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A distinctive population with high hunter-gatherer ancestry persisted 3,000 years later than in most European regions, contributing to later Lower Rhine–Meuse Bell Beaker users.

Tree cover gains in the moist tropics (1982–2015) were 56% naturally regenerated forests and 27% managed tree systems, with forest type influencing carbon recovery. Effective forest restoration requires robust tracking of forest types established by restoration efforts.

A soft robotic probe enables continuous in utero monitoring of fetal physiological parameters, including heart rate, blood oxygen saturation, temperature and electrocardiogram data, during open or fetoscopic surgery to provide real-time information on fetal condition and distress.

Climate change can alter when and how animals grow, breed, and migrate, but it is unclear whether this allows populations to persist. This global study shows that shifts in seasonal timing are key to helping vertebrate species maintain population growth under global warming.

GRX-810, an oxide dispersion strengthened alloy, shows excellent structural performance above 1100°C and stability up to 1300 °C. Grain-size effects, additive manufacturing–induced anisotropy, and fine trigonal Y₂O₃ particles enhance creep resistance.

Following its internalisation, active endosomal GLP-1R engages with VAPB and SPHKAP at ER membrane contact sites to assemble a local cAMP/PKA condensate for the control of MICOS complex phosphorylation, mitochondrial remodelling and β-cell function.

Yamazoe et al. show that B cell-derived autoantibodies contribute to the development of atrial fibrillation, suggesting that targeting the humoral immune response may represent a viable therapeutic approach.

Living microbialites achieve high rates of carbon uptake and precipitation by bolstering photosynthesis with light-independent uptake mechanisms to provide an effective biological system to capture CO2 in the geologically stable carbonate, calcite.

Researchers at the Leibniz-Institute IHP demonstrate a silicon photonic platform that monolithically integrates ultra-fast >110 GHz germanium-silicon electro-absorption modulators and >200 GHz fin photodiodes, advancing next-gen optical communication technology.

Computational epitope heterogeneity analysis from simple dilution-series experiments can improve immunostaining in many laboratories. The analysis enables a computational single-color channel multiplexing based on binding properties.

Experimental evidence of coherent charge transport in the normal state of the kagome metal CsV₃Sb₅ is presented, revealing the nature of correlated order in kagome metals and new directions for exploring quantum coherence in correlated electron systems.

Khetarpal et al. show that the metabolic regulator PGC-1α is essential in heart muscle cells for exercise-driven cardiac growth, and that suppression of the stress-induced myokine GDF15 is required to enable cardiomyocyte adaptations to training.

Knowledge of payoffs has been assumed to be weakly beneficial for the emergence of cooperation between humans. Here the authors provide evidence to the contrary, showing that during interactions in a competitive environment access to information about payoffs leads to less cooperative behaviour.

Haptotaxis was traditionally seen as migration up protein gradients. It is now shown that cells can also oscillate or migrate down the gradient.

Detecting and counting individual microwave photons is important for processing quantum information, but it is made challenging by an absence of detectors that are sensitive enough to radiation at this wavelength. Correlations between microwave photons have now been measured using a series of amplifiers and digital analysis.

During starvation, muscle strength and endurance, are still critical for survival. Seven days of complete fasting did not reduce maximal strength in leg muscles, but maximal endurance capacity was decreased because carbohydrate oxidation was restrained.

The relative displacement of conducting molecules influences their electronic coupling and therefore the charge-transport properties of organic thin films. Electron diffraction patterns now reveal the dominant lattice vibrational modes in organic semiconductors with subnanometre precision and help predict the electronic behaviour of these materials.

Single-cell analysis of patient brains and cortical organoids links disrupted developmental metabolic reprogramming to postnatal synaptic dysfunction in dup15q syndrome, revealing shared neuronal changes with idiopathic autism.

Corporate procurement initiatives, such as RE100, can increase their impact on the energy transition by formulating ambitious interim targets and sourcing requirements, and by orchestrating corporate interests in countries with less ambitious renewable energy targets.

Fair finance in the energy sector is modelled in five climate–energy–economy models. The results show that convergence costs of capital could improve energy availability, affordability and sustainability in developing countries, thereby increasing the international equity of the energy transition.

This study employs a citizen science approach to identify and classify over 230,000 light sources in German city centers, suburbs and villages. The results underscore the pivotal role of citizen science in expanding knowledge of artificial light emissions and bolstering policymaking efforts to mitigate urban light pollution.

Time-resolved serial crystallography at XFELs reveals ultrafast photochemical reactions, but high laser densities can cause photodamage to biological samples. Here, the authors study the early K-intermediate in bacteriorhodopsin at high power, showing overall conformation remains robust over a wide range.

Psoriasis is a partially heritable skin disorder, the genetic basis of which is not fully understood. Here, the authors use genome-wide association meta-analysis to discover psoriasis susceptibility loci and genes, which encode existing and potential new drug targets.

