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Scientific Reports (24)
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Showing 1–50 of 55 results

Advanced filters: Author: Minyoung E. Kim Clear advanced filters

Whole-genome sequencing analyses suggest novel genetic factors associated with Alzheimer’s disease and a cumulative effects model for risk liability

Here the authors reveal via whole genome sequencing of an East Asian AD cohort a common variant locus (APCDD1), rare noncoding variants in excitatory neurons, and short tandem repeat expansions, suggesting a cumulative effects model for Alzheimer’s risk.

Jun Pyo Kim
Minyoung Cho
Hong-Hee Won
ResearchOpen Access26 May 2025
Nature Communications

Volume: 16, P: 1-18
A blueprint for broadly effective bacteriophage-antibiotic cocktails against bacterial infections

The application of phage therapy for multidrug-resistant infections is mainly limited to personalized therapy due to the narrow host range of individual phages. Here, Kim et al. identify groups of phages that use non-redundant receptors, and present a blueprint for the development of effective, broad-spectrum phage-antibiotic combinations.

Minyoung Kevin Kim
Qingquan Chen
Paul L. Bollyky
ResearchOpen Access28 Nov 2024
Nature Communications

Volume: 15, P: 1-15
Engineered Sdd7 cytosine base editors with enhanced specificity

CRISPR base editors enable precise DNA changes but often cause off-target edits. Here, authors engineer two Sdd7 variants that minimize bystander and off-target mutations and show enhanced precision when delivered as ribonucleoproteins via engineered virus-like particles.

Hye-Yeon Hwang
Minyoung Lee
Daesik Kim
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Cross-ancestry genome-wide association study identifies implications of SORL1 in cerebral beta-amyloid deposition

A cross-ancestry GWAS meta-analysis of β-amyloid deposition in East Asian and European populations identifies a novel SORL1 locus and highlights its differential expression in microglia associated with β-amyloid positivity.

Jun Pyo Kim
Sang-Hyuk Jung
Hong-Hee Won
ResearchOpen Access02 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Time-resolved Brownian tomography of single nanocrystals in liquid during oxidative etching

Atomic structural changes in nanocrystals are still poorly understood. Here, the authors introduce time-resolved Brownian tomography to directly detect 3D atomic changes in Pt nanocrystals during oxidative etching and reveal disorder at sizes of ≈1 nm.

Sungsu Kang
Joodeok Kim
Jungwon Park
ResearchOpen Access29 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Mapping and annotating genomic loci to prioritize genes and implicate distinct polygenic adaptations for skin color

Here, the authors perform a large GWAS for objectively quantified skin color in an East Asian population (N = 48,433), identifying potential causal genes, polygenic adaptations, and interaction between genetic variants and sun-exposure at polygenic level.

Beomsu Kim
Dan Say Kim
Hong-Hee Won
ResearchOpen Access07 Jun 2024
Nature Communications

Volume: 15, P: 1-16
Electroconvective viscous fingering in a single polyelectrolyte fluid on a charge selective surface

When a low-viscosity fluid displaces into a higher viscosity fluid, the liquid-liquid interface becomes unstable causing finger-like patterns. These patterns are usually observed in two fluids, but here Kim et al. describes the development of fingers in a single polyelectrolyte fluid adjacent to a charge-selective interface under the influence of a potential gradient.

Jeonghwan Kim
Joonhyeon Kim
Rhokyun Kwak
ResearchOpen Access17 Nov 2023
Nature Communications

Volume: 14, P: 1-9
Unraveling oxygen vacancy-driven catalytic selectivity and hot electron generation on heterointerfaces using nanostructured platform

Tuning the physicochemical properties of oxides is essential for achieving efficient and selective reactions in heterogeneous catalysis, yet their precise catalytic role remains unclear. Here, the authors present a model platform featuring well-aligned CeOx nanowire arrays on Pt catalysts, enabling a systematic investigation of their catalytic function.

Gyu Rac Lee
Kyoungjae Song
Jeong Young Park
ResearchOpen Access25 Mar 2025
Nature Communications

Volume: 16, P: 1-12
Uniform volumetric single-cell processing for organ-scale molecular phenotyping

An ultra-rapid 3D immunostaining protocol can uniformly label organ-scale tissues.

