Nature Search

Bioengineered hybrid dual-targeting nanoparticles reprogram the tumour microenvironment for deep glioblastoma photodynamic therapy

The combination of photodynamic therapy and immunotherapy is emerging as a promising treatment for glioblastoma (GBM). Here this group encapsulates Fe3O4@BiFeO3 into bacterial outer membrane vesicles and M1 macrophage-derived exosomes hybrid membrane for synergistic photo-immunotherapy of GBM.

Rongrong Zhao
Ying Hou
Hao Xue
ResearchOpen Access18 Aug 2025
Nature Communications

Volume: 16, P: 1-22
Frequency-encoded eye tracking smart contact lens for human–machine interaction

Eye tracking techniques enable high-efficient, natural, and effortless human-machine interaction. Here, Zhu et al. proposed a contact lens to track eye movement for wireless eye-machine interaction

Hengtian Zhu
Huan Yang
Fei Xu
ResearchOpen Access27 Apr 2024
Nature Communications

Volume: 15, P: 1-13
1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

A resource of >1,500 bacterial reference genomes sheds light on the human gut microbiome.

Yuanqiang Zou
Wenbin Xue
Liang Xiao
ResearchOpen Access04 Feb 2019
Nature Biotechnology

Volume: 37, P: 179-185
Bilayer electrified-membrane with pair-atom tin catalysts for near-complete conversion of low concentration nitrate to dinitrogen

The selective and rapid reduction of nitrate at low concentration is technically challenging. Here, the authors report an electrified membrane loaded with Sn pair-atom catalysts that realizes near-complete removal of 10 mg-N/L nitrate and ~100% N₂ selectivity during electro-filtration.

Xuanhao Wu
Xiaoxiong Wang
Jae-Hong Kim
ResearchOpen Access28 Jan 2025
Nature Communications

Volume: 16, P: 1-12
Sequence-based drug design as a concept in computational drug design

Conventional structure-based drug design pipeline is a complex, human-engineered process with multiple independently optimized steps. Here, the authors report a sequence-to-drug concept that discovers drug-like small molecule modulators directly from protein sequences.

Lifan Chen
Zisheng Fan
Mingyue Zheng
ResearchOpen Access14 Jul 2023
Nature Communications

Volume: 14, P: 1-21
Clinical and genomic features of Chinese lung cancer patients with germline mutations

Germline variants that predispose to lung cancer have been mostly studied in Western populations, but data from Chinese patients is lacking. Here the authors analyze lung cancer germline variants in 1794 Chinese patients, finding exclusive variants or with different frequency compared to TCGA data.

Wenying Peng
Bin Li
Lin Wu
ResearchOpen Access10 Mar 2022
Nature Communications

Volume: 13, P: 1-12
Evolutionary origin of the chordate nervous system revealed by amphioxus developmental trajectories

Analysis of single-cell RNA-sequencing data from seven amphioxus embryo stages informs the evolution of chordate cell type evolution and reveals three developmental origins for the vertebrate nervous system.

Yichen Dai
Yanhong Zhong
Guang Li
Research18 Jul 2024
Nature Ecology & Evolution

Volume: 8, P: 1693-1710
Discovery and mechanism-guided engineering of BHET hydrolases for improved PET recycling and upcycling

The degradation of PET using PETase enzymes has great potential but can face problems with incomplete degradation. Here, the authors identified two BHETases from the environment and engineered them to improve their hydrolysis efficiency for applications in dual-enzyme PET recycling and tandem chemical-enzymatic PET upcycling systems.

Anni Li
Yijie Sheng
He Huang
ResearchOpen Access13 Jul 2023
Nature Communications

Volume: 14, P: 1-16
Efficient continuous SF₆/N₂ separation using low-cost and robust metal-organic frameworks composites

SF₆/N₂ separation is crucial for sustainable development. Here, the authors prepared low-cost and robust MOF composite pellets and established a vacuum temperature swing adsorption process with both high recovery and high purity of SF₆.

Jinjian Li
Yuting Chen
Qiwei Yang
ResearchOpen Access13 Jan 2025
Nature Communications

Volume: 16, P: 1-11
Ameba-inspired strategy enhances probiotic efficacy via prebound nutrient supply

Nutrient competition is a major obstacle to probiotic survival and success in treating inflammatory bowel disease. Here, the authors report on an ameba-inspired food-carrying strategy developed to provide a prebound food supply, free from competition, to improve probiotic survival increasing therapeutic potential.

Chao Pan
Xiuxian Jiang
Yong Gan
ResearchOpen Access20 Feb 2025
Nature Communications

Volume: 16, P: 1-17
Development of graphitic carbon nitride quantum dots-based oxygen self-sufficient platforms for enhanced corneal crosslinking

NCOMMS-23-46799C Keratoconus can be effectively stabilized by corneal crosslinking (CXL), but the depletion of stromal oxygen limits the efficiency of CXL photochemical reactions. Here the authors address this issue by developing biocompatible graphitic carbon nitride quantum dots- based oxygen self-sufficient platforms.

