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Showing 1–18 of 18 results

Advanced filters: Author: Zhengfeng Sun Clear advanced filters

CFAP100 couples microtubule glutamylation to spindle pole integrity in keratinocytes to promote epidermal development

Sun et al. identify CFAP100 as a vital player in the regulation of epidermal development and function. Mechanistically, CFAP100 recruits the microtubule glutamylase TTLL13 to ensure spindle pole integrity for proper division of keratinocytes.

Shuang Sun
Zhaoying Wang
Jun Zhou
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
A single-dose circular RNA vaccine prevents Zika virus infection without enhancing dengue severity in mice

Neutralizing antibodies binding the domain III of Zika virus envelope protein (EDIII) are desired in vaccine development. Here, the authors express dimeric EDIII fused to human IgG1 Fc fragment from circular RNA, and show immunogenicity and protection in mice.

Xinglong Liu
Zhengfeng Li
Liqiang Feng
ResearchOpen Access16 Oct 2024
Nature Communications

Volume: 15, P: 1-19
Establishment and Characterization of a Cell Based Artificial Antigen-Presenting Cell for Expansion and Activation of CD8⁺ T Cells Ex Vivo

Weijuan Gong
Mingchun Ji
Xingyuan Pan
Research01 Feb 2008
Cellular & Molecular Immunology

Volume: 5, P: 47-53
Prolonged hypotensive effect of human tissue kallikrein gene delivery and recombinant enzyme administration in spontaneous hypertension rats

Huaichang Sun
Lei Zhang
Zhengfeng Xue
ResearchOpen Access01 Feb 2004
Experimental & Molecular Medicine

Volume: 36, P: 23-27
Maternal ELL3 loss-of-function leads to oocyte aneuploidy and early miscarriage

The authors show that ELL3 maintains chromosomal ploidy by promoting spindle assembly and driving chromosome movement in oocytes. Deficiency of ELL3 results in oocyte aneuploidy and may lead to early miscarriage.

Shiqi Zhu
Peng Xie
Chengqi Lin
Research16 Jan 2025
Nature Structural & Molecular Biology

Volume: 32, P: 381-392
KKK879-881 motif is an ER-retention signal in GluN2A-NMDA receptor

Qing-Qing Li
Jiang Chen
Yun Stone Shi
Research29 Nov 2022
Molecular Psychiatry

Volume: 27, P: 3115
High-performance fibre battery with polymer gel electrolyte

A fibre lithium-ion battery that can potentially be woven into textiles shows enhanced battery performance and safety compared with liquid electrolytes.

Chenhao Lu
Haibo Jiang
Huisheng Peng
Research24 Apr 2024
Nature

Volume: 629, P: 86-91
Using Relaxation Time to characterize biological effects of different mutagens

Xinglin Li
Shuguang Sun
Zhengfeng Sun
ResearchOpen Access18 Aug 2020
Scientific Reports

Volume: 10, P: 1-10
Visualizing influenza virus infection in living mice

Mouse models of influenza infection that permit monitoring of infection in living animals are scarce. Here Pan et al. describe an engineered influenza virus expressing luciferase, which enables real-time in vivovisualization of viral infection and assessment of antiviral drugs.

Weiqi Pan
Zhenyuan Dong
Ling Chen
ResearchOpen Access11 Sept 2013
Nature Communications

Volume: 4, P: 1-8
Contributions of rational soil tillage to compaction stress in main peanut producing areas of China

Pu Shen
Zhengfeng Wu
Xinhua He
ResearchOpen Access09 Dec 2016
Scientific Reports

Volume: 6, P: 1-9
Epidemiological characteristics of traumatic cervical spinal cord injury in Chongqing, China, from 2009 to 2018

Dawei Sun
Zhengfeng Zhang
Research04 Aug 2021
Spinal Cord Series and Cases

Volume: 7, P: 1-5
Beyond a single pole: exploring the nuanced coexistence of scientific elitism and populism in China

Shuo Wang
Tuo Wang
Zhengfeng Li
ResearchOpen Access10 Mar 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-13
Paraquat is an agonist of STIM1 and increases intracellular calcium levels

The herbicide paraquat is an agonist of Stromal Interaction Molecule 1 (STIM1), leading to extracellular calcium entry observed in epithelial-mesenchymal transition in alveolar cells during pulmonary fibrosis.

Wenyu Yang
Rui Tian
Ruilan Wang
ResearchOpen Access30 Oct 2022
Communications Biology

Volume: 5, P: 1-11
Correction of a homoplasmic mitochondrial tRNA mutation in patient-derived iPSCs via a mitochondrial base editor

A proof-of-concept study applying a screened RNA-free DddA-derived cytosine base editor (DdCBE) pair to correct the homoplasmic m.A4300G mutation in induced pluripotent stem cells demonstrates the potential of DdCBE-based therapy for treating primary mitochondrial defects.

Xiaoxu Chen
Mingyue Chen
Bin Shen
ResearchOpen Access03 Nov 2023
Communications Biology

Volume: 6, P: 1-11
Enhancing GluN2A-type NMDA receptors impairs long-term synaptic plasticity and learning and memory

Qing-Qing Li
Jiang Chen
Yun Stone Shi
Research28 Apr 2022
Molecular Psychiatry

Volume: 27, P: 3468-3478
DdCBE-mediated mitochondrial base editing in human 3PN embryos

Xiaoxu Chen
Dong Liang
Zhengfeng Xu
CorrespondenceOpen Access01 Feb 2022
Cell Discovery

Volume: 8, P: 1-4
Noninvasive prenatal diagnosis of 21-Hydroxylase deficiency using target capture sequencing of maternal plasma DNA

Dingyuan Ma
Yuan Yuan
Zhengfeng Xu
ResearchOpen Access07 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Low-pass whole-genome sequencing in clinical cytogenetics: a validated approach

Zirui Dong
Jun Zhang
Zhengfeng Xu
Research28 Jan 2016
Genetics in Medicine

Volume: 18, P: 940-948