Table 1 Actual (expected) offspring numbers from intercrossing Casp8+/1xDA Cflar+/- mice.
Genetic Background | Age | Casp8+/+ Cflar+/+ | Casp8+/1xDA Cflar+/- | Casp81xDA/1xDA Cflar-/- |
|---|---|---|---|---|
Mlkl-/- | E17.5–E18.5 | 12 (9.25) | 15 (18.5) | 10 (9.25) |
Mlkl-/- | P5–P7 | 35 (25.5) | 67 (51) | 0 (25.5) |
Mlkl-/- Casp1-/- | P5–P7 | 23 (18.25) | 50 (36.5) | 0 (18.25) |
Mlkl-/- Casp1-/- Ifnar1-/- | P5–P7 | 14 (12.25) | 35 (24.5) | 0 (12.25) |
Mlkl-/- Fadd-/- | P5–P7 | 7 (8.75) | 20 (17.5) | 8 (8.75) |
Mlkl-/- Fadd-/- Casp1-/- | P5–P7 | 4 (5.5) | 11 (11) | 7 (5.5) |
Mlkl-/- Fadd+/- Casp1-/- | P5–P7 | 15 (15.25) | 43 (30.5) | 3 (15.25) |
