Nature Search

Induction of Aseptic Sporangial Formation in Phytophthora cinnamomi By Metabolic Diffusates of Soil Micro-Organisms

DONALD H. MARX
FRANK A. HAASIS
Research01 May 1965
Nature

Volume: 206, P: 673-674
DARPin-induced reactivation of p53 in HPV-positive cells

The binding of a DARPin to p53 displaces the human papillomavirus (HPV) E6 protein and stabilizes p53 in HPV-infected cells. This interaction reactivates a p53-dependent transcriptional program, suggesting a potential new therapeutic strategy for treating HPV-induced cancers.

Philipp Münick
Alexander Strubel
Volker Dötsch
Research09 Jan 2025
Nature Structural & Molecular Biology

Volume: 32, P: 790-801
Effect of Sulphydryl Reactants on Liver Ribonuclease

JAY S. ROTH
Research17 Jan 1953
Nature

Volume: 171, P: 127-128
Comparison of major, minor and junctional circumsporozoite protein epitopes for malaria vaccine design

Emma Ryan
Dallas Brown
Sheetij Dutta
ResearchOpen Access03 Oct 2025
npj Vaccines

Volume: 10, P: 1-13
Memory trace interference impairs recall in a mouse model of Alzheimer’s disease

Mice with AD-like pathology and memory impairments surprisingly have memory engrams in their hippocampus. However, interference with novelty-like cells prevents proper recall, erroneously letting mice perceive a previously learned context as novel.

Stefanie Poll
Manuel Mittag
Martin Fuhrmann
Research08 Jun 2020
Nature Neuroscience

Volume: 23, P: 952-958
Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity

Commensal bacteria such as Lactobacillus rhamnosus can inhibit the pathogenicity of the fungus Candida albicans. Here, Alonso-Roman et al. investigate the interplay between C. albicans, L. rhamnosus and intestinal epithelial cells, showing that changes in the metabolic environment, induced by the bacteria, trigger adaptations in C. albicans that reduce fungal pathogenicity.

Raquel Alonso-Roman
Antonia Last
Mark S. Gresnigt
ResearchOpen Access09 Jun 2022
Nature Communications

Volume: 13, P: 1-15
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations

A large-scale CRISPR-mediated deep mutational scanning approach is used to interrogate the function of mutations in the endogenous locus of TP53 mapping to the DNA-binding domain.

Julianne S. Funk
Maria Klimovich
Thorsten Stiewe
ResearchOpen Access07 Jan 2025
Nature Genetics

Volume: 57, P: 140-153
Behaviour of Mammalian Hæmoglobin after Freezing and Thawing

S. SQUIRES
J. A. McFADZEAN
Research24 Aug 1963
Nature

Volume: 199, P: 783-784
DNA microbeads for spatio-temporally controlled morphogen release within organoids

Creating precise morphogen gradients for tissue engineering is challenging. Here the authors present mechanically tunable DNA hydrogel-based microbeads for light-controlled morphogen release in retinal organoids for better tissue mimicry.

Cassian Afting
Tobias Walther
Kerstin Göpfrich
ResearchOpen Access09 Sept 2024
Nature Nanotechnology

Volume: 19, P: 1849-1857
A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation

Actin is crucial for nervous system function yet the role of microexons in its modulation is unclear. Here, the authors show that a microexon in DAAM1 has a role in actin dynamics, neuronal function and memory formation in mice.

Patryk Poliński
Marta Miret Cuesta
Manuel Irimia
ResearchOpen Access06 May 2025
Nature Communications

Volume: 16, P: 1-21
Blobby is a synaptic active zone assembly protein required for memory in Drosophila

The active zone is a brain signaling hub critical for synaptic information transfer and the encoding of behaviors. The authors identify Blobby as an assembly factor required for proper active zone nanoscale protein architecture and memory formation.

J. Lützkendorf
T. Matkovic-Rachid
S. J. Sigrist
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Regulation of PV interneuron plasticity by neuropeptide-encoding genes

Increasing the activity of individual parvalbumin-expressing interneurons in the mouse brain modulates the number and strength of inhibitory parvalbumin synapses received by these cells through changes in the expression of the neuropeptide-encoding genes Vgf and Scg2.

