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Scientific Reports (17)
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Showing 1–50 of 69 results

Advanced filters: Author: Yanrong Chen Clear advanced filters

A bottom-up septal inhibitory circuit mediates anticipatory control of drinking

Xu et al. reveal that a bottom-up neural circuit from the medial septum to the subfornical organ prevents overhydration in mice by integrating oral and gastrointestinal signals before osmolality changes, demonstrating precise drinking control mechanisms.

Lingyu Xu
Yuhao Sun
Zhong Chen
Research22 Sept 2025
Nature Neuroscience

P: 1-12
A whole-brain male mouse atlas of long-range inputs to histaminergic neurons

Structural and functional understanding of the afferent inputs to histaminergic neurons remains incomplete and lacks systematic characterization. Herein, the authors establish a comprehensive and precise whole-brain atlas of long-range inputs to mouse histaminergic neurons and investigate the representative upstream histaminergic neural circuits in regulating the sleep-wake cycle.

Wenkai Lin
Xinyan Zhu
Zhong Chen
ResearchOpen Access29 Aug 2025
Nature Communications

Volume: 16, P: 1-17
Pathogenesis-adaptive polydopamine nanosystem for sequential therapy of ischemic stroke

Reperfusion is a main strategy for restoring blood supply after ischemic stroke, but it induces neuroinflammation that undergoes dynamic progression, hindering the treatment of ischemic stroke. Here, the authors report a pathogenesis-adaptive nanosystem for sequential and on-demand regulation of reperfusion-induced dynamic neuroinflammation for ischemic stroke therapy.

Di Wu
Jing Zhou
Zhong Chen
ResearchOpen Access06 Nov 2023
Nature Communications

Volume: 14, P: 1-13
Cascaded exciton energy transfer in a monolayer semiconductor lateral heterostructure assisted by surface plasmon polariton

Exciton energy transfer in monolayer transition metal dichalcogenides is limited to short distances. Here, Shi et al. fabricate a planar metal-oxide-semiconductor structure and show that exciton energy transfer can be extended to tens of microns, mediated by an exciton-surface-plasmon-polariton–exciton conversion mechanism.

Jinwei Shi
Meng-Hsien Lin
Shangjr Gwo
ResearchOpen Access26 Jun 2017
Nature Communications

Volume: 8, P: 1-7
Exploration of stationery items unearthed from the Tomb of Murong Zhi of Tuyuhun in the Tang Dynasty

Guoke Chen
Wenting Gu
Yanrong Chen
ResearchOpen Access17 Sept 2025
npj Heritage Science

Volume: 13, P: 1-10
Genome sequencing of ‘Fuji’ apple clonal varieties reveals genetic mechanism of the spur-type morphology

Spur-type of growth is preferred for apple production. Here, the authors employ the trio-based phasing approach to assemble a fully phased Fuji genome and reveal the association of a 167-bp deletion in the promoter region of the MdTCP11 gene with the spur-type varieties.

Yudong Cai
Xiuhua Gao
Dong Zhang
ResearchOpen Access21 Nov 2024
Nature Communications

Volume: 15, P: 1-14
Author Correction: ABHD5 inhibits YAP-induced c-Met overexpression and colon cancer cell stemness via suppressing YAP methylation

Yan Gu
Yanrong Chen
Juanjuan Ou
Amendments and CorrectionsOpen Access04 Apr 2023
Nature Communications

Volume: 14, P: 1
Activated astrocytes attenuate neocortical seizures in rodent models through driving Na⁺-K⁺-ATPase

Neocortical epilepsy is resistant to current treatments. Zhao et al. report that optogenetic stimulation of astrocytes effectively attenuates seizures via driving Na⁺-K⁺-ATPase, indicating a potential treatment strategy for intractable epilepsy.

Junli Zhao
Jinyi Sun
Yi Wang
ResearchOpen Access21 Nov 2022
Nature Communications

Volume: 13, P: 1-15
Influence of dynamic changes of ocular biometric parameters on new-onset myopia in Chinese children: a 4-year cohort study

Zengrui Zhang
Jingyu Mu
Junguo Duan
ResearchOpen Access04 Aug 2025
Scientific Reports

Volume: 15, P: 1-12
Histamine-tuned subicular circuit mediates alert-driven accelerated locomotion in mice

The circuitry mechanism governing alert-driven accelerated locomotion remains unclear. Here, the authors report that a histamine-tuned subicular circuit plays a critical role in alert-driven accelerated locomotion in mice.

