Nature Search

Generation of Human Epidermis-Derived Mesenchymal Stem Cell-like Pluripotent Cells and their reprogramming in mouse chimeras

Bing Huang
KaiJing Li
Jian Ge
ResearchOpen Access08 Jun 2011
Nature Precedings

P: 1
First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

In a prespecified interim analysis of the randomized, double-blind phase 3 COMPASSION-15 trial, patients with advanced HER2-negative gastric/GEJ cancer treated with the anti-PD-L1/CTLA-4 bispecific Ab cadonilimab plus chemotherapy showed significantly improved overall survival compared with patients treated with placebo plus chemotherapy as first-line treatment.

Lin Shen
Yanqiao Zhang
Jiafu Ji
Research22 Jan 2025
Nature Medicine

Volume: 31, P: 1163-1170
Large language model-based biological age prediction in large-scale populations

Using data from six population-scale cohorts involving more than 10 million individuals, a large language model-based aging signature is shown to outperform traditional aging biomarker indices and signatures in predicting multiple health outcomes, at general and organ-specific levels.

Yanjun Li
Qi Huang
Qian Di
Research23 Jul 2025
Nature Medicine

Volume: 31, P: 2977-2990
Maternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis

Early life experience modulates stress resilience in later life. Here the authors show that maternal care triggers microglia-derived IGF-1 levels, which suppresses the neuronal C/EBPβ-DRP1 axis, promoting stress resilience in adolescent mice.

Hongyu Chen
Ruifeng Xu
Zhi-Hao Wang
ResearchOpen Access08 Mar 2025
Nature Communications

Volume: 16, P: 1-27
Mechano-gated iontronic piezomemristor for temporal-tactile neuromorphic plasticity

In this work, authors develop a mechano-gated iontronic piezomemristor with temporal-tactile neuromorphic plasticity, enabling bidirectional sensing, learning functions, and biohybrid integration for dynamic tactile neuromodulation.

Xiao Wei
Zhixin Wu
Ziguang Zhao
ResearchOpen Access26 Jan 2025
Nature Communications

Volume: 16, P: 1-10
Understanding atmospheric processes: insights from the comparison between Beijing and Hyytiälä

Markku Kulmala
Du Wei
Tom Kokkonen
ResearchOpen Access16 Sept 2025
npj Clean Air

Volume: 1, P: 1-21
Author Correction: First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

Lin Shen
Yanqiao Zhang
Jiafu Ji
Amendments and Corrections26 Mar 2025
Nature Medicine

Volume: 31, P: 1368
Highly branched poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells

Therapeutics delivery by using non-viral vectors presents several challenges in the design of an appropriate polymeric structure. Here, the authors report a series of highly branched, biodegradable polymers which show high transfection efficiency in human multipotent adipose derived stem cells and primary astrocytes.

Shuai Liu
Yongsheng Gao
Wenxin Wang
ResearchOpen Access24 Jul 2019
Nature Communications

Volume: 10, P: 1-14
DNMBP-AS1/hsa-miR-30a-5p/PGC1α axis suppresses tumor progression of colorectal cancer by inhibiting PKM2-mediated Warburg effect and enhance anti-PD-1 therapy efficacy

Tianxiao Wang
Wenxin Zhang
Qunyi Li
ResearchOpen Access02 Jul 2025
Cell Death Discovery

Volume: 11, P: 1-19
Deformation characteristics of solid-state benzene as a step towards understanding planetary geology

Solid benzene and other simple organic minerals play important roles in geological processes on Titan-like cold Solar System bodies. Here, the authors discover benzene microcrystals plastically deform via densification enabled by molecule reorientation and shearing.

Wenxin Zhang
Xuan Zhang
Julia R. Greer
ResearchOpen Access26 Dec 2022
Nature Communications

Volume: 13, P: 1-10
NSD2 promotes cell durotaxis and drives the transition from polycystic kidney disease to tubulocystic renal cell carcinoma through integrin/FAK/AKT signaling

Wenxin Feng
Ningyuan Liu
Li Li
Research22 Jul 2025
Oncogene

Volume: 44, P: 3437-3448
Operando monitoring of thermal runaway in commercial lithium-ion cells via advanced lab-on-fiber technologies

Operando monitoring of thermal runaway in Li-ion batteries is critical. Here, authors develop an optical fiber sensor capable of insertion into 18650 batteries to monitor internal temperature and pressure during thermal runaway, facilitating battery safety assessment and early warning capability.

