Nature Search

Cooperation of chromatin remodeling SWI/SNF complex and pioneer factor AP-1 shapes 3D enhancer landscapes

The mechanism controlling SWI/SNF chromatin remodeler targeting is incompletely understood. This study demonstrates that AP-1 transcription factors guide SWI/SNF to genomic regions, resulting in 3D genomic architecture alterations.

Bennett K. Wolf
Yanding Zhao
Xiaofeng Wang
Research15 Dec 2022
Nature Structural & Molecular Biology

Volume: 30, P: 10-21
Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals

Genetic elements that control inflammatory gene expression are not fully elucidated. Here the authors conduct a multi-species analysis of chromatin landscape and NF-κB binding in response to the proinflammatory cytokine TNFα, finding that conserved NF-κB bound regions are linked to enhancer activity and disease.

Azad Alizada
Nadiya Khyzha
Michael D. Wilson
ResearchOpen Access25 Jan 2021
Nature Communications

Volume: 12, P: 1-23
Decrease in Chloroplast Content of Barley Leaves infected with Powdery Mildew

T. A. DYER
K. J. SCOTT
Research31 Mar 1972
Nature

Volume: 236, P: 237-238
Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Integration of longitudinal gut metagenomic datasets from children in Finland, Estonia and Russian Karelia reveals high strain-level diversity, which consequently impacts the functional capabilities of the early life microbiome.

Tommi Vatanen
Damian R. Plichta
Ramnik J. Xavier
Research17 Dec 2018
Nature Microbiology

Volume: 4, P: 470-479
Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease

To advance our understanding of pathological features associated with Alzheimer’s disease (AD), chemical tools with distinct specificity towards AD targets would be valuable. Here the authors used a structure-mechanism-based design strategy to obtain small molecules as chemical regulators for distinct pathological factors linked to AD pathology.

Michael W. Beck
Jeffrey S. Derrick
Mi Hee Lim
ResearchOpen Access13 Oct 2016
Nature Communications

Volume: 7, P: 1-13
Structure of the full-length TRPV2 channel by cryo-EM

Transient receptor potential (TRP) proteins are Ca²⁺-permeable cation channels activated by a range of chemical and physical stimuli. Here the authors describe a cryo-EM structure of the full-length TRPV2 channel that provides insight into the regulation of the TRPV subfamily of channels.

Kevin W. Huynh
Matthew R. Cohen
Vera Y. Moiseenkova-Bell
ResearchOpen Access29 Mar 2016
Nature Communications

Volume: 7, P: 1-8
Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment

Yuu Nishinarita
Jun Miyoshi
Tadakazu Hisamatsu
ResearchOpen Access26 May 2025
Scientific Reports

Volume: 15, P: 1-15
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

Mechanical and electrical activity in the heart is propagated through unique cardiomyocyte membrane structures, the intercalated discs (ID). Sharma et al.identify a novel ID protein, Tmem65, that controls Ca2+ signalling and electrical coupling by interacting with and functionally regulating the gap junction protein Cx43.

Parveen Sharma
Cynthia Abbasi
Anthony O. Gramolini
Research25 Sept 2015
Nature Communications

Volume: 6, P: 1-13
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism

Insulin signaling represses Forkhead transcription factor FoxO activity, which contributes to organismal metabolism. Here, the authors use proteomics to identify positively regulated insulin signaling targets FoxK1/K2 and demonstrate their role in lipid metabolism and mitochondrial regulation.

Masaji Sakaguchi
Weikang Cai
C. Ronald Kahn
ResearchOpen Access05 Apr 2019
Nature Communications

Volume: 10, P: 1-17
Avian Medullary Bone

T. G. TAYLOR
J. H. MOORE
Research12 Sept 1953
Nature

Volume: 172, P: 504-505
Dr. H. J. Hansen and the Copenhagen Museum of Zoology

W. T. CALMAN
Research10 Mar 1910
Nature

Volume: 83, P: 36
Veined Structure in Ice

T. G. BONNEY
Research27 Jan 1870
Nature

Volume: 1, P: 337
Another Variable to be observed in Autoradiographs

R. T. SIMS
Research27 Jul 1963
Nature

Volume: 199, P: 395
A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females

Girls are tenfold more likely than boys to require surgical treatment for idiopathic scoliosis, a common paediatric skeletal disorder. Here, Sharma et al. identify the first sexually dimorphic idiopathic scoliosis risk locus, and demonstrate that it may play a role in the regulation of spinal cells.

