Leukocytapheresis is a controversial nonpharmacologic treatment for IBD, in which white blood cells—the effector cells of the inflammatory process—are mechanically removed from the circulation. The authors of this Review discuss the rationale behind using leukocytapheresis, how it works in practice, its efficacy in patients with IBD and its current standing within guidelines for the treatment of IBD.
- Fridrik Thor Sigurbjörnsson
- Ingvar Bjarnason
