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Showing 1–50 of 77 results

Advanced filters: Author: Yong Jun Cha Clear advanced filters

Factors associated with shock-refractory prehospital cardiac arrest

Kyung Hun Yoo
Byuk Sung Ko
Hye Jee Joo
ResearchOpen Access18 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
Na+-Ca2+ exchanger modulates Ca2+ content in intracellular Ca2+ stores in rat osteoblasts

Sang Yong Jung
Yong Joo Park
Chang Kook Suh
ResearchOpen Access01 Aug 2007
Experimental & Molecular Medicine

Volume: 39, P: 458-468
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

Maximilian Zenk
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Safety and effectiveness of anticoagulation with non-vitamin K antagonist oral anticoagulants and warfarin in patients on tuberculosis treatment

Hyun-Jung Lee
Hyung-Kwan Kim
Yong-Jin Kim
ResearchOpen Access04 Feb 2023
Scientific Reports

Volume: 13, P: 1-8
Experimental Demonstration of Adaptive Infrared Multispectral Imaging using Plasmonic Filter Array

Woo-Yong Jang
Zahyun Ku
Augustine Urbas
ResearchOpen Access10 Oct 2016
Scientific Reports

Volume: 6, P: 1-9
OsCDPK24 and OsCDPK28 phosphorylate heat shock factor OsHSFA4d to orchestrate abiotic and biotic stress responses in rice

Fang et al. demonstrate that OsHSFA4d enhances thermotolerance by activating HSP101 and promoting CslF6 expression, which suppresses disease resistance. It is phosphorylated by OsCDPK24/28, increasing its DNA binding ability under heat stress. This trade-off mechanism of abiotic/biotic stress may broadly exist in plant kingdom.

Yu Fang
Haicheng Liao
Xuewei Chen
ResearchOpen Access14 Jul 2025
Nature Communications

Volume: 16, P: 1-19
FOXL2 posttranslational modifications mediated by GSK3β determine the growth of granulosa cell tumours

The majority of ovarian granulosa tumours harbour the C134W mutation in FOXL2 but the mechanism of tumorigenesis is largely unknown. Here, Kim et al. show that mutant FOXL2 is hyperphosphorylated by GSK3β, which targets the protein for degradation, and find that GSK3β inhibition represses the growth of ovarian granulosa cells.

Jae-Hong Kim
Yong-Hak Kim
Jeehyeon Bae
Research03 Jan 2014
Nature Communications

Volume: 5, P: 1-13
Assessing antimicrobial resistance connectivity across One Health sectors

Antimicrobial resistance has evolved over decades due to widespread antimicrobial use, with resistance genes now circulating across humans, animals and the environment, creating complex cross-sector connectivity challenges. This Perspective advocates for genomics-based studies of AMR connectivity to enable coordinated global action and investment under the One Health framework.

Liguan Li
Bing Li
Tong Zhang
Reviews29 Sept 2025
Nature Water

P: 1-14
Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly

Current treatments for chronic hepatitis B virus (HBV) infection are not curative. Here, the authors show that an antifungal drug, ciclopirox, inhibits HBV capsid assembly and synergizes with nucleoside/nucleotide analogs to prevent HBV replication in cells and in a humanized liver mouse model.

Jung-Ah Kang
Songwon Kim
Sung-Gyoo Park
ResearchOpen Access16 May 2019
Nature Communications

Volume: 10, P: 1-14
Understanding the effect of spatially separated Cu and acid sites in zeolite catalysts on oxidation of methane

Methane is a potent greenhouse gas, and its removal is critical. Here, the authors demonstrate that spatially separated Cu and acid sites in Cu/zeolites influence product distribution and efficiency for methane oxidation.

