Nature Search

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants

E Theodoratou
H Campbell
S M Farrington
ResearchOpen Access09 Nov 2010
British Journal of Cancer

Volume: 103, P: 1875-1884
Vanadium K-edge X-ray absorption spectrum of the VFe protein of the vanadium nitrogenase of Azotobacter chroococcum

Judith M. Arber
Barry R. Dobson
Barry E. Smith
Research22 Jan 1987
Nature

Volume: 325, P: 372-374
Publisher Correction: Indo-Pacific Walker circulation drove Pleistocene African aridification

H. J. L. van der Lubbe
I. R. Hall
J. C. A. Joordens
Amendments and Corrections23 Feb 2022
Nature

Volume: 603, P: E5-E6
Indo-Pacific Walker circulation drove Pleistocene African aridification

A record of flow-speed variations from an ocean core shows that a key component of Indian Ocean circulation rapidly accelerated 2.1 million years ago, coincident with intensification of Pacific Walker circulation.

H. J. L. van der Lubbe
I. R. Hall
J. C. A. Joordens
Research27 Oct 2021
Nature

Volume: 598, P: 618-623
Dynamic control of function by light-driven molecular motors

Light-driven artificial molecular switches and motors afford dynamic control of various molecular systems, ranging from catalytic to biological. This Perspective provides insight into the challenges that must be addressed to transition the field from the proof-of-concept stage to realization of its myriad applications.

Thomas van Leeuwen
Anouk S. Lubbe
Ben L. Feringa
Reviews29 Nov 2017
Nature Reviews Chemistry

Volume: 1, P: 1-7
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis

S F Zerp
A van Elsas
P I Schrier
ResearchOpen Access29 Jan 1999
British Journal of Cancer

Volume: 79, P: 921-926
Antarctic icebergs reorganize ocean circulation during Pleistocene glacials

Iceberg-trajectory models along with multi-proxy evidence from sediment cores from the Indian Ocean show that northward shifts in Antarctic iceberg melt redistributed freshwater in the Southern Ocean during the Pleistocene.

Aidan Starr
Ian R. Hall
Hucai Zhang
Research13 Jan 2021
Nature

Volume: 589, P: 236-241
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease

Multi-ancestry genome-wide association analyses identify new risk loci for Parkinson’s disease, and fine-mapping and co-localization analyses implicate candidate genes whose expression is associated with disease susceptibility.

Jonggeol Jeffrey Kim
Dan Vitale
Ignacio Mata
ResearchOpen Access28 Dec 2023
Nature Genetics

Volume: 56, P: 27-36
Effect of Acute Polycythemia on Newborn Renal Hemodynamics and Function

Uma R Kotagal
Leonard I Kleinman
Research01 Feb 1982
Pediatric Research

Volume: 16, P: 148-151
A detailed study of loss of heterozygosity on chromosome 17 in tumours from Li – Fraumeni patients carrying a mutation to the TP53 gene

J M Varley
M Thorncroft
J M Birch
Research20 Feb 1997
Oncogene

Volume: 14, P: 865-871
Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

There is currently no disease-modifying treatment for Parkinson’s disease, a common neurodegenerative disorder. Here, the authors use genetic variation associated with gene and protein expression to find putative drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome.

Catherine S. Storm
Demis A. Kia
Nicholas W. Wood
ResearchOpen Access20 Dec 2021
Nature Communications

Volume: 12, P: 1-14
Prognostic significance of allelic losses in primary melanoma

Eugene Healy
Christine Belgaid
Jonathan L Rees
Research15 May 1998
Oncogene

Volume: 16, P: 2213-2218
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

Ian Tomlinson
Emily Webb
Richard Houlston
Research08 Jul 2007
Nature Genetics

Volume: 39, P: 984-988
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

Peter Broderick
Luis Carvajal-Carmona
Richard S Houlston
Research14 Oct 2007
Nature Genetics

Volume: 39, P: 1315-1317
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

Emma Jaeger
Emily Webb
Ian Tomlinson
Research16 Dec 2007
Nature Genetics

Volume: 40, P: 26-28
Mutational spectrum of p53 gene in arsenic-related skin cancers from the blackfoot disease endemic area of Taiwan

C-H Hsu
S-A Yang
S-R Lin
ResearchOpen Access07 May 1999
British Journal of Cancer

Volume: 80, P: 1080-1086
Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage

Knowledge of genomic features specific to humans may be important for understanding disease. Here the authors demonstrate a potential role for these human-lineage-specific sequences in brain development and neurological disease.

