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The efficiency of perovskite/organic tandem devices is impeded by recombination losses that occur within the organic subcells. Here, the authors monitor film growth and crystallization dynamics in real-time and mitigate exciton recombination losses, achieving maximum device efficiency of 26.42%.

Structural and functional understanding of the afferent inputs to histaminergic neurons remains incomplete and lacks systematic characterization. Herein, the authors establish a comprehensive and precise whole-brain atlas of long-range inputs to mouse histaminergic neurons and investigate the representative upstream histaminergic neural circuits in regulating the sleep-wake cycle.

Siltartoxatug, a first-in-class recombinant monoclonal antibody for tetanus prophylaxis, was shown to be safe and superior to plasma-derived human tetanus immunoglobulin in achieving anti-tetanus neutralizing antibody titers 12 hours after administration.

The advent of isolated attosecond XUV pulse sources marks a new era in attosecond science, pivotal for the investigation of core electron dynamics. Here the authors discover that the coherent Raman coupling between the cation states leads to extra timedelay between different transition channels by applying the attosecond transient absorption spectroscopy on the investigation of complex dynamics of strong field ionization of Krypton.

Discectomy-induced ferroptosis of nucleus pulposus cells (NPCs) contributes to postoperative intervertebral disc degeneration (IDD). Here, Wang et al. report a therapeutic strategy employing ECM-mimetic hydrogel fillers for delivering NPC-derived exosomes to combat ferroptosis-induced IDD.

Neural mechanism underlying fear memory process is not fully understood. Here, the authors report that histamine H₁ receptor (H₁R) in medial septum cholinergic neurons is critical for contextual fear retrieval, serving as a promising target for related neurological disease.

Characterization of the solid electrolyte interphase formed on Li-ion battery electrodes presents significant experimental challenges. Here the authors use atomic force microscopy-based force-spectroscopy techniques to depict the initial interphase formation in two different electrolyte classes.

Metabolism is known to be linked to lifespan in some species, though it remains unclear how this effect is mediated. Here they show that reduced pyruvate dehydrogenase (PDH) activity lowers locomotion but extends lifespan in daphnids and show that inhibition of PDH can increase lifespan in these species.

Researchers demonstrate a monolithically integrated four-spin optical Ising machine using optoelectronic coupled oscillators. The system achieves high efficiency (4 mW per unit), fast spin evolution (150 ns), and reconfigurable coupling, advancing scalable optical computing.

Here, the authors employed 19 F NMR and Gaussian accelerated MD simulations to determine the conformational landscape of the adenosine-A2A receptor and mini-Gαsβγ complex, enabling determination of an intermediate structure of the complex with cryoEM.

Enhancing the transport properties of surface states in topological insulators is vital if they are to be incorporated into practical devices. Towards this end, Chen et al. study the transport in aged (Cu_0.1Bi_0.9)₂Te_3.06, where the ageing process suppresses bulk conductance by up to four orders of magnitude.

Thick film is preferred for sufficient light absorption and tolerant processing but it easily spoils the charge transport in the all-polymer solar cells. Here Fan et al. reconcile by tuning the film morphology and deliver high efficiency of 10% in 1 cm² area devices.

Sequencing and de novo assembly of seven wild relatives of soybean yields insights relevant to crop domestication and improvement.

Soil organic carbon stocks above 1 m increased from 68.40 Pg to 70.33 Pg, exhibiting a multi-stage change of “rising-fluctuating” for the last 60 years across the Contiguous United States, according to a spatial-temporal analysis of soil organic carbon dataset spanning from 1955 to 2014.

SARS-CoV-2’s rapid evolution threatens public health. Here, authors present a deep learning approach to forecast high-risk mutations that may appear in the future, aiding vaccine development and enhancing preparedness against future variants.

Energetic traps accumulation aroused by thermal stress is a critical issue in organic solar cells. Here, authors integrate a wide bandgap polymer and two non-fullerene acceptors with different thermal and morphological properties, realizing a promising efficiency of 18.26% and long device stability.

A water harvesting strategy utilizing a hygroscopic lithium chloride impregnated cellulose scaffold yields high water harvesting rate with low energy input over a wide range of relative humidity. The strategy, reported by Wenkai Zhu, Yun Zhang, Chi Zhang and coworkers, provides a potential solution to the global water scarcity problem particularly in arid areas.

Two draft sequences of Gossypium hirsutum, the most widely cultivated cotton species, provide insights into genome structure, genome rearrangement, gene evolution and cotton fiber biology.

An introgression platform for transferring genetic variations of Aegilops tauschii to hexaploid wheat is established based on synthetic octoploid wheat. Combined with newly generated genome resources of A. tauschii, it represents a powerful tool for wheat gene discovery and breeding.