Lin Yang
Mengdi Zhang
Zhong Chen
ResearchOpen Access14 Nov 2024
Nature Communications

Volume: 15, P: 1-16
A community effort to optimize sequence-based deep learning models of gene regulation

A benchmarking competition improves tools that predict how regulatory regions control gene expression.

Abdul Muntakim Rafi
Daria Nogina
Carl G. de Boer
ResearchOpen Access11 Oct 2024
Nature Biotechnology

Volume: 43, P: 1373-1383
Significance of baseline and change in neutrophil-to-lymphocyte ratio in predicting prognosis: a retrospective analysis in advanced pancreatic ductal adenocarcinoma

Yang Chen
Huan Yan
GuangHai Dai
ResearchOpen Access09 Apr 2017
Scientific Reports

Volume: 7, P: 1-9
ABHD5 inhibits YAP-induced c-Met overexpression and colon cancer cell stemness via suppressing YAP methylation

This study reveals an unrecognized role of ABHD5 in regulating colon cancer stemness via controlling YAP methylation and nuclear localization, further explaining the molecular mechanism through which ABHD5 functions as a tumour suppressor gene in colon cancer.

Yan Gu
Yanrong Chen
Juanjuan Ou
ResearchOpen Access18 Nov 2021
Nature Communications

Volume: 12, P: 1-15
Temporal dynamics in viral shedding and transmissibility of COVID-19

Presymptomatic transmission of SARS-CoV-2 is estimated to account for a substantial proportion of COVID-19 cases.

Xi He
Eric H. Y. Lau
Gabriel M. Leung
Research15 Apr 2020
Nature Medicine

Volume: 26, P: 672-675
Histamine H₁ receptors in dentate gyrus-projecting cholinergic neurons of the medial septum suppress contextual fear retrieval in mice

Neural mechanism underlying fear memory process is not fully understood. Here, the authors report that histamine H₁ receptor (H₁R) in medial septum cholinergic neurons is critical for contextual fear retrieval, serving as a promising target for related neurological disease.

Li Cheng
Ling Xiao
Zhong Chen
ResearchOpen Access10 Jul 2024
Nature Communications

Volume: 15, P: 1-14
Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney injury via miR-195a-5p-SIRT3 axis

Tubulointerstitial inflammation occurs frequently in acute kidney injury (AKI), and Mφ autophagy is a known contributor to inflammation-related diseases. Here, Yuan et al. show that Mφ autophagy deficiency induces systemic inflammation, impairs mitochondria, and worsens kidney injury in AKI mice.

Yujia Yuan
Longhui Yuan
Yanrong Lu
ResearchOpen Access23 May 2024
Nature Communications

Volume: 15, P: 1-17
Exploring alternatives for detecting microplastics in the human body: questionnaire survey

Yanrong Wang
Yongbin Zhu
Jiangping Li
ResearchOpen Access08 Oct 2024
Scientific Reports

Volume: 14, P: 1-8
Cell transcriptomic atlas of the non-human primate Macaca fascicularis

A large-scale single-cell transcriptomic atlas of the non-human primate Macaca fascicularis encompasses over 1 million cells from 45 adult tissues.

Lei Han
Xiaoyu Wei
Longqi Liu
Research13 Apr 2022
Nature

Volume: 604, P: 723-731
Histamine H₁ receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice

Social impairment and anhedonia are common negative symptoms in patients with schizophrenia. Here, the authors show that the histamine H₁ receptor in cholinergic neurons in the basal forebrain has a critical role in sensorimotor gating, social behaviour, and anhedonia-like behaviour in mice.

Li Cheng
Cenglin Xu
Zhong Chen
ResearchOpen Access18 Feb 2021
Nature Communications

Volume: 12, P: 1-17
All-polymer particulate slurry batteries

Redox flow batteries are promising for large-scale energy storage, but are hindered by cost, stability, and safety issues. Here the authors construct an all-polymer particulate slurry battery to bypass solubility limits and apply insoluble redox-active materials.

