Abstract
Recent studies showed that transgender (TGN) adolescents are more at risk of negative sexual outcomes than their peers. However, little is known about the psychopathological and sociodemographic correlates of sexual-related experiences in TGN adolescents. This cross-sectional study aimed at overcoming this limitation describing this association in a sample of 18 transgirls and 32 transboys recruited at the Gender Clinic of the University of Florence between 2015 and 2020. Clinical, sociodemographic, and sexual-related features were collected through a face-to-face interview and anamnestic forms. Self-report questionnaires were administered to evaluate gender dysphoria (Gender Identity/Gender Dysphoria Questionnaire for Adolescents and Adults), emotional and behavioral problems (Youth Self Report), and body uneasiness (Body Uneasiness Test). The percentage of subjects reporting to have had at least one romantic relationship in life was 62.5% among transboys and 16.7% in transgirls (ORsex = 8.65, p < 0.01), whereas 28.1% of transboys and 5.6% of transgirls were sexually active (ORsex = 6.63, p > 0.05). A worse psychological functioning and risk-taking behaviors were associated with being sexually active (p < 0.05). These results underline the deep interconnection between psychological vulnerability and sexual-related features in TGN adolescents, confirming the importance of developing gender inclusive sex education programs to prevent negative sexual outcomes in this population.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others
References
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5®). American Psychiatric Pub; 2013.
Richards C, Bouman WP, Seal L, Barker MJ, Nieder TO, Tsjoen G. Non-binary or genderqueer genders. Int Rev Psychiatry. 2016;28:95–102.
Reed GM, Drescher J, Krueger RB, Atalla E, Cochran SD, First MB, et al. Disorders related to sexuality and gender identity in the ICD-11: revising the ICD-10 classification based on current scientific evidence, best clinical practices, and human rights considerations. World Psychiatry. 2016;15:205–21.
Haley SG, Tordoff DM, Kantor AZ, Crouch JM, Ahrens KR. Sex education for transgender and non-binary youth: previous experiences and recommended content. J Sex Med. 2019;16:1834–48.
Doorduin T, Van Berlo W. Trans people’s experience of sexuality in the Netherlands: a pilot study. J Homosex. 2014;61:654–72.
Olson J, Schrager SM, Belzer M, Lisa KS, Clark LF. Baseline physiological and psychosocial characteristics of transgender youth seeking for gender dysphoria. J Adolesc Health. 2015;51:374–80.
Bungener SL, Steensma TD, Cohen-Kettenis PT, De Vries ALC. Sexual and romantic experiences of transgender youth before gender-affirmative treatment. Pediatrics. 2017;139:3.
Sumia M, Lindberg N, Työläjärvi M, Kaltiala-Heino R. Current and recalled childhood gender identity in community youth in comparison to referred adolescents seeking sex reassignment. J Adolescence. 2017;56:34–9.
Fisher AD, Ristori J, Bandini E, Giordano S, Mosconi M, Jannini EA, et al. Medical treatment in gender dysphoric adolescents endorsed by SIAMS-SIE-SIEDP-ONIG. J Endocrinological Investig. 2014;37:675–87.
World Health Organization. WHO recommendations on adolescent sexual and reproductive health and rights. 2018.
Garofalo R, Deleon J, Osmer E, Doll M, Harper GW. Overlooked, misunderstood and at-risk: exploring the lives and HIV risk of ethnic minority male-to-female transgender youth. J Adolesc Health. 2006;38:230–6.
Hoxmeier JC. Sexual assault and relationship abuse victimization of transgender undergraduate students in a national sample. Violence Gend. 2016;3:202–7.
Veale J, Watson RJ, Adjei J, Saewyc E. Prevalence of pregnancy involvement among Canadian transgender youth and its relation to mental health, sexual health, and gender identity. Int J Transgend. 2016;17:107–13.
Reisner SL, Vetters R, Leclerc M, Zaslow S, Wolfrum S, Shumer D, et al. Mental health of transgender youth in care at an adolescent urban community health center: a matched retrospective cohort study. J Adolesc Health. 2015;56:274–9.
Fisher AD, Ristori J, Castellini G, Sensi C, Cassioli E, Prunas A, et al. Psychological characteristics of italian gender dysphoric adolescents: a case-control study. J Endocrinol Invest. 2017;40:953–65.
Savioja H, Helminen M, Fröjd S, Marttunen M, Kaltiala-Heino R. Sexual experience and self-reported depression across adolescent years. Health Psychol Behav Med. 2015;3:337–47.
Savioja H, Helminen M, Frojd S, Marttunen M, Kaltiala-Heino R. Delinquency and sexual experiences across adolescence: does depression play a role? Eur J Contracept Reprod Health Care. 2017;22:298–304.
Deogracias JJ, Johnson LL, Meyer-Bahlburg HF, Kessler SJ, Schober JM, Zucker KJ. The Gender Identity/Gender Dysphoria Questionnaire for adolescents and adults. J Sex Res. 2007;44:370–9.
Achenbach TM. Integrative guide for the 1991 CBCL/4-18, YSR, and TRF profiles. Department of Psychiatry, University of Vermont; 1994.
Frigerio A, Cattaneo C, Cataldo M, Schiatti A, Molteni M, Battaglia M. Behavioral and emotional problems among Italian children and adolescents aged 4 to 18 years as reported by parents and teachers. Eur J Psychol Assess. 2004;20:124–33.
Cuzzolaro M, Vetrone G, Marano G, Garfinkel PE. The Body Uneasiness Test (BUT): development and validation of a new body image assessment scale. Eat Weight Disord. 2006;11:1–13.
