Table 3 The association of BMI-TTR with diabetes incidence by subgroups.

From: Long-term time in target range for body mass index (BMI) and diabetes incidence: insights from CHARLS

Variable

Adjusted HRa (95% Cl)

P value

Adjusted HRb (95% Cl)

P value

Adjusted HRa (95% Cl)

P value

Adjusted HRb (95% Cl)

P value

Male (n = 3143)

Age < 60 (n = 3727)

TTR1

 TTR2

0.981 (0.663–1.451)

0.924

1.089 (0.725–1.636)

0.681

0.624 (0.434–0.897)

0.011

0.722 (0.495–1.054)

0.091

 TTR3

0.753 (0.494–1.147)

0.186

0.853 (0.549–1.327)

0.481

0.494 (0.320–0.762)

0.001

0.601 (0.381–0.949)

0.029

 TTR4

0.580 (0.411–0.818)

0.002

0.675 (0.461–0.988)

0.043

0.457 (0.329–0.634)

<0.001

0.570 (0.396–0.822)

0.003

 BMI of wave 1

  

1.036 (1.000–1.074)

0.050

  

1.043 (1.013–1.074)

0.004

 

Female (n=3519)

Age ≥ 60 (n=2935)

TTR1

 TTR2

0.646 (0.461–0.903)

0.011

0.719 (0.509–1.016)

0.061

0.953 (0.667–1.363)

0.792

1.041 (0.720–1.506)

0.830

 TTR3

0.567 (0.387–0.831)

0.004

0.660 (0.443–0.983)

0.041

0.808 (0.554–1.176)

0.265

0.902 (0.610–1.335)

0.607

 TTR4

0.601 (0.449–0.803)

<0.001

0.707 (0.516–0.970)

0.032

0.725 (0.533–0.985)

0.040

0.822 (0.589–1.146)

0.247

 BMI of wave 1

  

1.033 (1.010–1.057)

0.005

  

1.031 (1.002–1.060)

0.035

 P for interaction

0.225

0.285

0.403

0.425

  1. TTR time in target range, DM diabetes mellitus, BMI body mass index, HR hazard ratio, CI confidence interval, SBP systolic blood pressure, HR heart rate, HDL high-density cholesterol, HbA1c glycated hemoglobin A1c, hsCRP high sensitivity C-reactive protein, eGFR estimated glomerular filtration rate.
  2. aAdjusted For age, sex, hypertension, smoking, SBP, HR, hyperlipidemia, physical exercise, marital status, education, HDL-C, hsCRP, HbA1c, eGFR.
  3. bAdjusted For age, sex, hypertension, smoking, SBP, HR, hyperlipidemia, physical exercise, marital status, education, HDL-C, hsCRP, HbA1c, eGFR, and BMI of wave 1.
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