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Showing 1–50 of 462 results

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Poziotinib for EGFR exon 20-insertion NSCLC: Clinical efficacy of the phase 2 ZENITH trial and differential impact of EGFR exon 20 insertion location on sensitivity

The location of EGFR exon 20 loop insertions (EGFRex20ins) has been shown to alter sensitivity to lung cancer therapy. Here, the authors report the results of the ZENITH20 clinical trial investigating poziotinib (EGFR TKI) in lung cancer patients and, combining with a similar trial, investigate how structural differences due to location of EGGFRex20ins alters sensitivity to EGFR TKI.

Xiuning Le
Jacqulyne P. Robichaux
John V. Heymach
ResearchOpen Access24 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Potassium Ions and the Binding of Cardiac Glycosides to Mammalian Cells

P. F. BAKER
J. S. WILLIS
Research09 May 1970
Nature

Volume: 226, P: 521-523
Mechanism of high-mannose N-glycan breakdown and metabolism by Bifidobacterium longum

The human gut Bifidobacterium longum can use host N-glycans as carbon and energy sources via a specific and cooperative multienzymatic system.

Rosa L. Cordeiro
Camila R. Santos
Mario T. Murakami
Research28 Nov 2022
Nature Chemical Biology

Volume: 19, P: 218-229
Raman Spectrum of Alumina and the Luminescence and Absorption Spectra of Ruby

R. S. KRISHNAN
Research05 Jul 1947
Nature

Volume: 160, P: 26
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling

Santos et al found that the ubiquitin ligase adaptor Fbxo42 is a critical regulator of terminal Unfolded Protein Response signaling through its control of Ataxin-2 granules containing Xbp1 mRNA.

Cristiana C. Santos
Nadine Schweizer
Pedro M. Domingos
ResearchOpen Access13 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Academic barriers at high altitude

Peter D. Moore
Books & Arts22 Oct 1981
Nature

Volume: 293, P: 686
More to melanism than meets the eye

J.S. Jones
News & Views11 Nov 1982
Nature

Volume: 300, P: 109-110
A distinct giant coat protein complex II vesicle population in Arabidopsis thaliana

The coat protein complex II (COPII) is a type of specialized vesicle coat protein that mediates vesicle trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus. A population of giant COPII vesicles is identified and shown to be produced in response to the plant hormone abscisic acid (ABA) and abiotic stresses in Arabidopsis.

Baiying Li
Yonglun Zeng
Liwen Jiang
Research07 Oct 2021
Nature Plants

Volume: 7, P: 1335-1346
Inhibition of release of prostaglandins as an explanation of some of the actions of anti-inflammatory corticosteroids

G. P. Lewis
Priscilla J. Piper
Research27 Mar 1975
Nature

Volume: 254, P: 308-311
Correlation between CTG trinucleotide repeat length and frequency of severe congenital myotonic dystrophy

Catherine Tsilfidis
Alex E. MacKenzie
Robert G. Korneluk
Research01 Jun 1992
Nature Genetics

Volume: 1, P: 192-195
A monolithically integrated plasmonic infrared quantum dot camera

Infrared cameras are used for night vision and in medical diagnostics, but currently only present monochrome images. Krishnaet al. demonstrate a monolithically intergrated plasmonic infrared quantum dot camera as a step towards coloured infrared imaging.

Sang Jun Lee
Zahyun Ku
Sam Kyu Noh
Research19 Apr 2011
Nature Communications

Volume: 2, P: 1-6
An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice

Here the authors discover that furanodienone (FDN), a small molecule derived from ginger, exhibits PXR agonist activity selective for the intestine and show that when FDN is administered orally in pharmacological doses ameliorates induced colitis in male mice.

Xiaojuan Wang
Guohui Zhang
Jiabao Liu
ResearchOpen Access03 Feb 2025
Nature Communications

Volume: 16, P: 1-19
Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch

Fang and colleagues show that the metabolite succinate can inhibit succinylation, and consequently protection from ubiquitin-mediated degradation, of the transcription factor FOXP3, with consequences on T_reg cell-suppressive function and IBD pathology.

Hai Wang
Danqing Hu
Deyu Fang
Research02 Jun 2025
Nature Immunology

Volume: 26, P: 866-880
The Relationship of Adrenal Androgens to the Secretory Patterns for Cortisol, Prolactin, and Growth Hormone During Early Puberty

Garry L Warne
John N Carter
Jeremy S D Winter
Research01 Mar 1979
Pediatric Research

Volume: 13, P: 211-213
Photosynthesis in the Ear of Barley

A. FREY-WYSSLING
M. S. BUTTROSE
Research26 Dec 1959
Nature

Volume: 184, P: 2031-2032
A persistent radon anomaly signal preceding the destructive 7.7 M_w earthquake in Myanmar on March 28, 2025

B. K. Sahoo
B. K. Sapra
D. K. Aswal
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Genome-wide association and fine-mapping analyses in ancestrally diverse populations implicate candidate causal genes and mechanisms underlying type 2 diabetes. Trans-ancestry genetic risk scores enhance transferability across populations.

