Fig. 4: MEIS1 promotes the expression of p53 protein but not its mRNA. | Cell Death & Differentiation

Fig. 4: MEIS1 promotes the expression of p53 protein but not its mRNA.

From: Ubiquitination of MEIS1 by MDM2 serves as a switch for p53 stabilization and DNA damage response activation

Fig. 4: MEIS1 promotes the expression of p53 protein but not its mRNA.

A The mRNA expressions of P53, CDKN1A and BAX were analyzed by qPCR in cells with MEIS1 overexpression or knockdown. B The protein levels of p53, p21 and BAX were detected by western blot in cells with MEIS1 overexpression or knockdown. The ubiquitination level of p53 was measured by IP/IB assays in cells with MEIS1 overexpression (C) or knockdown (D).

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