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Autonomic dysregulation in IBS

Nature Reviews Gastroenterology & Hepatology volume 10, pages 569–571 (2013)Cite this article

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Cheng et al. recently reported that patients with IBS have impaired cardiac sympathetic and vagal response to colonic stimulation owing to the procedure of flexible sigmoidoscopy. The importance of this blunted response of the autonomic nervous system in patients with IBS was discussed alongside the basis of visceral perception.

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Figure 1: Interoception pathway and cardiac efferent activation.

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Acknowledgements

Research by S. Fukudo is supported by Grant-in-Aid for Scientific Research from the Ministry of Education, Science, and Culture of Japan, Grant-in-Aid for Scientific Research from the Ministry of Health, Welfare, and Labour of Japan.

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  1. Department of Behavioural Medicine, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan

    Shin Fukudo

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  1. Shin Fukudo
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Correspondence to Shin Fukudo.

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The author declares no competing financial interests.

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Fukudo, S. Autonomic dysregulation in IBS. Nat Rev Gastroenterol Hepatol 10, 569–571 (2013). https://doi.org/10.1038/nrgastro.2013.166

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