Martijn Selten
Clémence Bernard
Oscar Marín
ResearchOpen Access30 Apr 2025
Nature

Volume: 643, P: 173-181
Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population

Adipose tissue is composed of a variety of cell types, including adipocyte precursor populations, that contribute to adipose tissue function upon differentiation. Here, using scRNA-sequencing of adolescent and adult mouse subcutaneous adipose tissue, the authors identify an Asc-1 positive preadipocyte population that is enriched in adolescent subcutaneous fat and demonstrate that loss of Asc-1 triggers spontaneous beige adipocyte differentiation.

Lisa Suwandhi
Irem Altun
Siegfried Ussar
ResearchOpen Access11 Mar 2021
Nature Communications

Volume: 12, P: 1-12
Haploid facultative parthenogenesis in sunflower sexual reproduction

Spontaneous parthenogenesis in sunflower has been used to develop a scalable doubled haploid breeding system.

Jian Lv
Dawei Liang
Timothy Kelliher
Research02 Apr 2025
Nature

Volume: 641, P: 732-739
Oxidation of retromer complex controls mitochondrial translation

Systematic base-editing and computational screens identify specific cysteine residues on VPS35 in the retromer complex as key sensors that decrease mitochondrial translation in response to reactive oxygen species signals.

Junbing Zhang
Md Yousuf Ali
Liron Bar-Peled
Research26 Mar 2025
Nature

Volume: 641, P: 1048-1058
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Antimicrobial peptide LL37 can bind nucleic acids and potentiate their sensing by endosomal TLRs. Here the authors show that LL37 binds to RNA from neutrophil extracellular traps (NETs), which amplifies inflammation and production of more LL37 and NETs via TLR8/13, suggesting that LL37 contribution to psoriasis may be fueled by NET-associated RNA.

Franziska Herster
Zsofia Bittner
Alexander N. R. Weber
ResearchOpen Access08 Jan 2020
Nature Communications

Volume: 11, P: 1-13
Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation

The role of cortical PV neurons in the regulation of sleep architecture and homeostatic sleep rebound is not fully understood. Here, the authors show that CaMKII-mediated control of cortical parvalbumin-neuron activity regulates the homeostatic sleep rebound in mice.

Kazuhiro Kon
Koji L. Ode
Hiroki R. Ueda
ResearchOpen Access18 Jul 2024
Nature Communications

Volume: 15, P: 1-19
Insulin-like growth factor II receptor as a multifunctional binding protein

David O. Morgan
Jeffrey C. Edman
William J. Rutter
Research24 Sept 1987
Nature

Volume: 329, P: 301-307
Photoactivation of silicon rhodamines via a light-induced protonation

Activatable fluorophores are of interest for a wide range of applications but the need for caging groups complicates their development and application. Here, the authors report on a photoactivatable silicon rhodamine derivative and its application in live cell imaging and single-particle tracking.

Michelle S. Frei
Philipp Hoess
Kai Johnsson
ResearchOpen Access08 Oct 2019
Nature Communications

Volume: 10, P: 1-10
Reward signaling in a recurrent circuit of dopaminergic neurons and peptidergic Kenyon cells

Olfactory information from Kenyon cells in the mushroom body and reward information from pPAM dopaminergic neurons is required for appetitive olfactory learning and memory. Here, the authors report evidence for a feedback circuit mechanism between Kenyon cells and pPAM neurons for reward memory that involves short neuropeptide F.

Radostina Lyutova
Mareike Selcho
Dennis Pauls
ResearchOpen Access15 Jul 2019
Nature Communications

Volume: 10, P: 1-14
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ

Kiourtis et al. show that liver senescence triggers senescence and dysfunction in other organs through TGFβ secretion from the liver.

Christos Kiourtis
Maria Terradas-Terradas
Thomas G. Bird
ResearchOpen Access13 Nov 2024
Nature Cell Biology

Volume: 26, P: 2075-2083
The molecular dissection of TRIM25’s RNA-binding mechanism provides key insights into its antiviral activity

The RNA-binding ubiquitin E3 ligase TRIM25 plays a critical role in antiviral immunity. Here the authors identify key RNA-binding residues of TRIM25, link RNA binding to antiviral activity, reveal RNA structural and sequence preferences, and investigate binding to the viral genome.

Lucía Álvarez
Kevin Haubrich
Janosch Hennig
ResearchOpen Access01 Oct 2024
Nature Communications

Volume: 15, P: 1-15
Photoblueing of organic dyes can cause artifacts in super-resolution microscopy

Commonly used organic dyes can photoconvert to blue-shifted fluorescent species, especially under intense illumination. The mechanism of this process and how to avoid unwanted artifacts in super-resolution microscopy are explored here.