Wenxin Mei
Zhi Liu
Tuan Guo
ResearchOpen Access29 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Advancement of technology towards developing perovskite-based solar cells for renewable energy harvesting and energy transformation applications

Mohammed-Ibrahim Jamesh
Haihang Tong
Hsien-Yi Hsu
ReviewsOpen Access06 Sept 2025
npj Materials Sustainability

Volume: 3, P: 1-46
6mA-DNA-binding factor Jumu controls maternal-to-zygotic transition upstream of Zelda

N6-methyladenine (6mA) DNA modification is a dynamic epigenetic mark in Drosophila embryos, but how 6mA is decoded is unclear. Here, the authors show that the protein Jumu binds 6mA-marked DNA to regulate the maternal-to-zygotic transition, partly through regulation the expression of the 6mA marked pioneer factor zelda.

Shunmin He
Guoqiang Zhang
Dahua Chen
ResearchOpen Access17 May 2019
Nature Communications

Volume: 10, P: 1-14
Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF

Diheme-containing succinate:menaquinone oxidoreductases (Sdh) are members of the complex II superfamily. Here, the authors present the 2.8 Å cryo-EM structure of Mycobacterium smegmatis Sdh2, which reveals membrane-anchored SdhF as a component of the complex and they discuss the electron/proton transfer pathway in the Sdh2 trimer.

Hongri Gong
Yan Gao
Zihe Rao
ResearchOpen Access25 Aug 2020
Nature Communications

Volume: 11, P: 1-8
Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Intestinal microbiota alterations may affect heart function through the production of gut-derived metabolites. Here the authors found that gut microbiota-derived TMAVA is a key determinant for the development of cardiac hypertrophy through inhibition of carnitine synthesis and subsequent fatty acid oxidation.

Mingming Zhao
Haoran Wei
Lemin Zheng
ResearchOpen Access01 Apr 2022
Nature Communications

Volume: 13, P: 1-18
A lightweight large receptive field network LrfSR for image super-resolution

Wanqin Wang
Shengbing Che
Zixuan Zhang
ResearchOpen Access11 Apr 2025
Scientific Reports

Volume: 15, P: 1-19
Aqueous microdroplets promote C–C bond formation and sequences in the reverse tricarboxylic acid cycle

Using aqueous microdroplets to study reactions in the reverse tricarboxylic acid cycle (rTCA), the authors show rapid carbon fixation through reductive carboxylation reactions at ambient temperature, without requiring enzymes or metal catalysts, suggesting that microdroplets might have facilitated a non-enzymatic version of the rTCA cycle in prebiotic carbon anabolism.

Yun Ju
Hong Zhang
Jie Jiang
Research07 Sept 2023
Nature Ecology & Evolution

Volume: 7, P: 1892-1902
Neural dynamics of racial categorization predicts racial bias in face recognition and altruism

Zhou et al. use multimodal brain imaging measures to describe the neural dynamics of same-race and other-race facial categorization. The resulting dynamic neural activity predicts racial biases in facial recognition and altruistic intention.

Yuqing Zhou
Tianyu Gao
Shihui Han
Research07 Oct 2019
Nature Human Behaviour

Volume: 4, P: 69-87
Age-Period-Cohort Analysis of HIV Mortality in China: Data from the Global Burden of Disease Study 2016

Disi Gao
Zhiyong Zou
Yinghua Ma
ResearchOpen Access27 Apr 2020
Scientific Reports

Volume: 10, P: 1-8
Dynamic FMR1 granule phase switch instructed by m6A modification contributes to maternal RNA decay

Maternal RNA degradation is critical for embryogenesis and is tightly controlled by maternal RNA-binding proteins. Here the authors show that a subset of m6A-modified mRNAs regulates the dynamics of RNA-granules, thus contributes to maternal mRNA decay.