Peipei Xiao
Yong Wang
Toshiyuki Yokoi
ResearchOpen Access28 Mar 2024
Nature Communications

Volume: 15, P: 1-10
Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor

Li Huang
Jonathan C Ramirez
Sharon DeMorrow
Research04 Apr 2011
Laboratory Investigation

Volume: 91, P: 1007-1017
Dual-functionality of Nocardiopsis alba B57 in biocontrol and plant growth: a metabolomic approach to agricultural sustainability

Osama Abdalla Abdelshafy Mohamad
Yong-Hong Liu
Wen-Jun Li
ResearchOpen Access18 Aug 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-18
Characteristics of Atrial Fibrillation Patients Suffering Esophageal Injury Caused by Ablation for Atrial Fibrillation

Pei Zhang
Yue-Yue Zhang
Chen-Yang Jiang
ResearchOpen Access17 Feb 2020
Scientific Reports

Volume: 10, P: 1-9
Mechanosensory neurons control sweet sensing in Drosophila

How different sensory modalities interact to control feeding is poorly understood. Here, authors show that in Drosophila, activation of labellar mechanosensory neurons causes inhibition of sweet-sensing gustatory receptor neurons, as a result, Drosophilaprefer soft food at the expense of sweetness.

Yong Taek Jeong
Soo Min Oh
Seok Jun Moon
ResearchOpen Access19 Sept 2016
Nature Communications

Volume: 7, P: 1-9
TGF-β1 Upregulates the Expression of Triggering Receptor Expressed on Myeloid Cells 1 in Murine Lungs

Li Peng
Yong Zhou
Cha-Xiang Guan
ResearchOpen Access07 Jan 2016
Scientific Reports

Volume: 6, P: 1-9
Efficient gene delivery in differentiated human embryonic stem cells

Jae-Hwan Kim
Hyun-Jin Do
Hyung-Min Chung
ResearchOpen Access01 Feb 2005
Experimental & Molecular Medicine

Volume: 37, P: 36-44
Viscoelastic and antimicrobial dental care bioplastic with recyclable life cycle

Medical plastic-appliance-based healthcare services, especially in dentistry, generate large amounts of plastic waste. Here, the authors address this issue by developing a medical-grade and sustainable bioplastic that is viscoelastic enough to align the tooth positions, resists microbial contamination, and exhibits recyclable life cycles.

Woojin Choi
Utkarsh Mangal
Jinkee Hong
ResearchOpen Access24 Oct 2024
Nature Communications

Volume: 15, P: 1-14
Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress

Cancer cell survival under metabolic stress is a critical step for metastasis. Here, the authors show that under glucose deprivation, Snail, a key regulator of the metastatic process, promotes survival by diverting glucose to the pentose phosphate pathway through repression of phosphofructokinase PFKP.

Nam Hee Kim
Yong Hoon Cha
Hyun Sil Kim
ResearchOpen Access08 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

A meta-analysis of genome-wide association studies of type 2 diabetes (T2D) identifies more than 600 T2D-associated loci; integrating physiological trait and single-cell chromatin accessibility data at these loci sheds light on heterogeneity within the T2D phenotype.

Ken Suzuki
Konstantinos Hatzikotoulas
Eleftheria Zeggini
ResearchOpen Access19 Feb 2024
Nature

Volume: 627, P: 347-357
Sex-related differences in presentation, treatment, and outcomes of Asian patients with atrial fibrillation: a report from the prospective APHRS-AF Registry

Tommaso Bucci
Alena Shantsila
Sheng-Hsiung Chang
ResearchOpen Access26 Oct 2023
Scientific Reports

Volume: 13, P: 1-11
DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling

Osteoblasts and endothelial cells have important roles in bone regeneration. Kim and colleagues identify the protein DJ-1 as an angiogenic and osteogenic signalling molecule involved in the cross-talk between these cells and show that DJ-1 promotes bone regeneration and fracture healing in mice.

Jung-Min Kim
Hong-In Shin
Pann-Ghill Suh
Research18 Dec 2012
Nature Communications

Volume: 3, P: 1-11
Mitochondrial DNA mosaicism in normal human somatic cells

Analysis of 2,096 single-cell clones from three tissues of 31 healthy donors characterizes mitochondrial DNA mosaicism and highlights the following two origins of mtDNA variants: heteroplasmy in the fertilized egg and postzygotic mutations.