Dominic A. Helmerich
Gerti Beliu
Markus Sauer
Research25 Feb 2021
Nature Methods

Volume: 18, P: 253-257
Insulin-receptor antibodies mimic a late insulin effect

E. VAN OBBERGHEN
P. M. SPOONER
C. GRUNFELD
Research01 Aug 1979
Nature

Volume: 280, P: 500-502
Thermal history of the H-group of chondritic meteorites

R. Hutchison
A. W. R. Bevan
J. R. Ashworth
Research30 Oct 1980
Nature

Volume: 287, P: 787-790
Potential for variability through multiple gene products of bacteriophage ΦX174

Thomas J. Pollock
Irwin Tessman
Ethel S. Tessman
Research01 Jul 1978
Nature

Volume: 274, P: 34-37
Long-range transport of tropospheric ozone

Öystein Hov
Eigil Hesstvedt
Ivar S. A. Isaksen
Research01 Jun 1978
Nature

Volume: 273, P: 341-344
Intracoronary gene transfer of fibroblast growth factor–5 increases blood flow and contractile function in an ischemic region of the heart

Frank J. Giordano
Peipei Ping
H. Kirk Hammond
Research01 May 1996
Nature Medicine

Volume: 2, P: 534-539
Marine and terrestrial contributions to atmospheric deposition fluxes of methylated arsenic species

Analyses of atmospheric samples at a high-altitude site show that methylated forms of arsenic, emitted via biological processes, represent an important share of arsenic deposition. These forms are transported from both marine and terrestrial systems.

Esther S. Breuninger
Julie Tolu
Lenny H. E. Winkel
ResearchOpen Access07 Nov 2024
Nature Communications

Volume: 15, P: 1-13
KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage

KDM4C regulates cathepsin L-mediated histone H3 N-terminal tail clipping through grainyhead-like 2 (GRHL2) methylation in breast cancer. This link between the cellular redox state and chromatin remodeling might represent a therapeutic target in KDM4C-amplified tumors.

Zheqi Li
Guillermo Peluffo
Kornelia Polyak
ResearchOpen Access02 Jun 2025
Nature Genetics

Volume: 57, P: 1463-1477
Magnetic spin imaging under ambient conditions with sub-cellular resolution

Detecting the magnetic spins of a small number of atoms is important for applications such as magnetic resonance imaging. Here, Steinert et al.demonstrate that nitrogen-vacancy defect centres in diamond allow spin detection at room temperature at length scales smaller than human cells.

S. Steinert
F. Ziem
J. Wrachtrup
Research19 Mar 2013
Nature Communications

Volume: 4, P: 1-6
Inhibition of high-affinity choline transport in peripheral cholinergic endings by presynaptic snake venom neurotoxins

MIKE J. DOWDALL
JAN P. FOHLMAN
DAVID EAKER
Research20 Oct 1977
Nature

Volume: 269, P: 700-702
Interaction of multiplication-stimulating activity with chick embryo fibroblasts demonstrates a growth receptor

MATTHEW M. RECHLER
JUDY M. PODSKALNY
S. PETER NISSLEY
Research15 Jan 1976
Nature

Volume: 259, P: 134-136
Membrane leakiness after viral infection and a new approach to the development of antiviral agents

Luis Carrasco
Research20 Apr 1978
Nature

Volume: 272, P: 694-699
Longitudinal field controls vector vortex beams in anisotropic epsilon-near-zero metamaterials

In this work, V. Aita et al. investigate the interaction of vector vortex beams with anisotropic metamaterials, showing how, depending on the state of polarization, their plasmonic resonances can be excited and exploited to modify the beam structure.

Vittorio Aita
Diane J. Roth
Anatoly V. Zayats
ResearchOpen Access23 Apr 2025
Nature Communications

Volume: 16, P: 1-11
[Letters to Editor]

ANOTHER F. Z. S.
Research17 Aug 1876
Nature

Volume: 14, P: 330-331
Where do general anaesthetics act?