Spatial omics technologies require alignment and stitching of slices for a 3D molecular profile. Here, the authors present SANTO, a coarse-to-fine method that rapidly determines spatial positions and overlap regions, then refines them, enabling integration across platforms and modalities.

Spin-polarized lasers have demonstrated many superiorities over conventional lasers. Here the authors report the identification and successful suppression of the spin relaxation mechanism in perovskites for the experimental realization of spin-polarized perovskite lasers.

The genome of the scallop Patinopecten yessoensis is sequenced. This bivalve mollusc has a slow-evolving genome with features such as karyotype and Hox gene expression that may be close to that of the ancestral bilaterian.

Gold nanoclusters show promise as photothermal materials, but are often thermally unstable. Here ligand engineering is used to integrate molecular rotors with gold nanoclusters to dissipate thermal energy and improve photothermal therapy performance.

Based on differently-oriented MAPbBr3 single-crystal wafers, the authors revealed anisotropic carrier dynamics by using angle-resolved pump-probe technique, and the microstructural mechanism of the femtosecond laser-induced emission enhancement

Historical velocity maps reveal over five decade-long acceleration and high-level discharge in Totten Glacier, East Antarctica, from 1963-2018, induced by warm modified Circumpolar Deep Water.

Reducing non-radiative energy loss is critical to improving power conversion efficiency in organic solar cells. Jiang et al. show that alkyl side-chain engineering in acceptors reduces the free volume ratio, lowering non-radiative decay, to achieve 18.6% efficiency in bulk-heterojunction binary cells.

Molecular design is key to the power conversion efficiency in organic photovoltaics. Jiang, Sun, Xu et al. develop a non-fullerene acceptor with asymmetric structure and phenyl-substituted side chains that minimizes photon and carrier losses, enabling 20.2% efficiency.

Ming Li, Ruiqiang Li and colleagues report the whole-genome sequencing of a male golden snub-nosed monkey, Rhinopithecus roxellana, as well as its relatives Rhinopithecus bieti, Rhinopithecus brelichi and Rhinopithecus strykeri. Their analysis provides insights into primate evolution and adaptation to a diet consisting primarily of leaves and seeds.

Improvement in sample quality has resulted in the first observation of the quantum Hall effect in a black phosphorus two-dimensional electron system.

Optical control is an alternative pathway to boost nonlinear transport in noncentrosymmetric systems. Here, the authors observe a light-induced giant enhancement of nonreciprocal transport coefficient as high as 10⁵A⁻¹ T⁻¹ at KTaO₃-based Rashba interfaces.

The dynamics of planted forests in China over the past three decades have contributed ~1198tg of above-ground carbon storage.

A large light-receiving angle in planar solar cells is crucial for flexible installation of distributed photovoltaics. Here, authors report sequential-processed all-polymer solar cells with nano-sized phase separation integrated in micro-sized surface topology and maximum efficiency of over 19%.

The morphology of donor–acceptor blends in organic photovoltaics dictates the efficiency of the exciton dissociation and charge diffusion, and thus the final device performance. Here, the authors show that filament assembly helps to maximize the output, further enabling a power conversion efficiency greater than 19%.

This work reports a self-polymerization confinement strategy to develop and synthesize carbon-supported metal catalysts with high metal loading. Efficient Fenton reactivity is observed for samples containing well dispersed iron sites.

The Indian and East Asian summer monsoons are found to be synchronized at the subseasonal timescale via a Rossby wave triggered by the Indian summer monsoon heating. The impact on East Asian precipitation varies with the subtropical jet structure.

The results of the Fifth RNA-Puzzles contest highlights advances in RNA three-dimensional structure prediction and uncovers new insights into RNA folding and structure.

Gastrodia elata is an obligate mycoheterotrophic plant with highly reduced leaves and bracts in scape. Here, Yuan et al sequence and analyze its 1.06 Gb genome which provides insights in adaptation to a lifestyle of heterotrophy.

Materials design rules play a key role in enabling high performance in organic photovoltaics. Here the authors achieve 12.25% efficiency on 1 cm² non-fullerene solar cells by tuning the side chains’ branching point and the fluorine substitutions in donor and acceptor materials.

The wild grass Aegilops tauschii is a wheat progenitor. A high-quality genome sequence, along with methylome and transcriptome data, provides insights on domestication and the effect of transposons, and offers a resource for wheat improvement.

CARPID uses CRISPR technology to navigate biotin ligase to specific lncRNAs, which allows proximal labeling and thus the querying of RNA–protein interactions in living cells.

The atmospheric response to subseasonal variability of Tibetan Plateau snow cover has been largely ignored. Here the authors show that the fast subseasonal variability of Tibetan Plateau snow cover is closely related to the subsequent East Asian atmospheric circulation at medium-range time scales.