Table 5 OR (95% CI) for folate levels and GDM prevalence (n = 11,563).

From: Association between assisted reproductive technology and gestational diabetes mellitus: the role of serum folate and triglycerides

 

Folate levels (pmol/L)

P trend

Per-SD increase in folate levels

Q1 (Bottom) ( < 13.80)

Q2 (13.80–18.85)

Q3 (18.86–26.78)

Q4 (26.79–41.67)

Q5 (Top) ( > 41.67)

GDM (%)

112 (4.9%)

151 (6.5%)

199 (8.6%)

212 (9.2%)

295 (12.7%)

< 0.001

 

Unadjusted

1

1.37 (1.06, 1.76)

1.85 (1.45, 2.34)

1.97 (1.56, 2.50)

2.86 (2.28, 3.58)

< 0.001

1.38 (1.30, 1.47)

Model Ⅰ

1

1.35 (1.04, 1.73)

1.83 (1.44, 2.33)

1.94 (1.53, 2.47)

2.78 (2.20, 3.50)

< 0.001

1.37 (1.28, 1.46)

Model Ⅱ

1

1.30 (1.00, 1.69)

1.68 (1.31, 2.17)

1.69 (1.31, 2.18)

2.21 (1.71, 2.85)

< 0.001

1.26 (1.17, 1.35)

  1. Model Ⅰ adjusted for maternal age, prenatal BMI, parity, BP, fetal sex, and ART.
  2. Model Ⅱ adjusted for the variables in Model Ⅰ and the laboratory findings (vitamin B12, tHcy, ALT, AST, urea nitrogen, creatinine, total cholesterol, LDL-C, HDL-C, and triglycerides).
  3. OR Odds ratio, CI Confidence interval, GDM Gestational diabetes mellitus, Q Quintile, SD Standard deviation, BMI Body mass index, BP blood pressure, ART Assisted reproductive technology, tHcy Total homocysteine, ALT Alanine aminotransferase, AST Aspartate aminotransferas, LDL-C Low density lipoprotein cholesterol, HDL-C High density lipoprotein cholesterol.
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