Mei Yang
Tingting Chen
Jinhai Huang
ResearchOpen Access29 Jun 2024
Nature Communications

Volume: 15, P: 1-19
Nitrogen-doped carbon-based phenolic resin loaded with Pd NPs for hydrodechlorination of 4-Chlorophenol

Zhengyu Pan
Xianlang Chen
Jianrong Chen
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Arctic Amplification of marine heatwaves under global warming

The authors show a marked intensification of marine heatwaves in the Arctic Ocean due to sea ice decline, which is expected to surpass the global mean intensification of marine heatwaves by over sevenfold in future warming climate.

Yan He
Qi Shu
Fangli Qiao
ResearchOpen Access26 Sept 2024
Nature Communications

Volume: 15, P: 1-9
Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants

Most recent SARS-CoV-2 variants showed exceptional immune evasion properties. Here, the authors identify a highly conserved epitope within the RBD targeted by a broad spectrum neutralizing antibody BA7535 that shows therapeutic antiviral potency in mouse studies.

Yanqun Wang
An Yan
Jincun Zhao
ResearchOpen Access29 Jan 2024
Nature Communications

Volume: 15, P: 1-15
Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L.

Sequencing of haploid sugarcane, Saccharum spontaneum, allows assembly of a prototypical version of the sugarcane chromosome set. This new reference genome will serve as a resource to accelerate sugarcane improvement.

Jisen Zhang
Xingtan Zhang
Ray Ming
ResearchOpen Access08 Oct 2018
Nature Genetics

Volume: 50, P: 1565-1573
Digital economy and carbon efficiency: the roles of population aging and human capital

Rongrong Li
Qiang Wang
Ting Yang
ResearchOpen Access09 May 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-16
Molecular landscape of ERBB2 alterations in 3000 advanced NSCLC patients

Lingzhi Hong
Sonia Patel
Xiuning Le
ResearchOpen Access01 Oct 2024
npj Precision Oncology

Volume: 8, P: 1-11
Doubling of annual forest carbon loss over the tropics during the early twenty-first century

Using different high-resolution satellite datasets, this study analyses gross forest carbon loss associated with forest removal over the tropics during the twenty-first century focusing on regional fluxes and trends, as well as drivers of loss, both aspects rarely studied in previous work.

Yu Feng
Zhenzhong Zeng
Chunmiao Zheng
ResearchOpen Access28 Feb 2022
Nature Sustainability

Volume: 5, P: 444-451
Safety and immunogenicity of Ad5-nCoV immunization after three-dose priming with inactivated SARS-CoV-2 vaccine in Chinese adults

Here the authors provide safety and immunogenicity data for an AdV5-based SARS-CoV-2 vaccine, administered intramuscularly as heterologous booster after three-doses of inactivated SARS-CoV-2 vaccine in Chinese adults.

Hangjie Zhang
Nani Xu
Huakun Lv
ResearchOpen Access08 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Manipulating spin polarization of titanium dioxide for efficient photocatalysis

Photocatalyst activity depends significantly on the material’s electronic structures. Here, authors manipulate the electron spin polarization of TiO₂ by tuning the concentration of Ti vacancies and show improved photocatalytic activities.

Lun Pan
Minhua Ai
Wenbo Mi
ResearchOpen Access21 Jan 2020
Nature Communications

Volume: 11, P: 1-9
Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO

The two-component regulatory system VraRS regulates transcription of penicillin-binding protein 2 in response to cell wall antimicrobials. Here, Lu et al. show that an enzyme from the wall teichoic acid biosynthetic pathway of MRSA can also modulate the expression of virulence factors such as Staphylococcal protein A via VraRS.

Yunfu Lu
Feifei Chen
Lefu Lan
ResearchOpen Access22 Mar 2023
Nature Communications

Volume: 14, P: 1-19
Tuning the light emission of a Si micropillar quantum dot light-emitting device array with the strain coupling effect

A strain coupling device of QLED array based on Si micropillars is designed in this work. The device has high reference value in the field of pressure sensing and Si-based photonic integration.

Yepei Mo
Xiaolong Feng
Caofeng Pan
ResearchOpen Access14 Oct 2022
NPG Asia Materials

Volume: 14, P: 1-9
Pt/Fe₂O₃ with Pt–Fe pair sites as a catalyst for oxygen reduction with ultralow Pt loading

Atomically dispersed platinum electrocatalysts for oxygen reduction promise minimized platinum usage, but catalytic activity and selectivity are often low due to unfavourable O₂ adsorption. To circumvent this issue, Gao and colleagues load platinum onto α-Fe₂O₃, making a highly active and stable catalyst with dispersed Pt–Fe pair sites.

