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Terahertz absorption reduces the viscosity of the hydrodynamic electron fluid in graphene and thereby enables easier flow of electrons. This results in a drop in resistance within graphene constrictions under terahertz radiation, facilitating fast and sensitive terahertz detection.

The SARS-CoV-2 JN.1 lineage spread rapidly in winter 2023-24 with high estimated levels of transmission but limited increase in severe disease burden. Here, the authors use electronic health record data from the United States to investigate the immune history and clinical outcomes of patients infected with this strain.

Coherent quantum transition spectroscopy of the spin of a single antiproton is reported, demonstrating Rabi oscillations of the spin and enabling improved measurement of matter/antimatter symmetry using proton and antiproton magnetic moments.

Persistent spin texture (PST) can generate fascinating physics that is promising for spintronics applications but requires non-trivial sample design. Here the authors alternatively propose that a class of materials has intrinsic PST enforced by the nonsymmorphic space group symmetry of the crystal.

A series of early-time, multiwavelength observations of an optical transient, AT2022cmc, indicate that it is a relativistic jet from a tidal disruption event originating from a supermassive black hole.

Quantum computing platforms allowing quantum error correction usually rely on complex redundant encoding within multiple two-level systems. Here, instead, the authors realize a CNOT gate between two qubits encoded in the multiphoton states of two microwave cavities nonlinearly coupled by a transmon.

Frustration-induced dimensional reduction is manifested in lower dimensionality of magnetic correlations compared to that of the magnetic structure. Here the authors demonstrate the role of the uniform Dzyaloshinskii-Moriya interaction in the recently synthesized material Ca3ReO5Cl2 exhibiting dimensional reduction.

Mid-Holocene and the future warming induces a North Pacific response resulting in sustained winter precipitation deficits and drought over the Southwestern United States, according to new palaeoclimate data and climate model simulations.

Silicon-based spin qubits are promising candidates for a scalable quantum computer. Here the authors demonstrate the violation of Bell’s inequality in gate-defined quantum dots in silicon, marking a significant advancement that showcases the maturity of this platform.

Cortical neurons comprising an output pathway form a specialized population code that enhances the propagation of information to a downstream target, potentially improving the accuracy of decision-making.

Sexual reproduction introduces genetic conflict between family members, but direct empirical evidence is lacking. Here, the authors show, in an insect with maternal care, that genetic trade-offs that differ in shape across offspring stages affect the scope for parent–offspring conflict.

Here, the authors show that van der Waals isotopic heterostructures based on few-layer h¹⁰BN and h¹¹BN can be tuned to modulate the energy-momentum dispersions of hyperbolic phonon polaritons, offering an alternative approach to engineer the nanophotonic properties of 2D materials.

A deep-learning algorithm that removes patient-identifying information from facial images, while retaining sufficient information for accurate disease diagnosis, has the potential to protect patient privacy and facilitate public acceptance of facial imaging for use in digital medicine.

The emission of entangled photon pairs from layered materials is attractive for quantum applications, but its observation in monolayers has remained elusive. Here, the authors report co- and counter-propagating photon pair emission in the telecom range from monolayer GaSe and the observation of high-fidelity Bell states in the counterpropagating configuration.

Synchrotron and inverse-Compton emission provide evidence for a reverse-shock origin of the high-energy emission from a gamma-ray burst, GRB 180720B. The polarization of the optical emission originating from the reverse shock suggests a turbulent shock that is amplified by the magnetic field in the relativistic ejecta.

Understanding the mechanisms underlying the survival of drug tolerant persister cells following chemotherapy remains elusive. Here, multi-omics analysis and experimental approaches show that the germ-cell-specific H3K4 methyltransferase PRDM9 promotes metabolic rewiring in glioblastoma stem cells.

Bidirectional neural interface electronic devices offer therapeutic options. Here, the authors present wafer-scale fabrication of flexible nanoporous graphene-based implantable microelectrode arrays with low impedance and high charge injection for in vivo brain recording and nerve stimulation.

Vortices in an electron fluid are directly observed in a para-hydrodynamic regime in which the spatial diffusion of electron momenta is enabled by small-angle scattering rather than electron–electron scattering.

Pathological B-cell receptor (BCR) signaling is a key driver of mantle cell lymphoma tumorigenesis. Here, the authors discover that CEACAM1, an immunoglobulin-like transmembrane protein, is essential for a subset of mantle cell lymphoma through activation of the BCR.

Flexible organic memory devices are promising candidates for data storage applications. Here, Ji et al.develop a flexible all-organic 64-bit memory cell array possessing one diode–one resistor architecture, which can maintain its memory characteristics even under large mechanical distortions.

Devices that generate electricity from electric fluctuations are promising for wireless power transmission as well as energy harvesting from environmental radio waves. Here the authors report the electric power generation from environmental fluctuations by using superconducting vortex strings in MoGe/YIG bilayer system.

