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The evolving landscape of BPH surgical treatments: considering semen parameters in clinical decision-making

Prostate Cancer and Prostatic Diseases (2025)Cite this article

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Traditionally, the primary objective of surgical interventions for BPH has been alleviating lower urinary tract symptoms. However, in recent years, there has been an increasing emphasis on the preservation of sexual function, particularly ejaculatory function. This shift underscores a change in patient priorities, as sexual health and fertility have become critical considerations, especially among younger patients.

In response to these concerns, surgical techniques have been refined to reduce the risk of postoperative sexual dysfunction, with particular attention to the preservation of ejaculatory function [1,2,3,4,5,6]. While these advancements represent substantial progress, their effects on semen quality—a key factor in fertility assessment—remain unexplored.

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Authors and Affiliations

  1. Houston Methodist Department of Urology, Houston, TX, USA

    Miguel Valdivia y Alvarado, Kajal Khodamoradi, Akhil Muthigi & Ricardo R. Gonzalez

  2. Ross University School of Medicine, Two Mile Hill St. Michael, Barbados

    Obinna Obuekwe

  3. The Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA

    Gal Saffati

Authors
  1. Miguel Valdivia y Alvarado
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  2. Obinna Obuekwe
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  3. Gal Saffati
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  4. Kajal Khodamoradi
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  5. Akhil Muthigi
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  6. Ricardo R. Gonzalez
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Contributions

MVA: wrote the original draft of the manuscript. OO: analyzed the qualitative data. GS: analyzed the qualitative data. AM: edited and provided critical feedback on the manuscript. KK: edited and provided critical feedback on the manuscript. RRG: conceived and conceptualized the hypothesis.

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Correspondence to Kajal Khodamoradi.

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Valdivia y Alvarado, M., Obuekwe, O., Saffati, G. et al. The evolving landscape of BPH surgical treatments: considering semen parameters in clinical decision-making. Prostate Cancer Prostatic Dis (2025). https://doi.org/10.1038/s41391-025-00939-y

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