Urogenital diseases - Latest research and news

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Latest Research and Reviews

Sperm DNA fragmentation and its influence on mammalian reproduction

In this Review, the authors synthesize current understanding of sperm DNA fragmentation and its effects on mammalian reproduction. Reproductive consequences for fertilization, embryo development, and pregnancy outcomes and strategies aimed at reducing or preventing DNA fragmentation are examined.
- Mehran Dabiri
- Dale M. Goss
- Majid Ebrahimi Warkiani
Reviews28 Jan 2026 Nature Reviews Urology
P: 1-28
Efficacy of the new P100 extracorporeal shock wave therapy device in the treatment of type IIIB chronic prostatitis/chronic pelvic pain syndrome: a sham treatment controlled, prospective clinical trial
- Haipeng Zhang
- Wei Song
- Bo Peng
Research28 Jan 2026 Prostate Cancer and Prostatic Diseases
P: 1-10
Parkin deficiency impairs female fertility, oocyte development, fertilization and mitochondrial function in mice
- Michelle Volovsky
- Adolfo Rodríguez-Eguren
- Emre Seli
ResearchOpen Access22 Jan 2026 npj Aging
P:
Multi-modal ultrasound for evaluating structure and function of neurogenic bladder in pediatrics
- Junkui Wang
- Miao Wang
- Jianguo Wen
ResearchOpen Access17 Jan 2026 Scientific Reports
P:
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate

The study identifies cavernosal lactate as a driver of diabetes-induced erectile dysfunction through FBP1 dysfunction, histone methylation and palmitoylation.
- Ming Xiao
- Wanyang Guo
- Xin Jin
ResearchOpen Access16 Jan 2026 Nature Communications
P:
Genomics reveal Staphylococcus aureus persists during long-term urinary catheterization despite antimicrobial therapy and catheter exchanges

With whole-genome sequencing of longitudinal Staphylococcus aureus isolates collected from long-term urinary catheters, authors show that the same strain of multidrug resistant S. aureus persists asymptomatically long-term despite antibiotic exposures.
- Jesus M. Duran Ramirez
- Chelsie E. Armbruster
- Jennifer N. Walker
ResearchOpen Access13 Jan 2026 Nature Communications
P:

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News and Comment

Response to comment on: A novel rat model for investigating erectile function after nerve-sparing radical prostatectomy
- Yashou Guo
- Ronggui Tao
- Dalin He
Comments & Opinion08 Jan 2026 International Journal of Impotence Research
P: 1-2
Response to Comment on: Heme reduces corpus cavernosum smooth muscle contraction via the HO-CO-sGC-cGMP pathway: implications for priapism in sickle cell disease
- Dalila Andrade Pereira
- Fábio Henrique Silva
Comments & Opinion17 Dec 2025 International Journal of Impotence Research
P: 1-2
Technical modifications to improve erectile function recovery after radical prostatectomy

Posterior nerve-sparing modifications during radical prostatectomy aim to improve preservation of the cavernous nerves and microvasculature to enhance postoperative erectile recovery. Current techniques for this are associated with varied functional outcomes and have a number of key anatomical and technical considerations.
- Suma Gangidi
- Gal Wald
- Jim C. Hu
Comments & Opinion08 Dec 2025 Nature Reviews Urology
P: 1-3
EMUC25: shaping tomorrow’s uro-oncology care
- Maria Chiara Masone
Research Highlights05 Dec 2025 Nature Reviews Urology
Volume: 23, P: 9
Comment on: Quality of life outcomes following penile prosthesis insertion in the post-ischaemic priapism setting
- Borja García Gómez
Comments & Opinion26 Nov 2025 International Journal of Impotence Research
P: 1-2
Comment on: reservoir migration in inflatable penile prostheses: a systematic review and development of a clinical decision algorithm
- Eric Chung
- Nicholas Gillman
Comments & Opinion13 Nov 2025 International Journal of Impotence Research
P: 1-2

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Urogenital diseases articles from across Nature Portfolio

Related Subjects

Latest Research and Reviews

Sperm DNA fragmentation and its influence on mammalian reproduction

Efficacy of the new P100 extracorporeal shock wave therapy device in the treatment of type IIIB chronic prostatitis/chronic pelvic pain syndrome: a sham treatment controlled, prospective clinical trial

Parkin deficiency impairs female fertility, oocyte development, fertilization and mitochondrial function in mice

Multi-modal ultrasound for evaluating structure and function of neurogenic bladder in pediatrics

Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate

Genomics reveal Staphylococcus aureus persists during long-term urinary catheterization despite antimicrobial therapy and catheter exchanges

News and Comment

Response to comment on: A novel rat model for investigating erectile function after nerve-sparing radical prostatectomy

Response to Comment on: Heme reduces corpus cavernosum smooth muscle contraction via the HO-CO-sGC-cGMP pathway: implications for priapism in sickle cell disease

Technical modifications to improve erectile function recovery after radical prostatectomy

EMUC25: shaping tomorrow’s uro-oncology care

Comment on: Quality of life outcomes following penile prosthesis insertion in the post-ischaemic priapism setting

Comment on: reservoir migration in inflatable penile prostheses: a systematic review and development of a clinical decision algorithm

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