Nature Search

Genome-wide association study provides insights into the genetic basis of Lewy body dementia

Ping Zhu
Zhengxin Jin
Guiyou Liu
Research09 Oct 2025
Molecular Psychiatry

P: 1-15
Neoadjuvant ARX788 plus pyrotinib versus trastuzumab, pertuzumab, docetaxel and carboplatin for HER2-positive breast cancer: a randomised phase 2b trial

Combining antibody drug conjugates (ADCs) and tyrosine kinase inhibitors (TKIs) targeting HER2 has been shown to improve efficacy in patients with advanced HER2+ breast cancer. Here, the authors report a randomised phase 2b trial comparing neoadjuvant ARX788 (HER2 ADC) plus pyrotinib (HER1, HER2 and HER4 TKI) against neoadjuvant standard of care (docetaxel, carboplatin, trastuzumab, and pertuzumab) for the treatment of HER2+ breast cancer.

Nan Niu
Jinqi Xue
Caigang Liu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-9
Machine learning-assisted Ru-N bond regulation for ammonia synthesis

Developing Ru-intermetallic catalysts for mild ammonia synthesis faces structural complexity. Here, machine learning identified Sc_1/8Nd_7/8Ru₂, optimizing Ru–N bonding and orbital hybridization, enhancing catalytic activity under mild conditions.

Zichuang Li
Mingxin Zhang
Tian-Nan Ye
ResearchOpen Access21 Aug 2025
Nature Communications

Volume: 16, P: 1-11
Sex-specific impact of mild obesity on the prognosis of ST-segment elevation myocardial infarction

Lingling Zhang
Zhican Liu
Mingxin Wu
ResearchOpen Access26 Jan 2024
Scientific Reports

Volume: 14, P: 1-9
Efficacy of combined TAE, HAIC, targeted, and immunotherapy in unresectable HCC: a multicenter propensity score matching study

Cheng Zhang
Yuyan Xu
Mingxin Pan
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study

Scavenger receptor-A (SR-A) is mostly expressed by myeloid cells and has been attributed a variety of biological functions. Here the authors assess SR-A as a biomarker for diagnosis of rheumatoid arthritis (RA) using large-scale training and validation cohorts and show that modulating SR-A levels can alter progression of collagen-induced arthritis in mice.

Fanlei Hu
Xiang Jiang
Zhanguo Li
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-14
Quantification of diaphragmatic dynamic dysfunction in septic patients by bedside ultrasound

Yunqiu Chen
Yujia Liu
Guangyu Jiao
ResearchOpen Access15 Oct 2022
Scientific Reports

Volume: 12, P: 1-8
Long-term impact of air pollution on heart failure readmission in unstable angina patients

Lingling Zhang
Zhican Liu
Mingyan Jiang
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-12
Cortical thickness deviations as biomarker for subtyping and prognosis in pediatric brainstem tumors

Heyuan Jia
Kaikai Wang
Liwei Zhang
ResearchOpen Access16 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Proteomics-driven noninvasive screening of circulating serum protein panels for the early diagnosis of hepatocellular carcinoma

Hepatocellular carcinoma is often diagnosed at a late stage which limits treatment efficacy. Here, the authors utilise proteomics to identify serum proteomic biomarkers for early diagnosis, and validate using a prospective validation cohort.

Xiaohua Xing
Linsheng Cai
Xiaolong Liu
ResearchOpen Access18 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Spatio-temporal evolution and coupling relationship between biodiversity and urbanization in the areas along the Yellow River of Shandong province

Yingjun Sun
Wenxue Meng
Zhen Jian
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-20
Comparative efficacy, safety, and tolerability of pharmacotherapies for acute mania in adults: a systematic review and network meta-analysis of randomized controlled trials

Wenbo Huang
Shuyang He
Jilai Xu
Research27 Aug 2024
Molecular Psychiatry

Volume: 30, P: 838-847
Cathepsin F and Fibulin-1 as novel diagnostic biomarkers for brain metastasis of non-small cell lung cancer

Song Wei
Wenwen Liu
Qi Wang
ResearchOpen Access25 Feb 2022
British Journal of Cancer

Volume: 126, P: 1795-1805
Sex differences in patients with heart failure and mildly reduced left ventricular ejection fraction

Zhican Liu
Yunlong Zhu
Jianping Zeng
ResearchOpen Access26 Apr 2023
Scientific Reports

Volume: 13, P: 1-10
Molecular classification of hormone receptor-positive /HER2-positive breast cancer reveals potential neoadjuvant therapeutic strategies

Chao Liu
Lisha Sun
Caigang Liu
ResearchOpen Access26 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-12
Individualized cerebellar damage predicts the presence of behavioral disorders in children with brainstem tumors

Jia et al. employ a normative model to identify cerebellar damage patterns in children with brainstem tumors. Machine learning reveals that individualized cerebellar deviations predict social problems and withdrawn behaviours in these patients.

Heyuan Jia
Kaikai Wang
Liwei Zhang
ResearchOpen Access25 Mar 2025
Communications Medicine

Volume: 5, P: 1-10
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC

Guanghui Zhang
Qingzong Zhu
Hongjuan Cui
ResearchOpen Access09 Apr 2022
Cell Death Discovery

Volume: 8, P: 1-10
Seasonal characteristics of nosocomial infection in a psychiatric hospital in China with different nosocomial prevention and control backgrounds: a retrospective study

Yufang Zhou
Shuili Chen
Xing Zheng
ResearchOpen Access24 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Corilagin enhances the anti-tumor activity of 5-FU by downregulating the expression of GRP 78

Simin Li
Xinquan Li
Qiang Wang
ResearchOpen Access19 Dec 2023
Scientific Reports

Volume: 13, P: 1-14
Serum micro-RNAs with mutation-targeted RNA modification: a potent cancer detection tool constructed using an optimized machine learning workflow

Wei Liao
Yuyan Xu
Huanwei Chen
ResearchOpen Access19 Apr 2024
Scientific Reports

Volume: 14, P: 1-11
Expression of SARS-CoV-2 entry receptor ACE2 in human brain and its association with Alzheimer’s disease and COVID-19

Sijie Li
Jingyi Sun
Guiyou Liu
Reviews06 Apr 2025
Molecular Psychiatry

Volume: 30, P: 3257-3268
A N7-methylguanosine modified circular RNA, circIPP2A2, promotes malignant behaviors in hepatocellular carcinoma by serving as a scaffold in modulating the Hornerin/PI3K/AKT/GSK3β axis

Zeyi Guo
Zhongzhe Li
Shunjun Fu
ResearchOpen Access30 Nov 2024
Cell Death & Disease

Volume: 15, P: 1-14
Repeated use of SSRIs potentially associated with an increase on serum CK and CK-MB in patients with major depressive disorder: a retrospective study

Shengwei Wu
Yufang Zhou
Lin Yu
ResearchOpen Access28 Jun 2021
Scientific Reports

Volume: 11, P: 1-8
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway

Mingxin Ci
Gaichao Zhao
Hongjuan Cui
ResearchOpen Access01 Mar 2024
Cell Death & Disease

Volume: 15, P: 1-11
Regulation of HNRNP family by post-translational modifications in cancer

Bohao Li
Mingxin Wen
Yangmiao Duan
ReviewsOpen Access04 Oct 2024
Cell Death Discovery

Volume: 10, P: 1-16
Tumor irradiation followed by intratumoral cytokine gene therapy for murine renal adenocarcinoma

Gilda G Hillman
Philippe Slos
Jeffrey D Forman
Research18 Dec 2003
Cancer Gene Therapy

Volume: 11, P: 61-72

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