Fig. 2: Genomic and transcriptomic correlation. | Prostate Cancer and Prostatic Diseases

Fig. 2: Genomic and transcriptomic correlation.

From: HLA class I expression shapes the tumor immune microenvironment and influences prognosis in prostate cancer

Fig. 2

Bar graphs showing percentages of pathogenic alterations in AR-related genes A, tumor suppressors B, and HRR-pathway genes C. Bar graphs showing percentages of pathogenic alteration of FOXA1 D and TP53 E in TCGA and SU2C cohorts. Color key for figure A–E is presented next to the figure E. Bubble plots showing differential gene expression of CTLA4 and CD274 (PD-L1) in the Caris cohort, compared to the TCGA and SU2C cohorts F. Bubble plots showing gene set enrichment analysis (GSEA) of cancer-related hallmark gene sets relative to HLA-high groups G.

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