Fig. 4: NiH-catalyzed enantioselective hydroalkynylation of styrenes with bromoalkynes. | Nature Communications

Fig. 4: NiH-catalyzed enantioselective hydroalkynylation of styrenes with bromoalkynes.

From: Nickel-catalysed migratory hydroalkynylation and enantioselective hydroalkynylation of olefins with bromoalkynes

Fig. 4

Yield under each product refers to the isolated yield of purified product (0.20 mmol scale, average of two runs), single regioisomer was obtained unless otherwise noted. Enantioselectivities were determined by chiral HPLC analysis. *NiBr2·diglyme used as catalyst, 1,2-dichloroethane used as solvent, 3.0 equiv NaI used. TES triethylsilyl.

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