Table 2 Baseline values of haematological parameters and vitamin B12/folate (mean [SD])
Author | Intervention group | Control group | |
|---|---|---|---|
Studies on B12 | |||
Dangour [28] | Haemoglobin (g/dL) | 14.0 (1.1) | 13.8 (1.2) |
Haematocrit (fraction) | 41 (3) | 41 (3) | |
Anaemic individuals (n) | 3 of 80 | 10 of 75 | |
Vitamin B12 (pmol/L) | 232 [52] | 237 [60] | |
B12 deficiency (n) | 3 of 80 | 4 of 75 | |
Favrat [29] | Haematocrit (fraction) | 40.4 (3.9) | 39.8 (4.6) |
Anaemic individuals (n) | 10 of 23 | 7 of 22 | |
Vitamin B12 (pmol/L) | 167 (23) | 155 (20) | |
B12 deficiency (n) | 8 of 23 | 12 of 22 | |
Hvas [30] | Haemoglobin (g/dL) | 13.1 (1.4) | 13.5 (1.2) |
Anaemic individuals (n) | 16 of 67 | 12 of 70 | |
Vitamin B12 (pmol/L) | 303 (159) | 277 [92] | |
B12 deficiency (n) | 1 of 67 | 1 of 70 | |
Haemoglobin (g/dL) | 12.4 (1.4) | 13.2 (1.3) | |
Anaemic individuals (n) | 6 of 12 | 4 of 14 | |
Vitamin B12 (pmol/L) | 135 (27) | 143 (21) | |
B12 deficiency (n) | 9 of 12 | 7 of 14 | |
Haemoglobin (g/dL) | 13.2 (1.7) | 13.2 (1.3) | |
Anaemic individuals (n) | 4 of 14 | 4 of 14 | |
Vitamin B12 (pmol/L) | 153 [39] | 143 (21) | |
B12 deficiency (n) | 10 of 14 | 7 of 14 | |
Studies on folic acid | |||
Durga [32] | Haemoglobin (g/dL) | 14.2 (1.1) | 14.3 (1.1) |
Haematocrit (fraction) | 44 (4) | 44 (4) | |
Anaemic individuals (n) | 22 of 395 | 21 of 407 | |
Folate (nmol/l) | 12.4 (4.3) | 12.6 (4.6) | |
Folate deficiency (n) | 24 of 395 | 30 of 407 | |
Pathansali [33] | Haemoglobin (g/dL) | 13.2 (0.9) | 13.0 (0.9) |
Haematocrit (fraction) | 40 (2) | 40 (2) | |
Anaemic individuals (n) | 3 of 12 | 2 of 12 | |
Folate (nmol/l) | 13.8 (5.0) | 15.0 (6.0) | |
Folate deficiency (n) | 9 of 12 | 7 of 12 | |
Ntaios [34] | Haemoglobin (g/dL) | 13.9 (0.7) | 14.2 (1.2) |
Haematocrit (fraction) | 42 (2) | 43 (4) | |
Anaemic individuals (n) | 4 of 53 | 2 of 50 | |
Folate (nmol/l) | 19.9 (8.7) | 18.2 (6.1) | |
Folate deficiency (n) | 0 of 53 | 0 of 50 | |