Table 1 Baseline patient characteristics and biopsy outcomes for all patients with PIRADS 3-5 lesions by race.

From: Evaluating PI-RADS lesions and clinically significant prostate cancer in Black and Asian men: a PREVENT randomized clinical trial secondary analysis

 

Asian

Black

White

Overall

p-value

 

(n = 36)

(n = 88)

(n = 414)

(n = 665)

Age, median (IQR)

67 (61–70)

62 (58.5-68)d

66.5 (61-71.5)

66 (61–71)

0.001

Biopsy approach, n (%)

    

0.6

 Transrectal

19 (53)

44 (50)

192 (46)

320 (48)

 

 Transperineal

17 (47)

44 (50)

222 (54)

345 (52)

 

Family History of Prostate Cancer

 Yes, n(%)

3 (8)

11 (13)

92 (22)

115 (17)

0.004

PSAa, median (IQR)

5.88 (4.53-8.38)

6.50 (5.00-9.75)d

5.53 (4.33-7.47)

5.79 (4.48-8.00)

0.02

PSADb, median (IQR)

0.13 (0.09-0.24)

0.17 (0.11-0.31)d

0.13 (0.09-0.20)

0.14 (0.09-0.21)

0.01

PI-RADSc, n (%)

    

0.3

 3

7 (19)

20 (23)

100 (24)

153 (23)

 

 4

16 (44)

50 (57)

196 (47)

319 (48)

 

 5

13 (36)

18 (20)

118 (29)

193 (29)

 

Highest Grade Group, n (%)

    

0.11

 Benign

14 (39)

14 (16)

117 (28)

177 (27)

 

 GG1

3 (8)

15 (17)

74 (18)

102 (15)

 

 GG2

8 (22)

30 (34)

121 (29)

208 (31)

 

 GG3

5 (14)

14 (16)

47 (11)

81 (12)

 

 GG4

2 (6)

5 (6)

20 (5)

34 (5)

 

 GG5

4 (11)

10 (11)

35 (9)

63 (9)

 
  1. aProstate-specific antigen.
  2. bProstate-specific antigen density.
  3. cProstate Imaging Reporting and Data System.
  4. dAll are p < 0.01 when compared to White cohort.