N. P. Franks
W. R. Lieb
Research27 Jul 1978
Nature

Volume: 274, P: 339-342
Ammonia Toxicity and pH

KENNETH S. WARREN
Research07 Jul 1962
Nature

Volume: 195, P: 47-49
The parent structure of the layered high-temperature superconductors

T. Siegrist
S. M. Zahurak
R. S. Roth
Research21 Jul 1988
Nature

Volume: 334, P: 231-232
Brain motor and fear circuits regulate leukocytes during acute stress

Distinct brain regions differentially and rapidly tailor the leukocyte landscape during psychological stress, calibrating the ability of the immune system to respond to physical threats.

Wolfram C. Poller
Jeffrey Downey
Filip K. Swirski
Research30 May 2022
Nature

Volume: 607, P: 578-584
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB

Cun-Yu Wang
James C. Cusack Jr.
Albert S. Baldwin Jr.
Research01 Apr 1999
Nature Medicine

Volume: 5, P: 412-417
Male pygmy hippopotamus influence offspring sex ratio

Some animal populations are able to shift their birth sex ratio from the expected unity. This study shows, using fluorescencein situhybridization, that in a captive population of pygmy hippopotamus the males appear to be able to adjust the ratio of X- and Y-chromosome-bearing spermatozoa in their ejaculates.

Joseph Saragusty
Robert Hermes
Thomas B. Hildebrandt
ResearchOpen Access28 Feb 2012
Nature Communications

Volume: 3, P: 1-5
Heritable microbiome variation is correlated with source environment in locally adapted maize varieties

He et al. found that locally adapted maize varieties exert patterns of genetic control on their root and rhizosphere microbiomes that follow variation in their home environments, consistent with a role in tolerance to prevailing stress.

Xiaoming He
Danning Wang
Peng Yu
Research21 Mar 2024
Nature Plants

Volume: 10, P: 598-617
NK cell-derived IFNγ mobilizes free fatty acids from adipose tissue to promote early B cell activation during viral infection

Krapić, Kavazović and colleagues dissect the mechanism by which natural killer cells drive adipose tissue remodelling during viral infection, thus fuelling antiviral immune responses.

Mia Krapić
Inga Kavazović
Felix M. Wensveen
Research11 Apr 2025
Nature Metabolism

Volume: 7, P: 985-1003
A molecularly integrated amygdalo-fronto-striatal network coordinates flexible learning and memory

To behave flexibly, animals must form new memories and retrieve them later. Li et al. reveal an integrated (molecular-, structural- and circuit-based) system by which the ventral orbitofrontal cortex forms memory for adaptive actions and choice.

Dan C. Li
Niharika M. Dighe
Shannon L. Gourley
Research30 Aug 2022
Nature Neuroscience

Volume: 25, P: 1213-1224
Lower Dentition of Kenyapithecus africanus

L. S. B. LEAKEY
Research02 Mar 1968
Nature

Volume: 217, P: 827-830
Pharmacodynamics of Akt drugs revealed by a kinase-modulated bioluminescent indicator

Measuring pharmacodynamics (PD) is vital for drug development but traditional PD studies are labor and resource intensive. Wu et al. introduce a kinase-modulated bioluminescent indicator for noninvasive visualization of Akt-related drug PD in living animals.

Yan Wu
Chenzhou Hao
Michael Z. Lin
Research11 Feb 2025
Nature Chemical Biology

Volume: 21, P: 1194-1204
A Possible Function of Intracellular Ribonucleases

JAY S. ROTH
Research17 Jul 1954
Nature

Volume: 174, P: 129
Synthetic syntrophy for adenine nucleotide cross-feeding between metabolically active nanoreactors

Here the authors present a syntrophic vesicle system for selective transport of adenine nucleotides between ATP-producing and ATP-consuming nanoreactors. The platform can sustain synthetic cells, bionanoreactors and life-like entities with ATP.

Laura Heinen
Marco van den Noort
Bert Poolman
ResearchOpen Access21 Oct 2024
Nature Nanotechnology

Volume: 20, P: 112-120
Biodiversity, environmental drivers, and sustainability of the global deep-sea sponge microbiome

This study presents a large-scale analysis of microbial diversity in deep-sea sponges. They show that sponge microbial abundance status, geographic distance, sponge phylogeny and the physical-biogeochemical environment drive microbiome composition, in descending order of relevance. The uniqueness of each deep-sea sponge ground stresses the need for their strategic preservation.

Kathrin Busch
Beate M. Slaby
Ute Hentschel
ResearchOpen Access02 Sept 2022
Nature Communications

Volume: 13, P: 1-16

Search

Filter By:

Search

Quick links