Intravesical injection of botulinum toxin-A has been shown to provide effective treatment for patients with detrusor overactivity refractory to first-line treatment with anticholinergics. In this Review, the authors discuss the currently available data regarding repeated injections of botulinum toxin-A to patients with neurogenic and idiopathic detrusor overactivity, and consider the efficacy and clinical considerations of this treatment modality.
- Christopher Dowson
- Mohammad Shamim Khan
- Arun Sahai