Swarkar Sharma
Douglas Londono
Carol A. Wise
ResearchOpen Access18 Mar 2015
Nature Communications

Volume: 6, P: 1-10
Gap-state engineering of visible-light-active ferroelectrics for photovoltaic applications

Overcoming the optical transparency of wide bandgap of ferroelectric oxides by narrowing its bandgap tends to result in a loss of polarization. By utilizing defect states within the bandgap, Matsuo et al. report visible-light-active ferroelectrics without sacrificing polarization.

Hiroki Matsuo
Yuji Noguchi
Masaru Miyayama
ResearchOpen Access08 Aug 2017
Nature Communications

Volume: 8, P: 1-8
The molecular basis, genetic control and pleiotropic effects of local gene co-expression

Local gene co-expression is found throughout the genome, but systematic analysis of these co-expressed genes is needed. Here, the authors identify local co-expressed genes in 49 tissues and characterize the genetic variants which may affect their expression and contribute to disease.

Diogo M. Ribeiro
Simone Rubinacci
Olivier Delaneau
ResearchOpen Access10 Aug 2021
Nature Communications

Volume: 12, P: 1-13
Dual origins of functionally distinct O-LM interneurons revealed by differential 5-HT_3AR expression

There is a diverse set of cortical interneurons that uniquely participate in the computations of large cell assemblies. Here the authors show that the same type of interneuron within the hippocampus, those projecting to the oriens-lacunosum moleculare, can have distinct developmental origins and different circuit functions.

Ramesh Chittajallu
Michael T Craig
Chris J McBain
Research06 Oct 2013
Nature Neuroscience

Volume: 16, P: 1598-1607
Effect of mineral precipitation on isotopic composition and ¹⁴C dating of groundwater

T. M. L. WIGLEY
Research01 Sept 1976
Nature

Volume: 263, P: 219-221
_D-Serine reflects kidney function and diseases

Atsushi Hesaka
Shinsuke Sakai
Tomonori Kimura
ResearchOpen Access25 Mar 2019
Scientific Reports

Volume: 9, P: 1-8
On the pseudo-hyperbolic behavior of charge transfer resistance–temperature dependence in corrosion behavior of Nickel based glass alloy

Khadijah M. Emran
Inam M. A. Omar
Noureddine Ouerfelli
ResearchOpen Access19 Apr 2022
Scientific Reports

Volume: 12, P: 1-12
Discovery of superconductivity in KTaO₃ by electrostatic carrier doping

Electrostatic doping of KTaO₃ with an electric double-layer transistor has allowed superconductivity to be observed in this material for the first time.

K. Ueno
S. Nakamura
M. Kawasaki
Research22 May 2011
Nature Nanotechnology

Volume: 6, P: 408-412
Homo- and heterodehydrocoupling of phosphines mediated by alkali metal catalysts

Catalytic transformations involving main group compounds is much less developed than carbon chemistry. Here, the authors report the use of catalytic or stoichiometric tBuOK in presence of a hydrogen acceptor for efficient P–P and P–heteroatom coupling reactions.

Lipeng Wu
Vincent T. Annibale
Ian Manners
ResearchOpen Access26 Jun 2019
Nature Communications

Volume: 10, P: 1-10
Messrs. McAipine's Atlases

T. JEFFERY PARKER
Research27 Jul 1882
Nature

Volume: 26, P: 292-293
A History of Persia

A. T. W.
Books & Arts06 Dec 1930
Nature

Volume: 126, P: 871-872
Metal-free dehydropolymerisation of phosphine-boranes using cyclic (alkyl)(amino)carbenes as hydrogen acceptors

Polymers featuring p-block elements other than carbon are of interest for a range of applications, but access to highly-substituted examples remains challenging. Here the authors demonstrate that cyclic (alkyl)(amino)carbenes can mediate the dehydropolymerisation of phosphine-boranes, leading to the construction of P-disubstituted polyphosphinoboranes.

