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  • Perspective
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Rethinking the peyronie’s disease questionnaire: a perspective on inclusivity in sexual health assessment

Abstract

The Peyronie’s Disease Questionnaire (PDQ) has been instrumental in providing standardized, patient-centered evaluation of Peyronie’s disease. However, the evolving understanding of sexual health and diversity invites a re-examination of this tool’s underlying assumptions. This Perspective discusses the PDQ’s current framework, its contributions, and its limitations, particularly in capturing the heterogeneity of patients’ sexual experiences. Drawing from the developmental pathways of other sexual health instruments, we reflect on the importance of inclusivity in questionnaire design and the potential benefits of future revisions or alternative tools that better reflect contemporary clinical and sociocultural realities.

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References

  1. Hellstrom WJG, Feldman R, Rosen RC, Smith T, Kaufman G, Tursi J. Bother and distress associated with peyronie’s disease: validation of the peyronie’s disease questionnaire. J Urol. 2013;190:627–34. https://doi.org/10.1016/j.juro.2013.01.090

    Article  PubMed  Google Scholar 

  2. García-Gómez B, Martínez-Salamanca JI, Sarquella-Geli J, Justo-Quintas J, García-Rojo E, Fernández-Pascual E, et al. Peyronie’s disease questionnaire (PDQ): Spanish translation and validation. Int J Impot Res. 2022;34:501–4. https://doi.org/10.1038/s41443-021-00460-5

    Article  PubMed  Google Scholar 

  3. Traunero F, Di Grazia M, Ongaro L, Rizzo M, Cocci A, Verze P, et al. Validation of the Italian version of the peyronie’s disease questionnaire (PDQ). Int J Impot Res. 2023;36:588–91. https://doi.org/10.1038/s41443-023-00792-4

    Article  PubMed  Google Scholar 

  4. Coyne K, Mandalia S, McCullough S, Catalan J, Noestlinger C, Colebunders R, et al. The international index of erectile function: development of an adapted tool for use in HIV-positive men who have sex with men. J Sex Med. 2010;7:769–74. https://doi.org/10.1111/j.1743-6109.2009.01579.x

    Article  PubMed  Google Scholar 

  5. Kiss MJ, McDonagh LK, Sparks B, Hamp T, Morrison TG. Accurately assessing gay men’s erectile functioning: a critique of the international index of erectile function (IIEF) use with gay men. J Sex Res. 2021;58:589–98. https://doi.org/10.1080/00224499.2020.1811195

    Article  PubMed  Google Scholar 

  6. Cueto-Galdames B, Cifuentes M, Vedovo F, Sacomori C. Cross-cultural adaptation and face validation of the chilean version of the operated male to female sexual function index. Int Urogynecol J. 2024;35:1271–80. https://doi.org/10.1007/s00192-024-05805-4

    Article  PubMed  Google Scholar 

  7. Boehmer U, Timm A, Ozonoff A, Potter J. Applying the female sexual functioning index to sexual minority women. J Womens Health. 2012;21:401–9. https://doi.org/10.1089/jwh.2011.3072

    Article  Google Scholar 

  8. Coyne KS, Currie BM, Thompson CL, Smith TM. The psychometric validation of the peyronie’s disease questionnaire (PDQ). Int J Impot Res. 2013;25:190–9. https://doi.org/10.1038/ijir.2013.7

    Article  Google Scholar 

  9. Masterson TA, Efimenko IV, Nackeeran S, Parmar M, Ramasamy R. Discordant erectile function assessment between validated questionnaire scores and penile doppler ultrasound in Peyronie’s disease. Int J Impot Res. 2022;34:452–5. https://doi.org/10.1038/s41443-021-00416-9

    Article  PubMed  Google Scholar 

  10. Kadioğlu A, Tefekli A, Erol H, Cayan S, Kandirali E. Color Doppler ultrasound assessment of penile vascular system in men with Peyronie’s disease. Int J Impot Res. 2000;12:263–7. https://doi.org/10.1038/sj.ijir.3900569

    Article  PubMed  Google Scholar 

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The author declares that no funding was received for the preparation of this manuscript.

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EV contributed to the writing of the manuscript. SW conceived and supervised the writing. AC, MP, MLR, and KVR contributed to the critical revision of the manuscript.

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Correspondence to E. Vannier.

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Vannier, E., Cocci, A., Pezzoli, M. et al. Rethinking the peyronie’s disease questionnaire: a perspective on inclusivity in sexual health assessment. Int J Impot Res (2025). https://doi.org/10.1038/s41443-025-01216-1

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