Ruijie Gao
Jian Wang
Ji-Jun Zou
Research20 May 2021
Nature Energy

Volume: 6, P: 614-623
Self-powered Real-time Movement Monitoring Sensor Using Triboelectric Nanogenerator Technology

Liangmin Jin
Juan Tao
Caofeng Pan
ResearchOpen Access05 Sept 2017
Scientific Reports

Volume: 7, P: 1-6
Atomic Step Formation on Sapphire Surface in Ultra-precision Manufacturing

Rongrong Wang
Dan Guo
Guoshun Pan
ResearchOpen Access22 Jul 2016
Scientific Reports

Volume: 6, P: 1-9
Skin-inspired highly stretchable and conformable matrix networks for multifunctional sensing

Electronic skins have been developed to emulate human sensory systems, but simultaneous detection of multiple stimuli remains a big challenge due to coupling of electronic signals. Here, Hua et al. overcome this problem in a stretchable and conformable matrix network integrated with seven different modes.

Qilin Hua
Junlu Sun
Zhong Lin Wang
ResearchOpen Access16 Jan 2018
Nature Communications

Volume: 9, P: 1-11
Real-time pressure mapping smart insole system based on a controllable vertical pore dielectric layer

Juan Tao
Ming Dong
Caofeng Pan
ResearchOpen Access10 Aug 2020
Microsystems & Nanoengineering

Volume: 6, P: 1-10
CD8⁺ T effector and immune checkpoint signatures predict prognosis and responsiveness to immunotherapy in bladder cancer

Xingyu Chen
Runshi Xu
Ke Cao
Research22 Sept 2021
Oncogene

Volume: 40, P: 6223-6234
A global-scale framework for hydropower development incorporating strict environmental constraints

The development of hydropower offers a renewable energy source that can help reduce society’s dependence on fossil fuels. A global assessment of the unused profitable hydropower potential can be performed by incorporating strict constraints to identify hydropower station locations with reduced environmental and societal impacts.

Rongrong Xu
Zhenzhong Zeng
Eric. F. Wood
Research16 Jan 2023
Nature Water

Volume: 1, P: 113-122
Does larger scale enhance carbon efficiency? Assessing the impact of corporate size on manufacturing carbon emission efficiency

Qiang Wang
Tingting Sun
Rongrong Li
ResearchOpen Access02 Aug 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-15
Does renewable energy reduce energy intensity? A matter of income inequality

Rongrong Li
Zhuang Yang
Qiang Wang
ResearchOpen Access05 Feb 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-22
How aging impacts environmental sustainability—insights from the effects of social consumption and labor supply

Shuyu Li
Qiang Wang
Rongrong Li
ResearchOpen Access11 Mar 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-16
Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury

Chen Li
Zhourui Wu
Liming Cheng
ResearchOpen Access02 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-15
Ecological footprints, carbon emissions, and energy transitions: the impact of artificial intelligence (AI)

Qiang Wang
Yuanfan Li
Rongrong Li
ResearchOpen Access14 Aug 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-18
Nobiletin alleviates cisplatin-induced ototoxicity via activating autophagy and inhibiting NRF2/GPX4-mediated ferroptosis

Wenao Song
Li Zhang
Zhiming Lu
ResearchOpen Access03 Apr 2024
Scientific Reports

Volume: 14, P: 1-16
RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke

Rongrong Zhang
Yanping Wu
Xinyue Qin
ResearchOpen Access02 Feb 2018
Cell Death & Differentiation

Volume: 25, P: 1503-1516
LncRNA H19 overexpression induces bortezomib resistance in multiple myeloma by targeting MCL-1 via miR-29b-3p

Yafang Pan
Yu Zhang
Hongmei Chen
ResearchOpen Access06 Feb 2019
Cell Death & Disease

Volume: 10, P: 1-14
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia

Qindong Guo
Yang Fan
Gang Li
ResearchOpen Access21 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-14
Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway

Shulin Zhao
Boyan Li
Gang Li
Research17 Nov 2022
Oncogene

Volume: 42, P: 138-153
IL-17-triggered downregulation of miR-497 results in high HIF-1α expression and consequent IL-1β and IL-6 production by astrocytes in EAE mice

Kai Shan
Rongrong Pang
Wen Qiu
Research01 May 2017
Cellular & Molecular Immunology

Volume: 14, P: 909-923
Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression

Ming Li
Hao Xu
Gang Li
ResearchOpen Access09 Sept 2022
Oncogene

Volume: 41, P: 4618-4632
The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs

Yanhua Qi
Chuandi Jin
Gang Li
ResearchOpen Access02 May 2022
Cell Death & Disease

Volume: 13, P: 1-15
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction

Jianye Xu
Jian Zhang
Gang Li
ResearchOpen Access07 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-16
Molecular basis for the thermostability of Newcastle disease virus

Guoyuan Wen
Xiao Hu
Qingzhong Yu
ResearchOpen Access03 Mar 2016
Scientific Reports

Volume: 6, P: 1-9
Spinal cord injury: molecular mechanisms and therapeutic interventions

Xiao Hu
Wei Xu
Liming Cheng
ReviewsOpen Access26 Jun 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-28

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