Nicola L. Oldroyd
Saurabh S. Chitnis
Ian Manners
ResearchOpen Access26 Mar 2019
Nature Communications

Volume: 10, P: 1-9
The Andaman Islanders: A Study in Social Anthropology

R. C. T.
Books & Arts22 Jul 1922
Nature

Volume: 110, P: 106-108
CD28 co-stimulation: novel insights and applications in cancer immunotherapy

This Review covers recent advances in our understanding of CD28 co-stimulation of T cells and discusses an emerging paradigm that positions CD28 as central to the success of current and future immunotherapeutic approaches to treating cancer.

Michael T. Lotze
Scott H. Olejniczak
Dimitris Skokos
Reviews25 Jul 2024
Nature Reviews Immunology

Volume: 24, P: 878-895
A Note on Flame-Length

LEWIS T. WRIGHT
Research07 Apr 1881
Nature

Volume: 23, P: 527-528
Quantifying airborne dispersal routes of pathogens over continents to safeguard global wheat supply

Recent outbreaks of wheat stem rust pose a threat to global wheat production. A powerful computational modelling approach is now used to trace and predict the spread of these new pathogen stains, and can potentially be applied to other wind-dispersed spores.

M. Meyer
J. A. Cox
C. A. Gilligan
Research25 Sept 2017
Nature Plants

Volume: 3, P: 780-786
Effort-dependent effects on uniform and diverse muscle activity features in skilled pitching

Tsubasa Hashimoto
Ken Takiyama
Kimitaka Nakazawa
ResearchOpen Access15 Apr 2021
Scientific Reports

Volume: 11, P: 1-14
Molecular Cloning of the Vitellogenin Gene and the Effects of Vitellogenin Protein Expression on the Physiology of Harmonia axyridis (Coleoptera: Coccinellidae)

T. Zhang
G. Zhang
F. Liu
ResearchOpen Access24 Oct 2017
Scientific Reports

Volume: 7, P: 1-9
The Sperm Whale and its Food

FRANK T. BULLEN
Editorial04 Jun 1896
Nature

Volume: 54, P: 102-103
Control of plant stem cell function by conserved interacting transcriptional regulators

Here, plant HAM proteins are shown to physically interact with the transcription factor WUSCHEL and the related WOX proteins, with this interaction driving downstream transcriptional programs and determining the activities of stem cells.

Yun Zhou
Xing Liu
Elliot M. Meyerowitz
Research26 Oct 2014
Nature

Volume: 517, P: 377-380
Protein tyrosine phosphatases and the immune response

Tomas Mustelin
Torkel Vang
Nunzio Bottini
Reviews01 Jan 2005
Nature Reviews Immunology

Volume: 5, P: 43-57
Symmetry-protected topological exceptional chains in non-Hermitian crystals

Exceptional points are of great importance to rationalize the topological properties of non-Hermitian systems. This study proposes a new class of non-Hermitian topological degeneracies named exceptional chains, and develops a general theory to understand such non-Hermitian crystalline system by merging non-Hermitian and topological fields.

Ruo-Yang Zhang
Xiaohan Cui
C. T. Chan
ResearchOpen Access08 Jul 2023
Communications Physics

Volume: 6, P: 1-12
Infrared laser–induced gene expression in single cells characterized by quantitative imaging in Physcomitrium patens

A study optimizes a system effectively inducing gene expression by infrared laser heating and characterizes the induction profile of single cells in the different conditions through quantitative imaging analysis in the moss Physcomitrium patens.