Dae Hee Yun
Young-Gyun Park
Kwanghun Chung
Research24 Jan 2025
Nature Biotechnology

P: 1-12
Single-cell ultra-high-throughput multiplexed chromatin and RNA profiling reveals gene regulatory dynamics

This work presents SUM-seq, an ultra-high-throughput method for co-profiling chromatin accessibility and gene expression in single nuclei across multiplexed samples, advancing the study of gene regulation in diverse biological systems.

Sara Lobato-Moreno
Umut Yildiz
Judith B. Zaugg
ResearchOpen Access26 May 2025
Nature Methods

Volume: 22, P: 1213-1225
Targeting TGF-β–Smad2/3–JNK1-mediated SIRT1 activity overcomes the chemoresistance of KRAS mutation lung cancer

Dong Hoon Shin
Minyoung Choi
Sang Soo Kim
ResearchOpen Access12 Sept 2025
Experimental & Molecular Medicine

Volume: 57, P: 2022-2039
Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development

Covalent attachment of quorum-modulating peptides to surfaces can regulate Staphyloccocus aureus biofilm formation.

Minyoung Kevin Kim
Aishan Zhao
Bonnie L. Bassler
Research22 May 2017
Nature Microbiology

Volume: 2, P: 1-12
SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

SGLT2 inhibitors, a class of type 2 diabetes medication, reduce cardiovascular events in patients beyond expectation from blood sugar control. Here the authors report a randomized controlled trial showing that SGLT2 inhibitors reduce inflammasome activation in peripheral macrophages, which may contribute to the cardiovascular protection.

So Ra Kim
Sang-Guk Lee
Yong-ho Lee
ResearchOpen Access01 May 2020
Nature Communications

Volume: 11, P: 1-11
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions

Where memories are located in our brains is not well understood. In this paper, the authors demonstrate that memories are spread out throughout multiple brain regions.

Dheeraj S. Roy
Young-Gyun Park
Susumu Tonegawa
ResearchOpen Access04 Apr 2022
Nature Communications

Volume: 13, P: 1-16
Observing growth and interfacial dynamics of nanocrystalline ice in thin amorphous ice films

In-situ cryo-electron microscopy in thin amorphous ice films and ice-dynamics simulations reveal polymorph-dependent growth kinetics of nanoscale ice crystals. Hetero-crystalline ice exhibits anisotropic growth: fast-growing facets are associated with low-density interfaces, driving tetrahedral ordering of interfacial H₂O molecules and accelerating ice growth.

Minyoung Lee
Sang Yup Lee
Dong June Ahn
ResearchOpen Access30 Jan 2024
Nature Communications

Volume: 15, P: 1-13
TAPE-seq is a cell-based method for predicting genome-wide off-target effects of prime editor

Methods to predict genome-wide off-target activities of prime editors (PEs) are currently lacking. Here the authors report a cell-based assay, TAgmentation of Prime Editor sequencing (TAPE-seq), that provides genome-wide off-target candidates for PEs.

Jeonghun Kwon
Minyoung Kim
Jungjoon K. Lee
ResearchOpen Access29 Dec 2022
Nature Communications

Volume: 13, P: 1-13
RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia

Secondary acute myeloid leukemias (sAMLs) evolving from myeloproliferative neoplasms (MPNs) associate with poor prognosis. Here authors identify RSK1 as a vulnerability for MPN and sAML and show the efficacy of a first-in-class RSK inhibitor, PMD-026, against these types of myeloid malignancies.

Tim Kong
Angelo B. A. Laranjeira
Stephen T. Oh
ResearchOpen Access16 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Origin of macroscopic adhesion in organic light-emitting diodes analyzed at different length scales

Sungho Kim
Seongjae Park
Yunseok Kim
ResearchOpen Access23 Apr 2018
Scientific Reports

Volume: 8, P: 1-7
Association between body fat and bone mineral density in Korean adults: a cohort study

Hyunjung Yoon
Eunju Sung
Sujeong Shin
ResearchOpen Access14 Oct 2023
Scientific Reports

Volume: 13, P: 1-7
Local and global consequences of flow on bacterial quorum sensing

Quorum sensing (QS) systems in bacteria coordinate collective behaviour through the use of secreted signal molecules called autoinducers. Here, the authors identify conditions under which flow can activate or repress QS in S. aureus and V. cholera.