Anubha Mahajan
Cassandra N. Spracklen
Andrew P. Morris
Research12 May 2022
Nature Genetics

Volume: 54, P: 560-572
The gut metabolite indole-3 propionate promotes nerve regeneration and repair

Elisabeth Serger
Lucia Luengo-Gutierrez
Simone Di Giovanni
Research22 Jun 2022
Nature

Volume: 607, P: 585-592
Synthesis of portimines reveals the basis of their anti-cancer activity

A scalable total synthesis of portimines enables structural reassignment of portimine B and in-depth functional evaluation of portimine A, revealing that portimine A induces translation inhibition selectively in human cancer cells and is efficacious in vivo tumour-clearance models.

Junchen Tang
Weichao Li
Phil S. Baran
Research20 Sept 2023
Nature

Volume: 622, P: 507-513
Experimental Neurolathyrism in Monkeys

S. L. N. RAO
P. S. SARMA
S. SRIRAMACHARI
Research06 May 1967
Nature

Volume: 214, P: 610-611
ESHA-256_GBGO: a high-performance and optimized security framework for internet of medical thing

G. Murugan
M. Chinnadurai
ResearchOpen Access20 Mar 2025
Scientific Reports

Volume: 15, P: 1-22
Spinal cord injuries following electrical accidents

George Varghese
Mani M Mani
J B Redford
Research01 Jun 1986
Spinal Cord

Volume: 24, P: 159-166
Influence of carbon dioxide on level of ionised calcium in squid axons

P. F. BAKER
P. HONERJÄGER
Research11 May 1978
Nature

Volume: 273, P: 160-161
Qualitative surface roughness of lithium disilicate endo-crown for pulpotomized primary molars

Shaimaa M. Mahfouz Omer
Shaimaa S. El-Desouky
Reham M. Ali Abdel Latif
ResearchOpen Access11 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants

Current SARS-CoV-2 vaccines require several injections for optimal immune protection. Here, the authors report an intranasal live-attenuated vaccine that induces long-term immunity following a single dose and protects from SARS-CoV-2 wildtype and variants in non-human primate and small animal models.

Xiang Liu
Wern Hann Ng
Suresh Mahalingam
ResearchOpen Access26 Aug 2024
Nature Communications

Volume: 15, P: 1-19
Clinical validation of an AI-based pathology tool for scoring of metabolic dysfunction-associated steatohepatitis

In a prospective, regulatory-grade study of assistance to pathologists in MASH histology scoring, AIM-MASH-assisted reads by expert MASH pathologists were superior to unassisted reads and decreased inter-reader variability.

Hanna Pulaski
Stephen A. Harrison
Katy E. Wack
ResearchOpen Access04 Nov 2024
Nature Medicine

Volume: 31, P: 315-322
Mode of Action of Antibiotics in Stimulating Growth of Chicks

M. E. COATES
C. D. DICKINSON
W. F. J. CUTHBERTSON
Research25 Aug 1951
Nature

Volume: 168, P: 332
Effect of the myotonic dystrophy (DM) mutation on mRNA levels of the DM gene

Luc A. Sabouri
Mani S. Mahadevan
Robert G. Korneluk
Research01 Jul 1993
Nature Genetics

Volume: 4, P: 233-238
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection

By individually replacing 16 yeast genes encoding ABC transporters by GFP, mating and selecting for strains with accumulated mutations the authors create a Green Monster, a strain with deletions in all 16 genes.

Yo Suzuki
Robert P St Onge
Frederick P Roth
Research09 Jan 2011
Nature Methods

Volume: 8, P: 159-164
Age Determination of Seals

H. R. HEWER
Research10 Sept 1960
Nature

Volume: 187, P: 959-960
Synthesis and Characterization of Isomeric Biphenyl Containing Poly(aryl ether-bisketone)s II. Polymers Derived from 3,3′-(4-Fluorobenzoyl)biphenyl and Bisphenols

Rajarathnam S Mani
Barry R Weeks
Dillip K Mohanty
Research01 Apr 1994
Polymer Journal

Volume: 26, P: 403-415
Long-lasting memory of jasmonic acid-dependent immunity requires DNA demethylation and ARGONAUTE1

Jasmonic acid (JA) is involved in defence against herbivores. Once the plant is attacked, the memory of aggression can linger for weeks, including in newly formed leaves. The authors investigate what the induced changes in the transcriptome and methylome are, and uncouple short- and long-term effects of JA.