IBM CR. IBM SPSS Statistics for Windows, Version Q3 25.0. Armonk, NY: IBM Corp; 2017.
De Graaf N, Giovanardi G, Zitz C, Carmichael P. Sex ratio in children and adolescents referred to the gender identity development service in the UK (2009-2016). Arch Sex Behav. 2018;47:1301–4.
Chiniara LN, Bonifacio HJ, Palmert MR. Characteristics of adolescents referred to a gender clinic: are youth seen now different from those in initial reports? Horm Res Paediatr. 2018;89:434–41.
Steensma TD, Cohen-Kettenis PT, Zucker KJ. Evidence for a change in the sex ratio of children referred for gender dysphoria: data from the center of expertise on gender dysphoria in Amsterdam (1988-2016). J Sex Marital Ther. 2018;44:713–5.
Zucker KJ. Epidemiology of gender dysphoria and transgender identity. Sex Health. 2017;14:404–11.
Aitken M, Steensma TD, Blanchard R, VanderLaan DP, Wood H, Fuentes A, et al. Evidence for an altered sex ratio in clinic‐referred adolescents with gender dysphoria. J Sex Med. 2015;12:756–63.
Ristori J, Cocchetti C, Castellini G, Pierdominici M, Cipriani A, Testi D, et al. Hormonal treatment effect on sexual distress in transgender persons: 2-year follow-up data. J Sex Med. 2020;17:142–51.
Fisher AD, Castellini G, Bandini E, Casale H, Fanni E, Benni L, et al. Cross-sex hormonal treatment and body uneasiness in individuals with gender dysphoria. J Sex Med. 2014;11:709–19.
Fisher AD, Castellini G, Ristori J, Casale H, Cassioli E, Sensi C, et al. Cross-sex hormone treatment and psychobiological changes in transsexual persons: two-year follow-up data. J Clin Endocrinol Metab. 2016;101:4260–9.
van de Grift TC, Cohen-Kettenis PT, Steensma TD, De Cuypere G, Richter-Appelt H, Haraldsen IR, et al. Body satisfaction and physical appearance in gender dysphoria. Arch Sex Behav. 2016;45:575–85.
van de Grift T, Cohen-Kettenis P, Elaut E, De Cuypere G, Richter-Appelt H, Haraldsen I, et al. A network analysis of body satisfaction of people with gender dysphoria. Body Image. 2016;17:184–90.
Becker I, Nieder TO, Cerwenka S, Briken P, Kreukels BP, Cohen-Kettenis PT, et al. Body image in young gender dysphoric adults: a European multicenter study. Arch Sex Behav. 2016;45:559–74.
De Vries AL, Doreleijers TA, Steensma TD, Cohen‐Kettenis PT. Psychiatric comorbidity in gender dysphoric adolescents. J Child Psychol Psychiatry. 2011;52:1195–202.
De Vries AL, Steensma TD, Doreleijers TA, Cohen‐Kettenis PT. Puberty suppression in adolescents with gender identity disorder: a prospective follow‐up study. J Sex Med. 2011;8:2276–83.
Skagerberg E, Parkinson R, Carmichael P. Self-harming thoughts and behaviors in a group of children and adolescents with gender dysphoria. Int J Transgend. 2013;14:86–92.
Kaltiala-Heino R, Työläjärvi M, Lindberg N. Sexual experiences of clinically referred adolescents with features of gender dysphoria. Clin Child Psychol. 2019;24:365–78.
Zucker KJ, Bradley SJ, Owen-Anderson A, Kibblewhite SJ, Wood H, Singh D, et al. Demographics, behavior problems, and psychosexual characteristics of adolescents with gender identity disorder or transvestic fetishism. J Sex Marital Ther. 2012;38:151–89.
De Vries AL, Steensma TD, Cohen-Kettenis PT, VanderLaan DP, Zucker KJ. Poor peer relations predict parent-and self-reported behavioral and emotional problems of adolescents with gender dysphoria: a cross-national, cross-clinic comparative analysis. Eur Child Adolesc Psychiatry. 2016;25:579–88.
Spack NP, Edwards-Leeper L, Feldman HA, Leibowitz S, Mandel F, Diamond DA, et al. Children and adolescents with gender identity disorder referred to a pediatric medical center. Pediatrics. 2012;129:418–25.
Grossman AH, D'Augelli AR. Transgender youth and life‐threatening behaviors. Suicide Life Threat Behav. 2007;37:527–37.
Steensma TD, Zucker KJ, Kreukels BP, VanderLaan DP, Wood H, Fuentes A, et al. Behavioral and emotional problems on the Teacher’s Report Form: a cross-national, crossclinic comparative analysis of gender dysphoric children and adolescents. J Abnorm Child Psychol. 2014;42:635–47.
Newcomb ME, Feinstein BA, Matson M, Macapagal K, Mustanski B. “I have no idea what’s going on out there:” parents’ perspectives on promoting sexual health in lesbian, gay, bisexual, and transgender adolescents. Sex Res Soc Policy. 2018;15:111–22.
Smith YLS, Van Goozen SHM, Kuiper AJ, Cohen-Kettenis PT. Sex reassignment: outcomes and predictors of treatment for adolescent and adult transsexuals. Psychol Med. 2005;35:89–99.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare no competing interests.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Ristori, J., Rossi, E., Cocchetti, C. et al. Sexual habits among Italian transgender adolescents: a cross-sectional study. Int J Impot Res 33, 687–693 (2021). https://doi.org/10.1038/s41443-021-00427-6
Received:
Revised:
Accepted:
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s41443-021-00427-6