Minyoung Kevin Kim
François Ingremeau
Howard A. Stone
Research11 Jan 2016
Nature Microbiology

Volume: 1, P: 1-5
Fabrication of phosphor in glass using waste glass for automotive lighting application

Seung Hee Choi
Seok Bin Kwon
Young Hyun Song
ResearchOpen Access17 Mar 2023
Scientific Reports

Volume: 13, P: 1-8
The relationship between nest location selection of Barn swallows (Hirundo rustica) and human activity and residence

Minyoung Kim
Ok-Sik Chung
Jong Koo Lee
ResearchOpen Access27 Dec 2023
Scientific Reports

Volume: 13, P: 1-8
Diagnostic accuracy of ¹⁸F-FP-CIT PET for clinically uncertain Parkinsonian syndrome

Minyoung Oh
Seung Jun Oh
Jae Seung Kim
ResearchOpen Access12 Sept 2023
Scientific Reports

Volume: 13, P: 1-7
Association between pancreatic fibrosis and development of pancreoprivic diabetes after pancreaticoduodenectomy

Jung Min Lee
Hyung Sun Kim
Joon Seong Park
ResearchOpen Access07 Dec 2021
Scientific Reports

Volume: 11, P: 1-8
Association between low fasting glucose of the living donor and risk of graft loss in the recipient after liver transplantation

Hwa-Hee Koh
Minyoung Lee
Deok-Gie Kim
ResearchOpen Access06 Jan 2025
Scientific Reports

Volume: 15, P: 1-9
Comparative analysis of body composition using torso CT from PET/CT with bioelectrical impedance and muscle strength in healthy adults

Dong Yun Lee
Jungsu S. Oh
Jin-Sook Ryu
ResearchOpen Access16 Sept 2024
Scientific Reports

Volume: 14, P: 1-13
Comorbidity index for predicting mortality at 6 months after reperfusion therapy

Hyo Suk Nam
Young Dae Kim
Ji Hoe Heo
ResearchOpen Access16 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
Self-interest overrides rank-reversal aversion in resource distribution

Minyoung Kim
Kun Il Kim
Hackjin Kim
ResearchOpen Access24 Aug 2024
Scientific Reports

Volume: 14, P: 1-10
A shared aperture multiport antenna for rural wireless communication and safety monitoring using TVWS, ISM, and 5G mmWave bands

Md Abu Sufian
Sang-Min Lee
Nam Kim
ResearchOpen Access18 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

Haiying Zhang
Hyeok Kim
Young-Guen Kwon
ResearchOpen Access07 Jan 2022
Experimental & Molecular Medicine

Volume: 54, P: 23-34
Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer

Dong Hoon Shin
Jeong Yeon Jo
Sang Soo Kim
ResearchOpen Access02 Oct 2023
Experimental & Molecular Medicine

Volume: 55, P: 2220-2237
FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation

Yan-Hong Cui
Hyeonmi Kim
Su-Jae Lee
Research04 Jul 2018
Oncogene

Volume: 37, P: 5794-5809
Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus

Hannah Seok
Minyoung Lee
Bong Soo Cha
ResearchOpen Access13 Mar 2019
Scientific Reports

Volume: 9, P: 1-10
Comparative evaluation of Nanopore polishing tools for microbial genome assembly and polishing strategies for downstream analysis

Jin Young Lee
Minyoung Kong
Woori Kwak
ResearchOpen Access20 Oct 2021
Scientific Reports

Volume: 11, P: 1-11
Effects of heavy metal exposure during pregnancy on birth outcomes

Sabrina Shafi Zinia
Ki-Hyeok Yang
Chang Sun Sim
ResearchOpen Access03 Nov 2023
Scientific Reports

Volume: 13, P: 1-10
Temperature-dependent competitive advantages of an allelopathic alga over non-allelopathic alga are altered by pollutants and initial algal abundance levels