Jisong An
Chang Hyun Nam
Young Seok Ju
ResearchOpen Access22 Jul 2024
Nature Genetics

Volume: 56, P: 1665-1677
Erratum: TI - Efficient gene delivery in differentiated human embryonic stem cells

Jae-Hwan Kim
Hyun-Jin Do
Hyung-Min Chung
Amendments and CorrectionsOpen Access01 Oct 2006
Experimental & Molecular Medicine

Volume: 38, P: 589
Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protein kinases

Tian-hua Zhang
Jian-feng Liu
Tatsuo Yamakawa
Research01 Mar 2007
Acta Pharmacologica Sinica

Volume: 28, P: 439-445
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer

Jia-Hao Tao
Jun Zhang
Cha-Xiang Guan
Research05 Sept 2025
Cancer Gene Therapy

P: 1-17
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Genome-wide association and fine-mapping analyses in ancestrally diverse populations implicate candidate causal genes and mechanisms underlying type 2 diabetes. Trans-ancestry genetic risk scores enhance transferability across populations.

Anubha Mahajan
Cassandra N. Spracklen
Andrew P. Morris
Research12 May 2022
Nature Genetics

Volume: 54, P: 560-572
Extensive genetic diversity of Rickettsiales bacteria in multiple mosquito species

Wen-Ping Guo
Jun-Hua Tian
Yong-Zhen Zhang
ResearchOpen Access09 Dec 2016
Scientific Reports

Volume: 6, P: 1-11
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner

Hippo and Wnt pathways are important for cancer development, and they can cross talk; however, the mechanisms behind this connection are unknown. Here the authors show that DVL (a scaffold protein in the Wnt pathway) regulates the shuttling of YAP (a key component of the Hippo pathway) between cytoplasm and nucleus in specific tumor suppressor contexts.

Yoonmi Lee
Nam Hee Kim
Jong In Yook
ResearchOpen Access12 Jun 2018
Nature Communications

Volume: 9, P: 1-16
Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

Kim and colleagues and Kwon and colleagues reveal that amino-terminal arginylation of BiP promotes its targeting to autophagy adaptor p62 and subsequent lysosomal degradation of BiP, p62 and associated cargo.

Hyunjoo Cha-Molstad
Ki Sa Sung
Yong Tae Kwon
Research15 Jun 2015
Nature Cell Biology

Volume: 17, P: 917-929
Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter

Seung-Soon Im
Jae-Woo Kim
Yong-Ho Ahn
ResearchOpen Access01 Apr 2005
Experimental & Molecular Medicine

Volume: 37, P: 101-110
Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression

Mobilization of hematopoietic stem and progenitor cells (HSPCs) into the circulation is essential for maintaining homeostasis. Here, the authors show that Phc2 in bone marrow stromal cells represses the cell adhesion molecule Vcam1 and facilitates mobilization of HSPCs through regulation of epigenetic marks.

Joonbeom Bae
Sang-Pil Choi
Taehoon Chun
ResearchOpen Access02 Aug 2019
Nature Communications

Volume: 10, P: 1-14
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

Soluble misfolded proteins that fail to be degraded by the ubiquitin proteasome system (UPS) are redirected to autophagy via specific adaptors, such as p62. Here the authors show that p62 recognises N-degrons in these proteins, acting as a N-recognin from the proteolytic N-end rule pathway, and targets these cargos to autophagosomal degradation.

Hyunjoo Cha-Molstad
Ji Eun Yu
Bo Yeon Kim
ResearchOpen Access24 Jul 2017
Nature Communications

Volume: 8, P: 1-17
Discovering molecular signatures in kidney transplant biopsies with borderline changes and isolated V-lesions: single-cell RNA-sequencing analysis of human blood and tissue Spatial transcriptomics

Jeongin Song
Minji Kang
Yong Chul Kim
ResearchOpen Access03 Jul 2025
Scientific Reports

Volume: 15, P: 1-18
N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer

Rebecca Yun
Eunji Hong
Jin Muk Kang
ResearchOpen Access23 Aug 2023
Cell Death & Disease

