Table 5 Studies that have identified the relationship between testosterone and urinary stones.
Resource | Country | Age (range), year | Patients, (cases / controls) | Results |
|---|---|---|---|---|
Li J-Y et al. [6] | China | 24–37 | 37/31 | Total (13.29 ng/mL vs. 7.30 ng/mL; p < 0.001) and free testosterone levels (63.23 ng/mL vs. 35.59 ng/mL; p < 0.001) were greater in men with kidney stones |
Huang F et al. [9] | United States | ≥20 | 688/5945 | Serum testosterone levels were inversely associated with the prevalence of kidney stones in men older than 40 years |
Nackeeran S et al. [8] | United States | ≥20 | 544/4392 | Low testosterone, defined as ≤300 ng/dL, was not associated with a history of kidney stones. |
Naghii MR et al. [27] | Iran | 21–60 | 40/46 | Total testosterone (2.41 ng/mL vs. 3.30 ng/mL; p = 0.03) was greater in men with kidney stones |
Gupta K et al. [28] | India | 20–52 | 78/30 | Serum testosterone levels were greater in men with kidney stones (n = 78) than in healthy control participants (n = 30) (4.36 vs. 5.52 ng/mL; p = 0.02) |
Justin MW et al. [29] | United States | 30/25 | Total concentration (384 vs. 346 ng/dL, p = 0.112) was greater in men with kidney disease | |
Alper O et al. [30] | Turkey | 24–67 | 313/200 | Serum testosterone level was lower in stone-forming patients than in control subjects |
Emre CP et al. [31] | Turkey | 19–59 | 200/168 | Testosterone deficiency was also more frequent in patients with urinary stone disease (OR = 2.38, p = 0.041). |
Yucel E et al. [32] | United States | ≥20 | 877/7749 | Men with lower testosterone levels (<3.0 ng/mL) were less likely to have kidney stones than men with normal testosterone levels (≥3.0 ng/mL) (OR: 0.59, 95% CI 0.40–0.86) |