Yongeun Kim
Jino Son
Kijong Cho
ResearchOpen Access10 Mar 2020
Scientific Reports

Volume: 10, P: 1-13
Therapeutic mechanism of cord blood mononuclear cells via the IL-8-mediated angiogenic pathway in neonatal hypoxic-ischaemic brain injury

Kye Hee Cho
Jee In Choi
MinYoung Kim
ResearchOpen Access10 Mar 2020
Scientific Reports

Volume: 10, P: 1-13
Development and application of rTMS device to murine model

Jin Seung Choung
Sohom Bhattacharjee
MinYoung Kim
ResearchOpen Access04 Apr 2023
Scientific Reports

Volume: 13, P: 1-13
Escape behaviors in prey and the evolution of pennaceous plumage in dinosaurs

Jinseok Park
Minyoung Son
Piotr G. Jablonski
ResearchOpen Access25 Jan 2024
Scientific Reports

Volume: 14, P: 1-20
Therapeutic efficacy of repetitive transcranial magnetic stimulation in an animal model of Alzheimer’s disease

Jin Seung Choung
Jong Moon Kim
MinYoung Kim
ResearchOpen Access11 Jan 2021
Scientific Reports

Volume: 11, P: 1-12
Pushed to extremes: distinct effects of high temperature versus pressure on the structure of STEP

A multi-perturbation crystallographic study on the atypical phosphatase STEP reveals that temperature and pressure are powerful macromolecular perturbations, with distinct effects on protein backbone, side-chain conformations, and ordered solvent.

Liliana Guerrero
Ali Ebrahim
Daniel A. Keedy
ResearchOpen Access12 Jan 2024
Communications Biology

Volume: 7, P: 1-13
Potential range shift of a long-distance migratory rice pest, Nilaparvata lugens, under climate change

Jinsol Hong
Minyoung Lee
Kijong Cho
ResearchOpen Access21 May 2024
Scientific Reports

Volume: 14, P: 1-14
Oncogenic KRAS promotes growth of lung cancer cells expressing SLC3A2-NRG1 fusion via ADAM17-mediated shedding of NRG1

Dong Hoon Shin
Sun Ha Kim
Ji-Youn Han
Research06 Nov 2021
Oncogene

Volume: 41, P: 280-292
MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells

Hyejeong Kim
Yeongrim Ko
Young-Guen Kwon
ResearchOpen Access13 Nov 2019
Experimental & Molecular Medicine

Volume: 51, P: 1-11
FYN promotes mesenchymal phenotypes of basal type breast cancer cells through STAT5/NOTCH2 signaling node

Ga-Hang Lee
Ki-Chun Yoo
Su-Jae Lee
Research19 Jan 2018
Oncogene

Volume: 37, P: 1857-1868
A new exceptionally well-preserved basal actinopterygian fish in the juvenile stage from the Upper Triassic Amisan Formation of South Korea

Su-Hwan Kim
Yuong-Nam Lee
Minyoung Son
ResearchOpen Access03 Jan 2024
Scientific Reports

Volume: 14, P: 1-14
The effects of the voglibose on non-alcoholic fatty liver disease in mice model

Jaehyun Bae
Ji Young Lee
Bong-Soo Cha
ResearchOpen Access10 Aug 2022
Scientific Reports

Volume: 12, P: 1-8
Combination of automated brain volumetry on MRI and quantitative tau deposition on THK-5351 PET to support diagnosis of Alzheimer’s disease

Minjae Kim
Sang Joon Kim
Jae Seung Kim
ResearchOpen Access14 May 2021
Scientific Reports

Volume: 11, P: 1-10
Preparing pathological data to develop an artificial intelligence model in the nonclinical study

Ji-Hee Hwang
Minyoung Lim
Jae-Woo Cho
ResearchOpen Access08 Mar 2023
Scientific Reports

Volume: 13, P: 1-11
Human umbilical cord-derived mesenchymal stem cells alleviate schizophrenia-relevant behaviors in amphetamine-sensitized mice by inhibiting neuroinflammation

Min-Jung You
Minji Bang
Min-Soo Kwon
ResearchOpen Access27 Apr 2020
Translational Psychiatry

Volume: 10, P: 1-15

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