S. W. Wilkinson
A. Hannan Parker
J. Ton
Research05 Jan 2023
Nature Plants

Volume: 9, P: 81-95
Habits of Ants

W. WHITMAN BAILEY
Research10 Jul 1879
Nature

Volume: 20, P: 244
Age of the Saline Series in the Salt Range of the Punjab

B. SAHNI
B. S. TRIVEDI
Research20 Jan 1945
Nature

Volume: 155, P: 76-77
Analysis of human T-lymphotropic virus sequences in multiple sclerosis tissue

S. L. Hauser
C. Aubert
M. Brahic
Research10 Jul 1986
Nature

Volume: 322, P: 176-177
Human Breast Carcinoma examined by the Fluorescent Antibody Technique

G. A. STIRLING
E. H. DAOUD
L. E. HUGHES
Research21 Mar 1964
Nature

Volume: 201, P: 1235-1236
Federated learning enables big data for rare cancer boundary detection

Federated ML (FL) provides an alternative to train accurate and generalizable ML models, by only sharing numerical model updates. Here, the authors present the largest FL study to-date to generate an automatic tumor boundary detector for glioblastoma.

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access05 Dec 2022
Nature Communications

Volume: 13, P: 1-17
Sodium Dependence of the Rate of Onset of the Ouabain-induced Positive Inotropic Effect on Cardiac Muscle

MARIANNA S. TALBOT
Research07 Sept 1968
Nature

Volume: 219, P: 1053-1054
PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

CDK4/6 inhibitors have improved outcomes for patients with ER+ breast cancer, however, those with loss of RB1 function often fail to respond. Here, the authors identify a vulnerability of ER + /RB1- breast cancer on PRMT5 and via dual blockade of ER and PRMT5 therapeutically target this in patient-derived xenograft models.

Chang-Ching Lin
Tsung-Cheng Chang
Carlos L. Arteaga
ResearchOpen Access13 Mar 2024
Nature Communications

Volume: 15, P: 1-16
A proof-of-concept experimental-theoretical model to predict pesticide resistance evolution

Luna Qingyang Li
Liisa Parts
Alison Woollard
ResearchOpen Access23 Jul 2025
Heredity

P: 1-12
Gene delivery tool shows promise

K. S. Jayaraman
News06 Aug 2010
Nature India
Lightning Conductors

CHARLES S. TOMES
Research12 Jun 1879
Nature

Volume: 20, P: 145
Allergenic and Agricultural Implications of Airborne Ascospore Concentrations from a Fungus, Didymella exitialis

A. W. FRANKLAND
P. H. GREGORY
Research01 Oct 1973
Nature

Volume: 245, P: 336-337
Clinical and radiographic evaluation of premixed bioceramic putty as an apical plug in nonvital immature anterior permanent teeth

Mohamed S. Ghaly
Nura I. Abozena
Shaimaa S. EL-Desouky
ResearchOpen Access21 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Calcium-dependent release of somatostatin and neurotensin from rat brain in vitro

L. L. IVERSEN
S. D. IVERSEN
W. VALE
Research11 May 1978
Nature

Volume: 273, P: 161-163
Odor mixtures of opposing valence unveil inter-glomerular crosstalk in the Drosophila antennal lobe

Fruit flies need to appropriately respond to mixtures of attractive and repellent odors in their natural environment. Here, the authors propose that lateral inhibition between glomeruli activated by attractants or repulsive odors mediates the appropriate response.

Ahmed A. M. Mohamed
Tom Retzke
Silke Sachse
ResearchOpen Access13 Mar 2019
Nature Communications

Volume: 10, P: 1-17
Multimodal machine learning for risk-stratified bundled payments in spinal surgery

Kyle A. Mani
Samuel N. Goldman
Ananth S. Eleswarapu
ResearchOpen Access10 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-11
CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation

Exome sequencing identifies loss-of-function CELA2A mutations in families with early-onset atherosclerosis and metabolic syndrome. Functional studies show that CELA2A is a circulating enzyme that reduces platelet activation, triggers insulin secretion and degradation, and increases insulin sensitivity.

Fatemehsadat Esteghamat
James S. Broughton
Arya Mani
Research29 Jul 2019
Nature Genetics

Volume: 51, P: 1233-1243
The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma

Savita Bhalla
Sriram Balasubramanian
Andrew Evens
ResearchOpen Access12 Jul 2008
Nature Precedings

P: 1
Effect of UV Irradiation on The Structure of Heterophasic Ethylene-Propylene Copolymers

R Mani
R P Singh
J Lacoste
Research01 Oct 1994
Polymer Journal

Volume: 26, P: 1132-1141

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