Zhongbo Chen
David Zhang
Mina Ryten
ResearchOpen Access06 Apr 2021
Nature Communications

Volume: 12, P: 1-13
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

Regulation of gene expression and splicing are thought to be tissue-specific. Here, the authors obtain genomic and transcriptomic data from putamen and substantia nigra of 117 neurologically healthy human brains and find that splicing eQTLs are enriched for neuron-specific regulatory information.

Sebastian Guelfi
Karishma D’Sa
Mina Ryten
ResearchOpen Access25 Feb 2020
Nature Communications

Volume: 11, P: 1-16
Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores

Paula Saffie-Awad
Spencer M. Grant
Sara Bandres-Ciga
ResearchOpen Access03 Jul 2025
npj Parkinson's Disease

Volume: 11, P: 1-13
Recommendations for quality improvement in genetic testing for cystic fibrosis European Concerted Action on Cystic Fibrosis

E Dequeker
H Cuppens
J-J Cassiman
Research18 Oct 2000
European Journal of Human Genetics

Volume: 8, P: S2-S12
Intrarenal Blood Flow Distribution in Canine Puppies

Pedro A Jose
Alexander G Logan
Gilbert M Eisner
Research01 Aug 1971
Pediatric Research

Volume: 5, P: 335-344
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

Richard Houlston and colleagues identify four new susceptibility loci for colorectal cancer through a meta-analysis of genome-wide association data, followed by replication testing in a large collection of independent samples. The study brings to ten the number of confirmed loci harboring low-penetrance risk alleles for this common malignancy.

Richard S Houlston
Emily Webb
Malcolm G Dunlop
Research16 Nov 2008
Nature Genetics

Volume: 40, P: 1426-1435
Induction of telomerase activity by UV-irradiation in Chinese hamster cells

M Prakash Hande
A S Balajee
A T Natarajan
Research02 Oct 1997
Oncogene

Volume: 15, P: 1747-1752
A randomised, blinded, placebo-controlled, dose escalation study of the tolerability and efficacy of filgrastim for haemopoietic stem cell mobilisation in patients with severe active rheumatoid arthritis

JA Snowden
JC Biggs
PM Brooks
Research03 Dec 1998
Bone Marrow Transplantation

Volume: 22, P: 1035-1041
Key developments in renin–angiotensin–aldosterone system inhibition

The development of blockers of the renin–angiotensin–aldosterone system (RAAS) has led to the identification of new RAAS components that might contribute to the effectiveness and/or adverse effects of these drugs. Here, the authors describe the roles of the prorenin receptor, type 2 angiotensin II receptors, angiotensin 1–7 and aldosterone–angiotensin II interactions and discuss the potential of modulators of these components to enhance RAAS blockade with potentially beneficial effects in patients with cardiovascular and renal diseases.

Bruno Sevá Pessôa
Nils van der Lubbe
A. H. Jan Danser
Reviews20 Nov 2012
Nature Reviews Nephrology

Volume: 9, P: 26-36
The LRRK2 p.L1795F variant causes Parkinson’s disease in the European population

Lara M. Lange
Kristin Levine
Masharip Atadzhanov
ResearchOpen Access25 Mar 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Microstructural Studies of Carbon Black Filler in Standard Malaysia Rubber Grade L (SMRL)

Mohamad Deraman
Wan Manshol Wan Zin
W Wagner
Research01 Aug 1990
Polymer Journal

Volume: 22, P: 745-750
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

Ian PM Tomlinson
Emily Webb
Richard S Houlston
Research30 Mar 2008
Nature Genetics

Volume: 40, P: 623-630
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Richard Houlston and colleagues report a genome-wide association study for colorectal cancer. They report three loci newly associated with colorectal cancer, bringing the total number of common susceptibility loci to 20.