Wen Yan
Caixing Wang
Zhong Jin
ResearchOpen Access07 Jun 2019
Nature Communications

Volume: 10, P: 1-11
High-bandwidth perovskite photonic sources on silicon

Tailoring the composition of organic cations enables manipulating the recombination rates of perovskites. Optimized solution-processed perovskite emitters fabricated on silicon exhibit up to 42.6-MHz modulation bandwidth and 50-Mbps data rate.

Aobo Ren
Hao Wang
Wei Zhang
Research20 Jul 2023
Nature Photonics

Volume: 17, P: 798-805
ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield

The mechanisms underlying differential chemotherapeutic response to 5-fluorouracil are not fully known. Here, the authors show that ABDH5 regulates sensitivity to 5-fluorouracil in colorectal cancer by regulating lysosome function.

Juanjuan Ou
Yuan Peng
Houjie Liang
ResearchOpen Access06 Mar 2019
Nature Communications

Volume: 10, P: 1-14
A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain

Extracellular potassium levels in the brain can be correlated to neural activity. A selective potassium sensor, in which cations other than potassium are shielded by a membrane, can measure potassium concentration changes in the brain of freely moving mice undergoing epileptic seizures.

Jianan Liu
Fangyuan Li
Daishun Ling
Research10 Feb 2020
Nature Nanotechnology

Volume: 15, P: 321-330
Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace

Methods to reanalyze scRNA-seq data in a spatial perspective are vital but lacking. Here, the authors develop scSpace, an integrative method that uses ST data as spatial reference to reconstruct the pseudo-space of scRNA-seq data and identify spatially variable cell subpopulations, providing insights into spatial heterogeneity from scRNA-seq data.

Jingyang Qian
Jie Liao
Xiaohui Fan
ResearchOpen Access29 Apr 2023
Nature Communications

Volume: 14, P: 1-18
Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis

By screening 85 deubiquitylation enzymes, Zhang and colleagues identify OTUD3 as an enzyme that upregulates PTEN levels by deubiquitylation and acts as a tumour suppressor in synergy with another PTEN DUB, USP13.

Lin Yuan
Yanrong Lv
Lingqiang Zhang
Research17 Aug 2015
Nature Cell Biology

Volume: 17, P: 1169-1181
Rapid mass production of two-dimensional metal oxides and hydroxides via the molten salts method

2D materials with exotic electronic properties are increasingly important for the development of low-dimensional electronic devices. Here, Huet al. have developed a fast and efficient method to synthesize 2D metal oxides and hydroxides, further enabling 2D electronics.

Zhimi Hu
Xu Xiao
Jun Zhou
ResearchOpen Access30 May 2017
Nature Communications

Volume: 8, P: 1-9
Author Correction: Temporal dynamics in viral shedding and transmissibility of COVID-19

Xi He
Eric H. Y. Lau
Gabriel M. Leung
Amendments and Corrections07 Aug 2020
Nature Medicine

Volume: 26, P: 1491-1493
The method to soften the concretions of ceramics in the “Nanhai I” Shipwreck of China Southern Song Dynasty (1127–1279AD)

Yanrong Wang
Tiequan Zhu
Haotian Chen
ResearchOpen Access01 Feb 2018
Heritage Science

Volume: 6, P: 1-10
Protein–Protein Affinity Determination by Quantitative FRET Quenching

Ling Jiang
Zhehao Xiong
Jiayu Liao
ResearchOpen Access14 Feb 2019
Scientific Reports

Volume: 9, P: 1-8
Problems and Solutions in Click Chemistry Applied to Drug Probes

Weilong Zhong
Bo Sun
Cheng Yang
ResearchOpen Access26 Oct 2016
Scientific Reports

Volume: 6, P: 1-6
Multipole Modes Excitation of uncoupled dark Plasmons Resonators based on Frequency Selective Surface at X-band Frequency Regime

Yu Lan
Yuehang Xu
Yanrong Li
ResearchOpen Access25 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
The Origin of Local Strain in Highly Epitaxial Oxide Thin Films

Chunrui Ma
Ming Liu
Qingyu Zhang
ResearchOpen Access31 Oct 2013
Scientific Reports

Volume: 3, P: 1-5
A donor-DNA-free CRISPR/Cas-based approach to gene knock-up in rice

This study reports a donor DNA-free approach for gene knock-up based on CRISPR. It induced designed promoter swap or replacement for target genes by triggering genomic inversion or duplication so as to elevate gene expression and generate new traits.