Takumi Tomoi
Yuka Yoshida
Yasuhiro Kamei
ResearchOpen Access06 Nov 2024
Communications Biology

Volume: 7, P: 1-12
Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor

The cancer drug rocaglamide A cements the RNA helicase eIF4A on polypurine sequences and thereby prevents scanning of the 43S subunit along the messenger RNA, highlighting how a drug can act by stabilizing sequence-selective RNA–protein interactions.

Shintaro Iwasaki
Stephen N. Floor
Nicholas T. Ingolia
Research15 Jun 2016
Nature

Volume: 534, P: 558-561
Experimental maturation of pine resin in sediment to investigate the formation of synthetic copal and amber

Evan T. Saitta
Thomas G. Kaye
ResearchOpen Access24 Mar 2025
Scientific Reports

Volume: 15, P: 1-18
Frequency-modulated timer regulates torpor–arousal cycles during hibernation in distinct small mammalian hibernators

Shingo Gibo
Yoshifumi Yamaguchi
Gen Kurosawa
ResearchOpen Access02 Jul 2024
npj Biological Timing and Sleep

Volume: 1, P: 1-12
The N400 effect captures nuances in implicit political preferences

Emmanuel Mahieux
Lee de-Wit
Nicole Y. Y. Wicha
ResearchOpen Access20 Jul 2024
Scientific Reports

Volume: 14, P: 1-17
Hypoxia- and Postirradiation reoxygenation-induced HMHA1/ARHGAP45 expression contributes to cancer cell invasion in a HIF-dependent manner

Peter W. T. Lee
Tatsuya Suwa
Hiroshi Harada
ResearchOpen Access13 May 2024
British Journal of Cancer

Volume: 131, P: 37-48
'Blue ostriches' captured

P. V. Tobias
T. A. Dowson
J. D. Lewis-Williams
Correspondence16 Jul 1992
Nature

Volume: 358, P: 185
Mechanism in External Field-mediated Trapping of Bacteria Sensitive to Nanoscale Surface Chemical Structure

Shiho Tokonami
Emi Shimizu
Takuya Iida
ResearchOpen Access30 Nov 2017
Scientific Reports

Volume: 7, P: 1-12
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

Here it is shown that epithelia extrude live but not dying cells at sites of high strain, elucidating a mechanism for maintaining homeostatic cell numbers.

George T. Eisenhoffer
Patrick D. Loftus
Jody Rosenblatt
Research15 Apr 2012
Nature

Volume: 484, P: 546-549
Unravelling the association of partial T-cell immunodeficiency and immune dysregulation

Surprisingly, and somewhat counter-intuitively, partial T-cell immunodeficiencies are commonly associated with hyper-immune dysregulation. Here, the authors review the genetic basis of such immunodeficiencies and draw on mouse models to provide a potential explanation for the coexistence of immunodeficiency and autoimmunity.

Adrian Liston
Anselm Enders
Owen M. Siggs
Reviews01 Jul 2008
Nature Reviews Immunology

Volume: 8, P: 545-558
EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells

Seiko Yoshino
Yusuke Matsui
Takeharu Sakamoto
ResearchOpen Access09 Jun 2020
Scientific Reports

Volume: 10, P: 1-15
Dynamic multilevel spiral phase plate generator

M. Caño-García
X. Quintana
M. A. Geday
ResearchOpen Access25 Oct 2018
Scientific Reports

Volume: 8, P: 1-8
Identification of cadaveric liver tissues using thanatotranscriptome biomarkers

Gulnaz T. Javan
Erin Hanson
Jack Ballantyne
ResearchOpen Access20 Apr 2020
Scientific Reports

Volume: 10, P: 1-8
Report of the Working and Results of the Woburn Experimental Fruit Farm

MAXWELL T. MASTERS
Books & Arts20 Dec 1900
Nature

Volume: 63, P: 177-178
Feature engineering descriptors, transforms, and machine learning for grain boundaries and variable-sized atom clusters

C. Braxton Owens
Nithin Mathew
Eric R. Homer
ResearchOpen Access26 Jan 2025
npj Computational Materials

Volume: 11, P: 1-15

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