEN
PAUL B. CHRETIEN
AYUB K. OMMAYA
Research14 Jun 1974
Nature

Volume: 249, P: 656-658
Unveiling the structure, function and dynamics of StmPr1 in Stenotrophomonas maltophilia virulence

Max Sommer
Amr Negm
Christian Betzel
ResearchOpen Access20 Jun 2025
Scientific Reports

Volume: 15, P: 1-15
Attosecond nonlinear polarization and light–matter energy transfer in solids

Petahertz-bandwidth metrology is demonstrated in the measurement of nonlinear polarization in silica.

A. Sommer
E. M. Bothschafter
F. Krausz
Research23 May 2016
Nature

Volume: 534, P: 86-90
Syntaxin specificity of cytokinesis in Arabidopsis

Isabel Müller
Wenke Wagner
Gerd Jürgens
Research12 May 2003
Nature Cell Biology

Volume: 5, P: 531-534
Senescence-associated lineage-aberrant plasticity evokes T-cell-mediated tumor control

Cellular senescence plays a crucial role in cancer therapy, influencing how tumours respond to treatment. Here, the authors show that therapy-induced senescence in B-cell lymphoma leads to myeloid-like plasticity, enhancing T-cell recognition and improving patient outcomes.

Dimitri Belenki
Paulina Richter-Pechanska
Clemens A. Schmitt
ResearchOpen Access31 Mar 2025
Nature Communications

Volume: 16, P: 1-20
Similarity of the Cin1 repetitive family of Zea mays to eukaryotic transposable elements

Nancy S. Shepherd
Zsuzsanna Schwarz-Sommer
Heinz Saedler
Research12 Jan 1984
Nature

Volume: 307, P: 185-187
Evolutionary conservation of components of the protein translocation complex

Enno Hartmann
Thomas Sommer
Tom A. Rapoport
Research17 Feb 1994
Nature

Volume: 367, P: 654-657
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity

Formaldehyde (FA) is known to exert cytotoxicity through DNA damage. Here, the authors show that FA also triggers cellular redox imbalance by reacting with glutathione (GSH), and that FA cytotoxicity is prevented by GSH synthesis and by ADH5, an enzyme that metabolizes FA-GSH products.

Carla Umansky
Agustín E. Morellato
Lucas B. Pontel
ResearchOpen Access08 Feb 2022
Nature Communications

Volume: 13, P: 1-15

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