The Broca area is located in the human prefrontal cortex and is involved in voluntary speech. Hage and Nieder now show that a monkey homologue of Broca’s area is similarly responsible for monkey volitional vocalizations.

Activation of caged fluorophores has mostly relied on the absorption of either a single ultraviolet photon or two NIR photons. Here, the authors show that two green photons (515 nm) can substitute for a single photon ( ~ 260 nm) to activate rhodamine-based dyes, thus enabling STED imaging in thick samples.

This Review establishes a roadmap to improve the sustainability of functional ceramics through a holistic approach that combines low-energy and low-CO₂ production methods, recycling strategies and supportive policy frameworks.

IFITM proteins can inhibit several viruses, but effects on SARS-CoV-2 infection are not well understood. Here, the authors show that endogenous IFITMs support SARS-CoV-2 infection in different in vitro models by binding spike and enhancing virus entry.

Arctic warming thaws permafrost, leading to enhanced soil mercury transport to the Arctic Ocean. Mercury isotope signatures in arctic rivers, ocean and atmosphere suggest that permafrost mercury is buried in marine sediment and not emitted to the global atmosphere

The observation of phase modes of charge density wave has been a long-standing challenge. Such low-energy phase excitations have now been seen in a transition metal dichalcogenide.

The authors present a super-bound state acoustic harvester that outperforms state-of-the-art acoustic energy harvesting systems.

Arachnoid cuff exit points create openings in the arachnoid barrier enabling the drainage of cerebrospinal fluid and exchange of molecules and cells between the dura and the subarachnoid space, therefore physically connecting the brain and the dura.

Designing optimal antibody-drug conjugates (ADCs) involves screening many complex parameters. Here, the authors present a payload-coupled chain-exchange technology for efficient ADC matrix production, demonstrating its power in designing ADCs targeting HER2.

There is a need for dataset-dependent MS² acquisition in trapped ion mobility spectrometry imaging. Here the authors report spatial ion mobility-scheduled exhaustive fragmentation (SIMSEF) which enables on-tissue metabolite and lipid annotation in mass spectrometry bioimaging studies, and use this to visualise the chemical space in rat brains.

By obtaining structural snapshots of the catalytic cycle of NADH:quinone oxidoreductase from Vibrio cholerae, the authors uncover its mechanism. They show how electrons are shuttled and determine the importance of the [2Fe-2S] cluster in the movement of the electron transfer switch.

Mice with AD-like pathology and memory impairments surprisingly have memory engrams in their hippocampus. However, interference with novelty-like cells prevents proper recall, erroneously letting mice perceive a previously learned context as novel.

Surfaces with adsorbed and arrested colloids are of interest for the engineering of advanced mesostructured materials. Here the authors demonstrate a method for producing particle-stabilised droplets with controlled surface coverage and composition.

This paper analyzes energy financing patterns of public export credit agencies (ECAs). It demonstrates that mainly European ECAs shifted away from fossil fuels, a transition accompanied by shifting support towards high-income countries.

Solar-powered standalone systems drastically lower the cost of electrifying sub-Saharan Africa. Household electrification can be provided at 7c USD per person per day on average. To reflect inter- and intra-country variance, policymakers should consider electrification cost curves.

Although not widely appreciated, measured smFRET efficiencies can vary depending on illumination intensity. Self-healing fluorophores offer robust triplet state suppression to enable accurate smFRET measurements under broad illumination regimes.

Quantum error correction protocols aim at protecting quantum information from corruption due to decoherence and imperfect control. Using three superconducting transmon qubits, Chow et al. demonstrate necessary elements for the implementation of the surface error correction code on a two-dimensional lattice.

Measurements of the spin susceptibility in a model cuprate reveal the presence of two distinct gaps underlying the pseudogap behaviour. One gap is attributed to charge density waves and the other to the predicted formation of spin singlets.

Here, Miranda-Cervantes et al. identified pantothenate kinase 4 (PanK4) as a key regulator of muscle metabolism. Deleting PanK4 impairs fatty acid oxidation and glucose uptake, leading to glucose intolerance, while increasing PanK4 enhances glucose metabolism, highlighting its potential in promoting metabolic health.

Vibrational energy transfer (VET) is essential for protein function as it is responsible for efficient energy dissipation in reaction sites and is linked to pathways of allosteric communication. Here authors equipped a tryptophan zipper with a VET injector and a VET sensor for femtosecond pump probe experiments to map the VET.

Although co-occurring species may differ widely in their response traits, coordinated functional trait shifts may emerge at the community level in response to environmental factors. Here, the authors use data from 150 grassland sites to identify a coordinated slow-fast strategy response to land-use intensification across above- and belowground taxa.

Electrical transport measurements reveal that Co₃Sn₂S₂ is probably a magnetic Weyl semimetal, and hosts the highest simultaneous anomalous Hall conductivity and anomalous Hall angle. This is driven by the strong Berry curvature near the Weyl points.