Yu Lu
Jiyao Wang
Linjian Jiang
Research15 Nov 2021
Nature Plants

Volume: 7, P: 1445-1452
N-deglycosylation targeting chimera (DGlyTAC): a strategy for immune checkpoint proteins inactivation by specifically removing N-glycan

Li Li
Jiajia Wu
Ping Wang
ResearchOpen Access28 Apr 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-15
Reparation of nano-FeS by ultrasonic precipitation for treatment of acidic chromium-containing wastewater

Mengjia Dai
Junzhen Di
Saiou Fu
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-13
fNIRS experimental study on the impact of AI-synthesized familiar voices on brain neural responses

Weijia Zhang
Jiaju Li
Shaomin Cai
ResearchOpen Access15 May 2025
Scientific Reports

Volume: 15, P: 1-16
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation

Baoxiang Chen
Yuntian Hong
Congqing Jiang
ResearchOpen Access08 Dec 2023
Cell Death & Disease

Volume: 14, P: 1-14
Effect of population, collection year, after-ripening and incubation condition on seed germination of Stipa bungeana

Rui Zhang
J. M. Baskin
Yanrong Wang
ResearchOpen Access24 Oct 2017
Scientific Reports

Volume: 7, P: 1-11
The role of phosphorylation of MLF2 at serine 24 in BCR-ABL leukemogenesis

Juhua Yang
Donglin Cao
Jia Fei
Research12 Dec 2019
Cancer Gene Therapy

Volume: 27, P: 98-107
Cell death dependent on holins LrgAB repressed by a novel ArsR family regulator CdsR

Xin Zhang
Yuhan Chen
Fuping Song
ResearchOpen Access11 Apr 2024
Cell Death Discovery

Volume: 10, P: 1-13
A chain mediation model reveals the association between metacognition and quality of life in hematologic tumor patients

Chunyan Cheng
Meiqiong Zheng
Panpan Cui
ResearchOpen Access08 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Author Correction: Neuroprotection by acetyl-11-keto-β-boswellic acid, in ischemic brain injury involves the Nrf2/HO-1 defense pathway

Yi Ding
MinChun Chen
AiDong Wen
Amendments and CorrectionsOpen Access07 Jul 2022
Scientific Reports

Volume: 12, P: 1-2
COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors

Xi He
Chenshu Liu
Chunliang Lei
ResearchOpen Access16 Dec 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-12
Adsorption behaviors and mechanisms of Cu²⁺, Zn²⁺ and Pb²⁺ by magnetically modified lignite

Junzhen Di
Zhen Ruan
Guoliang Jiang
ResearchOpen Access26 Jan 2022
Scientific Reports

Volume: 12, P: 1-18
NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy

Tengfei Fan
Xiaoning Wang
Zhiyuan Zhang
ResearchOpen Access25 Apr 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-11
Thymidine phosphorylase promotes metastasis and serves as a marker of poor prognosis in hepatocellular carcinoma

Qiang Zhang
Yang Zhang
Cheng Yang
Research22 May 2017
Laboratory Investigation

Volume: 97, P: 903-912
Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation

Chi Zhang
Yue Zhang
Juanjuan Ou
ResearchOpen Access23 Jan 2024
Cell Death Discovery

Volume: 10, P: 1-15
Regulation of blood pressure, oxidative stress and AT1R by high salt diet in mutant human dopamine D5 receptor transgenic mice

Xing Liu
Wenjie Wang
Zhiwei Yang
Research26 Feb 2015
Hypertension Research

Volume: 38, P: 394-399
Correction: Thymidine phosphorylase promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect

Qiang Zhang
Yuan Qin
Cheng Yang
Amendments and CorrectionsOpen Access09 Feb 2022
Cell Death & Disease

Volume: 13, P: 1-3
Correction: Interaction between laminin-5γ2 and integrin β1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins

Bijiao Zhou
Shumin Zong
Yanrong Liu
Amendments and Corrections12 Aug 2022
Oncogene

Volume: 41, P: 4405-4406

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