Volume: 14, P: 1-12
Comparison of definitions of bronchopulmonary dysplasia to reflect the long-term outcomes of extremely preterm infants

Ga Won Jeon
Minkyung Oh
Yun Sil Chang
ResearchOpen Access27 Oct 2022
Scientific Reports

Volume: 12, P: 1-10
Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery

Jiho Jang
Jeong-Eun Yoo
Dong-Wook Kim
ResearchOpen Access19 Dec 2011
Experimental & Molecular Medicine

Volume: 44, P: 202-213
Deep learning-based automatic segmentation of cerebral infarcts on diffusion MRI

Wi-Sun Ryu
Dawid Schellingerhout
Dong-Eog Kim
ResearchOpen Access16 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Impact of genetic variants on major bleeding after percutaneous coronary intervention based on a prospective multicenter registry

Jung-Joon Cha
Hyung Joon Joo
Do-Sun Lim
ResearchOpen Access19 Jan 2021
Scientific Reports

Volume: 11, P: 1-8
Comparison between norepinephrine plus epinephrine and norepinephrine plus vasopressin after return of spontaneous circulation in patients with out-of-hospital cardiac arrest

Sejoong Ahn
Bo-Yeong Jin
Ji Hoon Kim
ResearchOpen Access18 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Anatomy of the external branch of the superior laryngeal nerve in Asian population

Yong Hoon Cha
Seo-Young Moon
Hun-Mu Yang
ResearchOpen Access02 Nov 2017
Scientific Reports

Volume: 7, P: 1-9
Simultaneous Detection of EGFR and VEGF in Colorectal Cancer using Fluorescence-Raman Endoscopy

Yong-il Kim
Sinyoung Jeong
Dong Soo Lee
ResearchOpen Access21 Apr 2017
Scientific Reports

Volume: 7, P: 1-11
Spirulina maxima extract prevents activation of the NLRP3 inflammasome by inhibiting ERK signaling

Sungwoo Chei
Hyun-Ji Oh
Boo-Yong Lee
ResearchOpen Access07 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
Latent class analysis of psychotic-affective disorders with data-driven plasma proteomics

Sang Jin Rhee
Dongyoon Shin
Yong Min Ahn
ResearchOpen Access06 Feb 2023
Translational Psychiatry

Volume: 13, P: 1-8
Effect of moderate-intensity statin with ezetimibe combination vs. high-intensity statin therapy according to sex in patients with atherosclerosis

Byung Gyu Kim
Seung-Jun Lee
Jung-Sun Kim
ResearchOpen Access17 Nov 2023
Scientific Reports

Volume: 13, P: 1-10
Impact of non-traditional lipid profiles on 1-year vascular outcomes in ischemic stroke patients with prior statin therapy and LDL-C < 100 mg/dL

Hyunsoo Kim
Joon-Tae Kim
Hee-Joon Bae
ResearchOpen Access01 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Fecal microbial transplantation and a high fiber diet attenuates emphysema development by suppressing inflammation and apoptosis

Yoon Ok Jang
Se Hee Lee
Sei Won Lee
ResearchOpen Access17 Jul 2020
Experimental & Molecular Medicine

Volume: 52, P: 1128-1139
Discovery of highly immunogenic spleen-resident FCGR3⁺CD103⁺ cDC1s differentiated by IL-33-primed ST2⁺ basophils

Myeong-Ho Kang
JungHyub Hong
Yong-Soo Bae
ResearchOpen Access29 May 2023
Cellular & Molecular Immunology

Volume: 20, P: 820-834
Augmented risk of ischemic stroke in hypertrophic cardiomyopathy patients without documented atrial fibrillation

You-Jung Choi
Bongseong Kim
Hyung-Kwan Kim
ResearchOpen Access22 Sept 2022
Scientific Reports

Volume: 12, P: 1-8
Inter hospital external validation of interpretable machine learning based triage score for the emergency department using common data model

Jae Yong Yu
Doyeop Kim
Won Chul Cha
ResearchOpen Access20 Mar 2024
Scientific Reports

Volume: 14, P: 1-9

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