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The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

Analysis of soundscape data from 139 globally distributed sites reveals that sounds of biological origin exhibit predictable rhythms depending on location and season, whereas sounds of anthropogenic origin are less predictable. Comparisons between paired urban–rural sites show that urban green spaces are noisier and dominated by sounds of technological origin.

Bleaching threatens corals worldwide as the oceans warm from climate change. Here the authors provide insight into intergenerational acclimatization potential by identifying metabolomic signatures of coral resistance to bleaching at all stages of development, including in the new generation.

A microfluidic-based system enables fast screening of Mycobacterium tuberculosis infection through analysis of specific T-cell responses.

Autocatalysis is a process whereby a product accelerates its own formation. Here, the authors describe a system whereby two simple components combine irreversibly to give a more complex, amphiphilic product, leading to autocatalytically active micelles.

The use of antiferromagnetic materials in spintronic devices has been proposed as an attractive alternative to ferromagnets, but only a few suitable materials are known. Here, the authors synthesize a new antiferromagnet (AFM)—tetragonal epitaxial CuMnAs—and show that it is ideal for spintronic applications.

Precise surface modification of titanium dioxide is useful for numerous applications. Here, the authors report that high ion dose bombardment transforms the surface of titanium dioxide (110) into single-crystalline titanium oxide (001) thin film, unlike previous lower energy ion bombardment studies.

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Single quantum dot tracking is an established technique used in cultured neurons and organotypic brain slices. Here, the authors demonstrate in vivotargeting of dopamine receptors via ventricular injection of functionalized quantum dots and track single nanoparticle-receptors in acute rat brain slices.

A dataset of coding variation, derived from exome sequencing of nearly one million individuals from a range of ancestries, provides insight into rare variants and could accelerate the discovery of disease-associated genes and advance precision medicine efforts.

Hibernating ground squirrels have negligible hunger despite a months-long period of food deprivation and cold exposure. Here, authors show that prolonged anorexia is enabled by inhibition of the hypothalamic feeding center due to central hypothyroidism.

Interactions between European bird and plant species show that fruiting period has a major effect on seed dispersal by migrating birds, which will influence plant adaptations to climate change through latitudinal dispersal.

Plasma turbulence is the main driver to deteriorate the performance of fusion power plants. This work presents an unprecedented comparison of plasma turbulence between experiment and simulation, proving that the gyrokinetic model GENE reached a high level of maturity to predict core turbulence.

Ultra-high-energy gamma-ray emission from the microquasar V4641 Sagittarii is reported, suggesting that large-scale jets from microquasars could be more common than previously thought and also could be a notable source of galactic cosmic rays.

In fruit flies, three-dimensional organ arrangement is stereotypical, sexually dimorphic and actively maintained by muscle-vessel mechanochemical crosstalk.

AgRP neurons regulate feeding behavior by promoting signals of hunger. Here, the authors show that miR-33, represses the activity of AgRP neurons, and selective loss of miR-33 in AgRP neurons promotes obesity and metabolic dysfunction in mice.

The CMS Collaboration reports evidence for off-shell Higgs boson contributions in the production of Z boson pairs, and measures the width of the Higgs boson, which is inversely related to its lifetime.

The electrochemical transformation of CO₂ into liquid fuels is a major challenge. Now, Jaramillo, Hahn and co-workers present a Au/Cu catalyst highly active to C₂₊ alcohols at low overpotentials as a result of a tandem mechanism where CO₂ is reduced to CO on Au and further reduced to C₂₊ alcohols on nearby Cu.

Edge-localized plasma modes in a tokamak can damage its innermost wall. Simulations now show that fast ions can modify the spatio-temporal structure of these modes. These effects need to be considered in the optimization of control techniques.

The CMS Collaboration reports the study of three simultaneous hard interactions between quarks and gluons in proton–proton collisions. This manifests through the concurrent production of three J/ψ mesons, which consist of a charm-quark–antiquark pair.

To celebrate the first 10 years ofNature Reviews Neuroscience, we invited the authors of the most cited article of each year to look back on the state of their field at the time of publication and the impact their article has had, and to discuss the questions that might be answered in the next 10 years.

Durable agonism of NPR1 achieved with a novel investigational monoclonal antibody could mirror the positive hemodynamic changes in blood pressure and heart failure identified in humans with lifelong exposure to NPR1 coding variants.

Determining how to respond to others in distress is central to social cognition. In a new model, male rats approach stressed juveniles but avoid stressed adults; these behaviors require excitatory action of oxytocin within the insular cortex.

Some bacteria can take up DNA molecules from the environment. Here, Damke et al. identify a DNA-binding protein in Helicobacter pylori that is required for DNA import into the periplasm and that interacts with an inner-membrane channel that translocates the DNA into the cytoplasm.

Autocatalytic lipids and their assemblies may have had a special and underappreciated role in the origin of life. This Review discusses how simple lipids can collectively generate fascinating systems-level phenomena and enable functions beyond reproduction, such as selection and soft materials applications.

Widespread shallow-water hydrothermal venting in the North Atlantic, probably a source of methane, coincided with the onset of the Palaeocene–Eocene Thermal Maximum, according to borehole proxy records and seismic imaging.

The most up-to-date combination of results on the properties of the Higgs boson is reported, which indicate that its properties are consistent with the standard model predictions, within the precision achieved to date.

Interfacial magnetoelectric coupling could lead to a new generation of memory devices. Here, Bertacco and colleagues observe a large electric-field switchable magnetoelectric coupling effect in iron/barium titanate heterostructures, which is due to a thin oxidized iron layer.

Drug delivery implants suffer from diminished release profiles due to fibrous capsule formation over time. Here, the authors use soft robotic actuation to modulate the immune response of the host to maintain drug delivery over the longer-term and to perform controlled release in vivo.

An exome-wide association study of six smoking phenotypes in up to 749,459 individuals identifies associations of rare coding variants in CHRNB2 that may reduce the likelihood of smoking.

The authors find that glutamate release increases the diffusion of the astrocytic glutamate transporter GLT-1 in the plasma membrane. This activity-dependent increase in mobility facilitates glutamate clearance from the synaptic cleft, which influences the kinetics of excitatory post-synaptic events in rat hippocampal neurons.

An epicardial device that enables sustained and repeated administration of small molecules, macromolecules and cells directly to the epicardium provides therapeutic benefits in a rat model of myocardial infarction.

The suppression of edge-localized modes in tokamak plasmas is crucial to prevent them from damaging the walls of the chamber. Now experiments confirm the role that magnetic islands play in suppressing these detrimental modes.

CAG-repeat expansion in the housekeeping gene ATXN7 causes the neurodegenerative disorder SCA7. Now ATXN7 protein is found to promote transcription and expression of miR-124, which in turn mediates cross-talk between lnc-SCA7 and ATXN7 transcripts.

The composition of toxic protein aggregates associated with neurodegenerative diseases is difficult to determine. Now, a method has been developed that can capture amyloid-containing aggregates in human biofluids using a structure-specific chemical dimer. This method—known as amyloid precipitation—enables unbiased determination of the molecular composition and structural features of the in vivo aggregates.

This study shows that UTX (KDM6A) suppresses myeloid leukemogenesis through noncatalytic functions. UTX loss leads to alterations in H3K27ac, H3K4me1 and chromatin accessibility, and in gene-regulatory programs mediated by ETS and GATA transcription factors.