Polaritonic Fourier crystal provides harmonic modulation of the polariton momentum in a pristine polaritonic waveguide. Authors employ hexagonal boron nitride and near-field imaging to probe Bloch waves of phonon-polaritons in the Fourier crystal.

Screening combinatorial mutants is too massive for wet-lab experiment alone. Here the authors present a machine learning-coupled combinatorial mutagenesis approach to vastly reduce experimental burden for engineering Cas9 genome editing enzymes.

Squeezed light allows for quantum-enhanced, sub-shot-noise sensing, but its generation and use on a chip has so far remained elusive. Here, the authors fill this gap by demonstrating a thin-film lithium-niobate-based integrated quantum optical sensor, which beats shot-noise-limited SNR by ~ 4%.

The mechanism of macrophage cytotoxicity against cancer cells requires further illustration. By employing CRISPR screening in CAR-macrophage and cancer cell co-culture system, the authors identify depletion of ATG9A on cancer cells sensitizes them to macrophage-mediated killing, which can be synergic with CSF1R inhibition in cancer treatment.

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

The polar chiral texture of the vortex or skyrmion structure in ferroelectric oxide PbTiO₃/SrTiO₃ superlattice attracts attention. Here, the authors report a theoretical framework to probe emergent chirality of electrical polarization textures.

Dnmt1-deficient mice show shortened long bones from reduced chondrocyte proliferation and accelerated differentiation. Loss of DNA methylation elevates energy metabolism genes and metabolites, indicating Dnmt1 controls chondrocyte fate and bone length.

Piezoelectric coupling of a single superconducting qubit to two phononic crystal nanoresonators results in an integrated device that is able to control and read out the quantum state of the two mechanical resonators.

The voltage-sensing domain of Ci-VSP regulates the enzymatic activity of its PTEN-like phosphatase domain. New structural and functional data identify a gating loop that controls access to the enzyme's active site and is coupled to voltage sensor movements.

Selene Fernandez-Valverde recounts her challenges in starting a research group in Mexico.

Efficient protocols for comparing quantum states generated on different quantum computing platforms are becoming increasingly important. Zhu et al. demonstrate cross-platform verification using randomized measurements that allow for scaling to larger systems as compared to full quantum state tomography.

For FRB 121102, 1,652 burst events are detected over 47 days, with a peak burst rate of 122 per hour, a bimodal burst rate energy distribution, and no periodicity or quasi-periodicity.

The study analyses data from NASA’s MMS mission to examine electromagnetic fluctuations in the electron diffusion region of Earth’s magnetotail offering insights into the link between reconnection and turbulence. It finds that electromagnetic anomalous viscosity supplies, at times, around 20% of the reconnection electric field.

The growth of aortic aneurysms can be predicted via a dimensionless physiomarker, derived from first principles and calculated from data acquired via 4D flow magnetic resonance imaging, that describes a transition from stable blood flow to unstable aortic fluttering.

Interfaces for epidermal virtual reality technology are demonstrated that can communicate by programmable patterns of localized mechanical vibrations.

Patricia Munroe, Christopher Newton-Cheh, Andrew Morris and colleagues perform association studies in over 340,000 individuals of European ancestry and identify 66 loci, of which 17 are novel, involved in blood pressure regulation. The risk SNPs are enriched for cis-regulatory elements, particularly in vascular endothelial cells.

Upon emerging from their pupal case, insects swiftly deploy their wings from a compact origami-like structure to a fully extended blade. Here, authors use a combination of imaging and mechanical tests to model the kinematics and dynamics of wing deployment in Drosophila.

Single-cell multi-omics technologies have increased dramatically in biomedical research. Lakkis et al. develop a deep learning method to address computational challenges in CITE-seq and single-cell RNA-seq datasets.

The mechanisms responsible for the strongly correlated insulating and superconducting phases in twisted bilayer graphene are still debated. The authors provide a theory for phonon-dominated transport that explains several experimental observations, and contrast it with the Planckian dissipation mechanism.

The C-terminal domain of the largest subunit of RNA polymerase II (CTD) is phosphorylated and recruits regulators of transcription. Here the authors show that phosphorylated CTD, upon specific binding to transcription regulators, forms distinct condensates from wildtype CTD, impact promoter binding and RNA processing.

In tomato roots, the exodermis forms a genetically distinct polar lignin cap (PLC) barrier from the Casparian strip. SlSCZ and SlEXO1 repress PLC deposition in inner layers. The PLC cannot fully compensate for the CS as a mineral ion barrier.

Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.   

A programmable neutral-atom quantum computer based on a two-dimensional array of qubits led to the creation of 2–6-qubit Greenberger–Horne–Zeilinger states and showed the ability to execute quantum phase estimation and optimization algorithms.