Malcolm G Dunlop
Sara E Dobbins
Richard S Houlston
Research27 May 2012
Nature Genetics

Volume: 44, P: 770-776
Age- and sex-standardised prevalence rates of fatigue in a large hospital-based sample of cancer patients

S Singer
S Kuhnt
A Brown
ResearchOpen Access12 Jul 2011
British Journal of Cancer

Volume: 105, P: 445-451
Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset

Kimberley J. Billingsley
Ines A. Barbosa
Sulev Koks
ResearchOpen Access22 May 2019
npj Parkinson's Disease

Volume: 5, P: 1-9
The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4

S J Lubbe
A M Pittman
R S Houlston
Research12 Dec 2011
Oncogene

Volume: 31, P: 3777-3784
A Combined Study of Headspace Volatiles using Human Sensory, Mass Spectrometry and Chemometrics

K. G. McAdam
J. Tetteh
C. Liu
ResearchOpen Access08 May 2020
Scientific Reports

Volume: 10, P: 1-17
Author Correction: Elucidating causative gene variants in hereditary Parkinson’s disease in the Global Parkinson’s Genetics Program (GP2)

Lara M. Lange
Micol Avenali
Masharip Atadzhanov
Amendments and CorrectionsOpen Access13 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-3
Telomerase activity in melanoma and non-melanoma skin cancer

C N Parris
S Jezzard
R F Newbold
ResearchOpen Access11 Dec 1998
British Journal of Cancer

Volume: 79, P: 47-53
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability

Regina H. Reynolds
Juan Botía
Mina Ryten
ResearchOpen Access17 Apr 2019
npj Parkinson's Disease

Volume: 5, P: 1-14
Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

E Webb
P Broderick
R S Houlston
ResearchOpen Access02 Dec 2008
British Journal of Cancer

Volume: 99, P: 2088-2093
Adjuvant trastuzumab emtansine in HER2-positive breast cancer patients with HER2-negative residual invasive disease in KATHERINE

Sibylle Loibl
Chiun-Sheng Huang
Norman Wolmark
ResearchOpen Access19 Sept 2022
npj Breast Cancer

Volume: 8, P: 1-6
Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: implications for antitelomerase therapy

Ana Preto
Sim K Singhrao
Christopher J Jones
Research05 Apr 2004
Oncogene

Volume: 23, P: 4136-4145
Longitudinal characterization of nasopharyngeal colonization with Streptococcus pneumoniae in a South African birth cohort post 13-valent pneumococcal conjugate vaccine implementation

Felix S. Dube
Jordache Ramjith
Mark P. Nicol
ResearchOpen Access21 Aug 2018
Scientific Reports

Volume: 8, P: 1-9
National study of colorectal cancer genetics

S Penegar
W Wood
R Houlston
ResearchOpen Access25 Sept 2007
British Journal of Cancer

Volume: 97, P: 1305-1309
HIV-exposure, early life feeding practices and delivery mode impacts on faecal bacterial profiles in a South African birth cohort

Shantelle Claassen-Weitz
Sugnet Gardner-Lubbe
Mamadou Kaba
ResearchOpen Access22 Mar 2018
Scientific Reports

Volume: 8, P: 1-15
Endoscopic transnasal removal of migrated dental implants

D. E. Lubbe
S. Aniruth
S. Liebenberg
Research26 Apr 2008
British Dental Journal

Volume: 204, P: 435-436
Deciphering the genetics of hereditary non-syndromic colorectal cancer

Eli Papaemmanuil
Luis Carvajal-Carmona
Ian Tomlinson
Research16 Jul 2008
European Journal of Human Genetics

Volume: 16, P: 1477-1486
Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

Clodagh Towns
Madeleine Richer
Masharip Atadzhanov
ResearchOpen Access12 Sept 2023
npj Parkinson's Disease

Volume: 9, P: 1-6
Strong glacial-interglacial variability in upper ocean hydrodynamics, biogeochemistry, and productivity in the southern Indian Ocean

Migration of the Subtropical Front during glacial and interglacial periods resulted in variability in the strength of the biological pump in the Southern Ocean sector of the Indian Ocean, according to sedimentary records from the Agulhas Plateau.

Deborah Tangunan
Melissa A. Berke
Hucai Zhang
ResearchOpen Access05 May 2021
Communications Earth & Environment

Volume: 2, P: 1-13
A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk

Emily Webb
Peter Broderick
Richard S Houlston
Research27 May 2009
European Journal of Human Genetics

Volume: 17, P: 1507-1514
Erratum: A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk

Emily Webb
Peter Broderick
Richard S Houlston
Amendments and Corrections22 Sept 2011
European Journal of Human Genetics

Volume: 19, P: 1110
The IMAGEN study: a decade of imaging genetics in adolescents

Lea Mascarell Maričić
Henrik Walter
Amir Tahmasebi
ReviewsOpen Access29 Jun 2020
Molecular Psychiatry

Volume: 25, P: 2648-2671

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