Guoqiang Zhang
Yongru Xu
Dahua Chen
ResearchOpen Access14 Feb 2022
Nature Communications

Volume: 13, P: 1-16
LINC00654 promotes ovarian cancer progression by facilitating nuclear export of HuR and stabilizing oncogenic mRNAs

Cong Shen
Ruican Cao
Ting Wang
Research22 Jul 2025
Oncogene

Volume: 44, P: 3422-3436
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy

A selective and potent CDK2 degrader was developed that induced differentiation of acute myeloid leukemia cell lines and primary patient cells.

Liguo Wang
Xuejing Shao
Yu Rao
Research04 Mar 2021
Nature Chemical Biology

Volume: 17, P: 567-575
DSF-YOLO for robust multiscale traffic sign detection under adverse weather conditions

Jun Li
QinWen Deng
HaiBo Pu
ResearchOpen Access08 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Author Correction: Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF

Hongri Gong
Yan Gao
Zihe Rao
Amendments and CorrectionsOpen Access23 Feb 2021
Nature Communications

Volume: 12, P: 1
Complex polymer architectures through free-radical polymerization of multivinyl monomers

During free-radical polymerization of multivinyl monomers, the regulation of intermolecular crosslinking and intramolecular cyclization enables the construction of complex polymer architectures. This Review summarizes methods to achieve this control and techniques to analyse the sub-chain connections. Finally, it discusses exemplary biomedical applications of the complex polymer products.

Yongsheng Gao
Dezhong Zhou
Wenxin Wang
Reviews23 Mar 2020
Nature Reviews Chemistry

Volume: 4, P: 194-212
Comparison of [^99mTc]Tc-FAPI SPECT/CT and [¹⁸F]FDG PET/CT as predictive biomarkers for immunotherapy response in gastrointestinal cancer

Yu Zhang
Hong Chen
Wenxin Chen
ResearchOpen Access14 May 2025
Scientific Reports

Volume: 15, P: 1-11
Multispectral smart window: Dynamic light modulation and electromagnetic microwave shielding

A novel multispectral smart window achieves dynamic light modulation and robust microwave shielding.

Ruicong Zhang
Zicheng Song
Jiaqi Zhu
ResearchOpen Access30 Aug 2024
Light: Science & Applications

Volume: 13, P: 1-11
Inducing and exploiting vulnerabilities for the treatment of liver cancer

CDC7 inhibition selectively induces senescence in hepatocellular carcinoma cells with TP53 mutations, which enables the selective apoptotic cell death of these senescent cells using inhibitors of mTOR signalling.

Cun Wang
Serena Vegna
René Bernards
Research02 Oct 2019
Nature

Volume: 574, P: 268-272
CTCF enhances pancreatic cancer progression via FLG-AS1-dependent epigenetic regulation and macrophage polarization

Yihao Liu
Pengyi Liu
Baiyong Shen
Research30 Nov 2024
Cell Death & Differentiation

Volume: 32, P: 745-762
Optimizing bus charging infrastructure by incorporating private car charging demands and uncertain solar photovoltaic generation

Xiaolei Ma
Wenxin Ma
Xiaohan Liu
ResearchOpen Access03 Feb 2025
npj Sustainable Mobility and Transport

Volume: 2, P: 1-13
Collaborative optimization of depot location, capacity and rolling stock scheduling considering maintenance requirements

Qingwei Zhong
Yingxue Yu
Xu Yan
ResearchOpen Access27 Mar 2024
Scientific Reports

Volume: 14, P: 1-18
Revealing an unprecedented diversity of episymbiotic Saccharibacteria in a high-quality genome collection

Wenxin He
Hewei Liang
Yuanqiang Zou
ResearchOpen Access19 Dec 2024
npj Biofilms and Microbiomes

Volume: 10, P: 1-11
A distinct giant coat protein complex II vesicle population in Arabidopsis thaliana

The coat protein complex II (COPII) is a type of specialized vesicle coat protein that mediates vesicle trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus. A population of giant COPII vesicles is identified and shown to be produced in response to the plant hormone abscisic acid (ABA) and abiotic stresses in Arabidopsis.

Baiying Li
Yonglun Zeng
Liwen Jiang
Research07 Oct 2021
Nature Plants

Volume: 7, P: 1335-1346
LINC01320 facilitates cell proliferation and migration of ovarian cancer via regulating PURB/DDB2/NEDD4L/TGF-β axis

Gaigai Wang
Bingya Xu
Cong Shen
ResearchOpen Access31 Oct 2024
Scientific Reports

Volume: 14, P: 1-13
Author Correction: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

Sanjay Jain
Liming Pei
Michael P. Snyder
Amendments and Corrections01 Mar 2024
Nature Cell Biology

Volume: 26, P: 839
Long-term efficacy of Waveflex semi-rigid-dynamic-internal-fixation system in delaying intervertebral disc degeneration at adjacent segments and improving spinal sagittal imbalance

Wenxin Gao
Xiaoying Wang
Yanke Hao
ResearchOpen Access07 May 2024
Scientific Reports

Volume: 14, P: 1-14
SPOP mutations promote tumor immune escape in endometrial cancer via the IRF1–PD-L1 axis

Kun Gao
Qing Shi
Xiaoping Wan
Research08 Dec 2022
Cell Death & Differentiation

Volume: 30, P: 475-487
Phosphorylation of INF2 by AMPK promotes mitochondrial fission and oncogenic function in endometrial cancer

Yan Ding
Zeheng Lv
Kun Gao
ResearchOpen Access17 Jan 2024
Cell Death & Disease

Volume: 15, P: 1-11
Shared biomarkers and immune cell infiltration signatures in ulcerative colitis and nonalcoholic steatohepatitis

Wenxin Wang
Xin Gao
Xiaolan Zhang
ResearchOpen Access28 Oct 2023
Scientific Reports

Volume: 13, P: 1-16
Ketohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction

Yansong Li
Tao Jiang
Qiang Wang
ResearchOpen Access01 Nov 2023
Experimental & Molecular Medicine

Volume: 55, P: 2417-2432
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

The Human BioMolecular Atlas Program (HuBMAP) presents its production phase: the generation of spatial maps of functional tissue units across organs from diverse populations and the creation of tools and infrastructure to advance biomedical research.

Sanjay Jain
Liming Pei
Michael P. Snyder
Reviews19 Jul 2023
Nature Cell Biology

Volume: 25, P: 1089-1100
High performance visible-SWIR flexible photodetector based on large-area InGaAs/InP PIN structure

Xuanzhang Li
Junyang Zhang
Hong Chen
ResearchOpen Access10 May 2022
Scientific Reports

Volume: 12, P: 1-11
Functional identity enhances aboveground productivity of a coastal saline meadow mediated by Tamarix chinensis in Laizhou Bay, China

Shijie Yi
Pan Wu
Weihua Guo
ResearchOpen Access02 Apr 2020
Scientific Reports

Volume: 10, P: 1-9
Monocyte infiltration and proliferation reestablish myeloid cell homeostasis in the mouse retina following retinal pigment epithelial cell injury

Wenxin Ma
Yikui Zhang
Wai T. Wong
ResearchOpen Access16 Aug 2017
Scientific Reports

Volume: 7, P: 1-18
Head-to-head comparison of ^99mTc-PSMA and ^99mTc-MDP SPECT/CT in diagnosing prostate cancer bone metastasis: a prospective, comparative imaging trial

Yu Zhang
Zhiyi Lin
Wenxin Chen
ResearchOpen Access26 Sept 2022
Scientific Reports

Volume: 12, P: 1-11
A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma

Cun Wang
Haojie Jin
René Bernards
Correspondence05 Mar 2018
Cell Research

Volume: 28, P: 690-692
DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells

Hongshan Guo
Boqiang Hu
Jie Qiao
ResearchOpen Access08 Nov 2016
Cell Research

Volume: 27, P: 165-183

Search

Filter By:

Search

Quick links